AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
L-Iditol 2-DehydrogenaseMyocardial Reperfusion InjuryMyocardial IschemiaMyocardiumMyocardial InfarctionWounds and InjuriesReperfusion InjuryBrain InjuriesBrain IschemiaIschemiaAthletic InjuriesSpinal Cord InjuriesIschemic PreconditioningRats, Sprague-DawleyInfarction, Middle Cerebral ArteryDisease Models, AnimalNeuroprotective AgentsAcute Kidney InjuryInjury Severity ScoreLeg InjuriesLung InjuryMice, Inbred C57BLEye InjuriesHypoxia-Ischemia, BrainTime FactorsAcute Lung InjuryNeck InjuriesCerebral InfarctionRecovery of FunctionAbdominal InjuriesIschemic Attack, TransientArm InjuriesBrain InfarctionBlast InjuriesHand InjuriesThoracic InjuriesBrainSpinal InjuriesMice, KnockoutKnee InjuriesRats, WistarCytoprotectionApoptosisReperfusionKidneyAbbreviated Injury ScaleCell DeathFacial InjuriesHeart InjuriesNeuronsCells, CulturedIschemic Preconditioning, MyocardialImmunohistochemistryNecrosisBack InjuriesHead Injuries, ClosedSoft Tissue InjuriesDiffuse Axonal InjuryCerebral CortexSpinal Cord IschemiaCraniocerebral TraumaDrug-Induced Liver InjuryOccupational InjuriesL-Lactate DehydrogenaseAnoxiaCarotid Artery InjuriesBrain EdemaPeripheral Nerve InjuriesMice, TransgenicKidney TubulesHypothermia, InducedAnkle InjuriesCerebrovascular CirculationProtective AgentsRetinal DiseasesSignal TransductionMyocytes, CardiacParaplegiaIn Situ Nick-End LabelingVascular System InjuriesWounds, NonpenetratingPerfusionConstrictionOxidative StressCell SurvivalGlucoseElectroacupunctureCell HypoxiaLigationAstrocytesKidney Tubules, ProximalCardiotonic AgentsAccidents, TrafficRetinal VesselsBlotting, WesternTrauma Severity IndicesFoot InjuriesFinger InjuriesWarm IschemiaWounds, Penetrating
InfarctionIschemiaPercutaneous coronary intNecrosisReperfusionStrokeMyocardiumPerfusionSyndromeClinicalRemote ischaemicInfarctions occurTissueTroponinThromboticPreconditioningInflammationIncreasesMarkersStrokesComplicationsIncidenceDiagnosisPrimaryKidneySymptomsCoronary syndromesCardiac muscleAbnormalProtectsMortalityDamageTreatmentDysfunction
Infarction61
Ischemia28
  • This review summarizes our current understanding of the role of cannabinoid receptors in the pathophysiology of atherosclerosis and myocardial ischemia and explores their use as therapeutic targets in the treatment of ischemic heart disease. (aspetjournals.org)
  • Endocannabinoid signaling is also activated by myocardial ischemia. (aspetjournals.org)
  • Before ischemia, acute troglitazone treatment had no effect on LV function, electrocardiogram, or substrate utilization. (diabetesjournals.org)
  • Acute treatment with troglitazone increases susceptibility to ventricular fibrillation during myocardial ischemia and reperfusion. (diabetesjournals.org)
  • Low arterial flow, low oxygen retention and presence of anaerobic glycolysis characterize myocardial ischemia. (edu.pk)
  • Two forms of silent myocardial ischemia are recognized. (edu.pk)
  • It has documented that ST segment shift either increased or decreased correlate well with other markers of myocardial ischemia. (edu.pk)
  • contemporary approach towards diagnosing acute myocardial ischemia. (medline.ru)
  • It is necessary to search for new forensic medical criteria proceeding from the practical experience of forensic medical examination when it is sometimes quite difficult to establish that death occurred as the result of the acute myocardial ischemia and to make a differential diagnostics. (medline.ru)
  • We have researched a possibility to apply the Enzyme Multiplied Immunoassay Technique (EMIT-test) for Troponin T to diagnose death resulting from the acute myocardial ischemia in the biological laboratory of the Leningrad Regional Bureau of Forensic Medical Examination. (medline.ru)
  • It means that Troponin T lends itself most widely for a diagnosis uniting the advantages of the quick and slow markers with the acute myocardial ischemia. (medline.ru)
  • At first, acute ischemic stroke is a stressful condition, which may cause coronary demand ischemia, especially in patients with preexisting chronic heart failure, atrial fibrillation or coronary artery disease. (eso-stroke.org)
  • 4 Large strokes in particular may also induce a neurogenic heart syndrome through bursts of neurogenic sympathetic activity and catecholamine release, leading to coronary demand ischemia and myocardial necrosis. (eso-stroke.org)
  • Protection of the heart against injury from acute ischemia remains challenging for emergency physicians and cardiologists because there are no therapies proven to directly protect the heart against the deleterious effects of ischemia in humans. (mcw.edu)
