• Intravenous aciclovir is effective to treat severe medical conditions caused by different species of the herpes virus family, including severe localized infections of herpes virus, severe genital herpes, chickenpox and herpesviral encephalitis. (wikipedia.org)
  • Classified as a Category B drug, the CDC and others have declared that during severe recurrent or first episodes of genital herpes, aciclovir may be used. (wikipedia.org)
  • Acyclovir is also sometimes used to prevent outbreaks of genital herpes in people who are infected with the virus. (medlineplus.gov)
  • Acyclovir will not cure genital herpes and may not stop the spread of genital herpes to other people. (medlineplus.gov)
  • When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months. (medlineplus.gov)
  • CDC and others recommend oral acyclovir, oral famciclovir, or oral valacyclovir as drugs of choice for treatment of initial episodes of genital herpes and for episodic treatment or chronic suppressive therapy of recurrent genital herpes. (drugs.com)
  • If you are using acyclovir for treatment of genital herpes, it is important to follow safe sex practices to reduce the risk of giving herpes to your partner, even if there are no symptoms present. (webmd.com)
  • When used for genital herpes, double-blind placebo-controlled studies have showed that orally administered acyclovir significantly reduced the duration of acute infection, pain and new lesion formation, and also the frequency and severity of recurrences in more than 95 per cent of patients. (healthy.net)
  • Acyclovir vs isoprinosine (immunovir) for suppression of recurrent genital herpes simplex infection. (bmj.com)
  • OBJECTIVE--To compare the efficacy and safety of oral acyclovir (400 mg twice daily) with oral isoprinosine (500 mg twice daily) in the suppression of recurrent genital herpes. (bmj.com)
  • CONCLUSIONS--Acyclovir is very effective in suppressing recurrent genital herpes and is clearly superior to isoprinosine which is not clinically useful in the dosage studied. (bmj.com)
  • An overview of the mechanisms of action of and resistance to acyclovir and its major clinical uses will be provided here Acyclovir is an antiviral drug prescribed to treat genital herpes , shingles, and chickenpox. (aclsedu.com)
  • Consult your doctor if pregnant or breastfeeding Acyclovir may also help treat pain associated with an outbreak of genital herpes after the sores heal. (aclsedu.com)
  • Acyclovir injection is used to treat severe infections caused by herpes viruses, including severe forms of genital herpes , shingles, herpes encephalitis (swelling of the brain), and herpes infections in people with other diseases that weaken the immune system. (aclsedu.com)
  • Acyclovir does not protect against the spread of genital herpes. (whatarefor.com)
  • Each gram of white-to-off-white ointment contains 50 mg of acyclovir. (medbroadcast.com)
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  • Research shows effectiveness of topical aciclovir in both the early and late stages of the outbreak as well as improving methodologically and in terms of statistical certainty from previous studies. (wikipedia.org)
  • Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals (sex organs). (mayoclinic.org)
  • Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. (mayoclinic.org)
  • Topical acyclovir may also be used for other conditions as determined by your doctor. (mayoclinic.org)
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  • Applying acyclovir topical to areas when no symptoms are present will not prevent the recurrence of infection. (medbroadcast.com)
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  • Systemic absorption of topical cutaneous acyclovir is negligible. (e-lactancia.org)
  • The aim of this study was to develop a new, rapid and sensitive method for simultaneous determination of aciclovir, three related substances and two preservatives methyl and propyl parahydroxybenzoates present in topical cream. (rsc.org)
  • Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster Acyclovir is a medicine used to treat infections caused by certain viruses. (aclsedu.com)
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  • tell your doctor and pharmacist if you are allergic to acyclovir, valacyclovir (Valtrex), any other medications, or any of the ingredients in acyclovir injection. (epnet.com)
  • Do not use this medication if you are allergic to acyclovir, valacyclovir, or any of the ingredients of the medication. (medbroadcast.com)
  • Aciclovir (ACV), also known as acyclovir, is an antiviral medication. (wikipedia.org)
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  • It is a sterile, aqueous solution for intravenous infusion, containing 50 mg acyclovir per mL in Water for Injection, USP. (nih.gov)
  • Aciclovir Intravenous Infusion is indicated for the purpose of 1. (healthdirect.gov.au)
  • Acyclovir injection is used to treat herpes simplex encephalitis (brain infection with swelling caused by the herpes virus) and herpes infections in newborn infants. (epnet.com)
