The radiological pituitary lesion may reflect nonadenomatous causes, which include cysts (eg, Rathke cleft cyst, which is usually in the midline), vascular changes, or other local pathological neoplastic or inflammatory processes. (medscape.com)
Subtypes1
In this section the general characteristics of pituitary adenomas are discussed, followed by separate sections on subtypes of pituitary adenomas, pituitary neuroendocrine tumors grading, and pituitary carcinomas. (medscape.com)
Dive into the research topics of 'Silent corticotroph adenoma with multiple cysts: Pars intermedia tumor? (elsevierpure.com)
Pituicytoma, granular cell tumor of the neurohypophysis, and spindle cell oncocytoma are nonneuroendocrine tumors arising in the posterior pituitary and occur much less frequently than pituitary adenomas. (medscape.com)
Prevalence1
This is despite the high prevalence of occult pituitary adenomas in the general population, the widespread use of high definition imaging techniques, and the broad range of intra- and perisellar lesions that can mimic pituitary adenomas. (bmj.com)
Occult1
Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population. (medscape.com)
Visual field deficits1
Inappropriate pituitary hormone secretion and visual field deficits are the most characteristic presenting features of pituitary adenomas. (bmj.com)
Silent1
So-called "silent adenomas", in which abnormal hormone gene activity is not accompanied by excessive hormone secretion, tend to be more aggressive than truly inactive adenomas. (bmj.com)
Classification1
Buurman H, Saeger W. Subclinical adenomas in postmortem pituitaries: classification and correlations to clinical data. (medscape.com)
Aggressive1
[ 3 ] Pituitary adenomas are uncommon in the pediatric population, but most tumors of childhood are clinically functioning adenomas and are thought to be more aggressive. (medscape.com)
Normal1
Note the delicate acinar pattern of a normal pituitary gland (left), in contrast with disruption of the normal reticulin network in adenoma (right) (Wilder reticulin stain). (medscape.com)
Pituitary adenomas14
Tumors of the pituitary gland and sellar region represent approximately 10-15% of all brain tumors,[2] of which the great majority in this region are pituitary adenomas. (medscape.com)
3] Pituitary adenomas are uncommon in the pediatric population, but most tumors of childhood are clinically functioning adenomas and are thought to be more aggressive. (medscape.com)
Pituitary adenomas are neuroendocrine tumors derived from intrinsic cells of the adenohypophysis. (medscape.com)
Pituicytoma, granular cell tumor of the neurohypophysis, and spindle cell oncocytoma are nonneuroendocrine tumors arising in the posterior pituitary and occur much less frequently than pituitary adenomas. (medscape.com)
In this section the general characteristics of pituitary adenomas are discussed, followed by separate sections on subtypes of pituitary adenomas, pituitary neuroendocrine tumors grading, and pituitary carcinomas. (medscape.com)
Pituitary adenomas are classified clinically into two groups-clinically functioning adenomas and clinically nonfunctioning adenomas-according to whether an endocrine syndrome is present or absent. (medscape.com)
Much of the literature is devoted to the histological, ultrastructural, and immunocytochemical classification of pituitary adenomas (extensively supported by multicentre studies), with little consensus on the identification of prognostic features in adenomas, particularly in relation to invasion. (bmj.com)
In light of these uncertainties, an approach to the diagnosis and classification of pituitary adenomas is suggested, based on robust criteria from earlier studies and incorporating provisional data that require reassessment in large prospective studies with an adequate clinicopathological database. (bmj.com)
the most frequent of these are pituitary adenomas, which account for 6-10% of all symptomatic intracranial tumours. (bmj.com)
5, 12 The aim of this article is to provide a brief review of the clinical features of lesions that are encountered from within and around the pituitary gland, to assess current diagnostic pathological techniques, and to explore the expanding evidence base for the classification of pituitary adenomas and the clinical relevance of these approaches. (bmj.com)