  • Coronary thrombolysis and mechanical revascularization have revolutionized the primary treatment of acute MI, largely because they allow salvage of the myocardium when implemented early after the onset of ischemia. (medscape.com)
  • 2 Paradoxically, reperfusion itself can enlarge the infarct size, by complex mechanisms collectively termed ischemia/reperfusion injury. (dovepress.com)
  • 3 In a previous study, different pharmacological principles that aimed to reduce ischemia/reperfusion injury failed to show effect. (dovepress.com)
  • It has previously been demonstrated that phosphatidylinositol‑3‑kinase (PI3K)/Akt and cleaved caspase‑3 serve critical roles in the apoptosis of cardiac myocytes following ischemia/reperfusion injury. (spandidos-publications.com)
  • Increases in knowledge have revealed that the common pathophysiological scenario, myocardial ischemia reperfusion injury, including ischemia/reperfusion (I/R) and hypoxia/reoxygenation (H/R) forms of injury, results in depressed myocardial function and harmful morphological alterations, which may lead to heart failure ( 4 ). (spandidos-publications.com)
  • Clenbuterol overdose can cause myocardial injury and ischemia. (kimiamahvand.ir)
  • It may be due to the inotropic and chronotropic effects that lead to demand ischemia, though there may also be a direct myocardial toxicity [6]. (kimiamahvand.ir)
  • During myocardial ischemia (lack of blood flow to the muscle tissue of the heart, commonly referred to as a "heart attack"), blood flow is interrupted because of damage to one or more of the coronary blood vessels that irrigate the heart. (prohealth.com)
  • Research done in animals shows that treatment with NAD+ precursors like NMN have cardioprotective effects against ischemia/reperfusion injury (4). (prohealth.com)
  • The authors carried out tests on an animal model to investigate the individual and combined effects of melatonin and NMN on myocardial function, mitochondrial activity, and oxidative stress status following ischemia/reperfusion injury in aged rat hearts. (prohealth.com)
  • We have recently shown that postischemic administration of intralipid protects the heart against ischemia-reperfusion injury. (silverchair.com)
  • To determine whether ischemia-reperfusion injury causes this acute-phase response, we studied the temporal relation between plasma levels of CRP and ischemic episodes in 48 patients with unstable angina and 20 control patients with active variant angina, in which severe myocardial ischemia is caused by occlusive coronary artery spasm. (ox.ac.uk)
  • CONCLUSIONS: The normal levels of CRP in variant angina, despite a significantly larger number of ischemic episodes and greater total ischemic burden, and the failure of CRP values to increase in unstable angina indicate that transient myocardial ischemia, within the range of duration observed, does not itself stimulate an appreciable acute-phase response. (ox.ac.uk)
  • Symptoms of acute myocardial ischemia (ie, resulting from a primary coronary artery event). (who.int)
Percutaneous coronary int1
  • At the same time, the use of tirofiban as an adjunctive medication in the catheterization laboratory (Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis [RESTORE] regimen) for the prevention of ischemic complications during percutaneous coronary intervention (PCI) gave controversial results. (jacc.org)
Necrosis5
  • w3 The associated ischaemic injury and subsequent myocardial necrosis spreads from the subendocardial to the subepicardial myocardium in a time span of several hours. (bmj.com)
  • An increase in LDH isoenzyme-1 is characteristic of myocardial damage but hemolysis and cortical necrosis also can generate this result 3 . (edu.pk)
  • Acute myocardial infarct (MI), commonly known as a heart attack, is a condition characterized by ischemic injury and necrosis of the cardiac muscle. (medscape.com)
  • For the end point infarct size, estimated by biomarkers of myocardial necrosis, an overall pooled effect was SMD =−0.58, 95% CI: −0.96 to −0.19. (dovepress.com)
  • Additionally, it may clinically manifest with myocardial necrosis, cardiac arrhythmia, myocardial stunning and microvascular dysfunction ( 5 ). (spandidos-publications.com)
Reperfusion8
Stroke33
  • There are increasing evidences that show that the prognosis of patients with acute ischemic stroke (AIS) is closely related to the inflammatory response. (hindawi.com)
