• This surgical procedure includes deep hypothermic circulatory arrest, which involves cooling the body to induce hypothermia. (realinvestplan.com)
  • Deep hypothermic circulatory arrest (DHCA) is a surgical technique in which the temperature of the body falls significantly (between 20 °C (68 °F) to 25 °C (77 °F))and blood circulation is stopped for up to one hour. (wikipedia.org)
  • Cardiopulmonary bypass machines were essential to the development of deep hypothermic circulatory arrest (DHCA) in humans. (wikipedia.org)
  • To accomplish this goal, cardiopulmonary bypass (CPB), often coupled with either deep hypothermic circulatory arrest (DHCA) or antegrade cerebral perfusion (ACP), is usually required. (medscape.com)
  • Using a clinically relevant model of surgical deep hypothermic circulatory arrest (DHCA) combined with targeted metabolomic and proteomic profiling, we are investigating how changes in hibernation-specific myocardial expression/activity of PPARα nuclear receptor and downstream target genes (FGF21) following cardiac surgery can provide cardioprotection by increasing myocardial fatty acid oxidation and inhibiting NF-κB regulated pro-inflammatory responses. (duke.edu)
  • The studied recommended to start hypothermia as soon as possible on arrival and they demonstrated a poor outcome in patients who arrived hypothermic and then enrolled into the normothermic group with early active rewarming. (criticalcareindia.com)
  • In recent years various techniques have been inspired and refined to reduce the duration and risk of visceral ischemia such as mild, moderate, or deep hypothermic repair with left heart bypass, or complete or partial cardiopulmonary bypass combined with selective perfusions to vital viscera, the lower extremities and the spinal cord. (authorea.com)
  • Young age, myocardial infarction, and potentially reversible causes of cardiac arrest such as hypothermia and pulmonary emboli predict a favorable result, especially when the arrest is witnessed and followed by prompt and good resuscitative efforts. (hindawi.com)
  • In one large study, the overall median duration of resuscitation for in-hospital cardiac arrest was 17 minutes with an interquartile range of 10-26 min [ 3 ]. (hindawi.com)
  • The current overall survival rate to hospital discharge is 17% for in-hospital cardiac arrest and 5% for out-of-hospital cardiac arrest [ 5 , 6 ]. (hindawi.com)
  • We feel that developing strategies to help 'switch' myocardial metabolism to resemble that naturally occurring in mammalian hibernators represents a transformative approach that could ultimately have an important positive impact in patients undergoing cardiac surgery and transplantation, as well as in victims of cardiac arrest, stroke, trauma and hypothermia, in addition to fundamentally advancing the field of nuclear receptor biology and myocardial substrate metabolism under extremes of physiology. (duke.edu)
  • Analgesia, sedation, and neuromuscular blockade during targeted temperature management after cardiac arrest. (mainehealth.org)
  • In addition, bradycardia also can develop in class IV, shortly before cardiac arrest. (reliasmedia.com)
  • Cardiogenic shock is a rare cause of shock in trauma unless the patient experienced a blunt cardiac injury (BCI), the trauma was precipitated by a heart attack, or the trauma itself caused a stress-induced cardiomyopathy. (reliasmedia.com)
  • The Use of Extracorporeal Life Support (ECLS) in Sudden Cardiac Death -- 17 Hypothermia Therapy in Sudden Death -- 18. (nshealth.ca)
  • During cardiac arrest, if an I.V. route is unavailable, epinephrine can be administered endotracheally. (rnpedia.com)
  • For a patient in cardiac arrest, the first priority is to establish an airway. (rnpedia.com)
  • In severe hypothermia, extracorporeal membrane oxygenation (ECMO) or cardiopulmonary bypass may be useful. (theinfolist.com)
  • His clinical focus is the surgical treatment of end-stage cardiopulmonary failure, including heart transplant, heart-lung transplant, lung transplant, mechanical circulatory support (MCS), and extracorporeal membrane oxygenation (ECMO). (stanford.edu)
  • Morales DLS, Lorts A, Greenberg JW, Reagor JA, Ündar A. Highlights of the Sixteenth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. (ispmcs.org)
  • Ündar A. Impact of the Sixteen International Conferences on pediatric mechanical circulatory support systems and pediatric cardiopulmonary bypass procedures in congenital heart surgery patients. (ispmcs.org)
  • Law S, Chai P, Ündar A. Outcomes of the Fifteenth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. (ispmcs.org)
  • Thangappan K, Barnes A, Lorts A, Morales DLS, Ündar A. Welcome to the sixteenth international conference on pediatric mechanical circulatory support systems and pediatric cardiopulmonary perfusion [Guest editorial]. (ispmcs.org)
