• Cholangitis is an infection of the biliary tract with the potential to cause significant morbidity and mortality. (medscape.com)
  • Cholangitis has significant potential for mortality and morbidity, especially if left untreated. (medscape.com)
  • morbidity and mortality, including premature delivery, and WIC-PC, conducted by the U.S. Department of Agriculture, other adverse outcomes ( 1 ). (cdc.gov)
  • Morbidity and mortality were high, as is expected with acute-on-chronic liver failure, he noted. (the-hospitalist.org)
  • Malaria in pregnant people is associated with high risks of both maternal and perinatal morbidity and mortality. (cdc.gov)
  • Hepatorenal Syndrome-Acute Kidney Injury (HRS-AKI), a serious complication of decompensated cirrhosis, has limited therapeutic options and significant morbidity and mortality. (ilts.org)
  • Trauma is the primary cause of mortality and morbidity in the pediatric population. (netce.com)
  • This course will focus on the patterns of childhood trauma and measures to reduce the mortality and morbidity of these devastating injuries. (netce.com)
  • Severe alcoholic hepatitis is implicated as a costly, worldwide public health issue with high morbidity and mortality. (wjgnet.com)
  • Little is known about the burden of morbidity and mortality, which can be high in chronic liver disease or immunocompromised states. (bvsalud.org)
  • AIMS: To record the morbidity and mortality of HEV in Scotland. (bvsalud.org)
  • Although acute liver failure (ALF) is a rare clinical presentation in the ED, it carries a high mortality, morbidity, and resource cost. (emdocs.net)
  • In many countries of Africa and Asia, infection with HIV has further increased morbidity and mortality from TB. (myhealth.gov.my)
  • Limitations of Use: No incremental benefit of ezetimibe and simvastatin tablets on cardiovascular morbidity and mortality over and above that demonstrated for simvastatin has been established. (tevapharm.com)
  • NCDs have both high morbidity and mortality and high treatment costs, not only for the diseases themselves but also for their complications. (dovepress.com)
  • Another reason is exposure to behavioural and physiological risk factors (Figure 1) which are responsible for 75% of CVDs.1 These risk factors have been prioritized according to their impact on mortality and morbidity, possibility of modification through primary prevention, and quantification by available easy standardized methods. (who.int)
  • The African Region is facing two problems related to diet and malnutrition: (i) undernutrition which is still the main cause of infant and childhood morbidity and mortality, and (ii) obesity, which is becoming a leading risk factor for CVD and diabetes, especially in urban areas. (who.int)
  • Pulmonary arterial hypertension (PAH) remains a disease with high morbidity and mortality rates despite recent advances in therapy and overall improved survival. (ersjournals.com)
  • Patient A, a 66-year-old Singaporean-Chinese man, had a history of chronic renal disease secondary to obstructive uropathy. (cdc.gov)
  • Clinically, he had systemic inflammatory response syndrome complicated by acute-on-chronic renal failure. (cdc.gov)
  • WASHINGTON - Treatment with carvedilol reduced the incidence of sepsis and acute kidney injury and improved survival at 28 days but did not significantly reduce the progression of esophageal varices in patients with acute-on-chronic liver failure. (the-hospitalist.org)
  • A total of 136 patients with acute-on-chronic liver failure with small or no esophageal varices and a hepatic venous pressure gradient (HVPG) of 12 mm Hg or greater were enrolled in a single center, prospective, open-label , randomized controlled trial: 66 were randomized to carvedilol and 70 to placebo, according to Sumeet Kainth , MD, of the Institute of Liver and Biliary Sciences in New Delhi. (the-hospitalist.org)
  • Patients with acute on chronic kidney disease fared the worst. (the-hospitalist.org)
  • How common is peripherally inserted central catheter (PICC) use in patients with advanced chronic kidney disease (CKD), and are there associated complications? (the-hospitalist.org)
  • V. vulnificus is 80 times more likely to spread into the bloodstream in people with compromised immune systems, especially those with chronic liver disease. (wikipedia.org)
  • In someone with a compromised immune system, particularly those with chronic liver disease, it can infect the bloodstream, causing a severe and life-threatening illness characterized by fever and chills, decreased blood pressure (septic shock), and blistering skin lesions. (wikipedia.org)
  • Terlipressin improves renal function in some patients with HRS-1, while liver transplantation (LT) is a curative treatment for advanced chronic liver disease. (ilts.org)
  • Thirty-five (6.7%) patients developed acute or acute-on-chronic liver failure with two requiring transplant. (bvsalud.org)
  • Disease severity was assessed using Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores. (biomedcentral.com)
  • 30% had chronic kidney disease, 37% had coronary artery disease, 29% had diabetes mellitus, and 21% had chronic liver disease. (qxmd.com)
  • Oliguria and less frequently anuria were at one time considered signatures of ARF and discriminators for chronic renal failure. (vin.com)
  • Quantitation of urine output may not sufficiently differentiate acute renal failure from polyuric forms of chronic renal failure. (vin.com)
  • A history of weight loss, polyuria, polydipsia, nocturia or isosthenuria, or laboratory evidence of preexisting renal insufficiency suggest an underlying chronic condition. (vin.com)
  • Many animals with compensated and asymptomatic chronic renal insufficiency sustain subtle insults (e.g., fever, concomitant disease, vomiting, diarrhea, congestive heart failure, drug administration), which precipitate a seemingly acute uremic crisis (designated A acute-on-chronic@ renal failure). (vin.com)
  • Because of the abrupt onset of uremia, patients are usually well fleshed, have glossy well groomed hair coats, and pink mucous membranes in contrast to animals with chronic diseases and chronic renal failure. (vin.com)
  • However, acute uremia is frequently superimposed on other diseases or chronic renal failure, and the physical manifestations of these primary conditions may dominate the clinical presentation and mask the features of ARF. (vin.com)
  • If the person has previously had liver disease it is termed acute on chronic liver failure. (patient.info)
  • Patients with chronic liver disease may have liver atrophy. (patient.info)
  • Acute failure of the kidneys is a condition in which there is a rapid loss of the normal function of your kidneys, due to a sudden, acute or chronic insult. (healthengine.com.au)
  • Multimorbidity is defined as the co-existence of two or more chronic conditions in the same patient. (racgp.org.au)
  • Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic, debilitating disorder that most frequently presents in early adulthood and usually continuous throughout the life of the patient. (medscape.com)
