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AdenocarcinomaEpitheliumAdenocarcinoma, MucinousLung NeoplasmsEsophageal NeoplasmsPancreatic NeoplasmsBarrett EsophagusAdenocarcinoma, PapillaryCarcinoma, Pancreatic DuctalStomach NeoplasmsAdenocarcinoma, Bronchiolo-AlveolarImmunohistochemistryCardiaIn Situ HybridizationTumor Markers, BiologicalColonic NeoplasmsEsophagogastric JunctionCarcinoma in SituNeoplasm StagingGene Expression Regulation, NeoplasticPrecancerous ConditionsPrognosisIn Situ Hybridization, FluorescenceCell Line, TumorKeratin-7Carcinoma, Squamous CellEpithelium, CornealEpithelial CellsMetaplasiaEndometrial NeoplasmsIntestinal NeoplasmsNeoplasms, Multiple PrimaryImmunoenzyme TechniquesRNA, MessengerProstatic NeoplasmsTumor Cells, CulturedNeoplasm InvasivenessMammary Neoplasms, ExperimentalDuodenal NeoplasmsCarcinoma, EndometrioidCarcinoma, Signet Ring CellCecal NeoplasmsAdenocarcinoma, Clear CellEsophagusReverse Transcriptase Polymerase Chain ReactionColorectal NeoplasmsAdenomaRectal NeoplasmsGenes, rasTissue Array AnalysisSeminiferous EpitheliumNeoplasm ProteinsCommon Bile Duct NeoplasmsKeratinsIntestinal MucosaAmpulla of VaterKeratin-20DNA, NeoplasmIleal NeoplasmsMucinsPancreaticoduodenectomyDisease ProgressionNeoplasm MetastasisCell ProliferationMutationSurvival RateLymphatic MetastasisBiopsyJejunal NeoplasmsCarcinoma, Non-Small-Cell LungCarcinoma, AdenosquamousNeoplasm TransplantationRetinal Pigment EpitheliumCarcinoembryonic AntigenGene Expression ProfilingCarcinoma, Acinar CellMice, NudeRetrospective StudiesReceptor, Epidermal Growth FactorSurvival AnalysisUterine Cervical NeoplasmsTime FactorsPolymerase Chain ReactionAntigens, NeoplasmHyperplasiaCell Transformation, NeoplasticTumor Suppressor Protein p53Antineoplastic AgentsParanasal Sinus NeoplasmsGastrectomyBlotting, WesternPancreatic DuctsKaplan-Meier EstimateGastric MucosaApoptosisFatal OutcomeTreatment OutcomePancreatectomyCell DivisionGastrointestinal Neoplasms
CarcinomaCervixColumnarDysplasiaInvasiveEsophageal adenocarcinomaSurface epitheliumEndocervical adenocarcinomasEpithelial tumorBasalCervical epitheliumVaginalEsophagusMucinousEndocervixVulvarAdenomaMalignant cellsNeoplastic cellsAtypiaGoblet cellsThicknessLungPulmonaryBenignIntestinalMetastasisMitoticTissuesCancerBRONCHICellsOccurrenceCellularInvolvementDetectionPatientForms
Carcinoma20
  • Conditions of the ectocervical squamous epithelium, the endocervical glandular epithelium and the cervical stroma are systematically discussed in the context of the respective (pre)malignant lesion that they may be confused with, including low and high-grade squamous intraepithelial lesions, invasive squamous cell carcinoma, adenocarcinoma in-situ, various types of invasive adenocarcinomas, and sarcomas. (northwestern.edu)
  • Endocervical brush sampling at the time of Pap smear to detect adenocarcinoma and its precursors is necessary along with doctor/patient vigilance on abdominal symptoms associated with uterine and ovarian carcinoma. (wikipedia.org)
  • These abnormalities were classified as squamous or glandular and then further classified by the stage of dysplasia: atypical cells, mild, moderate, severe, and carcinoma. (wikipedia.org)
  • Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). (samatashkhis.com)
  • Several histological types are recognised including endocervical adenocarcinoma, endometrial adenocarcinoma and clear cell carcinoma. (eurocytology.eu)
  • The frequent coexistence of cervical adenocarcinoma with squamous carcinoma suggest that they have a common aetiology and pathogenesis. (eurocytology.eu)
  • Patient was treated by conservative excision of lesion and lumpectomy for in situ carcinoma. (medscape.com)
  • In the 4th edition of WHO classification of tumors of female reproductive organs, primary villoglandular mucinous adenocarcinoma is defined as a primary invasive glandular epithelial tumor of intestinal type and the synonyms are cloacogenic carcinoma or cloacogenic adenocarcinoma [ 1 ]. (hindawi.com)
  • It includes adenocarcinomas and squamous cell carcinoma. (imperial.ac.uk)
  • Also called carcinoma in situ (CIS). (mdwiki.org)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • Given the expression of CD44 in a wide range of cancers, the most practical application of CD44 immunostaining is its use in discriminating between urothelial transitional cell carcinoma in situ from non-neoplastic changes in the urothelium. (attogene.com)
  • Based on the type of cells affected, esophagus cancer can be divided into two major histology types, squamous cells carcinoma (affecting flat cells that line the inner side of the esophagus) and adenocarcinoma (affecting glandular cells that produce mucus and other fluids). (oncoexperts.in)
  • Patient with squamous cell carcinoma are usually thin built due to the significant weight loss, and patient with adenocarcinoma are usually obese. (oncoexperts.in)
