Acute diabetic ketoacidosis. Medical search. Frequent questions

DKA, a life-threatening complication of diabetes, is characterized by the triad of hyperglycemia, metabolic acidosis, and ketoacidosis. (uspharmacist.com)
These modules focused on diabetic ketoacidosis (a severe, life-threatening complication of diabetes), how to treat patients who were just diagnosed with diabetes, and how to recognize and treat complications of diabetes. (usda.gov)
In 1996, 5-year-old Shay Maurin tragically died of acute diabetic ketoacidosis , a life-threatening complication of diabetes. (lexblog.com)

Diabetic ketoacidosis is an acute complication of diabetes that occurs mostly in type 1 diabetes mellitus. (msdmanuals.com)

Ketoacidosis is a metabolic condition that occurs as a result of an insufficient amount of insulin. (ascls.org)
Euglycemic diabetic ketoacidosis (EDKA) is a rare, acute, life-threatening emergency that is characterized by euglycemia, metabolic acidosis, and ketoacidosis. (uspharmacist.com)
however, approximately 2.6% to 3.2% of DKA admissions are cases of EDKA, in which metabolic acidosis and ketoacidosis are accompanied by euglycemia. (uspharmacist.com)
Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. (nih.gov)
Strength training helps to prevent diabetes mellitus: Diabetic Mellitus is a metabolic disorder, in which there is hyperglycemia, also known as high blood sugar, over a long time. (checkbiotech.org)
Patients of physicians with high empathy scores, compared with patients of physicians with moderate and low empathy scores, had a significantly lower rate of acute metabolic complications. (familydocs.org)
05). Logistic regression analysis showed physicians' empathy scores were associated with acute metabolic complications: odds ratio (OR) = 0.59 (95% confidence interval [CI], 0.37-0.95, contrasting physicians with high and low empathy scores). (familydocs.org)
Patients' age (≥69 years) also contributed to the prediction of acute metabolic complications: OR = 1.7 (95% CI, 1.2-1.4). (familydocs.org)
Physicians' gender and age, patients' gender, type of practice (solo, association), geographical location practice (mountain, hills, plain), and length of time the patient had been enrolled with the physician were not associated with acute metabolic complications. (familydocs.org)
Hale PJ, Crase J, Nattrass M. Metabolic effects of bicarbonate in the treatment of diabetic ketoacidosis. (pharm-so-hard.com)

4 However, euglycemic diabetic ketoacidosis (EDKA) has emerged as a rare but serious adverse effect associated with SGLT2i. (uspharmacist.com)
Euglycemic diabetic ketoacidosis (EDKA) is a potentially life-threatening condition and a reported side effect of antidiabetic sodium-glucose-cotransporter-2-inhibitors (SGLT2-I). The analysis of the herein presented case and its management formed the incentive to prepare this multidisciplinary work and includes an overview about perioperative SGLT2-I-induced ketoacidosis. (frontiersin.org)
A PubMed search on relevant entries was conducted combining the terms "euglycemic diabetic ketoacidosis" AND "surgery. (frontiersin.org)
Besides urinary tract and genital infections, one major adverse effect is the so-called euglycemic diabetic ketoacidosis (EDKA), which requires close attention ( 22 - 24 ). (frontiersin.org)

There are Acute complications- Examples of diabetes mellitus includes the following diabetic ketoacidosis, hyperosmolar hyperglycemic state. (checkbiotech.org)

Physical findings in dogs with acute pancreatitis are very variable, ranging from depression, to mild dehydration with signs of abdominal pain, to acute abdominal crisis, shock (tachycardia, prolonged capillary refill time, tacky mucous membranes, hypothermia), petechiation, icterus and ascites. (ivis.org)
With severe dehydration, potassium levels may be elevated (eg, congenital adrenal hyperplasia , acute kidney injury) or low (eg, pyloric stenosis, alkalosis). (medscape.com)
This agent is used for resuscitation and for dehydration associated with diabetic ketoacidosis. (medscape.com)

Diabetic ketoacidosis (DKA) is a medically fatal condition in poorly controlled hyperglycemia or newly diagnosed diabetes mellitus. (e-apem.org)

