NeoplasmsCarcinomasPleomorphic adenomasTumorMucoepidermoid carcinomaMajor salivary glandsCarcinoma Ex-Pleomorphic AdenomaHyperplasiaGlandularMammaryMinor salivary glandArise in the submandibularLacrimal glandParotid glandsColonicParathyroid glandsBasal cell adenocarcinomaPathologyMalignancyAdenoid cysticLesionsTumors occurNormal adrenal glandsSebaceous gland tumorsCeruminous gland tumorsPolypEpithelialOriginateHyperplasticExtremely well-differentiatedTubularCancerous tumorsLesionOriginatesHistological examinationVillousMalignumPituitary glandColorectal adenocarcinomaCommon benignUpper aerodigestiveCancers
Neoplasms25
- Salivary gland tumors (SGTs) are uncommon and represent 2-3% of head and neck neoplasms. (medscape.com)
- Colorectal adenomas are intraepithelial neoplasms that characteristically display epithelial dysplasia. (anatomywarehouse.com)
- Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
- Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
- Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
- Some common salivary gland neoplasms are listed in the table below. (medscape.com)
- Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
- [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 5.5 cases per 100,000 individuals in the United States, with malignant neoplasms accounting for 0.9 cases per 100,000. (medscape.com)
- Salivary gland neoplasms most commonly appear in the sixth decade of life. (medscape.com)
- Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
- Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
- The most common tumor of the parotid gland is the pleomorphic adenoma , which represents about 60% of all parotid neoplasms, as seen in the table below. (medscape.com)
- Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
- Salivary gland neoplasms are rare in children. (medscape.com)
- In children, 35% of salivary gland neoplasms are malignant. (medscape.com)
- Contrasting information was derived through a literature review by Louredo et al, which indicated that in pediatric patients, most salivary gland neoplasms (75.4%) are malignant. (medscape.com)
- Salivary gland neoplasms occurred with slightly greater frequency in girls (57.4% of patients) than in boys. (medscape.com)
- Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are benign and malignant, basaloid salivary gland neoplasms, respectively. (biomedcentral.com)
- BCA carries a favorable prognosis in comparison with other salivary gland neoplasms, especially since recurrence is not common. (e-acfs.org)
- 20 mm in diameter were histologically confirmed as malignant neoplasms (pheochromocytoma and adenocarcinoma). (biomedcentral.com)
- In general, salivary gland neoplasms respond poorly to chemotherapy, and adjuvant chemotherapy is currently indicated only for palliation. (medscape.com)
- Recent reports have shown that neutron-based radiation therapy may be more effective than photon-based radiation therapy for the treatment of malignant salivary gland neoplasms with gross disease and provides excellent local and regional control of microscopic disease. (medscape.com)
- [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 1.5 cases per 100,000 individuals in the United States. (medscape.com)
- The etiology of salivary gland neoplasms is not fully understood. (medscape.com)
- Recent evidence suggests that the bicellular stem cell theory is the more probable etiology of salivary gland neoplasms. (medscape.com)
Carcinomas7
- The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
- However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)
- Using a platinum-based agent, cisplatin, and an antimicrotubule drug, docetaxel, with radiation shows some promise in advanced carcinomas of the salivary gland. (medscape.com)
- Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
- Squamous cell carcinomas arise from excretory duct cells, pleomorphic adenomas arise from the intercalated duct cells, oncocytomas arise from the striated duct cells, and acinic cell carcinomas arise from acinar cells. (medscape.com)
- Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted therapies. (cdc.gov)
- The pleomorphic adenoma (PA) is the most common tumor affection the salivary glands 7,8 , accounting for 33.2% to 89.9% of the cases, followed by carcinomas. (bvsalud.org)
Pleomorphic adenomas6
- The group of benign tumours included 164 pleomorphic adenomas, 51 Warthin's tumours, 7 basal cell adenomas, 2 lipomas as well as 5 other different tumours. (researchgate.net)
- In three cases which initially were taken for pleomorphic adenomas by routine histological examination, aneuploid cell populations exposed by DNA flow cytometric analysis gave rise to a closer inspection of the suspect lesions. (researchgate.net)
- A study from the Netherlands, by Valstar et al, found an overall 20-year recurrence rate for salivary gland pleomorphic adenomas of 6.7%, with the first recurrence arising at a median of 7 years. (medscape.com)
- Those located in the minor salivary glands had a lower recurrence risk than did pleomorphic adenomas in the parotid glands. (medscape.com)
