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  • PMID
  • This domain can be found in acyl transferases such as bacterial malonyl-CoA ACP transacylase (FabD) and the homologous domain from eukaryotic fatty acid synthase [ PMID: 12575934 ]. (ebi.ac.uk)
  • This domain is also found in lysophospholipases such as cytosolic phospholipase A2 (which has additional structural features) [ PMID: 10319815 ], and in patatin proteins, which are plant glycoproteins that act as non-specific lipid acyl hydrolases [ PMID: 12779324 ]. (ebi.ac.uk)
  • Acyl-CoA-binding protein (ACBP) is a small (10 Kd) protein that binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters [ PMID: 1454809 ]. (ebi.ac.uk)
  • The ligand is bound through specific interactions with residues on the protein, most notably several conserved positive charges that interact with the phosphate group on the adenosine-3'phosphate moiety, and the acyl chain is sandwiched between the hydrophobic surfaces of CoA and the protein [ PMID: 11491287 ]. (ebi.ac.uk)
  • carrier
  • 4'-Phosphopantetheine is an essential prosthetic group of several acyl carrier proteins involved in pathways of primary and secondary metabolism including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, and peptidyl carrier proteins (PCP) and aryl carrier proteins (ArCP) of nonribosomal peptide synthetases (NRPS). (wikipedia.org)
  • The structures of a number of acyl carrier proteins have been solved using various NMR and crystallography techniques. (wikipedia.org)
  • gene
  • The peroxisome proliferator (PP) response element (PPRE) upstream of the human acyl CoA oxidase gene is inactive in a sample human population: significance for species differences in response to PPs. (thefreedictionary.com)
  • cite the finding of an inactive PP response element upstream of the acyl CoA oxidase gene in a sample human population (15) as additional evidence for why humans may be less responsive than rodents to PPs. (thefreedictionary.com)
  • Serum
  • This highly-potent serum helps reduce the look of deep wrinkles and creases using Perricone MD's proprietary Acyl-Glutathione, the body's "master antioxidant" that depletes over time. (sephora.com)
  • The Acyl-Glutathione Eye Lid Serum helps to replenish the skin's glutathione levels which will address multiple eye concerns. (skinstore.com)
  • The new Acyl-Glutathione Eye Lid Serum has been proven effective for firming the upper eyelid area while helping to reduce dark circles and redness around the eye area. (skinstore.com)
  • If you are searching for a treatment product for the face that will help to address deep lines and wrinkles, try using the regular Acyl-Glutathione, then apply the serum to the eye area for optimum results. (skinstore.com)
  • MCAD
  • MCAD can bind to a rather broad range of chain-lengths in the acyl-CoA substrate, however studies show that its specificity tends to target octanoyl-CoA (C8-CoA). (wikipedia.org)
  • molecule
  • There are a total of 4 active sites within the tetramer, each of which contains a single FAD molecule and an acyl-CoA substrate binding site. (wikipedia.org)
  • substituent
  • The tetrahedral intermediate of an acyl compound contains a substituent attached to the central carbon that can act as a leaving group. (wikipedia.org)
  • chain
  • Legend: Fatty-acyl-chain FTIR spectra bands assignation according to curve-fitting methods and cross-validated by molecular structure modeling. (springer.com)
  • Finally, ν as (CH 2 ) groups raise different absorption bands according to their position in the fatty acyl chain, at primer position (close to ester or amide bond), inner or terminal positions. (springer.com)
  • Long-chain acyl-CoAs also regulate opening of ATP-sensitive potassium channels and activation of Calcium ATPases, thereby regulating insulin secretion. (wikipedia.org)