  • Just as NIOSH recommends that fire departments implement effective prevention programs to address the risk factors for cardiovascular disease, we would like to see every workplace preventing work-related illness, injury, and disability and promoting healthy living and lifestyles to reduce and prevent chronic disease. (cdc.gov)
  • The outcomes of interest were the time-dependent incidence rates of ICB and the associated mortality. (frontiersin.org)
  • Children at high risk for prolonged mechanical ventilation (PMV) after liver transplantation (LT) need to be identified early to optimize pulmonary support, allocate resources, and improve surgical outcomes. (ilts.org)
  • Effective therapeutics are urgently needed to counter infection and improve outcomes for patients suffering from COVID-19 and to combat this pandemic. (biorxiv.org)
  • From routine wellness & preventive health care to innovative life-saving treatments and diagnostic services, Apollo Hospitals has touched more than 120 million lives from over 120 countries, offering the best clinical outcomes. (apollohospitals.com)
  • Women with severe preeclampsia and liver involvement may develop HELLP syndrome ( h emolysis, e levated l iver enzymes, and l ow p latelet counts), which increases the risk of adverse maternal and fetal outcomes. (aafp.org)
  • Patient characteristics, dialysis status, and major outcomes were determined and stratified by clinical site. (qxmd.com)
  • In a study conducted by Shih and colleagues in patients with cancer in Taiwan, continuous mechanical ventilation for more than 21 days was associated with poor outcomes, particularly in the subgroups of patients with metastases, lung cancer, or liver cancer. (biomedcentral.com)
  • Furthermore, no previous data on outcomes of critically ill patients with different types of solid malignancies are available. (biomedcentral.com)
  • Revascularization for Acute Coronary Syndromes Revascularization is the restoration of blood supply to ischemic myocardium in an effort to limit ongoing damage, reduce ventricular irritability, and improve short-term and long-term outcomes. (msdmanuals.com)
  • 13 Socioeconomic factors have been associated with poorer outcomes and higher disease activity, 14 although it remains unclear whether it plays a role in disease susceptibility or subsequent progression. (lww.com)
  • This meta-analysis aimed to investigate whether FLD or NAFLD carry a higher risk of untoward outcomes in AP. (mdpi.com)
  • Details for: Incidence, underlying conditions, and outcomes of patients receiving acute renal replacement therapies in tertiary cardiac intensive care units: An analysis from the Critical Care Cardiology Trials Network Registry. (medstarauthors.org)
  • BACKGROUND: The prevalence of renal disease in cardiac intensive care units (CICUs) is increasing, but little is known about the utilization, concurrent therapies, and outcomes of patients requiring acute renal replacement therapy (RRT) in this specialized environment.CONCLUSIONS: These data underscore the risks associated with the provision of renal support in patients with primary cardiovascular problems and the need to develop standardized indications and potential futility measures in this specialized population. (medstarauthors.org)
  • BACKGROUND: The prevalence of renal disease in cardiac intensive care units (CICUs) is increasing, but little is known about the utilization, concurrent therapies, and outcomes of patients requiring acute renal replacement therapy (RRT) in this specialized environment. (medstarauthors.org)
  • The aim of this study was to examine the causes and outcomes of hospitalisation in patients with pulmonary arterial hypertension (PAH). (ersjournals.com)
  • The short-term outcomes after discharge are poor and remarkably worse in patients with underlying CTD or renal impairment. (ersjournals.com)
  • In contrast with left heart failure (LHF), the course and outcomes of acute or decompensated RHF have been seldom described [ 1 , 2 ]. (ersjournals.com)
  • Thus our study aimed to analyse the causes, clinical characteristics and outcomes of hospitalisation, as well as prognostic factors for mortality, in a cohort of PAH patients closely followed at a specialised pulmonary hypertension clinic. (ersjournals.com)
  • African Medical Journal describing its use of service claims data to patient investigation and treatment, as well as providing a framework determine standardised mortality rates, across hospital systems, for against which clinical outcomes can be measured. (who.int)
  • Factors reportedly associated with a poor prognosis include old age, female sex, acute renal failure, preexisting cirrhosis, and malignant biliary obstruction. (medscape.com)
  • Longstanding recurrent cholangitis can cause secondary biliary cirrhosis (SBC), portal hypertension, and liver failure. (medscape.com)
  • Patient B, a 45-year-old Malaysian-Chinese man with diabetes mellitus, had undergone a cadaveric liver transplant in 2001 for hepatitis B liver cirrhosis. (cdc.gov)
  • This study investigated the performance of the MELD 3.0 score in predicting the 3-month survival of East Asian patients with cirrhosis compared with the other MELD-based scores. (ilts.org)
  • may also develop in patients with cirrhosis, especially if iron accumulation coexists. (merckmanuals.com)
  • Cirrhosis and haematological malignancy are significant predictors of mortality. (bvsalud.org)
  • If not treated promptly, malaria may progress to severe disease, a life-threatening stage, in which mental status changes, seizures, renal failure, acute respiratory distress syndrome, and coma may occur. (cdc.gov)
  • however, patients with severe or toxic cholangitis may not respond and may require emergency biliary drainage. (medscape.com)
  • The subgroup of patients requiring early surgery presents the most severe disease. (biomedcentral.com)
  • Coronary artery bypass graft surgery (CABG) offers a better survival rate than percutaneous coronary intervention (PCI) and is therefore the treatment of choice in patients with severe coronary artery disease (CAD). (frontiersin.org)
  • Most patients with COVID-19 have mild symptoms, but about 5% develop severe symptoms, which can include acute respiratory distress syndrome, septic shock, and multiple organ failure . (biomerieux.com)
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease of 2019 (COVID-19) 1 , a pandemic that has caused more than 2 million deaths worldwide, and continues to be a public health emergency 2 . (biorxiv.org)
  • Myocardial ischemia is frequently associated with patients hospitalized for moderate-to-severe CO exposure and is a predictor of mortality. (medscape.com)
  • Creatinine kinase, urine myoglobin: Nontraumatic rhabdomyolysis can result from severe CO toxicity and can lead to acute renal failure. (medscape.com)
  • Pregnant women who are remote from term and have severe preeclampsia are best managed in a tertiary care center or in consultation with an obstetrician-gynecologist who has expertise in managing high-risk pregnancies. (aafp.org)