  • Acute ischemic stroke (AIS) is the most common type of stroke, accounting for 87% of all strokes [ 3 ]. (hindawi.com)
  • There is growing evidence that ischemic stroke is related to the systemic inflammatory response, and diverse inflammatory cytokines are being investigated as potential predictors of cardiovascular and functional prognosis after AIS [ 4 , 5 ]. (hindawi.com)
  • Inflammation plays a crucial role in the pathogenesis of ischemic stroke, with mechanisms of action including atherosclerosis, plaque instability, and plaque rupture triggering [ 7 , 8 ]. (hindawi.com)
  • In the case of an acute stroke, inadequate blood flow to the brain leads to an interruption in the supply of oxygen and glucose to the neurons, resulting in massive cell death within the infarcted core [ 9 ]. (hindawi.com)
  • A study reports high levels of CRP associated with clinical prognosis in the time window between 12 and 72 hours after ischemic stroke [ 17 , 18 ]. (hindawi.com)
  • AIS has different subtypes, and large artery atherosclerosis (LAA) is a key subtype of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification system. (hindawi.com)
  • Background: Ischemic stroke is a leading cause of morbidity and mortality. (researchsquare.com)
  • Therefore, this study aimed to further confirm the efficacy and safety of cinepazide maleate injection in patients with acute ischemic stroke. (researchsquare.com)
  • Methods: Patients with acute ischemic stroke were administered an intravenous infusion of 320 mg cinepazide maleate or placebo once daily for 14 days. (researchsquare.com)
  • Results: In total, 937 patients with an acute ischemic stroke were included, with a mean (standard deviation, SD) National Institutes of Health Stroke Scale score of 8.8 (2.4) and a mean (SD) stroke onset of 30.9 (11.4) hours prior. (researchsquare.com)
  • Conclusions: The results of this study show that cinepazide maleate injection is superior to placebo in improving neurological function and activities of daily living, reducing disability, and promoting functional recovery in patients with acute ischemic stroke. (researchsquare.com)
  • Ischemic stroke is an acute cerebrovascular event caused by decreased blood flow to the brain. (researchsquare.com)
  • Elevated troponin in acute ischemic stroke - a matter of debate? (eso-stroke.org)
  • With respect to high prognostic relevance, 1 international guidelines recommend the measurement of troponin in all patients presenting with acute ischemic stroke. (eso-stroke.org)
  • 2 However, high-sensitivity troponin is elevated in 20-55% of acute stroke patients, 3 many of whom without thrombotic acute coronary syndrome (ACS). (eso-stroke.org)
  • Why is troponin elevated in so many acute stroke patients? (eso-stroke.org)
  • 4 Beyond, elevated troponin in stroke patients might be attributable to nonischemic myocyte injury due to catecholamine-mediated myocardial toxicity, cytokine-mediated myocardial injury, endothelial dysfunction and microvascular spasms. (eso-stroke.org)
  • 5 Nonetheless, coronary culprit lesions were identified in 24% of stroke patients with elevated troponin, thus demonstrating that elevated troponin should not be ignored in acute stroke patients. (eso-stroke.org)
  • The recently launched Prediction of Acute Coronary Syndrome in Acute Ischemic Stroke (PRAISE) study aims to develop a diagnostic algorithm that allows the prediction of acute coronary syndrome in stroke patients with elevated troponin. (eso-stroke.org)
  • For the time being, a clear recommendation for acute stroke patients with elevated troponin is lacking. (eso-stroke.org)
  • So, elevated troponin in acute ischemic stroke remains a matter of debate! (eso-stroke.org)
  • 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. (eso-stroke.org)
  • Scheitz JF, Nolte CH, Laufs U, Endres M. Application and interpretation of high-sensitivity cardiac troponin assays in patients with acute ischemic stroke. (eso-stroke.org)
  • Jensen JK, Atar D, Mickley H. Mechanism of troponin elevations in patients with acute ischemic stroke. (eso-stroke.org)
  • Coronary Angiographic Findings in Acute Ischemic Stroke Patients With Elevated Cardiac Troponin: The Troponin Elevation in Acute Ischemic Stroke (TRELAS) Study. (eso-stroke.org)
  • Emergency departments play a critical role in the diagnosis and management of ischemic stroke and TIA. (cdc.gov)
  • A new NCHS report presents recent trends in visits to emergency departments for ischemic stroke or TIA. (cdc.gov)
