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  • clinical
  • Disease can be reversed in many patients, and thus clinical management focuses upon the identification and treatment of the precipitant while providing multiorgan-supportive care that addresses the complex pattern of physiological disturbance in critically ill patients with liver disease. (readbyqxmd.com)
  • deterioration
  • Acute liver failure is an uncommon condition in which rapid deterioration of liver function results in coagulopathy, usually with an international normalized ratio (INR) of greater than 1.5, and alteration in the mental status (encephalopathy) of a previously healthy individual. (medscape.com)
  • high mortality
  • Acute liver failure often affects young people and carries a very high mortality. (medscape.com)
  • Recognition of acute-on-chronic liver failure as a clinically and pathophysiologically distinct syndrome with defined diagnostic and prognostic criteria will help to encourage the development of new management pathways and interventions to address the unacceptably high mortality. (readbyqxmd.com)
  • develops
  • Acute liver failure occurs when a previously healthy animal rapidly develops a liver that fails to work. (uk.net)
  • If your pet develops acute liver failure, we will discuss the treatment options in detail with you and give you the help you need in making decisions about what you wish us to do to help your pet. (uk.net)
  • patient
  • Because the vital functions of the liver can be lost over a very short period the patient can deteriorate fast, needing treatment within hours or days. (uk.net)
  • patient's
  • Liver failure is diagnosed after careful consideration of the patient's history, a full physical examination and by carrying out blood and urine tests which indicate dysfunction of the liver. (uk.net)
  • organs
  • The liver is very good at regenerating itself (unlike other organs such as the kidneys), but serious damage to the liver can cause a rapid failure of its function - this is known as acute liver failure. (uk.net)
  • The gut microbiota has the capacity to produce a diverse range of compounds that play a major role in regulating the activity of distal organs and the liver is strategically positioned downstream of the gut. (readbyqxmd.com)