- Most tumors (65%) are benign, with hemangiomas being the most common, followed by pleomorphic adenomas. (medscape.com)
- This therapy has been proven to have good local control and survival rates in patients with grossly recurrent pleomorphic adenomas that cannot be resected. (medscape.com)
Tumor11
- Almost 85% of these cases are caused by a benign tumor on the pituitary gland. (sitstay.com)
- The tumor causes the pituitary gland to continuously send a signal to the adrenal glands to keep releasing cortisol into the bloodstream. (sitstay.com)
- The other 10-15% of Cushing's Disease cases are caused by a tumor that forms on the adrenal gland itself. (sitstay.com)
- The tumor can be benign (adenoma) or malignant (adenocarcinoma). (sitstay.com)
- That is, as the size of the gland decreases, the incidence of malignancy of a tumor in the gland increases in approximately these proportions. (medscape.com)
- Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
- Perianal adenoma /adenosarcoma: Originating in the tiny skin glands around the anus, this tumor is typically benign (adenoma), but the malignant version is possible too (adenosarcoma), particularly those that arise from the anal gland tissue itself. (embracepetinsurance.com)
- Despite its low incidence, basal cell adenoma is the third most common benign tumor of the salivary gland after pleomorphic adenoma and Warthin's tumor. (e-acfs.org)
- BCA is histologically similar to other tumors, such as pleomorphic adenoma, Warthin's tumor, and basal cell adenocarcinoma (BCAC). (e-acfs.org)
- Found in male dogs, this tumor develops in the prostate gland. (thevetexpert.com)
- In the multicellular theory, each tumor type is associated with a specific differentiated cell of origin within the salivary gland unit. (medscape.com)
Mucoepidermoid carcinoma3
- The malignant tumors include ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma. (wikipedia.org)
- Mucoepidermoid carcinoma is the most common salivary gland malignancy in children. (medscape.com)
- The incisional biopsy revealed a typical pleomorphic adenoma with focal areas of nests of epidermoid and mucous cells, as well as microcyst formations, resembling the mucoepidermoid carcinoma (MEC). (bvsalud.org)
Major salivary glands2
- The salivary glands are divided into 2 groups: the major salivary glands and the minor salivary glands. (medscape.com)
- The major salivary glands consist of the following 3 pairs of glands: the parotid glands, the submandibular glands, and the sublingual glands. (medscape.com)
Carcinoma Ex-Pleomorphic Adenoma1
- Carcinoma Ex-Pleomorphic Adenoma (CExPA) is a salivary gland carcinoma derived from a primary or recurrent benign pleomorphic adenoma (PA) extremely rare in minor salivary glands. (bvsalud.org)
Hyperplasia5
- Primary hyperparathyroidism can be caused by adenoma, adenocarcinoma, parathyroid hyperplasia or ectopic parathyroid glands. (endocrine-abstracts.org)
- In a study that evaluated adrenal size in populations of dogs under 10 kg with and without hyperadrenocorticism, a cut off of 0.6 cm thickness of the caudal pole of the adrenal gland was 75% sensitive and 94% specific for differentiating normal adrenal glands from adrenal hyperplasia. (vin.com)
- Focal adrenal nodules and masses (unilateral or bilateral): hyperplasia, adenoma. (vin.com)
- Lesions based on histology were classified as cortical adrenal hyperplasia ( n = 67), adenocarcinoma ( n = 17), pheochromocytoma ( n = 10), metastases ( n = 7), adrenal adenoma ( n = 4), and adrenalitis ( n = 4). (biomedcentral.com)
- Benign Mimics of Invasive Adenocarcinoma of the Cervix Tunnel Clusters Microglandular Hyperplasia Mesonephric Hyperplasia Endocervical Glandular Hyperplasias Arias-Stella ReactionTunnel Clusters Fluhmann first introduced the term "tunnel cluster" in his description of thehistology of the endocervix (2;3). (fliphtml5.com)
Glandular4
- Adenocarcinomas are cancers that originate in glandular tissue cells. (medlineplus.gov)
- Using tissue microarrays and full tissue sections of normal and 448 neoplastic tissues, HE4 immunoreactivity was found in normal glandular epithelium of the female genital tract and breast, the epididymis and vas deferens, respiratory epithelium, distal renal tubules, colonic mucosa, and salivary glands, consistent with HE4 gene expression. (nature.com)
- 2Introduction The distinction between benign proliferative glandular lesions of the endocervixand well-differentiated invasive cervical adenocarcinoma continues to be problematic, ashighlighted by the number of reports in the literature considering this diagnostic issue.Interestingly, the relatively recent recognition of a number of potential mimics ofinvasive adenocarcinoma of the endocervix underscores the likelihood that in the pastmany of these benign yet floridly proliferative lesions have been mistaken for invasiveadenocarcinoma. (fliphtml5.com)
