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  • fatty acid
  • The acyl carrier protein (ACP) is an important component in both fatty acid and polyketide biosynthesis with the growing chain bound during synthesis as a thiol ester at the distal thiol of a 4'-phosphopantetheine moiety. (wikipedia.org)
  • The fatty acid synthetic pathway is the principal route for the production of membrane phospholipid acyl chains in bacterial and plants. (wikipedia.org)
  • The C16 acyl-CoA product acts as a substrate for the synthesis of meromycolic acid by FAS-II, whereas the C26 fatty acid constitutes the alpha branch of the final mycolic acid. (wikipedia.org)
  • FA (fatty acid) synthesis represents a central, conserved process by which acyl chains are produced for utilization in a number of end-products such as biological membranes. (biochemj.org)
  • enzymes
  • This family of enzymes is found only in the plastids of higher plant cells, unlike other desaturases such as acyl-lipid desaturases and acyl-CoA desaturases. (wikipedia.org)
  • synthases
  • Christensen QH, Grove TL, Booker SJ, Greenberg EP (2013) A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases. (springer.com)
  • enzyme
  • Carriers have low enzyme levels compared to their family population ("normal" levels vary from family to family) but even low enzyme levels are adequate to process the body's sulfatide. (wikipedia.org)
  • pathway
  • a) the ABC transporter that allows the fatty acid transport across the peroxisomal membrane, b) enzymes carrying out the beta-oxidation pathway ACOX1, D-PBE, ACAA1 and SCPX, c) CROT, which transfers the carnitine to an acyl not completely oxidized, d) the thioesterases PTE1, PTE2, PTE2a and PTE2b, that regulates the acyl-CoA esterification and control the fatty acid shorting during the beta-oxidation. (216.92.14)
  • Gene
  • When a couple where one partner or both are sufferers or carriers of a single-gene disorder wish to have a child, they can do so through in vitro fertilization, which means they can then have a preimplantation genetic diagnosis to check whether the embryo has the genetic disorder. (wikipedia.org)
  • An affected person usually has unaffected parents who each carry a single copy of the mutated gene (and are referred to as carriers). (wikipedia.org)
  • high
  • This led to high levels of fatty acyl-CoA being present in the liver, which shows that a diseased liver cannot regulate the amount of fatty acyl-CoA that is present versus a normal, healthy liver. (wikipedia.org)
  • Domain
  • The ACB domain consists of four alpha-helices arranged in a bowl shape with a highly exposed acyl-CoA-binding site. (wikipedia.org)
  • function
  • Based on operon analyses, ARC3 homologues may function either as secondary carriers or as primary active transporters, similarly to the ArsB and ArsAB families. (wikipedia.org)