• Decarboxylative condensations for a single-chain elongation are facilitated by β-ketosynthase (KS), acyl transferase (AT), and acyl carrier protein (ACP). (wikipedia.org)
  • What happens if you lack the proteins to transport Acyl-Coa into the matrix? (flashcardmachine.com)
  • Essential in the yeast FAS catalytic cycle is the acyl carrier protein (ACP) that actively shuttles substrates, biosynthetic intermediates, and products from one active site to another. (bvsalud.org)
  • E. faecalis has two acyl carrier proteins (ACPs), AcpA (EfAcpA), which is essential for de novo fatty acid synthesis (FAS), and EfAcpB, which plays an auxiliary role in the incorporation of exogenous fatty acids. (bvsalud.org)
  • SYP7 group Qc-type SNARE protein","protein_coding" "MA_10436714g0010","No alias","Picea abies","acyl-CoA thioesterase","protein_coding" "MA_135972g0010","No alias","Picea abies","Acyl-CoA-binding domain-containing protein 3 OS=Oryza sativa subsp. (ntu.edu.sg)
  • Starting from the N-terminus, these units include β-ketoacyl synthase (KS), acetyl/malonyl transacylase (AT/MT), β-hydroxyacyl dehydratase (DH), enoyl reductase (ER), β-ketoacyl reductase (KR), acyl carrier protein (ACP), and thioesterase (TE). (aging-us.com)
  • Acyl-acyl carrier protein thioesterases (acyl-ACP TEs) catalyze the hydrolysis of the thioester bond that links the acyl chain to the sulfhydryl group of the phosphopantetheine prosthetic group of ACP. (iastate.edu)
  • SCO3285 putative large glycine/alanine rich protein 3628804:3634122 reverse MW:187287 0014. (kitasato-u.ac.jp)
  • SCO3869 putative WD-40 repeat protein 4252856:4257886 forward MW:177236 0015. (kitasato-u.ac.jp)
  • SCO2383 putative secreted protein 2552256:2556893 forward MW:161489 0017. (kitasato-u.ac.jp)
  • SCO4508 putative cell division-related protein 4928990:4933567 reverse MW:163295 0018. (kitasato-u.ac.jp)
  • SCO7015 putative membrane protein. (kitasato-u.ac.jp)
  • SCO5710 putative large Pro/Ala/Gly-rich protein 6221737:6225837 forward MW:141045 0022. (kitasato-u.ac.jp)
  • SCO2450 putative protein kinase (regulator) 2632795:2636844 forward MW:145674 0024. (kitasato-u.ac.jp)
  • SCO2259 putative multi-domain regulatory protein. (kitasato-u.ac.jp)
  • SCO6219 putative ATP/GTP binding protein 6832135:6835920 forward MW:133958 0029. (kitasato-u.ac.jp)
  • SCO4263 putative transcriptional regulatory protein 4675582:4679337 forward MW:132620 0030. (kitasato-u.ac.jp)
  • SCO7037 putative secreted protein 7826610:7830005 forward MW:118466 0036. (kitasato-u.ac.jp)
  • SCO2672 putative membrane protein 2908366:2911707 forward MW:112750 0039. (kitasato-u.ac.jp)
  • SCO0369 putative secreted protein 373998:377255 reverse MW:117277 0043. (kitasato-u.ac.jp)
  • SCO0372 putative secreted protein 383578:386592 reverse MW:107736 0050. (kitasato-u.ac.jp)
  • SCO0505 putative multi-domain protein (fragment) 539123:542131 forward MW:108602 0051. (kitasato-u.ac.jp)
  • SCO4874 putative integral membrane protein 5303718:5306603 forward MW:99145 0060. (kitasato-u.ac.jp)
  • protein_coding" "Cz12g19130.t1","No alias","Chromochloris zofingiensis","Clp protease proteolytic subunit /Translocation-enhancing protein TepA [Interproscan]. (ntu.edu.sg)
  • protein_coding" "AAC73960","hcp","Escherichia coli","hybrid-cluster [4Fe-2S-2O] subunit of anaerobic terminal reductases [Ensembl]. (ntu.edu.sg)
  • subunit alpha of MPP mitochondrial signal peptidase heterodimer","protein_coding" "Zm00001e017599_P001","No alias","Zea mays","Protein disulfide isomerase-like 2-2 OS=Oryza sativa subsp. (ntu.edu.sg)
  • Peptide epimerase-dehydratase complex responsible for biosynthesis of the linaridin class ribosomal peptides. (hokudai.ac.jp)
  • Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells. (porphyria.org)
  • Functional annotation resulted in the identification of almost all genes involved in diverse lipid-metabolic pathways, including the novel fatty acid desaturase/epoxygenase, diacylglycerol acyltransferase 1 and 2, and phospholipid:diacylglycerol acyltransferases. (researchsquare.com)
  • protein_coding" "Cz05g31090.t1","No alias","Chromochloris zofingiensis","Pterin 4 alpha carbinolamine dehydratase [Interproscan]. (ntu.edu.sg)
  • protein_coding" "Cz06g21140.t1","No alias","Chromochloris zofingiensis","Aldose 1-/Glucose-6-phosphate 1-epimerase [Interproscan]. (ntu.edu.sg)