  • RRT is often required for patients with severe AKI, but blood purification therapy (BPT) other than RRT is also an option for some critically ill patients. (biomedcentral.com)
  • Consequently, patients with severe underlying diseases could receive prolonged mechanical ventilation. (biomedcentral.com)
  • Patients are at high risk of severe disease progression with ARDS and/or multiple organ failure, and at high risk of mortality. (who.int)
  • Acute liver failure is the clinical manifestation of sudden and severe hepatic injury, and has a variety of underlying etiologies, including drug toxicity, viral infections, autoimmune and genetic disorders, thrombosis, malignancy, heat injury, and ischemia. (emdocs.net)
  • The loss of hepatocyte function results in liver necrosis, as well as a release of toxins and cytokines leading to severe systemic inflammation and secondary bacterial infections from decreased immunity. (emdocs.net)
  • In countries with high TB prevalence like Malaysia, infants are generally immunized as soon after birth as possible with a single dose of BCG, which protects against severe forms of TB in infancy and early childhood. (myhealth.gov.my)
  • 3 Males and patients with later age of onset tend to have more severe disease and poorer prognosis. (lww.com)
  • COVID-19 patients more likely to die over the course of their hospitalization were those presenting a joint association between ICU admission with either severe COVID-19 or even mild/moderate COVID-19, hypokalemia, and higher levels of BUN, WBC, and LDH measured at hospital admission. (frontiersin.org)
  • Complications include pyogenic liver abscess, cholangiolytic abscess (usually small and multiple) in the liver, longstanding recurrent cholangitis (eg, Asiatic cholangitis), and acute renal failure. (medscape.com)
  • Thirty-seven (7.2%) patients reported neurological complications with 10 developing neuralgic amyotrophy, 6 Guillain-Barré and 2 encephalitis. (bvsalud.org)
  • Neurological and renal complications occur in a significant minority. (bvsalud.org)
  • There is a changing spectrum of ARF in the critically ill, characterized by a large burden of comorbid disease and extensive extrarenal complications, obligating the need for dialysis in the majority of patients. (qxmd.com)
  • 23-25 Likewise, acute renal failure and hepatorenal syndrome are important complications of ALF and are primarily a result of the hemodynamic alterations in ALF. (emdocs.net)
  • These medical professionals can do everything in their power to protect their patients from experiencing complications, but stuff still happens. (scoliosis.org)
  • Since the majority of patients developed AKI after ICU referral and 40% of them were admitted to ICU within 2 days since hospital admission, these patients may have been already in critical clinical conditions at admission, despite being affected by a mild/moderate form of COVID-19, suggesting the need of early monitoring of these patients for the onset of eventual systemic complications. (frontiersin.org)
  • If the E-coli toxins are absorbed into the blood stream, it can cause more serious complications, including sudden kidney failure. (schmidtandclark.com)
  • Lead is absorbed by the proximal tubular cells of the renal tubules, where it binds to specific lead-binding proteins. (medscape.com)
  • Furthermore, ACE-2 is highly expressed in renal proximal tubules, where SARS-CoV-2 particles were detected postmortem in podocytes of COVID-19 patients, suggesting that the kidneys could also be one of the targets of SARS-CoV-2 ( 6 , 7 ). (frontiersin.org)
  • These cancers could be evaluated in a mortality study and in a cancer incidence study. (cdc.gov)
  • The 1-year cumulative incidence of ICB was 0.76%, with a relatively high incidence rate (9.93 cases per 1,000 person-years) within the first 1-30 days. (frontiersin.org)
  • In an unselected nationwide population undergoing CABG, the incidence of ICB was non-negligible and showed a relatively high incidence rate during the early postoperative period. (frontiersin.org)
  • Despite the importance of identifying the incidence pattern and risk factors for ICB in patients undergoing CABG, there is limited available information concerning this, including indirect data from drug trials or unselected stroke populations ( 7 - 10 ). (frontiersin.org)
  • Therefore, in the present study, we investigated the incidence, predictors, and prognostic impact of ICB in a nationwide population of patients undergoing CABG during a long-term follow-up period. (frontiersin.org)
  • Among Fredrickson types, during the 5-year double-blind portion of the primary prevention component of the Helsinki Heart Study, the greatest reduction in the incidence of serious coronary events occurred in Type IIb patients who had elevations of both LDL-cholesterol and total plasma triglycerides. (nih.gov)
  • Conversely, in the USA and much of Europe, the incidence of virally associated liver failure has declined substantially, with most cases now arising from drug-induced liver injury, frequently from acetaminophen or idiosyncratic drug reactions. (emdocs.net)
  • [ 1 ] Globally, the incidence varies and viral infection accounts for the majority of cases of liver failure. (patient.info)
  • Acute failure of the kidneys is not a rare condition, with the incidence depending on the definition used and the population studied. (healthengine.com.au)
  • A large multinational study was recently published in 2005, which studied over 29000 ICU patients in multiple countries to try and determine the incidence of acute kidney failure. (healthengine.com.au)
  • The incidence of kidney disease due to bacteria such as streptococci has been gradually decreasing with the increasing living standards in Australia. (healthengine.com.au)
  • Guillain-Barré syndrome (GBS) is a common cause of non-traumatic acute paralysis with an incidence of about 0·62-2·66 per 100 000 person-years in Europe and North America [ 1 , 2 ]. (springeropen.com)
  • The incidence of ventilator-associated pneumonia in GBS patients is about 75% and is more likely to occur with delayed mechanical ventilation [ 16 ]. (springeropen.com)
  • We aimed to estimate the prevalence of AKI since it varies by geographical settings, time periods, and populations studied and to investigate whether clinical information and laboratory findings collected at hospital admission might influence AKI incidence (and mortality) in a particular point in time during hospitalization for COVID-19. (frontiersin.org)
  • In order to examine how the clinical factors influenced AKI incidence and all-cause mortality during hospitalization, survival analysis using the Cox proportional-hazard models was adopted. (frontiersin.org)
  • AKI incidence was significantly enhanced by diabetes, hyperkalemia, higher levels of WBC count, and blood urea nitrogen (BUN). (frontiersin.org)
  • Although usually benign, CHIKV infection may on rare occasions lead to neurologic and hepatic manifestations with high illness and mortality rates ( 2 ). (cdc.gov)
