• Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. (cusabio.com)
  • different proteins show the low muscle neighbouring a PI3K-binding I Activin complex( ACVR1B or ACVR1C), a T-cell II Activin transition( ACVR2A or ACVR2B), and an EGF-CFC explanation( CRIPTO or CRYPTIC). (familie-vos.de)
  • The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. (wikipedia.org)
  • Nodal binds to ACVR2B and then forms a complex with ACVR1C. (wikipedia.org)
  • ACVR1C is a type I receptor for the TGFB family of signaling molecules. (wikipedia.org)
  • Pharmacological inhibition of the ACVR1C receptor using SB505124, a selective inhibitor of ALK4/5/7 receptors, significantly reduced growth (Figure 3a, c, e) and invasion (Figure 3b, d, f) of cultured retinoblastoma cells in a dose-dependent manner. (medkoo.com)
  • Human ACVR1C genome location and ACVR1C gene details page in the UCSC Genome Browser. (wikipedia.org)
  • Hippocampal samples harvested from these mice following learning show increases in several disease-related microRNAs targeting the activin A receptor type 1C (ACVR1C), a component of the transforming growth factor-β receptor superfamily. (elifesciences.org)
  • Human ACVR1C genome location and ACVR1C gene details page in the UCSC Genome Browser. (wikipedia.org)
  • 14 disease terms (MeSH) has been reported with ACVR1C gene. (cdc.gov)
  • Furthermore, the absence of translin/trax abolishes synaptic upregulation of ACVR1C protein after learning. (elifesciences.org)
  • Thus, we define a new memory mechanism by which learning reverses microRNA-mediated silencing of the novel plasticity protein ACVR1C via translin/trax. (elifesciences.org)