- For instance, in one institutional review five cases diagnosed asinvasive adenocarcinoma over a 14-year period were reclassified as benign mimics (1).Although a variety of immunoperoxidase stains have been tried, ultimately therecognition of benign pseudoneoplastic glandular lesions of the cervix rests upon theirdistinctive histologic features. (fliphtml5.com)
Mammary4
- Picture of the udder of a 22-month-old 568.2-kg (1,250-lb) Clydesdale filly referred to the Purdue University Veterinary Teaching Hospital because of a 3-month history of an enlarged left mammary gland. (avma.org)
- Percutaneous lateromedial ultrasonographic image of the enlarged left mammary gland of the filly described in Figure 1 showing an accumulation of fluid (black arrow) in the mammary gland, homogeneously hyperechoic mammary tissue (double-headed arrow), and the medial lamina (white arrows) between the 2 halves of the udder. (avma.org)
- For instance, mammary gland adenocarcinomas in female dogs are often influenced by hormonal changes, and the risk can be reduced through spaying (ovariohysterectomy). (thevetexpert.com)
- Arises from the mammary glands can be found in both male and female dogs. (thevetexpert.com)
Minor salivary gland1
- The aim of this study was to report a clinical case of pleomorphic adenoma affecting the minor salivary gland and to discuss its characteristics, emphasizing the important role of the dentist in the correct and early diagnosis of this lesion, resulting in a more conservative treatment and better prognosis for the patient. (bvsalud.org)
Arise in the submandibular1
- the remaining SGTs arise in the submandibular, sublingual, and minor salivary glands. (medscape.com)
Lacrimal gland3
- A case of an in situ adenocarcinoma of the lacrimal gland that developed in a recurring pleomorphic adenoma is presented. (eyehospital.nl)
- An orbital computerized tomography scan showed an inhomogeneous mass in the right lacrimal gland region without bone involvement. (eyehospital.nl)
- Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma. (cdc.gov)
Parotid glands1
- Head and neck cancer is cancer that starts in the lip, oral cavity (mouth), nasal cavity (inside the nose), paranasal sinuses, pharynx, larynx or parotid glands. (icd.codes)
Colonic1
- This is an example of a tubular colonic adenoma. (anatomywarehouse.com)
Parathyroid glands1
- Cervical ultrasonography to assess the parathyroid glands revealed no abnormalities. (dvm360.com)
Basal cell adenocarcinoma1
- Due to the prognosis, differential diagnosis with basal cell adenocarcinoma, adenoid cystic carcinoma and basaloid squamous cell carcinoma is required. (e-acfs.org)
Pathology2
- In both cases, the mass was completely excised, postoperative pathology reports confirmed the diagnosis of basal cell adenoma. (e-acfs.org)
- Kaku, T & Enjoji, M 1983, ' Extremely well-differentiated adenocarcinoma ("Adenoma malignum") of the cervix ', International Journal of Gynecological Pathology , vol. 2, no. 1, pp. 28-41. (elsevierpure.com)
Malignancy2
- Adenocarcinoma: This malignancy can arise from any of the tissues of the GI system, but the stomach and intestines are predisposed. (embracepetinsurance.com)
- Platinum-based agents, in combination with mitoxantrone or vinorelbine, are also effective in controlling recurrent salivary gland malignancy. (medscape.com)
Adenoid cystic2
- Using paclitaxel (Taxol), another antimicrotubule drug, alone has had moderate activity against mucoepidermoid tumors and adenocarcinomas but no effect adenoid cystic carcinoma. (medscape.com)
- Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. (cdc.gov)
Lesions8
- [ 7 ] They stressed surgical landmarks for avoiding injury to the main trunk and branches of the facial nerve and advocated complete removal of the superficial portion of the parotid gland for noninvasive lesions confined to that portion of the gland. (medscape.com)
- However, up to 40% of lesions larger than 4cm in diameter progress to adenocarcinoma. (anatomywarehouse.com)
- The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions. (researchgate.net)
- Ultrasonography to visualize adrenal gland lesions and evaluate incidentally discovered adrenal masses in dogs has become more reliable with advances in imaging techniques. (biomedcentral.com)
- The goal of our study was to investigate which ultrasound features of adrenal gland abnormalities could aid in discriminating between benign and malignant lesions. (biomedcentral.com)
- Adrenal gland lesions (nodules and masses) commonly develop in older dogs, but surgery is indicated in only a small fraction of such cases, usually in malignant and hormone-secreting tumors [ 13 ]. (biomedcentral.com)
- many of these benign yet floridly proliferative lesions have been mistaken for invasive adenocarcinoma. (fliphtml5.com)
- Some lesions of the salivary glands exhibit similar clinical, histopathological and imaging aspects, which can compose a differential diagnosis of PA 6 . (bvsalud.org)
Tumors occur1
- An estimated 700 deaths (0.4 per 100,000 for males and 0.2 per 100,000 for females) related to salivary gland tumors occur annually. (medscape.com)
Normal adrenal glands1