  • A hypertensive emergency is a sharp rise in blood pressure to a level above 180/120 mmHg that is associated with target organ damage, often involving exigent neurologic, cardiovascular, or renal manifestations. (nursingcenter.com)
  • In this article I highlight adult SLE manifestations and treatments pertinent to the anesthesiologist and discuss perioperative management of these complex patients. (lww.com)
  • 2 Systemic manifestations of this acute skin failure may include pulmonary, renal, and gastrointestinal involvement. (clinicaladvisor.com)
  • The renal manifestations of acute lead poisoning are usually reversible after cessation of lead exposure and, if indicated, chelation therapy. (medscape.com)
  • We report 2 immunocompromised patients with CHIKV infection associated with peritonitis, encephalitis, and secondary bacterial infections. (cdc.gov)
  • Myopathy sometimes takes the form of rhabdomyolysis with or without acute renal failure secondary to myoglobinuria, and rare fatalities have occurred. (tevapharm.com)
  • Among patients with AKI, 19% required dialysis, and half of them died in the hospital. (biomerieux.com)
  • Acute renal failure was accompanied by extrarenal organ system failure in most patients, even those who did not require dialysis. (qxmd.com)
  • Three hundred and ninety-eight (64%) patients required dialysis. (qxmd.com)
  • There are no national level data on types of dialysis in use for acute kidney injury (AKI). (umn.edu)
  • We aimed to assess trends in dialysis modality for AKI and mortality associated with each modality from 1998 to 2005. (umn.edu)
  • Using data from the 5 Medicare cohort, we identified individuals with AKI requiring dialysis. (umn.edu)
  • Mortality was defined as death during 30 days after the first dialysis session. (umn.edu)
  • Mortality associated with different dialysis modalities is likely the result of severity of illness. (umn.edu)
  • What of real-life cases such as those of people suffering from acute renal failure, such that they must either be on near-constant dialysis or receive transplanted kidneys? (whatswrongwiththeworld.net)
  • METHODS: In the Critical Care Cardiology Trials Network, 16 centers submitted data on CICU admissions including acute RRT (defined as continuous renal replacement therapy and/or acute intermittent dialysis). (medstarauthors.org)
  • Hemodynamic parameters also were comparable, with a mean HVPG of about 19, Dr. Kainth said at the annual meeting of the American Association for the Study of Liver Diseases. (the-hospitalist.org)
  • Our Spine doctors will check for list of common spine diseases and conditions of the patient and provide treatment based on the observation. (apollohospitals.com)
  • We analyzed data of 2371 patients who underwent BPT in the intensive care units of 43 facilities to investigate patient characteristics, disease severity, modes of BPTs, including the dose of continuous renal replacement therapy (CRRT) and hemofilters, treated diseases, and the survival rate for each disease. (biomedcentral.com)
  • CRRT was the most commonly used mode for many diseases, including acute kidney injury (AKI), multiple organ failure (MOF), and sepsis. (biomedcentral.com)
  • JSBPCC conducted this cohort study using a nationwide registry of critically ill patients who were treated with BPT in 2018, with the aim of clarifying its current status, including the number of critically ill patients treated with BPT, the diseases treated, the mode of BPT, and survival rates. (biomedcentral.com)
  • Seychelles has done much to tackle noncommunicable diseases, and our successes in, for example, reducing the use of tobacco and the rate of high blood pressure, are encouraging signs of what can be achieved. (who.int)
  • Acute renal failure is frequently a complication of other surgical or medical diseases and must be recognized within the clinical features of these associated disorders. (vin.com)
  • The clinical presentation and outcome of ARF varies depending on the cause, severity, previous therapy, and associated diseases predisposing the renal injury. (vin.com)
  • Multinomial logistic regression analysis showed that white race, presence of sepsis, atherosclerotic heart diseases, peripheral vascular diseases, dysrhythmia, gastrointestinal and liver diseases, and any year after 2000 were independently associated with higher odds of using CRRT after adjusting for other variables. (umn.edu)
  • The differential diagnosis for SJS/TEN includes erythema multiforme (EM), autoimmune bullous diseases (including linear IgA dermatosis), autoimmune disease (including bullous lupus erythematosus), staphylococcal scalded skin syndrome (SSSS), graft-vs-host disease (GVHD), generalized fixed bullous drug eruption, and acute generalized exanthematous pustulosis (AGEP). (clinicaladvisor.com)
  • The review finds that a PHC service approach, which deals with health in a comprehensive way, including the promotion, prevention, and control of diseases, can be useful in both high and low resource settings. (dovepress.com)
  • Kidney involvement in COVID-19 is frequent, and up to half of all hospitalized COVID-19 patients develop acute kidney injury (AKI). (biomerieux.com)
  • Several reports suggested that acute kidney injury (AKI) is a relatively common occurrence in hospitalized COVID-19 patients, but its prevalence is inconsistently reported across different populations. (frontiersin.org)
  • Diabetes and comorbidities did not increase the mortality risk among these hospitalized COVID-19 patients. (frontiersin.org)
  • The prevalence of systemic lupus erythematosus (SLE) ranges from 7.4 to 159.4 per 100,000 of population, with the highest rates among United Kingdom residents of Afro-Caribbean descent, and non-White populations elsewhere. (lww.com)
  • Other well established determinants of multimorbidity include socioeconomic status and gender (higher prevalence in females). (racgp.org.au)
  • 3 The prevalence of multimorbidity among Australian Aboriginal and Torres Strait Islander peoples is 2.59 times that of non-Indigenous Australians, a factor that contributes significantly to higher mortality. (racgp.org.au)
  • The prevalence of fatty liver disease (FLD) and that of non-alcoholic fatty liver disease (NAFLD) share some risk factors known to exacerbate the course of acute pancreatitis (AP). (mdpi.com)
  • Studies have suggested enhanced reabsorption and reduced secretion of uric acid, explaining the high prevalence of gout. (medscape.com)
  • The excretory failure is identified by rapid (hours to days) increases in BUN, serum creatinine and phosphate, and variable hyperkalemia and metabolic acidosis. (vin.com)
  • Some of these include: the build up of waste products that the kidneys usually excrete, such as urea and creatinine, high or low concentrations of molecules such as sodium and potassium, low numbers of red blood cells, inability to concentrate the urine properly and build up of excess fluid. (healthengine.com.au)
  • Blood tests can also reveal a low platelet count, low red blood cell count or a higher than normal level of creatinine, a waste product normally removed by your kidneys. (schmidtandclark.com)