  • From 2001 through 2011, the rate of emergency department visits for ischemic stroke or transient ischemic attack (TIA) decreased 35% for patients aged 18 and over and 51% for patients aged 55-74. (cdc.gov)
  • From 2004 through 2011, the percentage of emergency department visits for ischemic stroke or TIA in which the patient arrived by ambulance decreased 41% for patients under 75. (cdc.gov)
  • The percentage of emergency department visits for ischemic stroke or TIA in which a magnetic resonance imaging (MRI) or computed tomography (CT) test was ordered or provided increased 39% from 2001 through 2011. (cdc.gov)
  • The percentage of emergency department visits for ischemic stroke or TIA that resulted in admission or transfer to a hospital increased 10% from 2001 through 2011. (cdc.gov)
  • Geary L, Aronius J, Wettermark B, Hasselström J, Sjöborg B, von Euler M. Sociodemographic factors are associated with utilization of statins after ischemic stroke/TIA. (janusinfo.se)
Myocardium3
  • Importantly, the intensity of fluorescence and the magnitude of change in fluorescence intensity from a defined region of the myocardium is directly proportional to myocardial perfusion under controlled conditions. (medscape.com)
  • The modest prognostic benefit of an opened infarct-related artery may be realized even when recanalization is induced only 6 hours or later after the onset of symptoms, that is, when the salvaging of substantial amounts of jeopardized ischemic myocardium is no longer likely. (medscape.com)
  • Imaging evidence of new loss of viable myocardium or regional wall motion abnormality in a pattern consistent with an ischemic etiology. (who.int)
Perfusion5
  • The analysis of myocardial perfusion change is derived from the arterial and microvascular image data. (medscape.com)
  • Using this technology, it is possible to quantify the change in regional myocardial perfusion associated with the TVECA, in real time. (medscape.com)
  • Using a specific data acquisition protocol, this imaging technology and software compares regional myocardial perfusion before and after grafting, and quantifies the difference, if any, that results from the bypass graft (Figure 3). (medscape.com)
  • Myocardial salvage depends on the prompt, complete, and sustained restoration of myocardial perfusion. (bmj.com)
  • For the study, the researchers performed tests to measure the condition of cardiac tissue before and after an ischemic event and after perfusion was re-established. (prohealth.com)
Syndrome6
  • Despite major advances in the care of patients with acute coronary syndrome over many decades, rates of early morbidity and mortality associated with the condition remain unacceptably high. (mcw.edu)
  • Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) represents a current public health crisis. (springer.com)
  • The most common clinical manifestations of SARS-CoV-2 include fulminant pneumonia and acute respiratory distress syndrome (ARDS) [ 3 ]. (springer.com)
  • Several randomized, controlled trials have assessed the efficacy of the upstream administration of tirofiban (Platelet Receptor Inhibition for ischemic Syndrome Management in Patients Limited to very Unstable Signs and symptoms [PRISM-PLUS] regimen) in patients with non-ST-segment elevation acute coronary syndromes (ACS) (1,2) . (jacc.org)
  • Nowadays, it is still not possible to clinically distinguish whether an increase in high-sensitivity cardiac troponin (hs-cTn) values is due to myocardial injury or an acute coronary syndrome (ACS). (uninsubria.it)
  • Patients with this entity, although considered to be at low risk for acute coronary syndrome (ACS), nevertheless cause a great deal of stress to emergency care providers and have been considered "high risk" from a medical malpractice standpoint. (medscape.com)
Clinical3
  • Furthermore, it was suggested that a similar procedure may be implemented in a clinical setting, in order to maximize PI3K/Akt activation levels in patients with acute coronary artery disease. (spandidos-publications.com)
  • EGCG and zinc may therefore represent effective agents for use in the prevention of I/R injury in clinical practice. (spandidos-publications.com)
  • Associate Clinical Professor and Director of Acute Pain Service. (silverchair.com)
Remote ischaemic4
  • BACKGROUND: Remote ischaemic preconditioning attenuates cardiac injury at elective surgery and angioplasty. (ox.ac.uk)
  • INTERPRETATION: Remote ischaemic conditioning before hospital admission increases myocardial salvage, and has a favourable safety profile. (ox.ac.uk)
