• Some think that, at the origin of life on Earth, the first adenine was formed by the polymerizing of five hydrogen cyanide (HCN) molecules. (newworldencyclopedia.org)
  • Recent studies support an earlier suggestion that, if adenine was formed prebiotically on the primitive earth, eutectic freezing of hydrogen cyanide solutions is likely to have been important. (springer.com)
  • Here we revisit the suggestion that the synthesis of adenine may have involved the photochemical conversion of the tetramer of hydrogen cyanide in eutectic solution to 4-amino-5-cyano-imidazole. (springer.com)
  • Oro, J.: 1961a, Mechanisms of Synthesis of Adenine from Hydrogen Cyanide Under Possible Primitive Earth Conditions, Nature 191 , 1193-1194. (springer.com)
  • However it is no longer considered a true vitamin (see Vitamin B). Some think that, at the origin of life on Earth, the first adenine was formed by the polymerizing of 5 hydrogen cyanide (HCN) molecules. (wikibooks.org)
  • As critical as it is, though, adenine is simply a pentamer of hydrogen cyanide. (umsystem.edu)
  • When the adenine dimer is clustered with several water molecules, we observe a nanosecond lifetime from excimer states in π-stacked clusters . (rsc.org)
  • In the present study, we determined the monocyte adhesion in the adenine-induced uremic rats in vivo and effects of AST-120 on the adhesion molecules. (hindawi.com)
  • The mechanisms of photoinduced reactions of adenine with water molecules in hydrogen-bonded adenine-water complexes were investigated with ab initio wave-function-based electronic-structure calculations. (rsc.org)
  • These reactions, which involve the reactivity of adenine with hydrogen-bonded water molecules, compete with the well-established intrinsic excited-state deactivation mechanisms of adenine via ring-puckering or ring-opening conical intersections. (rsc.org)
  • Found in both DNA and RNA, adenine is one of the most important biological molecules. (umsystem.edu)
  • However, two B vitamins, niacin and riboflavin , bind with adenine to form the essential cofactors NAD and FAD respectively. (wikipedia.org)
  • A lack of functional enzyme impairs the conversion of adenine to AMP. (medlineplus.gov)
  • This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). (antikoerper-online.de)
  • Liu, Y. In-Situ Self-Assembly of Zinc/Adenine Hybrid Nanomaterials for Enzyme Immobilization. (mdpi.com)
  • Biological systems tend to conserve energy, so usually adenine is obtained through the diet, the body degrading nucleic acid chains to obtain individual bases and reconstructing them through mitosis . (newworldencyclopedia.org)
  • Adenine nucleotide translocase (ANT) was found to be the only protein in the mitochondrial membranes exhibiting a detectable age-associated increase in carbonyls. (pnas.org)
  • Results of the present study indicate that age-related increase in molecular oxidative damage to mitochondrial membrane proteins is indeed highly selective, primarily involving adenine nucleotide translocase (ANT), with severe loss of its functional activity. (pnas.org)
  • Western Blot: Adenine Nucleotide Translocase 1 Antibody [NBP1-- RPMI 8226 cell lysate, concentration 0.2-1 ug/ml. (novusbio.com)
  • A major goal of origin-of-life studies is to determine potential mechanisms for the prebiotic synthesis of nucleic acid bases, such as adenine. (acs.org)
  • Rainer Glaser of the University of Missouri, Columbia, and coworkers now have used a theoretical model of gas-phase chemistry to predict mechanisms for adenine production in space ( Astrobiology 2007 , 7, 455). (acs.org)