  • Predisposing factors for myopathy include advanced age (greater than or equal to 65 years), female gender, uncontrolled hypothyroidism, and renal impairment. (tevapharm.com)
  • At high HbCO levels, even young healthy patients develop myocardial depression. (medscape.com)
  • Acute Myocardial Infarction (MI) Acute myocardial infarction is myocardial necrosis resulting from acute obstruction of a coronary artery. (msdmanuals.com)
  • Unstable Angina Unstable angina results from acute obstruction of a coronary artery without myocardial infarction. (msdmanuals.com)
  • Reduced output from the heart, due to causes such as - myocardial infarction (heart attack) , heart failure , pulmonary embolus (a clot in the lungs), dysfunction of the heart valves. (healthengine.com.au)
  • Was the death specific clinical conditions (i.e. acute myocardial infarction, coronary of this patient expected? (who.int)
  • 2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)
  • The predictors of ICB after CABG were age ≥ 75 years, hypertension, pre-existing dementia, history of ischemic stroke or transient ischemic attack, and end-stage renal disease. (frontiersin.org)
  • World Health Organization functional class prior to admission, renal dysfunction, Charlson comorbidity index, and the presence of CTD were all predictors of mortality after discharge. (ersjournals.com)
  • Hemorrhagic stroke, which is less frequent than ischemic stroke, is a devastating complication of CABG which carries a high risk of incapacitating disabilities and mortality ( 6 ). (frontiersin.org)
  • Hepatopulmonary syndrome (HPS) is a common complication of liver disease defined by abnormal oxygenation and intrapulmonary vascular dilatation, treated with liver transplantation. (ilts.org)
  • When something goes wrong and a patient has a complication or a bad outcome, everyone suffers, including the surgeons and the anesthesiologists. (scoliosis.org)
  • Hemolytic uremic syndrome, or HUS, is a life-threatening type of kidney failure that occurs as a complication of serious cases of foodborne illness. (schmidtandclark.com)
  • The elderly are infection, uncontrolled diabetes mellitus, more likely to bleed persistently because uncontrolled hypertension, decompensated atherosclerotic vessels contract less, and liver disease, renal failure, ischaemic heart surgery may be necessary in a higher pro- disease, autoimmune disorders, and patients portion of patients over 60 years old. (who.int)
  • Mean Model for End-Stage Liver Disease (MELD) scores were about 25. (the-hospitalist.org)
  • The objective was to analyze clinical characteristics of patients with infective endocarditis (IE) requiring surgery when the disease is diagnosed. (biomedcentral.com)
  • Recently, a new predictive model that jointly considers the Model of End-stage Liver Disease (MELD) 3.0 and albumin has been proposed. (ilts.org)
  • Model for End-stage Liver Disease (MELD) and MELDNa are used worldwide to guide graft allocation in liver transplantation (LT). Evidence exists that females are penalized in the present allocation systems. (ilts.org)
  • See also the 2019 American Association for the Study of Liver Disease's practice guidelines for Alcohol-Associated Liver Disease . (merckmanuals.com)
  • There appears to be a threshold effect above which the amount and duration of alcohol use increases the risk of the development of liver disease. (merckmanuals.com)
  • Binge drinking may also increase alcohol-related liver disease. (merckmanuals.com)
  • To know the major causes of this disease progression, understand the basic processes that cause the progression from SIRS to septic shock, and describe the basic treatment plan in caring for these patients. (atsu.edu)
  • Epidemiological studies have shown that both low HDL-cholesterol and high LDL-cholesterol are independent risk factors for coronary heart disease. (nih.gov)
  • Therefore, when MEFOXIN is used in the treatment of patients with pelvic inflammatory disease and C. trachomatis is one of the suspected pathogens, appropriate anti-chlamydial coverage should be added. (rxlist.com)
  • No data were available on the reason for ICU admission, severity of the acute disease, or performance status. (biomedcentral.com)
  • Please note that only clinically relevant strong CYP3A4 inhibitors were considered, please note that protease inhibitors will not be relevant for this study as patients with an immunosuppressive disease are excluded (see also section 8.1.4). (who.int)
  • While there are more than 40 definitions of acute liver failure in use, many of themodern definitions recognize the distinct disease phenotypes and seek to quantify the interval between the onset of symptoms and the development of encephalopathy. (emdocs.net)
  • If this occurs rapidly in a patient with no previous liver disease it is termed acute liver failure. (patient.info)
  • Family history of liver disease (Wilson's disease or haemochromatosis ). (patient.info)
  • Individuals with preexisting end-stage renal disease were excluded. (umn.edu)
  • However, in many Indigenous communities, high incidences of streptococcal infection and kidney disease are still seen. (healthengine.com.au)
  • Problems with the vessels such as build up of fat and clots in arteries (atheroembolic disease), and occlusion of the renal artery. (healthengine.com.au)
  • Acute disease of the kidneys (acute glomerulonephritis ) due to: immune causes, development of antibodies and sometimes from unknown causes. (healthengine.com.au)
  • Covid-19 turned out to be most infectious disease with high and low transmission rate, people infected with Covid virus are subject to experience mild to moderate respiratory illness. (inventiva.co.in)
  • 2,5 Stevens-Johnson syndrome/TEN is associated with hematologic malignancies, liver and kidney disease, and certain infections including HIV. (clinicaladvisor.com)
  • Active liver disease or unexplained persistent elevations in hepatic transaminase levels. (tevapharm.com)
  • Patients often require hospitalisation during the course of their disease, typically for bouts of right heart failure (RHF). (ersjournals.com)
  • Magnetic resonance imaging of the brain of patient B, showing several nonspecific areas of enhancement (arrows), which suggests encephalitis, given the clinical scenario. (cdc.gov)
  • A logistic regression was performed incidents with fatal outcome in many L. poisoning are rare and limited to a few with death versus living as the depend- cases, and constitutes a public health clinical cases. (who.int)
  • Clinical presentation of kidney involvement from COVID-19 can range from mild proteinuria to progressive AKI, requiring renal replacement therapy (RRT). (biomerieux.com)
  • The health status of the patients at inclusion in the clinical trial is rated 5 - 6 according to the WHO scale (see protocol, CATCOVID_v1.2, 27.09.2021, page 13). (who.int)
  • Acute renal failure (ARF) is characterized by a rapid onset of renal insufficiency/failure, reduction in glomerular filtration rate and renal plasma flow, and the clinical and biochemical aftermath of the excretory failure. (vin.com)