  • protein_coding" "Cz10g14210.t1","No alias","Chromochloris zofingiensis","DEAD/DEAH box helicase domain [Interproscan]. (ntu.edu.sg)
  • Ribosomal protein S20 [Interproscan]. (ntu.edu.sg)
  • Bor protein [Interproscan]. (ntu.edu.sg)
  • Protein of unknown function (DUF1158) [Interproscan]. (ntu.edu.sg)
  • Protein of unknown function (DUF2526) [Interproscan]. (ntu.edu.sg)
  • Ribosomal protein L35 [Interproscan]. (ntu.edu.sg)
  • Protein of unknown function (DUF441) [Interproscan]. (ntu.edu.sg)
  • LysR substrate binding domain, Bacterial regulatory helix-turn-helix protein [Interproscan]. (ntu.edu.sg)
  • YebO-like protein [Interproscan]. (ntu.edu.sg)
  • Protein of unknown function (DUF2511) [Interproscan]. (ntu.edu.sg)
  • Copper resistance protein D [Interproscan]. (ntu.edu.sg)
  • Protein of unknown function (DUF520) [Interproscan]. (ntu.edu.sg)
  • There are many possible applications for these genes: you could try to recreate essential gene pathways in-vitro, or purify the proteins for functional studies, or create a synthetic MoClo-compatible Bacillus subtilis genome using these genes and the sgRNAs available from the Bacillus Genetic Stock Center. (freegenes.org)
  • The biosynthetic gene clusters of these linaridins lack obvious candidate genes for the dehydratase and epimerase required to introduce dehydrobutyrine and D-amino acid residues, respectively. (hokudai.ac.jp)
  • However, we previously demonstrated that the grisemycin (grm) cluster contained cryptic dehydratase and epimerase genes by heterologous expression of this biosynthetic gene cluster in Streptomyces lividans and proposed that two genes (grmH and grmL) with unknown functions catalyze dehydration and epimerization reactions. (hokudai.ac.jp)
  • So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. (wikidoc.org)
  • Nasu, S., Wicks, F.D. and Gholson, R.K. L -Aspartate oxidase, a newly discovered enzyme of Escherichia coli , is the B protein of quinolinate synthetase. (enzyme-database.org)
  • protein_coding" "AAC74319","hns","Escherichia coli","global DNA-binding transcriptional dual regulator H-NS [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74323","adhE","Escherichia coli","fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase [Ensembl]. (ntu.edu.sg)
  • G-6-PO 4 can also be produced via pyruvate from protein catabolism of glucogenic amino acids ( Table 17.1 ) or breakdown of glycerol from lipids (gluconeogenesis). (oncohemakey.com)
  • protein_coding" "AAC74185","ptsG","Escherichia coli","fused glucose-specific PTS enzymes: IIB component/IIC component [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74850","yeaD","Escherichia coli","D-hexose-6-phosphate epimerase-like protein [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74888","manY","Escherichia coli","mannose-specific enzyme IIC component of PTS [Ensembl]. (ntu.edu.sg)
  • The codon table used was the FreqB table from " Design Parameters to Control Synthetic Gene Expression in Escherichia coli ", which was used because it was shown to express proteins well and was recommended to us by JCVI. (freegenes.org)
  • The Escherichia coli Protein YfeX Functions as a Porphyrinogen Oxidase, Not a Heme Dechelatase. (porphyria.org)
  • Fatty acids enter the mitochondria via the carnitine transport cycle (medium chain fatty acids enter independently of carnitine) into the β-oxidation spiral in which fatty acids, via a series of enzymes, produce acetyl-CoA and electron carriers. (oncohemakey.com)
  • fatty acid binding protein 4 [Source:H. (gsea-msigdb.org)
  • Although lipids are a distinct class of biomolecules, we shall see that they often occur combined, either covalently or through weak bonds, with members of other classes of bio-molecules to yield hybrid molecules such as glycolipids , which contain both carbohydrate and lipid groups, "and lipoproteins , which contain both lipids and proteins. (medmuv.com)
  • Figure 17.1 illustrates the metabolic processes involved in the overall metabolism of carbohydrates, fats and protein including the catabolic processes to produce energy and urea (the product of the detoxification of the nitrogen moiety of amino acids) and anabolic processes to form tissue protein and energy stores, glycogen and lipids. (oncohemakey.com)
  • Further, the "HomoloGene" function of the NCBI was used to conduct conserved functional domain analysis of the FASN protein in different species. (aging-us.com)