That's a great question because although we don't know all the mechanisms that probably lead to the chronic benefits, for acute efficacy, we looked at the benefits across diuresis, natriuresis, and diuretic response, looking for any additive benefit acutely for a diuretic decongestive outcome and then safety across all the other outcomes. (medscape.com)
Chronic complications- Include the following conditions diabetic foot ulcer, neuropathies such as a feeling of tingling in the foot and the hand, retinopathy, stroke in severe cases, coronary heart diseases and generally cardiovascular problems. (checkbiotech.org)

Liver from a 62-year-old woman (lung transplant patient) cerebrospinal fl uid (CSF) collected from the right kidney showing acute necrosis of hepatocytes and minimal infl ammation. (cdc.gov)
Patients with COVID-19 had a three times higher rate of acute kidney injury during an episode of DKA, at 30% versus 10% among those without COVID-19, the authors reported. (medpagetoday.com)
Complications include hypoglycemia, acute kidney injury, cardiac arrthymias and cerebral injury. (novabiomedical.com)
They solicited answers to questions on the manner(s) by which they care for pediatric patients who have developed severe acute kidney injury (AKI). (medscape.com)
Predicting the risk factors of diabetic ketoacidosis-associated acute kidney injury: A machine learning approach using XGBoost. (cdc.gov)

Alcoholic Ketoacidosis Alcoholic ketoacidosis is a complication of alcohol use and starvation that causes excess acid in the bloodstream, resulting in vomiting and abdominal pain. (msdmanuals.com)

Severe hypertriglyceridemia (HTG) is an uncommon complication of DKA and can be associated with acute pancreatitis (AP). (e-apem.org)
1,000 mg/dL) is an uncommon complication of DKA and can be associated with acute pancreatitis (AP) [ 2 ]. (e-apem.org)

The main exclusion criteria were type 1 diabetes, systolic blood pressure less than 90 mmHg, serum glucose less than 80 mg/dL, use of IV inotropic therapy, and history of diabetic ketoacidosis. (news-medical.net)

Diabetic ketoacidosis (DKA) is the most common hyperglycemic emergency and causes the greatest risk for death in patients with diabetes mellitus. (lww.com)

Diabetes can directly cause acute life-threatening events, such as diabetic ketoacidosis* and hyperosmolar nonketotic coma. (bumrungrad.com)
Remark: *Diabetic ketoacidosis and hyperosmolar nonketotic coma are medical conditions that can result from very high glucose level and biochemical imbalance in uncontrolled diabetes. (bumrungrad.com)
Participating physicians' Jefferson Scale of Empathy scores were compared with occurrence of acute complications (hyperosmolar state, diabetic ketoacidosis, coma) in diabetes patients hospitalized in 2009. (familydocs.org)
Without treatment, diabetic ketoacidosis can progress to coma and death. (msdmanuals.com)

30 days after infection than were those without COVID-19 and those with prepandemic acute respiratory infections. (cdc.gov)
If left untreated, diabetic ketoacidosis can lead to more serious complications including circulatory collapse, decreased blood potassium levels, infection and cerebral edema. (ascls.org)
The following case study presents a complex condition of ketoacidosis associated with a bacterial infection compounded by the patient's history of alcohol abuse. (ascls.org)
Produced in high levels during periods of stress, infection, etc possibly leading to diabetic ketoacidosis, a very serious condition. (wikipedia.org)

Potassium chloride is commonly administered in electrolyte replacement therapy for diabetic ketoacidosis. (medscape.com)

A case of fulminant type 1 diabetes associated with acute renal failure. (nel.edu)
A 56-year-old man suffered from severe diabetic ketoacidosis which was complicated by acute renal failure and rhabdomyolysis. (nel.edu)
Deng D, Xia L, Chen M, Xu M, Wang Y, Wang C. A case of fulminant type 1 diabetes associated with acute renal failure. (nel.edu)
He was admitted to the surgical intensive care unit of the CHRU La Cavale Blanche of Brest on 12 September, 2015 for decompensated diabetic ketoacidosis, acute renal failure and hemolytic anemia. (scirp.org)

Clinical efficacy of dexamethasone on diabetic ketoacidosis complicated with acute pancreatitis: A randomized controlled study. (bvsalud.org)
This study aimed to provide a clinical basis for the therapy of diabetic ketoacidosis (DKA) complicated with acute pancreatitis (AP) through exploring the clinical efficacy of dexamethasone . (bvsalud.org)
A diagnosis of acute pancreatitis is based on a combination of compatible clinical, clinicopathological and imaging findings. (ivis.org)
Proteinuria occurs in some dogs with acute pancreatitis, possibly as a consequence of pancreatic enzyme-mediated glomerular damage, and is usually transient. (ivis.org)