  • The manifestation, timing, and severity of ALF's clinical features vary according to its underlying etiology, and a high index of suspicion is required to make an early diagnosis. (emdocs.net)
  • 12,13 The clinical course of ALF follows that of multiple organ failure. (emdocs.net)
  • Clinical presentations include silent ischemia, angina pectoris, acute. (msdmanuals.com)
  • Patients were not required to give informed consent to the study because the analysis used anonymous clinical data using NIS database which contains no identifying patient information and does not require informed consent to use the data. (wjgnet.com)
  • Organ failure maybe the result of increased level of inflammatory mediator levels, endothelial dysfunction, coagulation problems, and infiltration of inflammatory cells into the organs are all contributing factors. (inventiva.co.in)
  • In addition, right ventricular-left ventricular interdependence often leads to left ventricular dysfunction with low cardiac output and consequent systemic hypotension in RHF, which may require the use of vasopressor and inotropic agents. (ersjournals.com)
  • From 2006 through 2013, the estimated number of visits for hypertensive emergency more than doubled, but true hypertensive emergency accounted for only 0.2% of adult ED patients overall and 0.6% of adult ED patients with a diagnosis of hypertension. (nursingcenter.com)
  • Adult patients with PAH evaluated at the Johns Hopkins Pulmonary Hypertension Program were prospectively included in the Hopkins Pulmonary Hypertension Registry. (ersjournals.com)
  • 3 The severity of the condition and its associated mortality can be approximated with the SJS/TEN-specific severity-of-illness score (SCORTEN). (clinicaladvisor.com)
  • Intermittent hemodialysis (IHD), daily intermittent hemodialysis, and continuous renal replacement therapy (CRRT) were defined using Current Procedure Terminology codes. (umn.edu)
  • AKI is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. (biomerieux.com)
  • Acute kidney failure should be treated as a serious condition and is a potential medical emergency. (healthengine.com.au)
  • People who are hospitalized in hospital intensive care units (ICUs) are at very high risk for acute kidney failure. (healthengine.com.au)
  • The most common causes of acute kidney failure are those conditions that cause reduced blood supply to the kidneys. (healthengine.com.au)
  • Generally, causes of acute kidney failure can be divided into three groups - pre-renal (ie affecting the body's volume and vessels supplying the kidneys, renal (within the kidney) and post renal (affecting pathways and structures after the kidneys). (healthengine.com.au)
  • The condition affects the blood and blood vessels which results in the destruction of blood platelets (cells involved in clotting), a low red blood cell count (anemia) and kidney failure due to damage to the very small blood vessels of the kidneys. (schmidtandclark.com)
  • However, approximately 10% of the cases result in HUS, which could lead to kidney failure or death. (schmidtandclark.com)
  • Hemolytic-uremic syndrome (HUS) is associated with sudden decreases in blood platelets, destruction of red blood cells and kidney failure. (schmidtandclark.com)
  • Overview of Acute Coronary Syndromes (ACS) Acute coronary syndromes result from acute obstruction of a coronary artery. (msdmanuals.com)
  • Despite maximal support and prolonged antimicrobial therapy, this patient died after 5 months of hospitalization. (cdc.gov)
  • Eighty-two percent of patients took combination therapy (19% four). (biomedcentral.com)
  • In Jamaica, the greatest mortality occurs between 6 and 12 months old when 10% of patients die despite considerable experience in the diagnosis and therapy of the condition and absence of malaria. (who.int)
  • Renal failure post-LT requiring renal replacement therapy (RRT) is a major risk factor for graft and patient survival. (ilts.org)
  • The Japan Society for Blood Purification in Critical Care (JSBPCC) has reported survey results on blood purification therapy (BPT) for critically ill patients in 2005, 2009, and 2013. (biomedcentral.com)
  • While modest decreases in total and low density lipoprotein (LDL) cholesterol may be observed with gemfibrozil therapy, treatment of patients with elevated triglycerides due to Type IV hyperlipoproteinemia often results in a rise in LDL-cholesterol. (nih.gov)
  • In the primary prevention component of the Helsinki Heart Study, in which 4081 male patients between the ages of 40 and 55 were studied in a randomized, double-blind, placebo-controlled fashion, gemfibrozil therapy was associated with significant reductions in total plasma triglycerides and a significant increase in high density lipoprotein cholesterol. (nih.gov)
  • without knowledge of their own lipid values or double-blind treatment, 60% of patients originally randomized to placebo began therapy with gemfibrozil and 60% of patients originally randomized to gemfibrozil continued medication. (nih.gov)
  • Failure to initiate therapy may result in irreversible parenchymal damage or death. (vin.com)
  • Drug therapy for hypertensive emergency is influenced by end-organ involvement, pharmacokinetics, potential adverse drug effects, and patient comorbidities. (nursingcenter.com)
  • After 12-24 hours had passed and the ulcer, 318 received conservative medical bleeding had clearly stopped, a patient who therapy while surgery was performed on felt hungry was allowed oral feeding. (who.int)
  • Nitroglycerin is preferable to morphine , which should be used judiciously (eg, if a patient has a contraindication to nitroglycerin or is in pain despite nitroglycerin therapy). (msdmanuals.com)
  • Management is generally supportive: In most cases, the best option for treatment of acute-onset diarrhea is the early use of oral rehydration therapy (ORT). (medscape.com)
  • Between 1998 and 2005, there were a total of 18,249 patients identified with AKI requiring renal replacement therapy. (umn.edu)
  • Removal of lead using chelation therapy reverses the proximal reabsorptive defect and removes the intranuclear inclusion bodies of acute lead nephropathy. (medscape.com)
  • Earlier studies on the impact of COVID-19 focused on the pulmonary system, and dysfunctions of other organs were attributed to hyper-inflammatory response and thrombophilia-inducing multiorgan failure (MOF). (frontiersin.org)
  • While aggressive diuresis is usually required in both LHF and RHF, the large increase in transpulmonary gradient due to a fixed resistance in the pulmonary vasculature in PAH complicates the treatment of RHF. (ersjournals.com)
  • citation needed] Vibrio vulnificus is an extremely virulent bacterium that can cause three types of infections: Acute gastroenteritis from eating raw or undercooked shellfish: V. vulnificus causes an infection often incurred after eating seafood, especially raw or undercooked oysters. (wikipedia.org)