  • The purpose of this study is to determine whether Glyceryl Trinitrate (GTN) reduces injury to the heart during heart-lung bypass surgery in combination with the newer technique of remote ischaemic preconditioning (RIPC). (druglib.com)
  • Remote ischaemic preconditioning (RIPC) has been shown to reduce perioperative myocardial injury (PMI) in patients having CABG even when cold blood cardioplegia or intermittent cross clamp fibrillation is used as cardioprotective measures. (druglib.com)
Infarctions occur2
  • More than two thirds of myocardial infarctions occur in lesions that are less than 60% severe. (medscape.com)
  • In the US, about 1.0 million myocardial infarctions occur annually. (msdmanuals.com)
Tissue2
  • Ischemic injury occurs when the blood supply is insufficient to meet the tissue demand for metabolism. (medscape.com)
  • The poor outcome amongst these patients has been attributed to the effects of the restoration of blood flow to previously ischemic tissue ( 3 ). (spandidos-publications.com)
Troponin3
  • There is no increase in troponin T levels in skeletal muscle injury. (edu.pk)
  • The EMIT-test for Troponin T - a protein of the myocardial troponin complex - is nowadays of the great diagnostic value. (medline.ru)
  • Although initial creatinine kinase (CK) and CK-myocardial band were within the normal range, troponin-I was elevated to 0.130 ng/mL and N-terminal-pro hormone B-type natriuretic peptide was elevated to 1,859 pg/mL. (e-jnc.org)
Thrombotic3
  • In almost all patients, AMI is caused by an acute thrombotic coronary occlusion following the rupture of the cap of an atherosclerotic plaque. (bmj.com)
  • The PeriOperative Ischemic Evaluation (POISE)-3 Trial is a large international randomized controlled trial designed to determine if TXA is superior to placebo for the composite outcome of life-threatening, major, and critical organ bleeding, and non-inferior to placebo for the occurrence of major arterial and venous thrombotic events, at 30 days after randomization. (biomedcentral.com)
  • The use of tirofiban, when administered at HDB, is safe and significantly reduces the incidence of ischemic/thrombotic complications during high-risk PCI. (jacc.org)
Preconditioning1
  • Ischaemic postconditioning with a comparable sequence of brief periods of local ischaemia, when applied immediately after the ischaemic insult, confers benefits similar to preconditioning. (uea.ac.uk)
Inflammation2
  • There are many factors involved in the process of creating CECs, including: reduced interaction between the endothelial cells and basement membrane proteins, damaged endothelial cellular adhesion molecules, mechanical injury, decreased survival of cytoskeletal proteins, and inflammation. (wikipedia.org)
  • The term inflammatory cardiomyopathy (ICM) refers to a group of disorders for which an acute or chronic myocardial inflammation is the central cause of abnormal cardiac structure or impaired cardiac function. (intechopen.com)
Increases1
  • The heart can become damaged in COVID-19 by three distinct mechanisms: (i) the acute hyper-inflammatory response increases blood coagulability, which can cause blood clots that obstruct arteries and indirectly affect the heart. (springer.com)
Markers2
  • The impressive performance of CK, LDH and their respective isozymes did not stop investigators for searching better markers for myocardial damage. (edu.pk)
  • In addition, a significant decrease in the activities of myocardial injury markers i.e., creatine phosphokinase-MB (CK-MB isoenzyme) and lactate dehydrogenase (LDH) was also observed in the heart of ISP control group as compared to sham control. (scialert.net)
Strokes2
  • For such strokes (ischemic strokes), thrombolytics can be used to help dissolve the clot quickly. (medlineplus.gov)
  • About 87% of all strokes are ischemic strokes. (cdc.gov)
Complications1
  • We also review the cardiac complications of diphtheria and discuss how noninvasive bedside imaging technologies to monitor myocardial function and hemodynamic parameters can help improve the management of this neglected infectious disease. (cdc.gov)
Incidence2
  • The incidence of cardiac injury is much greater in patients with severe disease presentation and those in intensive care. (springer.com)
  • During the past year, COVID-19 patient mortality rates have improved due to tailored pharmacological treatments and patient management strategies that address the unique presentation of symptoms, which will hopefully also reduce the incidence of cardiac injury. (springer.com)