  • Intravenous acyclovir is the treatment of choice in biopsy-proven herpes simplex encephalitis in adults, and has also been successful in the treatment of disseminated herpes simplex in pregnancy and herpes neonatorium Can you get herpes from kissing? (aclsedu.com)
  • Acyclovir-resistant herpes simplex encephalitis in a patient treated with anti-tumor necrosis factor-α monoclonal antibodies. (bvsalud.org)
  • Combined foscavir and acyclovir treatment resolved the herpes simplex encephalitis . (bvsalud.org)
  • To our knowledge , this is the first report of acyclovir -resistant herpes simplex encephalitis in a patient treated with adalimumab . (bvsalud.org)
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  • Valaciclovir and acyclovir act by inhibiting viral DNA replication, but as of 2016 there was little evidence that they are effective against Epstein-Barr virus, they are expensive, they risk causing resistance to antiviral agents, and (in 1% to 10% of cases) can cause unpleasant side effects. (wikipedia.org)
  • This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. (nih.gov)
  • In vitro , acyclovir triphosphate stops replication of herpes viral DNA. (nih.gov)
  • The greater antiviral activity of acyclovir against HSV compared with VZV is due to its more efficient phosphorylation by the viral TK. (nih.gov)
  • Resistance of HSV and VZV to acyclovir can result from qualitative and quantitative changes in the viral TK and/or DNA polymerase. (nih.gov)
  • While most of the acyclovir-resistant mutants isolated thus far from such patients have been found to be TK-deficient mutants, other mutants involving the viral TK gene (TK partial and TK altered) and DNA polymerase have been isolated. (nih.gov)
  • The possibility of viral resistance to acyclovir should be considered in patients who show poor clinical response during therapy. (nih.gov)
  • It can be said that acyclovir "fooled" the polymerase into using it because this subtle structural change makes a big difference in viral DNA synthesis. (acsh.org)
  • This important active substance, aciclovir is the drug of the first choice for treatment of Herpes viral infections. (rsc.org)
  • In a virus-infected cell, a number of sequential, acyclovir mono-triphosphate-acyclovir conversion reactions take place under the influence of viral thymidine kinases. (myphages.com)
  • Involvement of acyclovir triphosphate in the viral DNA strand occurs, after which its synthesis is blocked by competitive inhibition of viral DNA polymerases. (myphages.com)
  • In vivo therapeutically and prophylactically, acyclovir is primarily effective against viral infections caused by herpes simplex. (myphages.com)
  • If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day Acyclovir is used to treat viral infections. (aclsedu.com)
  • Acyclovir is used to treat viral infections. (aclsedu.com)
  • Although she was an acyclovir naïve patient , a mixed viral population (wild-type and acyclovir -resistant bearing a thymidine - kinase mutation ) was identified in the cerebrospinal fluid . (bvsalud.org)
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  • The applicable subheading for Acyclovir, imported in bulk form, will be 2933.59.5900 , Harmonized Tariff Schedule of the United States (HTS), which provides for Heterocyclic compounds with nitrogen hetero-atom(s) only: Compounds containing a pyrimidine ring (whether or not hydrogenated) in the structure: Other: Drugs: Other. (faqs.org)
  • Drugs that do this are called DNA polymerase inhibitors, the most common one being acyclovir. (acsh.org)
  • Acyclovir may interact with certain medications, including other antiviral medications, chemotherapy drugs, and probenecid. (internationalpharmacy.com)
  • Herpes simplex infection is treatable with antiviral drugs, like acyclovir, so there is at least the possibility that treatment with those drugs might also be able to affect the progression to Alzheimer's disease," he said. (medscape.com)
  • Acyclovir belongs to a class of medications known as antivirals. (webmd.com)
  • Acyclovir belongs to the family of medicines called antivirals. (mayoclinic.org)
  • Aciclovir is a nucleoside analogue that mimics guanosine. (wikipedia.org)
  • Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. (medlineplus.gov)
  • Acyclovir Sodium Injection is a synthetic nucleoside analogue, active against herpes viruses. (nih.gov)
  • Acyclovir is a synthetic purine nucleoside analogue with in vitro and in vivo inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2) and varicella-zoster virus (VZV). (nih.gov)
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  • The use of aciclovir (sales data Sweden 2019) has been considered to result in insignificant environmental risk. (janusinfo.se)
  • Acyclovir injection may cause side effects. (epnet.com)
  • If you've used Acyclovir, please help others by sharing your experience with side effects. (askdocweb.com)
  • For severe HSV infections (especially disseminated HSV), IV aciclovir may also be used. (wikipedia.org)
  • Acyclovir is also sometimes used to treat eczema herpeticum (a skin infection caused by the herpes virus) to treat and prevent herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia (condition that causes hairy white or gray-colored patches on the tongue or inside of the cheek). (medlineplus.gov)