  • In sub-Saharan Africa mortality will be much higher, and in some areas estimates derived from the age structure of populations attending clinics suggest that half of those with sickle-cell anaemia have died by the age of five years usually from infections including malaria and pneumococcal sepsis, and from the anaemia itself. (who.int)
  • Bloodstream infections caused by Pseudomonas aeruginosa, Candida albicans , or multidrug resistant Enterococcus faecium is associated with increased mortality. (atsu.edu)
  • It is estimated that the Indigenous population have a ten times greater risk of eventually developing renal failure after they have had bacterial infections, than compared to the non-Indigenous population. (healthengine.com.au)
  • Approximately 5% of people have critical infections and require a venogram "ilator," according to a WebMD report. (inventiva.co.in)
  • CIPRO XR is indicated for the treatment of infections caused by susceptible isolates of the designated microorganisms in the conditions and patient populations listed below. (globalrph.com)
  • In the present study including adults with Guillain-Barré syndrome at high risk of respiratory failure, we did not observe a prevention of pneumonia with early mechanical ventilation. (springeropen.com)
  • On the other hand, several factors may identify a group of patients at high risk of respiratory failure. (springeropen.com)
  • First, more than 80% of GBS patients admitted to the ICU within 7 days of motor-deficit onset, being unable to lift the head, and whom forced vital capacity was of less than 60% of predicted value, eventually presented with acute respiratory failure requiring mechanical ventilation [ 14 ]. (springeropen.com)
  • It was found that CRRT was the most frequently used mode for critically ill patients in Japan and that 28-day survival was lower in those with MOF or sepsis. (biomedcentral.com)
  • Further investigations are required to clarify the efficacy of BPT for critically ill patients. (biomedcentral.com)
  • JSBPCC has created a registry for data from its nationwide surveys of critically ill patients. (biomedcentral.com)
  • Acute renal failure (ARF) in the critically ill is associated with extremely high mortality rates. (qxmd.com)
  • Unlike in most other studies in critically ill patients with cancer, solid malignancies predominated (94% of patients). (biomedcentral.com)
  • Of the 29 269 critically ill patients admitted during the study period, approximately 6% developed acute renal failure during their ICU stay. (healthengine.com.au)
  • CONCLUSION: In Scotland, HEV causes a significant burden of inpatient admissions, organ failure and death. (bvsalud.org)
  • 01). In conclusion, acute RRT in contemporary CICUs was associated with the provision of other advanced therapies and lower survival. (medstarauthors.org)
  • Cholangitis in patients with a biliary-enteric anastomosis (eg, hepatico-jejunostomy or a bilio-biliary anastomosis) after liver transplant indicates anastomotic stricture. (medscape.com)
  • Another 23 experienced adverse events and 2 progressed to liver transplant. (the-hospitalist.org)
  • identify the exact mechanisms of renal injury in COVID-19 patients, and suggest targeted interventions. (biomerieux.com)
  • However, unintentional injury and death rates in children remain high. (netce.com)
  • The etiology of ARF varies geographically as differences in infectious causes will differ regionally as will therapeutic practices that might predispose to acute renal injury. (vin.com)
  • Further research is needed to stratify high-risk patients and personalize therapeutic decisions for preventing ICB after CABG. (frontiersin.org)
  • all of these patients had neurologic sequelae. (medscape.com)
  • Of those patients with negative scan results, only 11% had neurologic sequelae. (medscape.com)
  • Additionally, patients with CHIKV infection typically have arthralgia, arthritis, and tenosynovitis ( 1 ). (cdc.gov)
  • Patients with acute SARS-CoV-2 infection, proven by a positive SARS-CoV-2 PCR test. (who.int)
  • however, an acute infection can have a protracted course. (medscape.com)
  • 830 Hospitalization and Emergency Department identify groups at higher risk for iron deficiency. (cdc.gov)
  • True hypertensive emergencies are characterized by a rapid elevation in blood pressure to a level above 180/120 mmHg and are associated with acute target organ damage, which requires immediate hospitalization for close hemodynamic monitoring and IV pharmacotherapy. (nursingcenter.com)
  • High blood pressure levels that produce no signs or symptoms of target organ damage may be treated without hospitalization through an increase in or reestablishment of previously prescribed oral antihypertensive medication. (nursingcenter.com)
  • All patients received treatment and are improving clinically. (cdc.gov)
  • Zimmer V, Lammert F. Acute bacterial cholangitis. (medscape.com)
  • Successful malaria treatment is dependent on a high index of suspicion for malaria in patients with acute febrile illness, and urgent treatment with effective medication. (samj.org.za)
  • In addition to routinely considering malaria as a cause of febrile illness among patients with a history of international travel to areas where malaria is transmitted , clinicians should consider a malaria diagnosis in any person with a fever of unknown origin regardless of their travel history. (cdc.gov)
  • The risk is higher in areas where local climatic conditions allow the Anopheles mosquito to survive during most of or the entire year and where travelers from malaria-endemic areas are found. (cdc.gov)
  • Post-CABG ICB was associated with a high risk of premature death. (frontiersin.org)
  • However, CABG entails a higher risk of stroke than PCI ( 1 ). (frontiersin.org)
  • Risk factors references Alcohol consumption is high in most Western countries. (merckmanuals.com)
  • 3. recite the factors that increase the risk of a patient getting sepsis and the patient types most like to get sepsis. (atsu.edu)
  • Risk for travellers is limited but travellers are advised to avoid exposure to known TB patients in crowded environments (e.g. hospitals, prisons, or homeless shelters). (myhealth.gov.my)
  • The risk of myopathy is increased by high levels of statin activity in plasma. (tevapharm.com)
  • I'm not sure of this, but I believe that the risk of death is actually higher than the risk of blindness (though both are rare). (scoliosis.org)
  • The patient was almost certainly told that there was a risk of death, and yet she decided to proceed with surgery. (scoliosis.org)
  • In 2019, Discovery Health published a risk adjustment model to determine standardised mortality rates across South African private hospital systems, with the aim of contributing towards quality improvement in the private healthcare sector. (who.int)
  • When designing a risk prediction model, patient-proximate variables with a sound theoretical or proven association with the outcome of interest should be used. (who.int)
  • Performance could be further improved by using summary risk prediction scores such as the EUROSCORE II for coronary artery bypass graft surgery or the GRACE risk score for acute coronary syndrome. (who.int)
