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  • among
  • DNA adenine methyltransferase (Dam) is widespread and conserved among the γ-proteobacteria. (osti.gov)
  • nucleotides
  • Therefore, either the cells are making their own nucleotides, or their primary source of adenine must be from the FBS that we conventionally add to the D-MEM. (bio.net)
  • The metabolism of acid soluble adenine nucleotides in heat-synchronized Tetrahymena pyriformis GL has been studied. (springer.com)
  • In cells induced to divide synchronously through heat treatment (cyclic pulses of 34 °C for 30 min alternating with a 30 min recovery period at 28 °C) variations occurred in the levels of adenine nucleotides when samples of cells were analysed at the end of the last thermal period and at various times preceding the first synchronous cell division. (springer.com)
  • The specific activities of the adenine nucleotides were found to be significantly higher during a pulse label period performed at the end of the last thermal period than at any time during the subsequent synchronous division cycle. (springer.com)
  • But a potentially less expensive and even simpler approach, according to the NIST, NRL and UMD team, might be to use a string of adenine nucleotides as an anchor. (biologynews.net)
  • Of the four nucleotides that comprise DNA molecules, adenine, turns out to have a particularly high affinity for gold. (biologynews.net)
  • hydrogen bonds
  • In all cases these quartets display four cyclic hydrogen bonds only, which extend from the N(6)H 2 groups of adenine, which function as the donors, yet use different acceptor sites, namely, N1 (A 4 -N1), N3 (A 4 -N3), and N7 (A 4 -N7). (springer.com)
  • Astrobiology
  • Rainer Glaser of the University of Missouri, Columbia, and coworkers now have used a theoretical model of gas-phase chemistry to predict mechanisms for adenine production in space ( Astrobiology 2007 , 7, 455). (acs.org)
  • Mice
  • Both adenine-fed wild-type (WT) and Jα18KO mice exhibited renal dysfunction, but adenine-fed Jα18KO mice presented higher expression of kidney injury molecule-1 (KIM-1), tumor necrosis factor (TNF)-α and type I collagen. (springer.com)
  • To analyze the role of activated iNKT cells in our model, we administered αGalCer in WT mice during adenine ingestion. (springer.com)
  • However, this improvement in renal function was not observed in IFN-γKO mice after αGalCer treatment and adenine feeding, illustrating that this cytokine plays a role in our model. (springer.com)
  • We investigated the anti-allergic effect of adenine on IgE-mediated mast cell activation in vitro and passive cutaneous anaphylaxis (PCA) in mice. (sigmaaldrich.com)
  • Intraperitoneal injection of adenine to IgE-sensitized mice attenuated IgE-mediated PCA reaction in a dose dependent manner, resulting in a median effective concentration of 4.21 mg/kg. (sigmaaldrich.com)
  • From this result, we report for the first time that adenine inhibits PCA in mice and allergic reaction by inhibiting FcɛRI-mediated signaling events in mast cells. (sigmaaldrich.com)
  • complexes
  • First, we examine the empty quartets and how they interact with alkali cations and halide anions with formation of adenine quartet-ion complexes. (springer.com)
  • bases
  • Single-strand DNA can be anchored to a gold substrate for use in biodetectors by attaching a tail of adenine bases. (biologynews.net)
  • Renal
  • 6 ) demonstrated that an excessive intake of adenine would lead to renal injury. (springer.com)
  • Adenine is produced endogenously but its long-term ingestion results in 2,8-dihydrox-yadenine precipitation inside the renal tubules, leading to the formation of kidney stones, with extensive tubular dilation, inflammation, necrosis and fibrosis. (springer.com)
  • molecule
  • As a result, adenine is converted to another molecule called 2,8-dihydroxyadenine (2,8-DHA). (nih.gov)
  • Formation
  • This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). (nih.gov)
  • If adenine formation occurs throughout space, 'life everywhere might have started out pretty much the same way,' he adds. (acs.org)
  • serum
  • Does anyone do these kind of assays, and do you typically remove the serum when you load the cells with hot adenine? (bio.net)
  • pairs
  • Quartet structures of adenines can also be part of polymeric ribbons of adenine pairs [ 20 , 21 ], but the latter will not be considered further here. (springer.com)
  • Structures
  • We have investigated the structures and stabilities of four different adenine quartets with alkali and halide ions in the gas phase and in water, using dispersion-corrected density functional theory at the BLYP-D/TZ2P level. (springer.com)
  • found
  • 14 ], A 4 -N7 was found to interact with a Na + ion, which prompted us to look into the possibility of the interaction of adenine quartets with anions. (springer.com)