  • Cessation of smoking reduces the risk for squamous cell carcinoma but not for adenocarcinoma. (oncoexperts.in)
  • Excessive alcohol consumption is a risk factor for SQUAMOUS CELL carcinoma but not for ADENOCARCINOMA, moreover, the risk increases with the duration and intensity of drinking. (oncoexperts.in)
  • Additionally, the patient reported uterine bleeding three years after starting tamoxifen for ductal carcinoma in situ (DCIS) of the breast. (fortuneonline.org)
  • Carcinoma que se origina en el EPITELIO de la NASOFARINGE y que incluye cuatro subtipos: queratinizante de células escamosas, no queratinizante, basaloide de células escamosas y ADENOCARCINOMA PAPILAR. (bvsalud.org)
  • A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. (bvsalud.org)
  • In most of the cases, the gallbladder cancer takes nearly 5-15 years to develop with progression of metaplsia to dysplasia, carcinoma in situ and finally to invasive cancer in that order. (asjo.in)
Cervix3
  • CIN most commonly occurs at the squamocolumnar junction of the cervix, a transitional area between the squamous epithelium of the vagina and the columnar epithelium of the endocervix. (wikipedia.org)
  • Adenocarcinomas constitute 5 - 10 % of all carcinomas arising in the cervix. (eurocytology.eu)
  • The region where there is a transition from squamous to columnar epithelium in cervix is transformation zone. (cytojournal.com)
Columnar5
  • The characteristic feature of AIS is replacement of normal columnar epithelium of the endocervical canal by neoplasic cells with hyperchromatic nuclei which is clearly shown in this section. (eurocytology.eu)
  • Of note, differentiated goblet cells retained longer telomeres than columnar lined BE epithelium. (oncotarget.com)
  • In conclusion, our studies suggest that shortened telomeres are functionally important for tumor development in a mouse model of BE and are associated with proliferating columnar epithelium in human BE. (oncotarget.com)
  • It may also occur in sites where glandular or columnar epithelium is normally present. (lookformedical.com)
  • The endocervix is lined by columnar mucinous epithelium and in continuity with vaginal mucosa, the ectocervix is lined by squamous epithelium. (cytojournal.com)
Dysplasia1
  • These tracts can be compromised in a variety of ways, including agenesis or malformation of structures, glandular dysplasia, and malignancy. (lecturio.com)
Invasive2
  • Endocervical adenocarcinoma in situ is considered to be the glandular counterpart of cervical intraepithelial neoplasia and a precursor of invasive adenocarcinoma. (eurocytology.eu)
  • Although the invasive and the in situ forms of endocervical adenocarcinoma can be recognised in histological section, a reliable distinction cannot be made from the appearance of the cells in the cervical smear. (eurocytology.eu)
Esophageal adenocarcinoma3
Surface epithelium2
Endocervical adenocarcinomas3
  • Endocervical adenocarcinomas are composed of branching and budding glands lined by neoplastic cells which in the well diffrerentiated carcinomas resemble the glandular cells lining the endocervical canal. (eurocytology.eu)
  • Poorly differentiated endocervical adenocarcinomas show a tendancy to show a solid growth formation and gland formation is rare. (eurocytology.eu)
  • A new pattern-based classification for endocervical adenocarcinomas recommends the description of patterns of invasion for human papillomavirus (HPV)-related adenocarcinomas as this is associated with differing risks of lymph node involvement. (bmj.com)
Epithelial tumor1
Basal3
  • CK5 is a type II CK (high molecular weight, 62 kDa) expressed in the basal and myoepithelial cells of various epithelia and glandular structures including the bronchi, prostate and breast. (roche.com)
  • CK5 is expressed in the basal epithelium of the lung and its overexpression is an indicator of malignant squamous differentiation in pulmonary lesions. (roche.com)
  • 1,8 The detection of CK5 in basal cells is a feature of normal and benign prostatic processes and the absence of CK5 is indicative of prostate adenocarcinoma. (roche.com)
Cervical epithelium3
  • CIN1 is the earliest form of CIN, in which the neoplastic cells are limited to the lower third of the thickness of the cervical epithelium. (iarc.fr)
  • In CIN2 and CIN3, the cervical epithelial abnormalities extend to the middle third and the upper third of the thickness of the cervical epithelium, respectively, and the cellular abnormalities become progressively more severe. (iarc.fr)
  • The majority of these changes occur at the squamocolumnar junction, or transformation zone, an area of unstable cervical epithelium that is prone to abnormal changes. (wikipedia.org)
Vaginal1
Esophagus6
  • Together, this suggests the esophagus is exposed to aldehyde stress, and that glandular esophageal cells may be vulnerable to this stress. (nature.com)
