• The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
  • However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)
  • Using a platinum-based agent, cisplatin, and an antimicrotubule drug, docetaxel, with radiation shows some promise in advanced carcinomas of the salivary gland. (medscape.com)
  • Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
  • Squamous cell carcinomas arise from excretory duct cells, pleomorphic adenomas arise from the intercalated duct cells, oncocytomas arise from the striated duct cells, and acinic cell carcinomas arise from acinar cells. (medscape.com)
  • Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted therapies. (cdc.gov)
  • The pleomorphic adenoma (PA) is the most common tumor affection the salivary glands 7,8 , accounting for 33.2% to 89.9% of the cases, followed by carcinomas. (bvsalud.org)
  • The group of benign tumours included 164 pleomorphic adenomas, 51 Warthin's tumours, 7 basal cell adenomas, 2 lipomas as well as 5 other different tumours. (researchgate.net)
  • In three cases which initially were taken for pleomorphic adenomas by routine histological examination, aneuploid cell populations exposed by DNA flow cytometric analysis gave rise to a closer inspection of the suspect lesions. (researchgate.net)
  • A study from the Netherlands, by Valstar et al, found an overall 20-year recurrence rate for salivary gland pleomorphic adenomas of 6.7%, with the first recurrence arising at a median of 7 years. (medscape.com)
  • Those located in the minor salivary glands had a lower recurrence risk than did pleomorphic adenomas in the parotid glands. (medscape.com)
  • Most tumors (65%) are benign, with hemangiomas being the most common, followed by pleomorphic adenomas. (medscape.com)
  • This therapy has been proven to have good local control and survival rates in patients with grossly recurrent pleomorphic adenomas that cannot be resected. (medscape.com)
  • Almost 85% of these cases are caused by a benign tumor on the pituitary gland. (sitstay.com)
  • The tumor causes the pituitary gland to continuously send a signal to the adrenal glands to keep releasing cortisol into the bloodstream. (sitstay.com)
  • The other 10-15% of Cushing's Disease cases are caused by a tumor that forms on the adrenal gland itself. (sitstay.com)
  • The tumor can be benign (adenoma) or malignant (adenocarcinoma). (sitstay.com)
  • That is, as the size of the gland decreases, the incidence of malignancy of a tumor in the gland increases in approximately these proportions. (medscape.com)
  • Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
  • Perianal adenoma /adenosarcoma: Originating in the tiny skin glands around the anus, this tumor is typically benign (adenoma), but the malignant version is possible too (adenosarcoma), particularly those that arise from the anal gland tissue itself. (embracepetinsurance.com)
  • Despite its low incidence, basal cell adenoma is the third most common benign tumor of the salivary gland after pleomorphic adenoma and Warthin's tumor. (e-acfs.org)
  • BCA is histologically similar to other tumors, such as pleomorphic adenoma, Warthin's tumor, and basal cell adenocarcinoma (BCAC). (e-acfs.org)
  • Found in male dogs, this tumor develops in the prostate gland. (thevetexpert.com)
  • In the multicellular theory, each tumor type is associated with a specific differentiated cell of origin within the salivary gland unit. (medscape.com)
  • Adenocarcinomas are cancers that originate in glandular tissue cells. (medlineplus.gov)
  • Using tissue microarrays and full tissue sections of normal and 448 neoplastic tissues, HE4 immunoreactivity was found in normal glandular epithelium of the female genital tract and breast, the epididymis and vas deferens, respiratory epithelium, distal renal tubules, colonic mucosa, and salivary glands, consistent with HE4 gene expression. (nature.com)
  • 2Introduction The distinction between benign proliferative glandular lesions of the endocervixand well-differentiated invasive cervical adenocarcinoma continues to be problematic, ashighlighted by the number of reports in the literature considering this diagnostic issue.Interestingly, the relatively recent recognition of a number of potential mimics ofinvasive adenocarcinoma of the endocervix underscores the likelihood that in the pastmany of these benign yet floridly proliferative lesions have been mistaken for invasiveadenocarcinoma. (fliphtml5.com)