There have been concerns that it may not be safe and concerns that there may be increased risk for hypoglycemia or ketoacidosis in an acute hospital setting. (medscape.com)
Early dapagliflozin initiation was safe across all diabetic and cardiorenal in-hospital outcomes, with no differences between treatment groups in the change in eGFR from baseline to end-of-study, incidence of adverse events, inpatient mortality, symptomatic hypotension, total or serious hypoglycemia events, genitourinary infections, or severe hypokalemia. (news-medical.net)

Symptoms of diabetic ketoacidosis include nausea, vomiting, abdominal pain, and a characteristic fruity odor on the breath. (msdmanuals.com)

Diabetic patients, especially those on insulin, may not recognize symptoms as DKA because the serum glucose is not elevated. (uspharmacist.com)
Unspecific symptoms mimicking acute abdomen and normoglycemia can lead to delayed diagnosis of EDKA and might harm patients under SGLT2-I therapy in the perioperative setting. (frontiersin.org)
Furthermore, a correct diagnosis can be difficult and delayed when ketoacidosis presents with unspecific symptoms, such as the picture of an "acute abdomen" ( 1 , 2 ). (frontiersin.org)
The condition of acute abdomen describes many complex symptoms, usually dominated by severe pain and elevated tension (defense) of the abdominal wall. (frontiersin.org)
Improvement in symptoms and quality of life of heart failure patients admitted with acute decompensation. (who.int)

Increases in the number of type 1 diabetes diagnoses ( 1 , 2 ) and increased frequency and severity of diabetic ketoacidosis (DKA) at the time of diabetes diagnosis ( 3 ) have been reported in European pediatric populations during the COVID-19 pandemic. (cdc.gov)
Diabetic ketoacidosis (DKA) is frequently present at diagnosis of type 1 diabetes, with younger children, especially those less than 2 years-old, at higher risk. (novabiomedical.com)

Ketoacidosis is a severe complication in people who have diabetes. (healthline.com)

Intravenous sodium bicarbonate therapy in severely acidotic diabetic ketoacidosis. (pharm-so-hard.com)
Intravenous insulin is probably the safest and most effective method for treating severe diabetic ketoacidosis. (medscape.com)

Chua HR, Schneider A, and Bellomo R. Bicarbonate in diabetic ketoacidosis - a systematic review. (pharm-so-hard.com)

Diabetic ketoacidosis (DKA) in children is defined as a blood glucose level over 11 mmol/L, venous pH below 7.3 or serum bicarbonate level below 15 mmol/L, and either the presence of ketonemia (blood β-hydroxybutyrate level ≥ 3 mmol/L) or moderate to high ketonuria. (medscape.com)
Bicarbonate therapy in severe diabetic ketoacidosis. (pharm-so-hard.com)
Okuda Y, Adrogue HJ, Field JB, Nohara H, Yamashita K. Counterproductive effects of sodium bicarbonate in diabetic ketoacidosis. (pharm-so-hard.com)

As previously mentioned, continuous, low-dose IV insulin infusion is generally accepted as the safest and most effective method of insulin delivery for treating diabetic ketoacidosis. (medscape.com)

Rigolon R, Fossà I, Rodella L, Targher G. Black esophagus syndrome associated with diabetic ketoacidosis. (wjgnet.com)

Early initiation of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin did not result in a statistically significant improvement in diuretic efficiency relative to structured usual care in hospitalized patients with acute decompensated heart failure (ADHF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023. (news-medical.net)
the study drug( dapagliflozin) will be prescribed as add on therapy to the conventional treatment of acute heart failure in a 1:1. (who.int)

She has authored guidelines for the management of pediatric patients presenting with acute appendicitis, asthma exacerbations, diabetic ketoacidosis, head trauma, and sepsis. (umaryland.edu)

However, what we didn't know was that when starting it acutely on the first day of heart failure hospitalization, (1) does it provide any acute efficacy, and (2) is it safe ? (medscape.com)
The two primary therapeutic goals during acute decompensated heart failure hospitalization are complete decongestion and optimization of GDMT. (news-medical.net)

Beta-Hydroxybutyrate (BHB) is the most common ketone body produced in the body and increases during states of ketosis and ketoacidosis. (novabiomedical.com)