Diagnosis1
  • Diagnosis of acute skeletal muscle trauma (rhabdomyolysis) was made by obvious physical acute skeletal muscle injury diagnosed by attending casualty medical officer along with attending physician. (edu.pk)
Primary2
  • Epigallocatechin‑3‑gallate (EGCG), the predominant catechin component of green tea, has been reported to have potential cardioprotective effects in primary cultures of cardiac myocytes exposed to I/R injury, mediated through inhibition of signal transducers and activators of transcription‑1 activity. (spandidos-publications.com)
  • Schmidt-Mende K, Andersen M, Wettermark B, Hasselström J. Educational intervention on medication reviews aiming to reduce acute healthcare consumption in elderly patients with potentially inappropriate medicines -A pragmatic open-label cluster randomized controlled trial in primary care. (janusinfo.se)
Kidney1
  • No suspicion of acute kidney injury at least 12 hours after IV contrast agent administration (subjects who have undergone angiography) or after first medical contact for the index MI (subjects who have not undergone angiography). (who.int)
Symptoms1
  • Transient ischemic attacks (TIAs) cause similar symptoms, but the blockage of blood flow to the brain is temporary. (cdc.gov)
Coronary syndromes3
  • Загальні відомості про гострі коронарні синдроми (ГКС) Acute coronary syndromes result from acute obstruction of a coronary artery. (msdmanuals.com)
  • Серцеві маркери Acute coronary syndromes result from acute obstruction of a coronary artery. (msdmanuals.com)
  • In particular, in patients with acute coronary syndromes undergoing PCI, there is no evidence that tirofiban administered in the catheterization laboratory is superior to heparin alone. (jacc.org)
Cardiac muscle1
  • Trimetazidine (TMZ) is a cytoprotective drug that modifies cardiac muscle metabolism, to provide anti-ischemic benefits. (hindawi.com)
Abnormal1
  • If image quality is good and if the apex is visualized, the sensitivity and specificity of abnormal wall motion for diagnosing acute MI exceeds 90%, particularly in patients without previous MI. (medscape.com)
Protects1
  • To the best of our knowledge, the current study was the first to demonstrate that EGCG + Zn2+ protects H9c2 cells against H/R injury through activation of the PI3K/Akt pathway, as determined by western blotting. (spandidos-publications.com)
Mortality1
  • Ischaemic heart disease is a leading cause of mortality in the western world. (druglib.com)
Damage2
  • Researchers are hoping that the HD-CEC test will be used to predict cardiovascular diseases such as acute MI, angina and heart failure and analyze vascular damage. (wikipedia.org)
  • Through this mechanism, TMZ is thought to correct disturbances in myocardial cellular homeostasis that result from acute ischemic damage and to protect against cardiomyocyte injury [ 14 , 15 ]. (hindawi.com)
Treatment7
  • In this study, we determined whether similar salutary effects are achieved with acute treatment with troglitazone. (diabetesjournals.org)
  • The plant Tribulus terrestris Linn, a deciduous tree of the Zygophyllaceae family, is an important herb from Indian and Chinese traditional medicine literature for the treatment of various diseases especially ischemic heart diseases (Warrier, 1994). (scialert.net)
  • Imaging is also useful in detecting pericardial effusion, concomitant valvular or congenital heart disease, and marked depression of ventricular function that may interdict treatment in the acute phase with beta-adrenergic blockers. (medscape.com)
  • This review focuses on direct and indirect causes of myocardial injury in COVID-19 patients and highlights current knowledge, treatment strategies, and outstanding questions in the field. (springer.com)
  • A previous study identified that in vivo treatment with EGCG reduced I/R injury by inhibiting the nuclear factor-κB and activator protein 1 pathways in rat hearts ( 11 ). (spandidos-publications.com)
  • A number of patients undergo coronary artery bypass graft (CABG) surgery as treatment for ischaemic heart disease. (druglib.com)
  • If the ECG clearly shows an injury or ischemic pattern, the patient is admitted to the hospital for an urgent workup and treatment. (medscape.com)
Dysfunction1
  • Cardiac cells that survive this first wave of injuries will often have their mitochondrial functions compromised, and this can lead to further dysfunction and even cellular death. (prohealth.com)