  • For instance, in one institutional review five cases diagnosed asinvasive adenocarcinoma over a 14-year period were reclassified as benign mimics (1).Although a variety of immunoperoxidase stains have been tried, ultimately therecognition of benign pseudoneoplastic glandular lesions of the cervix rests upon theirdistinctive histologic features. (fliphtml5.com)
  • Picture of the udder of a 22-month-old 568.2-kg (1,250-lb) Clydesdale filly referred to the Purdue University Veterinary Teaching Hospital because of a 3-month history of an enlarged left mammary gland. (avma.org)
  • Percutaneous lateromedial ultrasonographic image of the enlarged left mammary gland of the filly described in Figure 1 showing an accumulation of fluid (black arrow) in the mammary gland, homogeneously hyperechoic mammary tissue (double-headed arrow), and the medial lamina (white arrows) between the 2 halves of the udder. (avma.org)
  • For instance, mammary gland adenocarcinomas in female dogs are often influenced by hormonal changes, and the risk can be reduced through spaying (ovariohysterectomy). (thevetexpert.com)
  • Arises from the mammary glands can be found in both male and female dogs. (thevetexpert.com)
  • The aim of this study was to report a clinical case of pleomorphic adenoma affecting the minor salivary gland and to discuss its characteristics, emphasizing the important role of the dentist in the correct and early diagnosis of this lesion, resulting in a more conservative treatment and better prognosis for the patient. (bvsalud.org)
  • A case of an in situ adenocarcinoma of the lacrimal gland that developed in a recurring pleomorphic adenoma is presented. (eyehospital.nl)
  • An orbital computerized tomography scan showed an inhomogeneous mass in the right lacrimal gland region without bone involvement. (eyehospital.nl)
  • Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma. (cdc.gov)
  • Head and neck cancer is cancer that starts in the lip, oral cavity (mouth), nasal cavity (inside the nose), paranasal sinuses, pharynx, larynx or parotid glands. (icd.codes)
  • In both cases, the mass was completely excised, postoperative pathology reports confirmed the diagnosis of basal cell adenoma. (e-acfs.org)
  • Kaku, T & Enjoji, M 1983, ' Extremely well-differentiated adenocarcinoma ("Adenoma malignum") of the cervix ', International Journal of Gynecological Pathology , vol. 2, no. 1, pp. 28-41. (elsevierpure.com)
  • Adenocarcinoma: This malignancy can arise from any of the tissues of the GI system, but the stomach and intestines are predisposed. (embracepetinsurance.com)
  • Platinum-based agents, in combination with mitoxantrone or vinorelbine, are also effective in controlling recurrent salivary gland malignancy. (medscape.com)
  • Using paclitaxel (Taxol), another antimicrotubule drug, alone has had moderate activity against mucoepidermoid tumors and adenocarcinomas but no effect adenoid cystic carcinoma. (medscape.com)
  • Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. (cdc.gov)
  • [ 7 ] They stressed surgical landmarks for avoiding injury to the main trunk and branches of the facial nerve and advocated complete removal of the superficial portion of the parotid gland for noninvasive lesions confined to that portion of the gland. (medscape.com)
  • However, up to 40% of lesions larger than 4cm in diameter progress to adenocarcinoma. (anatomywarehouse.com)
  • The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions. (researchgate.net)
  • Ultrasonography to visualize adrenal gland lesions and evaluate incidentally discovered adrenal masses in dogs has become more reliable with advances in imaging techniques. (biomedcentral.com)
  • The goal of our study was to investigate which ultrasound features of adrenal gland abnormalities could aid in discriminating between benign and malignant lesions. (biomedcentral.com)
  • Adrenal gland lesions (nodules and masses) commonly develop in older dogs, but surgery is indicated in only a small fraction of such cases, usually in malignant and hormone-secreting tumors [ 13 ]. (biomedcentral.com)
  • many of these benign yet floridly proliferative lesions have been mistaken for invasive adenocarcinoma. (fliphtml5.com)
  • Some lesions of the salivary glands exhibit similar clinical, histopathological and imaging aspects, which can compose a differential diagnosis of PA 6 . (bvsalud.org)