  • This book summarizes the occurrence of SD, especially in specific groups (such as women, young and middle-aged groups), its causes, predisposing factors, lifestyle, morbidity, point of care testing, and advanced treatment methods including extra-corporeal membrane oxygenation, cardiopulmonary resuscitation and hypothermia treatment. (nshealth.ca)
  • The origin of hypothermia and neuroprotection was also observed in infants who were exposed to cold due to abandonment and the prolonged viability of these infants. (wikipedia.org)
  • This report describes the role of neuroprotection in acute disorders such as stroke and injuries of the nervous system as well as in chronic diseases such as neurodegenerative disorders because many of the underlying mechanisms of damage to neural tissues are similar in all these conditions and several products are used in more than one disorder. (researchandmarkets.com)
  • Singapore, 27th Oct 2023, King NewsWire - Acute aortic syndrome is a collection of life-threatening aortic conditions that demand immediate medical attention, encompassing aortic dissection, aortic intramural hematoma, leaking aortic aneurysms, and penetrating atherosclerotic ulcers. (realinvestplan.com)
  • Acute aortic syndrome is an umbrella term for several aortic diseases, including aortic dissection, aortic intramural hematoma, leaking aortic aneurysms, and penetrating atherosclerotic ulcers. (realinvestplan.com)
  • One of the hallmark symptoms of acute aortic syndrome is an acute tearing chest pain, which may radiate to the back. (realinvestplan.com)
  • For cases of acute aortic syndrome involving the ascending aorta, emergency high-risk open surgery is the preferred treatment. (realinvestplan.com)
  • For acute aortic syndrome that spares the ascending aorta, patients may be treated with medical therapy. (realinvestplan.com)
  • In conclusion, acute aortic syndrome comprises a range of life-threatening aortic conditions, each with distinct clinical presentations, diagnostic methods, and treatment options. (realinvestplan.com)
  • The only heart surgeries that continued to require total circulatory arrest were repairs to the aortic arch. (wikipedia.org)
  • PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. (bvsalud.org)
  • Postoperative hypoxemia in acute type A aortic dissection (AADA) is a common complication and is associated with negative outcomes. (biomedcentral.com)
  • Acute type A aortic dissection (AADA) is a fatal condition. (biomedcentral.com)
  • Dr. Coselli is an innovator and a leader in his field and he is highly experienced in complex aortic repair, such as repair performed in patients with connective tissue disorders (such as Marfan and Loeys-Dietz syndromes), as well as emergent repair performed in patients with conditions such as acute aortic dissection or aortic rupture. (bcm.edu)
  • Since there is no randomized trials that have evaluated the duration of resuscitation and the bulk of information regarding the duration of resuscitation in various conditions such as hypothermia relies on case series and expert opinion, we reviewed all reported cases of prolonged resuscitation in the English literature. (hindawi.com)
  • To reduce morbidity and mortality as a result of uncontrolled hemorrhage, patients needing a massive transfusion, specifically addressed in detail later in this chapter, must be quickly identified so that immediate interventions can prevent the development of the lethal triad of coagulopathy, hypothermia, and acidosis. (medscape.com)
  • Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator that has long been used in the management of acute respiratory distress syndrome (ARDS), pulmonary hypertension, neonatal hypoxemic respiratory failure, and lung transplantations. (biomedcentral.com)
  • 10-year outcomes after acute ST-elevation myocardial infarction treated with primary percutaneous coronary intervention - single center experience. (kardio.hr)
  • Clinical outcomes of atrial fibrillation and acute myocardial infarction in long-term follow up. (kardio.hr)
  • Patients presenting with acute myocardial infarction and no apparent cardiovascular risk factors: are they wolves in sheep's clothing? (kardio.hr)
  • Protective effect of electrolyzed reduced water on the paraquat-induced oxidative damage of human lymphocyte DNA. (h2bev.com)
  • Up-regulation of P-glycoprotein expression by means of glutathione depletion- induced oxidative stress in rat brains microvessel endotelial cells. (fosite.ru)
  • AHNAK2 participates in the stress-induced nonclassical FGF1 secretion pathway. (mainehealth.org)
  • In addition to reperfusion therapy, the critical care management of patients with an acute ischemic stroke also includes airway and ventilation management, hemodynamic management, glucose control, anticoagulation management, and surgery in select cases. (umaryland.edu)
