• Based on our results we provide a general guideline to the optimal synthesis method of a given CoA-thioester in respect to its functional group(s) and the commercial availability of the precursor molecule. (mdpi.com)
  • These include glyoxysomal malate dehydrogenase (gMDH), glyoxysomal citrate synthase (gCS), and acyl-CoA oxidase and thiolase in plants, as well as alkyl-dihydroxyacetone-phosphate (DHAP) synthase, phytanoyl-CoA hydroxylase and thiolase in mammals. (springer.com)
  • Another destination of acetyl-CoA is the production of ketone bodies in the liver that are transported to tissues like the heart and brain for energy production during starvation. (biomedcentral.com)
  • Fibroblast enzyme assay by UV-HPLC detection failed to clearly discriminate between some clinically presenting VLCADD patient cell lines and cell lines from some simple heterozygotes. (mdpi.com)
  • The transcriptional response included differential expression of genes encoding stress response components such as the antioxidant network and molecular chaperones, cellular components such as core photosynthesis machinery, integral light-harvesting protein complexes and enzymes such as fatty acid desaturases. (frontiersin.org)
  • Differential expression of genes encoding glyoxylate cycle enzymes were also found, representing the first report of this in Symbiodinium . (frontiersin.org)
  • The purple protein then dissociates and carries electrons to an membrane-bound enzyme that transfers electrons to ubiquinol (QH 2 ). (blogspot.com)
  • Alterations in membrane phospholipid composition are known to influence a diverse range of cellular functions, from the properties of membrane-bound enzymes to cell growth ( 28 , 41 ). (physiology.org)
  • In the liver, ethanol is metabolized to acetaldehyde by two systems: the cytosolic, largely uninducible, aldehyde dehydrogenase (ADH) and the ethanol inducible microsomal cytochrome P4502E1 [ 5 , 6 ]. (hindawi.com)
  • section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes. (uniprot.org)
  • Almost all of these mutations change single protein building blocks (amino acids) in the SCAD enzyme. (nih.gov)
  • The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. (genecards.org)
  • 2011 ). In fewer matrix enzymes, the type 2 peroxisomal targeting signal (PTS2) with the consensus sequence (R/K)-(L/I/V)-X 5 -(H/Q)-(L/A) is located in the N-terminal 30 to 50 amino acids of the pre-protein (Flynn et al. (springer.com)
  • Babies with galactosemia lack the enzyme that converts galactose (one of two sugars found in lactose) into glucose , the major source of energy for the body's cells. (kidshealth.org)
  • The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of. (patents.com)
  • Some embodiments are directed to a process for the treatment of organic waste which couples in situ biostimulation to produce hydrolytic enzymes and hydrolysis. (patents.com)
  • The majority of these enzymes are imported in their mature form targeted by a C-terminal (S/A/P/C)-(K/R/S/N)-(L/M/I) tripeptide designated as peroxisomal targeting signal 1 (PTS1) (Lingner et al. (springer.com)