  • Little evidence supports the assumption that antisecretory agents or antireflux surgery prevents the occurrence of adenocarcinoma or leads to regression of Barrett esophagus. (medscape.com)
  • An important, as yet unanswered, question is whether abolishing acid completely with high-dose PPIs decreases the risk for adenocarcinoma of the esophagus and warrants the cost and possible adverse effects of this therapy. (medscape.com)
  • Adenocarcinoma occurs in the distal esophagus. (msdmanuals.com)
  • Diet rich in red and processed meat, saturated fats or cholesterol, increases the risk, whereas diet rich in raw fruits and vegetables, grains, fibers or carotenoids, decrease the risk of SQUAMOUS CELL AND ADENOCARCINOMA of esophagus. (oncoexperts.in)
  • Gastroesophageal reflux disease is a condition in which there is a reflux of gastric contents, including gastic acid, into the esophagus, causing changes in the epithelium leading to barret's esophagus, and adenocarcinoma. (oncoexperts.in)
Mucinous3
Endocervix1
  • Three grades of adenocarcinoma are recognised well differentiated, moderately differentiated and poorly differentiated according to how closely the morphology of the tumour resembles that of the endocervix. (eurocytology.eu)
Vulvar1
Adenoma1
Malignant cells2
  • Red, scaly plaque, microscopically characterized by the spread of malignant cells within the epithelium, occasionally with invasion of underlying dermis. (brainscape.com)
  • Among sporadic endometrial cancers, when present, the microsatellite instability is confined to the malignant cells, and is not seen in the adjacent normal epithelium. (medmuv.com)
Neoplastic cells1
  • The tumour is composed of branched and budding glands lined by mucin producing neoplastic cells which resemble the glandular cells lining the endocervical canal. (eurocytology.eu)
Atypia1
  • In some foci, there was sufficient atypia for the designation of adenocarcinoma-in-situ . (webpathology.com)
Goblet cells1
Thickness3
  • Cervical intraepithelial neoplasia (CIN) is a precancerous condition because the abnormalities are restricted to the thickness of the squamous epithelium. (iarc.fr)
  • Depending on the severity of the abnormality and the extent of involvement of the thickness of the squamous epithelium, CIN lesions are graded as CIN1, CIN2, and CIN3. (iarc.fr)
  • cellular changes involve the full thickness of the squamous epithelium. (unboundmedicine.com)
Lung1
Pulmonary1
Benign1
Intestinal1
  • This means that other fast dividing cells such as those responsible for hair growth and for replacement of the intestinal epithelium (lining) are also affected. (justia.com)
Metastasis2
Mitotic1
  • The tumor had a large proportion of mitotic cells and its resemblance to adenocarcinoma of the large intestine was striking. (hindawi.com)
Tissues1
  • Lined by stratified squamous epithelium, the tissues of the mouth are often involved when individuals have conditions affecting the GI system. (medscape.com)
Cancer1
  • The declines correlate with reductions in pathology reports and are greater for cases diagnosed at in situ and localized stage, triggering concerns about potential poor cancer outcomes in the coming years, especially in Asians/Pacific Islanders. (cdc.gov)
BRONCHI1
Cells3
  • In addition, the normal systematic arrangement of the different layers of the epithelium is lost (this is called a loss of polarity) as the cells become cancerous. (iarc.fr)
  • A malignant tumor composed of cells showing differentiation toward sebaceous epithelium. (nih.gov)
  • AGUS stands for atypical glandular cells of undetermined significance. (com.ng)
Occurrence1
  • Recent NIOSH research has identified geochemical markers that correlate with in situ reportable dynamic event occurrence, although the causes behind this correlative relationship remain unclear. (cdc.gov)
Cellular1
Involvement1
  • Germ cell neoplasia-in-situ with pagetoid involvement of rete testis was seen. (webpathology.com)
Detection2
  • Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "Anti-Cytokeratin 5/6 (D5/16B4) Mouse Monoclonal Primary Antibody is intended for laboratory use in the qualitative immunohistochemical detection of cytokeratin 5 by light microscopy in sections of formalin-fixed, paraffin-embedded tissue stained on a BenchMark IHC/ISH instrument. (roche.com)
  • Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Background Information", "Value": "Anti-Cytokeratin 5/6 (D5/16B4) Mouse Monoclonal Primary Antibody (anti-Cytokeratin 5/6 (D5/16B4) antibody) is a mouse monoclonal antibody raised for the detection of cytokeratin (CK) 5. (roche.com)
Patient1
  • Until recently, the history and counsel the patient about mal epithelium (Ghaem-Maghami et standard follow-up regime in most the need for longer-term follow-up, al. (who.int)
Forms1
  • Clinically, the most significant histological forms are malignant neoplasms developing from the integumentary squamous epithelium of the external genital organs. (med-blog.com)