  • Commonly the term metabolism defines the breakdown of food and how its components (carbohydrates, fats and proteins) are transformed into energy via a sequence of chemical reactions (metabolic pathways) which are controlled by large numbers of different enzymes. (oncohemakey.com)
  • Additionally, several features (e.g., gene expression, survival prognosis, genetic alteration, DNA methylation, protein phosphorylation, immune cells, or relevant cellular pathways) were gathered to evaluate the regulatory mechanism of FASN in the tumorigenesis of cancers. (aging-us.com)
  • SCO6428 hypothetical protein 7097567:7104511 reverse MW:242150 0007. (kitasato-u.ac.jp)
  • SCO6220 hypothetical protein SC2H4.02 6836057:6842608 forward MW:233391 0011. (kitasato-u.ac.jp)
  • SCO6626 hypothetical protein SC1F2.23 7348537:7353210 forward MW:169206 0016. (kitasato-u.ac.jp)
  • SCO6432 hypothetical protein 7111866:7116089 forward MW:148817 0021. (kitasato-u.ac.jp)
  • SCO6348 hypothetical protein SC3A7.16c 7006807:7010892 reverse MW:144986 0023. (kitasato-u.ac.jp)
  • SCO2975 hypothetical protein SCE50.03 3236736:3240773 forward MW:135331 0025. (kitasato-u.ac.jp)
  • SCO6572 hypothetical protein SC3F9.07 7275867:7279583 forward MW:133432 0031. (kitasato-u.ac.jp)
  • SCO6431 hypothetical protein 7108264:7111779 forward MW:126560 0034. (kitasato-u.ac.jp)
  • SCO0072 hypothetical protein 60740:64093 reverse MW:119295 0038. (kitasato-u.ac.jp)
  • SCO4250 hypothetical protein SCD8A.23 4656900:4660235 forward MW:103694 0040. (kitasato-u.ac.jp)
  • SCO5271 hypothetical protein 5731309:5734599 forward MW:117582 0041. (kitasato-u.ac.jp)
  • SCO6994 hypothetical protein SC8F11.20c. 7762852:7766112 reverse MW:113220 0042. (kitasato-u.ac.jp)
  • SCO5717 hypothetical protein SC3C3.03c 6233478:6236729 reverse MW:112052 0044. (kitasato-u.ac.jp)
  • SCO0069 hypothetical protein 56225:59383 forward MW:114192 0046. (kitasato-u.ac.jp)
  • SCO0335 hypothetical protein 336333:339467 forward MW:111223 0047. (kitasato-u.ac.jp)
  • SCO4331 hypothetical protein SCD12A.14 4742776:4745904 forward MW:110720 0048. (kitasato-u.ac.jp)
  • SCO5842 hypothetical protein SC9B10.09 6394529:6397648 forward MW:107570 0049. (kitasato-u.ac.jp)
  • SCO4548 hypothetical protein 4964060:4967068 forward MW:105802 0052. (kitasato-u.ac.jp)
  • SCO0305 hypothetical protein 299213:302092 forward MW:106033 0061. (kitasato-u.ac.jp)
  • SCO4254 hypothetical protein SCD8A.27 4663248:4666118 forward MW:101164 0062. (kitasato-u.ac.jp)
  • SCO2116 hypothetical protein 2273596:2276427 forward MW:100732 0063. (kitasato-u.ac.jp)
  • The modification domains that contribute to structural variations are dehydratase (DH), enoylreductase (ER), and β-ketoreductase (KR). (wikipedia.org)
  • The structural information suggests that each FAS functional unit could accommodate exogenous proteins to incorporate various enzymatic activities, and we show proof-of-concept experiments where ectopic proteins are used to modulate FAS product profiles. (bvsalud.org)
  • Zinc mesoporphyrin induces rapid proteasome-mediated degradation of hepatitis C non-structural 5A protein in human hepatoma cells. (porphyria.org)
  • Li T, Bonkovsky HL, Guo J-T. Structural analysis of heme proteins: implications for design and prediction. (porphyria.org)
  • The human FASN protein is composed of six catalytic units. (aging-us.com)
  • Not merely abnormal fat burning capacity of HS continues to be reported in DKD (14), but also variations within a gene encoding another HS-O sulfotransferase (gene, also called (growth-arrest-specific proteins 3), encodes a glycoprotein whose mutations trigger neuropathy-related illnesses and whose features stay incompletely known (16). (tam-receptor.com)
  • These bacteria can endure extremes of temperature and this may be due to the high thermostability of its proteins. (bvsalud.org)
  • In this study, we confirmed that both GrmH and GrmL, which were shown to constitute a protein complex by a co-purification experiment, were required to catalyze the dehydration, epimerization, and proteolytic cleavage of a precursor peptide GrmA by in vivo experiments. (hokudai.ac.jp)
  • N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. (hokudai.ac.jp)
  • Electron carriers (FADH 2 and NAD) enter the electron transfer chain to produce ATP. (oncohemakey.com)
  • Figure 17.1 Summary of metabolism of carbohydrates, fats and proteins. (oncohemakey.com)