  • An estimated 700 deaths (0.4 per 100,000 for males and 0.2 per 100,000 for females) related to salivary gland tumors occur annually. (medscape.com)
  • Among these, papillomas, sebaceous gland tumors, mast cell tumors and lipomas are the most frequent in dogs. (vetinfo.com)
  • Nonmalignant disorders include cafĂ©-au-lait spots and sebaceous gland tumors. (msdmanuals.com)
  • Ceruminous gland tumors are best visualized in a clean ear using a video otoscope. (merckvetmanual.com)
  • Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. (nature.com)
  • Adenocarcinoma in dogs is a type of cancer that originates in epithelial tissues. (thevetexpert.com)
  • Adenocarcinomas can occur in different organs and tissues and are characterized by the uncontrolled growth and spread of abnormal epithelial cells. (thevetexpert.com)
  • Primary liver tumors (those that originate in the liver) are most typically bile duct adenocarcinomas, but plenty of tumors (from the GI system and spleen, for example) like to metastasize here, setting up secondary residence. (embracepetinsurance.com)
  • 20 mm in diameter and nodular in shape were often identified as cortical hyperplastic nodules or adenomas. (biomedcentral.com)
  • Fluhmann attributed tunnel clusters to the involution ofendocervical glands (crypts) that had become hyperplastic as a response to the alteredhormonal milieu of pregnancy. (fliphtml5.com)
  • Eight cases of extremely well-differentiated adenocarcinoma of the cervix were collected for clinicohistopathologic study. (elsevierpure.com)
  • The lattercan be particularly alarming if one is not aware that this type of change can occur (4).The main differential diagnosis is with extremely well-differentiated endocervicaladenocarcinoma (adenoma malignum). (fliphtml5.com)
  • Ceruminous glands are simple, coiled, tubular glands made up of an inner secretory layer of cells and an outer myoepithelial layer of cells. (wikipedia.org)
  • Tubular adenomas tend to be small, pedunculated polys composed of rounded or tubular glands. (anatomywarehouse.com)
  • cancerous tumors of the glands, such as in the ducts or lobules of the breast. (thewomenofhope.org)
  • If lesion is greater than 2.0 cm in diameter, there is increased likelihood of neoplastic etiology (adenocarcinoma, pheochromocytoma) versus benign causes. (vin.com)
  • Abnormal appearance of structural features on ultrasound images (e.g., adrenal gland lesion size, shape, laterality, and echotexture) may aid in diagnosis, but these features alone were not pathognomic. (biomedcentral.com)
  • After confirming the diagnosis of pleomorphic adenoma, we opted for enucleation of the lesion to avoid possible complications such as scar retraction and salivary fistula. (bvsalud.org)
  • A good rule of thumb is that the likelihood of an SGT being malignant is inversely proportional to the size of the gland from which it originates. (medscape.com)
  • Clinical records of 119 dogs that had undergone ultrasound adrenal gland and histological examination were reviewed. (biomedcentral.com)
  • Villous adenomas occasionally secrete large amounts of mucoid protein and/or potassium rich fluid, leading possibly to hypokalemia. (anatomywarehouse.com)
  • The common admixture of type A and B tunnelclusters, in combination with the predominantly lobulated architecture, absence ofdesmoplasia and lack of deep, widely infiltrative glands helps distinguish it fromadenoma malignum.Type B tunnel clusters Type B tunnel clusters also have a lobular architecture, but are composed ofdilated glands lined by cuboidal or flattened epithelium and filled with inspissated,mucinous secretions. (fliphtml5.com)
  • The pituitary gland is a very small organ located within the base of the brain that controls several other hormone-releasing glands. (sitstay.com)
  • The salivary glands exist as larger named "major" glands and also as many widely dispersed "minor" glands that exist throughout the upper aerodigestive submucosa (ie, palate, lip, pharynx, nasopharynx, larynx, and parapharyngeal space). (medscape.com)
  • [ 6 ] The minor salivary glands comprise 600-1000 small glands distributed throughout the upper aerodigestive tract. (medscape.com)
  • Most breast cancers are adenocarcinomas. (ucsfhealth.org)
  • Genetic predisposition can play a role in developing various cancers, including adenocarcinomas. (thevetexpert.com)