- Of these, 50 dogs had normal adrenal glands whereas 69 showed pathological ones. (biomedcentral.com)
Sebaceous gland tumors2
- Among these, papillomas, sebaceous gland tumors, mast cell tumors and lipomas are the most frequent in dogs. (vetinfo.com)
- Nonmalignant disorders include café-au-lait spots and sebaceous gland tumors. (msdmanuals.com)
Ceruminous gland tumors1
- Ceruminous gland tumors are best visualized in a clean ear using a video otoscope. (merckvetmanual.com)
Polyp1
- Regular surveillance colonoscopy in at risk groups with polyp removal reduces incidence of adenocarcinoma. (anatomywarehouse.com)
Epithelial3
- Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. (nature.com)
- Adenocarcinoma in dogs is a type of cancer that originates in epithelial tissues. (thevetexpert.com)
- Adenocarcinomas can occur in different organs and tissues and are characterized by the uncontrolled growth and spread of abnormal epithelial cells. (thevetexpert.com)
Originate1
- Primary liver tumors (those that originate in the liver) are most typically bile duct adenocarcinomas, but plenty of tumors (from the GI system and spleen, for example) like to metastasize here, setting up secondary residence. (embracepetinsurance.com)
Hyperplastic2
- 20 mm in diameter and nodular in shape were often identified as cortical hyperplastic nodules or adenomas. (biomedcentral.com)
- Fluhmann attributed tunnel clusters to the involution ofendocervical glands (crypts) that had become hyperplastic as a response to the alteredhormonal milieu of pregnancy. (fliphtml5.com)
Extremely well-differentiated2
- Eight cases of extremely well-differentiated adenocarcinoma of the cervix were collected for clinicohistopathologic study. (elsevierpure.com)
- The lattercan be particularly alarming if one is not aware that this type of change can occur (4).The main differential diagnosis is with extremely well-differentiated endocervicaladenocarcinoma (adenoma malignum). (fliphtml5.com)
Tubular2
- Ceruminous glands are simple, coiled, tubular glands made up of an inner secretory layer of cells and an outer myoepithelial layer of cells. (wikipedia.org)
- Tubular adenomas tend to be small, pedunculated polys composed of rounded or tubular glands. (anatomywarehouse.com)
Cancerous tumors1
- cancerous tumors of the glands, such as in the ducts or lobules of the breast. (thewomenofhope.org)
Lesion3
- If lesion is greater than 2.0 cm in diameter, there is increased likelihood of neoplastic etiology (adenocarcinoma, pheochromocytoma) versus benign causes. (vin.com)
- Abnormal appearance of structural features on ultrasound images (e.g., adrenal gland lesion size, shape, laterality, and echotexture) may aid in diagnosis, but these features alone were not pathognomic. (biomedcentral.com)
- After confirming the diagnosis of pleomorphic adenoma, we opted for enucleation of the lesion to avoid possible complications such as scar retraction and salivary fistula. (bvsalud.org)
Originates1
- A good rule of thumb is that the likelihood of an SGT being malignant is inversely proportional to the size of the gland from which it originates. (medscape.com)
Histological examination1
- Clinical records of 119 dogs that had undergone ultrasound adrenal gland and histological examination were reviewed. (biomedcentral.com)
Villous1
- Villous adenomas occasionally secrete large amounts of mucoid protein and/or potassium rich fluid, leading possibly to hypokalemia. (anatomywarehouse.com)
Malignum1
- The common admixture of type A and B tunnelclusters, in combination with the predominantly lobulated architecture, absence ofdesmoplasia and lack of deep, widely infiltrative glands helps distinguish it fromadenoma malignum.Type B tunnel clusters Type B tunnel clusters also have a lobular architecture, but are composed ofdilated glands lined by cuboidal or flattened epithelium and filled with inspissated,mucinous secretions. (fliphtml5.com)
Pituitary gland1
- The pituitary gland is a very small organ located within the base of the brain that controls several other hormone-releasing glands. (sitstay.com)
Colorectal adenocarcinoma1
- There is an increased risk in patients with a positive family history of colorectal adenocarcinoma. (anatomywarehouse.com)
Common benign1
- The pleomorphic adenoma (PA) is the most common benign neoplasia in salivary glands, affecting most commonly the parotid gland of females between the 4th and 6th decades of life. (bvsalud.org)
Upper aerodigestive2
- The salivary glands exist as larger named "major" glands and also as many widely dispersed "minor" glands that exist throughout the upper aerodigestive submucosa (ie, palate, lip, pharynx, nasopharynx, larynx, and parapharyngeal space). (medscape.com)
- [ 6 ] The minor salivary glands comprise 600-1000 small glands distributed throughout the upper aerodigestive tract. (medscape.com)
Cancers2
- Most breast cancers are adenocarcinomas. (ucsfhealth.org)
- Genetic predisposition can play a role in developing various cancers, including adenocarcinomas. (thevetexpert.com)