• The growing fatty acid chain is carried between these active sites while attached covalently to the phosphopantetheine prosthetic group of an acyl carrier protein (ACP), and is released by the action of a thioesterase (TE) upon reaching a carbon chain length of 16 (palmitic acid). (wikipedia.org)
  • By definition, essential proteins of a cellular organism are necessary to live and replicate, and are therefore attractive targets for antimicrobial treatments. (biomedcentral.com)
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)
  • Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure. (supfam.org)
  • These are acyl CoAs where the group acylated to the coenzyme A moiety is a long aliphatic chain of 13 to 21 carbon atoms. (ymdb.ca)
  • In epididymal white adipose tissue (eWAT) of PDE3B KO mice on a SvJ129 background, cAMP/protein kinase A (PKA) and AMP-activated protein kinase (AMPK) signaling pathways are activated, resulting in "browning" phenotype, with a smaller increases in body weight under high-fat diet, smaller fat deposits, increased β-oxidation of fatty acids (FAO) and oxygen consumption. (antibody-antibodies.com)
  • As constituents of neutral and polar lipids, as side chains in some coenzymes and secondary metabolites, as covalent attachments to distinct eucaryotic proteins, and as parts of eucaryotic second-messenger molecules, they fulfill central roles not only in biological energy storage or in the integrity and dynamics of biological membranes but also in the control of cellular metabolism and cell physiology. (asm.org)