  • In this article, we conduct a critical analysis of the methodology patients into risk categories. (who.int)
  • In some patients the syndrome is distinguished by oliguria or anuria, but today this classical feature of ARF is less predictable. (vin.com)
  • About 30% of patients with Guillain-Barré syndrome become ventilator dependent, of whom roughly 75% develop pneumonia. (springeropen.com)
  • A retrospective study of all patients, during 5 years in a tertiary hospital in Spain, which required admission to the ICU with the diagnosis of IE (Duke criteria modified) and required surgery at the same time. (biomedcentral.com)
  • Forty-one percent of patients required ICU admission before surgery with an average stay of 5.6 days. (biomedcentral.com)
  • Three hundred and three patients required admission (59%), totalling 2747 inpatient bed days. (bvsalud.org)
  • Hyponatraemia and low systolic blood pressure upon admission and underlying CTD are the main prognostic factors for in-hospital mortality in patients with PAH admitted for RHF. (ersjournals.com)
  • Most of the patients survived the acute illness but required a disproportionate amount of health-care resources[ 2 ]. (biomedcentral.com)
  • Hepatic failure occurs when the liver loses the ability to regenerate or repair, so that decompensation occurs. (patient.info)
  • There are many causes of hepatic failure and the following represent just a few. (patient.info)
  • AKI treatment strategies are being adapted empirically to treat COVID-19 patients who present the signs and symptoms of kidney damage. (biomerieux.com)
  • All patients have received treatment and are improving. (cdc.gov)
  • More than 90% of patients were men with a mean age of 44 years, and composition of the treatment and placebo groups was similar. (the-hospitalist.org)
  • Patients in the treatment group received a median maximum tolerated dose of carvedilol of 12.5 mg, with a range of 3.13 mg to 25 mg. (the-hospitalist.org)
  • Treatment with carvedilol did not achieve significant reductions in variceal bleeding, "possibly due to the low number of bleeds seen in the study [because of] the exclusion of patients with large varices," Dr. Kainth said. (the-hospitalist.org)
  • In recent years, liver transplantation has emerged as a treatment for patients with stage IV colorectal liver metastases (CRLM). (ilts.org)
  • of heart Failure Treatment study. (qxmd.com)
  • After approximately 6.5 years following randomization, all patients were informed of their original treatment group and lipid values during the five years of the double-blind treatment. (nih.gov)
  • This study is original because it estimates the benefits of maximal treatment intensity in patients with cancer. (biomedcentral.com)
  • ABSTRACT: While acute blood pressure elevations are commonly seen in the ED, not all require emergency treatment. (nursingcenter.com)
  • However, all patients presenting with blood pressure this high should undergo evaluation to confirm or rule out impending target organ damage, which differentiates hypertensive emergency from other hypertensive crises and is vital in facilitating appropriate emergency treatment. (nursingcenter.com)
  • 15% of all duodenal ulcer patients [6-8], or affect the treatment of duodenal ulcer, and significant intervention is required in such as human immunodeficiency virus up to 20% of these patients. (who.int)
  • A standardized short course tuberculosis treatment regimen of six to eight months under direct observation by a trained supervisor (usually healthcare workers) to ensure that the patient takes every dose of medication. (myhealth.gov.my)
  • That means they may require oxygen treatment in a hospital. (inventiva.co.in)
  • Because fluoroquinolones, including CIPRO XR, have been associated with serious adverse reactions [see WARNINGS AND PRECAUTIONS ] and for some patients uncomplicated UTI (acute cystitis) is self-limiting, reserve CIPRO XR for treatment of uncomplicated UTIs (acute cystitis) in patients who have no alternative treatment options. (globalrph.com)
  • 5 The number of associated conditions increases with age, as people with diabetes live longer, partly as a consequence of improved treatment. (racgp.org.au)
  • And final y, it allows patients to The publication sought to transparently examine variations in care make informed decisions about possible treatment options. (who.int)
  • Only 30-50 percent of patients with sepsis have positive blood culture results. (atsu.edu)
  • For patients with sepsis, endotoxin adsorption by direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX-DHP) has been used in Japan since 1994 [ 10 ]. (biomedcentral.com)
  • This subgroup of Type IIb gemfibrozil group patients had a lower mean HDL-cholesterol level at baseline than the Type IIa subgroup that had elevations of LDL-cholesterol and normal plasma triglycerides. (nih.gov)
  • The mean change in LDL-cholesterol among Type IIb patients was -4.1% with gemfibrozil compared to a rise of 3.9% in the placebo subgroup. (nih.gov)
  • In the United States, although 18% of ED patients have severely elevated blood pressure at or above 180/110 mmHg upon presentation, 3 far fewer have hypertensive emergency, as previously defined, which occurs in conjunction with acute or impending target organ damage. (nursingcenter.com)
  • This distribution reflects the fact that sickle-cell trait confers a survival advantage against malaria and that selection pressure due to malaria has resulted in high frequencies of the mutant gene especially in areas of high malarial transmission. (who.int)
  • There are, however, no firm data on the survival of patients with sickle-cell anaemia on the African continent. (who.int)
  • Survival rate and life expectancy were worse in the subgroups with metastases, lung cancer, or liver cancer. (biomedcentral.com)
  • Little is known about the survival of patients with cancer treated with mechanical ventilation, particularly in those with solid malignancies. (biomedcentral.com)
  • Diagnosis and management of acute cholangitis. (medscape.com)
  • Mortality rates, however, were relatively high among patients with qualifying hypertensive emergency who presented to U.S. EDs, at 4.8% in 2006 and 4.5% in 2013, underscoring the need for prompt diagnosis and appropriate management of the condition. (nursingcenter.com)
  • Is my rate of heart failure readmissions artery bypass graft (CABG) surgery, pneumonia and acute stroke). (who.int)
  • When health impact is measured by under-five mortality, sickle-cell anaemia contributes the equivalent of 5% of under-five deaths on the African continent, more than 9% of such deaths in west Africa, and up to 16% of under-five deaths in individual west African countries. (who.int)
  • People aged 60 and up accounted for roughly 70% of deaths during the Covid third wave, which was 15% higher than the fatalities in the second wave. (inventiva.co.in)
  • Although previously more common in high- and upper-middle-income countries, lower-middle-income countries (LMICs) are more affected, with NCDs in LMICs currently accounting for 85- 90% of premature deaths among 30- 69 years old. (dovepress.com)