Diabetic retinopathy causes from 12,000 to 24,000 new cases of blindness each year. (bumrungrad.com)
Economic Evaluation of Artificial Intelligence Systems Versus Manual Screening for Diabetic Retinopathy in the United States. (cdc.gov)

We're terrible at acute decompensation. (medscape.com)

Topics included diabetic ketoacidosis, new-onset diabetes management, and acute complications of diabetes. (usda.gov)

The cornerstones of diabetic ketoacidosis management are fluid resuscitation, insulin administration, electrolyte monitoring and administration, and close observation to minimize the effects of cerebral edema. (medscape.com)
Results from a prospective study of diabetic ketoacidosis suggested the risk of cerebral edema was higher in those who received immediate insulin treatment and starting insulin infusion one hour after fluid resuscitation has begun is suggested. (medscape.com)

Ketoacidosis that occurs in people with diabetes is called diabetic ketoacidosis. (msdmanuals.com)

When we looked at the space of acute heart failure, as you just laid out, we know that starting an SGLT2 inhibitor in the ambulatory setting or at hospital discharge and continuing it chronically has widespread benefit across patients, regardless of ejection fraction. (medscape.com)
Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. (springermedizin.de)
Blockages during the pandemic compromised thodology were followed: (1) definition and the regular follow-up of diabetic patients, putting alignment of objectives and questions, (2) de- their glycemic control at risk and compromising velopment and alignment of the inclusion criteria their self-care. (bvsalud.org)

Diabetic ketoacidosis is diagnosed by blood tests that show high levels of glucose, ketones, and acid. (msdmanuals.com)
Ketones provide some energy to cells but also make the blood too acidic (ketoacidosis). (msdmanuals.com)

It can sometimes be smelled on the breath of those in, or about to enter diabetic ketoacidosis as a fruity (nail polish remover, or lacquer thinner) sort of smell. (wikipedia.org)

A new article in the Journal of Clinical Endocrinology & Metabolism ( JCEM ) addresses unique concerns and considerations regarding diabetic ketoacidosis (DKA) in the setting of COVID-19. (medscape.com)

Frequent, small subcutaneous doses of insulin lispro or insulin aspart have been used successfully to treat milder cases of diabetic ketoacidosis in which oral fluid replacement is possible. (medscape.com)

We report a survival case of invasive splenic mucormycosis involving the liver caused by Rhizopus microsporus in a patient during consolidation therapy for acute monocytic leukemia (AML-M 5 ). (frontiersin.org)

This is a short-acting form of insulin traditionally used in the management of diabetic ketoacidosis, as it may be used intravenously. (medscape.com)

SGLT2i in Acute Heart Failure, The Earlier The Better? (medscape.com)
SGLT2 Inhibitors in Acute Heart Failure, The Earlier The Better? (medscape.com)
Tell me, why did we think a sodium-glucose cotransporter 2 (SGLT2) [inhibitor] would do anything in acute heart failure? (medscape.com)

Diabetes itself does not cause changes in personality or psychiatric illness, but particular subgroups of the diabetic population appear to be at risk for developing psychosocial problems. (cdc.gov)

A total of 33 articles on SGLT2-I-induced ketoacidosis in the context of surgical treatment were identified. (frontiersin.org)
Insulin is the only treatment that addresses the cause of diabetic ketoacidosis. (medscape.com)

Diseases12

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Health Care1

Life-threatening complication3

Complication of diabetes1

Metabolic10

Euglycemic diabetic ketoacidosis4

Hyperosmolar hyperglycemic state1

Dehydration3

Controlled hyperglycemia1

Chronic2

Kidney5

Alcoholic ketoacidosis1

Associated with acute pancreatitis2

History of diabetic1

Hyperglycemic1

Coma4

Infection4

Potassium1

Renal4

Pancreatitis4

Hypoglycemia2

Include nausea1

Symptoms5

Diagnosis2

Severe complication1

Intravenous2

Systematic review1

Bicarbonate3

Safest and most effective1

Black Esophagus1

Dapagliflozin2

Pediatric patients1

Hospitalization2

Ketosis1

Retinopathy2

Decompensation1

Diabetes management1

Resuscitation2

People with diabetes1

Patients3

Ketones2

Fruity1

Endocrinology1

Fluid1

Therapy1

Management1

Heart failure3

Illness1

Treatment2