  • Acyclovir is used to treat infections caused by certain types of viruses . (medicinenet.com)
  • In addition, in people with a weakened immune system, acyclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections. (medicinenet.com)
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  • If you stop taking acyclovir too soon or skip doses, your infection may not be completely treated or may become more difficult to treat. (medlineplus.gov)
  • Clinical isolates of HSV and VZV with reduced susceptibility to acyclovir have been recovered from immunocompromised patients, especially with advanced HIV infection. (nih.gov)
  • I have been perscribed aciclovir 200 mg 4x day, for infection in my lower lip so far I am at the end of day 2, I wake with headaches and continue throughout the day and today I have suffered dizzyness and disorientation (forgive my spelling) and I have also noticed a change in the colour of my urine. (askdocweb.com)
  • Depending on the severity of the infection, the maximum dose is 400 mg acyclovir 5 times a day. (myphages.com)
  • Acyclovir will not cure herpes , but it can lessen the symptoms of the infection QUESTION: I've had herpes for over 35 years and taken acyclovir to suppress it for nearly that long. (aclsedu.com)
  • Acyclovir does not cure herpes , but it does relieve the pain and make the infection clear up faster. (aclsedu.com)
  • 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545255/0.0/Acyclovir. (hopkinsguides.com)
  • Oral acyclovir therapy initiated within 24 hours of illness for otherwise healthy children with varicella typically will result in a 1-day reduction of fever and approximately a 15% to 30% reduction in the severity of cutaneous and systemic signs and symptoms. (aap.org)
  • Aciclovir is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters. (wikipedia.org)
  • Your symptoms should improve during your treatment with acyclovir. (medlineplus.gov)
  • University of Illinois at Chicago) New research shows that the antiviral activity of the drug -- called phenylbutyrate, or PBA -- was even better when used along with acyclovir, a common HSV-1 treatment. (medworm.com)
  • Although treatment with Acyclovir may reduce symptoms for some people, it is not a cure for chronic fatigue. (askdocweb.com)
  • Acyclovir may be used in the treatment of varicella (chickenpox). (aclsedu.com)
  • It has been shown in limited test studies that the nursing infant is exposed to approximately 0.3 mg/kg/day following oral administration of aciclovir to the mother. (wikipedia.org)
  • Common adverse drug reactions (≥1% of patients) associated with systemic aciclovir therapy (oral or IV) include nausea, vomiting, diarrhea, encephalopathy (with IV use only), injection site reactions (with IV use only) and headache. (wikipedia.org)
  • To date, no significant adverse effects of oral acyclovir therapy in otherwise healthy children have been demonstrated. (aap.org)
  • Recipient(s) will receive an email with a link to 'The Use of Oral Acyclovir in Otherwise Healthy Children With Varicella' and will not need an account to access the content. (aap.org)
  • In patients with severe renal insufficiency, the elimination half-life is 20 hours, and during hemodialysis 5-7 hours (however, the plasma concentration of acyclovir decreases from 60% to baseline. (myphages.com)
  • Acyclovir decreases the severity and duration of these flare-ups. (whatarefor.com)
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  • The concentration is equivalent to 54.9 mg of acyclovir sodium per mL in Water for Injection, USP. (nih.gov)
  • Acyclovir Sodium Injection contains Sodium Hydroxide, NF as inactive ingredient. (nih.gov)
  • Further dilution of Acyclovir Sodium Injection in an appropriate intravenous solution must be performed before infusion (see DOSAGE AND ADMINISTRATION, Administration ). (nih.gov)
  • Acyclovir sodium is the sodium salt of acyclovir, which is formed in situ , with the molecular formula C 8 H 10 N 5 NaO 3 and a molecular weight of 247.19. (nih.gov)
  • At physiologic pH, acyclovir sodium exists as the unionized form with a molecular weight of 225 and a maximum solubility in water at 37°C of 2.5 mg/mL. (nih.gov)
  • Pennington, NJ, Zydus Pharmaceuticals (USA) Inc. is voluntarily recalling four lots of Acyclovir Sodium Injection, 50 mg/mL, 10 mL and 20 mL vials, to the Hospital/User level after receiving several complaints of crystallization in vials. (medworm.com)
  • WASHINGTON DC, A recall notice published on the U.S. Food and Drug Administration's website states that Zydus Pharmaceuticals (USA) Inc has issued a national recall of its Acyclovir Sodium Injection, 50 mg/mL, 10 mL, and 20 mL vials due to crystallization. (yourlawyer.com)
  • Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles. (wikipedia.org)
  • Precautions and warnings for Acyclovir: Before taking Acyclovir, inform your doctor if you have any medical conditions, such as kidney disease or a weakened immune system. (internationalpharmacy.com)