• SOX9 was upregulated at both the mRNA and protein level in the majority of lung adenocarcinomas compared with normal tissue. (bmj.com)
  • Here we report a large-scale project to characterize copy-number alterations in primary lung adenocarcinomas. (broadinstitute.org)
  • On the basis of genomic and functional analyses, we identify NKX2-1 (NK2 homeobox 1, also called TITF1), which lies in the minimal 14q13.3 amplification interval and encodes a lineage-specific transcription factor, as a novel candidate proto-oncogene involved in a significant fraction of lung adenocarcinomas. (broadinstitute.org)
  • Here we report a large, training-testing, multi-site, blinded validation study to characterize the performance of several prognostic models based on gene expression for 442 lung adenocarcinomas. (nature.com)
  • This study also provides the largest available set of microarray data with extensive pathological and clinical annotation for lung adenocarcinomas. (nature.com)
  • Adenocarcinoma usually develops on the outer boundaries of the lungs and is more commonly found in women than in men. (medlineplus.gov)
  • An adenocarcinoma that forms in the lining of the lungs, causing lung cancer , may metastasize itself to the cells in the person's bones. (wisegeek.com)
  • Similar immunohistochemical staining (CDX2+, CK7+ and β-catenin-) with urachal adenocarcinoma. (auanet.org)
  • Those arising from the urachus ( urachal adenocarcinoma , ~1/3), and those arising from the bladder itself (~2/3) (image A) . (auanet.org)
  • Other morphologies include signet ring cell , which can diffusely spread into the bladder, and adenocarcinoma, not otherwise classifiable , or a mixed of these different patterns. (auanet.org)
  • bcl-2 and p53 in endometrial adenocarcinoma. (nih.gov)
  • Common symptoms and signs of gastroesophageal adenocarcinoma include difficulty or pain with swallowing and unintentional weight loss . (medicinenet.com)
  • There is no known way to prevent gastroesophageal adenocarcinoma, but it is possible to minimize certain risk factors. (medicinenet.com)
  • The prognosis for cats with adenocarcinoma of the gastrointestinal tract is usually poor. (petmd.com)
  • Sometimes adenomas transform into adenocarcinomas, but most do not. (wikipedia.org)
  • The gastroenterologist uses a colonoscopy to find and remove these adenomas and polyps to prevent them from continuing to acquire genetic changes that will lead to an invasive adenocarcinoma. (wikipedia.org)
  • Adenocarcinoma of the duodenum may arise from duodenal polyps observed in familial polyposis or Gardener's syndrome or be associated with celiac disease [ 3 , 4 ]. (hindawi.com)
  • Although local recurrence on the wound after hemorrhoidectomy is not frequently seen, we encountered two patients with adenocarcinoma on the hemorrhoidectomy wound after hemorrhoidectomy. (springer.com)