Introduction: Pituitary adenomas, second most common brain tumors, are mostly well controlled after surgery. (endocrine-abstracts.org)
Pituitary adenomas consist of a group of highly heterogeneous intracranial tumours with variable presentation, clinical prognosis and management. (endocrine-abstracts.org)
Introduction: Prolactinoma is the most common secretory pituitary adenomas. (endocrine-abstracts.org)
Pituitary adenomas may secrete hormones, but most are clinically inactive. (medscape.com)
Prolactin-secretin2
Management of prolactinoma in special situations is discussed, including cystic lesions, mixed growth hormone-secreting and prolactin-secreting adenomas and giant and aggressive prolactinomas. (bvsalud.org)
Patients with prolactin-secreting adenomas may present with galactorrhea/menstrual disorders. (medscape.com)
Cleft1
Cystic lesions, such as Rathke cleft cysts, typically have a low-intensity signal on T1-weighted images, whereas on T2-weighted images, cystic lesions may have a high-intensity signal. (medscape.com)
Lesions1
There is a wide variability in the immunological reaction of the host as well as in the multiple lesions induced by the parasites [ 1 ]. (hindawi.com)
Diagnosis1
in contrast, the incidental finding of nonsecreting microadenomas is sufficiently common that the diagnosis of a corticotropin-secreting adenoma after positive clinical and biochemical testing may then require specialized tests such as petrosal sinus sampling to confirm the anatomic diagnosis. (medscape.com)
Carcinomas1
There is a lack of correspondence between clinical and pathological criteria to identify and classify invasion, and a need to reassess the nomenclature and diagnostic criteria for invasive adenomas and carcinomas. (bmj.com)
Secretory1
[ 1 ] Hormonal hypersecretion in the setting of a sellar mass is typically caused by a pituitary adenoma, and prolactin-secreting microadenomas are the most frequent secretory microadenomas. (medscape.com)
Ovarian2
At the time, laparoscopy and dye infusion had demonstrated multiple, small ovarian cysts with patent oviducts. (medscape.com)
OBJECTIVE: Functioning gonadotroph adenomas (FGAs) are rare pituitary tumours stimulating ovarian function with potential life-threatening consequences in women. (bvsalud.org)
Incidental1
2] Incidental adenomas can be found in nearly 10% of autopsied patients. (medscape.com)
Characteristics1
Association between birth characteristics and incidence of pituitary adenoma and craniopharyngioma: a registry-based study in California, 2001-2015 Cancer Causes Control. (usc.edu)
ACTH3
these include prolactin (PRL)-producing, growth hormone (GH)-producing, adrenocorticotropic hormone (ACTH)-producing, and thyroid-stimulating hormone (TSH)-producing adenomas (see Table 2, below). (medscape.com)
HN - 2006 BX - Adipose Tissue, Abdominal MH - ACTH-Secreting Pituitary Adenoma UI - D049913 MN - C4.557.470.35.12 MN - C4.588.322.609.145 MN - C10.228.140.617.738.675.149 MN - C19.344.609.145 MN - C19.700.734.145 MS - A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE. (nih.gov)
AN - coordinate IM with ADENOMA (IM) HN - 2006 BX - Corticotroph Adenoma BX - Pituitary Adenoma, ACTH-Secreting BX - Pituitary Corticotropin-Secreting Adenoma MH - Actin Capping Proteins UI - D051344 MN - D5.750.78.730.32 MN - D12.776.220.525.32 MS - Actin capping proteins are cytoskeletal proteins that bind to the ends of ACTIN FILAMENTS to regulate actin polymerization. (nih.gov)
Growth hormone1
Growth hormone-secreting adenomas cause acromegaly, with coarsening of facial features and increased width of the hands and feet. (medscape.com)
Contrast1
Note the delicate acinar pattern of a normal pituitary gland (left), in contrast with disruption of the normal reticulin network in adenoma (right) (Wilder reticulin stain). (medscape.com)
Magnetic2
Magnetic resonance imaging (MRI) demonstrated multiple cysts and a solid lesion in the sella and around the anterior clinoid process. (hindawi.com)
Computed tomography (CT) and magnetic resonance imaging (MRI) scan disclosed multiple intracranial cysts in the suprasellar area with extension to the third ventricle. (hindawi.com)
Approach1
At the second surgery, six weeks later via transnasal transsphenoidal approach a silent corticotroph pituitary adenoma was removed which was studied by histology, immunohistochemistry, and electron microscopy. (hindawi.com)