  • Acute ischaemic stroke: challenges for the intensivist. (umaryland.edu)
  • Induced hypertension, hypervolemia, and hemodilution (ie, "triple-H therapy") aimed to maintain adequate cerebral perfusion pressure in the setting of impaired cerebrovascular autoregulation. (medscape.com)
  • 129 Chapter VH3 (by O.H.G. Wilder-Smith) Basic Physiology and Acute Therapy. (sermon-online.com)
  • Severe hypercalcemia can be treated by acute hemodialysis and discontinuing Vitiron Suscaps (Calcium) acetate therapy. (sdrugs.com)
  • Effect of Steady Hypothermia and Normothermia on Multimodality Evoked Potentials in Human PoikilothermiaMarius A. MacKenzie, Dick M. Vingerhoets, Ernst J. Colon, Alfred J. L. G. (neuraxismed.com)
  • Included 392 patients and enrolled to hypothermia (33℃) or normothermia for 48 hours. (criticalcareindia.com)
  • Unique to this study, patients in the hypothermia group displayed higher ICPs than patients in the normothermia group. (criticalcareindia.com)
  • Liu etal in 2006 reported no difference in outcome with selective brain cooling to moderate hypothermia but the outcome was poor with normothermia. (criticalcareindia.com)
  • Pitfalls in the diagnosis of the acute coronary syndrome in hemodialysis patients. (kardio.hr)
  • Patients in the older group had higher incidence of dialysis for acute kidney injury and longer ICU stay compared with those in the younger group. (bvsalud.org)
  • For out-of-hospital arrest, the National Association of Emergency Medical Services Physicians suggest that resuscitative efforts could be terminated in patients who do not respond to at least 20 minutes of advanced life support care [ 4 ]. (hindawi.com)
  • Biventricular Impella use in pediatric patients with severe graft dysfunction from acute rejection after heart transplantation. (ispmcs.org)
  • Subgroup analysis demonstrated that prophylactic hypothermia had a better outcome when applied to patients who had surgical evacuation of hematoma. (criticalcareindia.com)
  • In the sec- ond arm of the look at, after a median 23-month consolidation, 87 % of patients accomplished rise 3 or 4 acute toxicities and 20 % knowledgeable downgrade pass 3 or 4 unpunctual toxicities 4]. (fosite.ru)
  • Hibernators such as arctic ground squirrels (AGS) depress their metabolic, heart, and respiratory rates as well as their core body temperature to enter a state called torpor during which they exhibit remarkable resistance to myocardial I/R injury and ventricular dysrhythmias normally associated with hypothermia. (duke.edu)
  • The primary outcome will be the differences between groups in myocardial protection in biochemical terms (ie, perioperative troponin levels) and clinical terms (ie, presence of the composite variable acute cardiovascular event ). (researchprotocols.org)
  • Intraoperative tissue hypoperfusion and re-reperfusion injury, which generate reactive oxygen species (ROS), are suggested to induce delirium. (mdpi.com)
  • At 2-yr follow-up, 3.8% of survivors of an acute pulmonary embolic event develop chronic thromboembolic pulmonary hypertension (CTEPH) defined as a persistent mean pulmonary arterial pressure greater than 25 mmHg for 6 months after the inciting event. (silverchair.com)
  • The use of hypothermia for medical purposes dates back to Hippocrates, who advocated packing snow and ice into wounds to reduce hemorrhage. (wikipedia.org)
  • Hemorrhagic shock is defined as an acute loss of circulating blood volume leading to inadequate oxygen delivery to tissues. (reliasmedia.com)
  • A case of possible iatrogenic ketamine-Induced mania in a patient being treated for postoperative pain. (mainehealth.org)
  • Tranexamic acid may decrease mortality from severe trauma but needs to be given within three hours of the acute trauma. (reliasmedia.com)
  • There were acute kidney dysfunction in 3 cases, and pulmonary haemorrhage in 1 case. (bvsalud.org)
  • By 1959, it was known from the animal experiments of Bigelow, Andjus and Smith, Gollan, Lewis's colleague, Niazi, and others that temperatures near 0 °C could be survived by mammals, and that colder temperature permitted the brain to survive longer circulatory arrest times, even beyond one hour. (wikipedia.org)
  • This can begin circulatory arrest before the brain has reached a safe temperature. (wikipedia.org)
  • paradoxical undressing Hypothermia is defined as a body core temperature below in humans. (theinfolist.com)
  • Hypothermia may be diagnosed based on either a person's symptoms in the presence of risk factors or by measuring a person's core temperature. (theinfolist.com)
  • Another classification system, the Swiss staging system, divides hypothermia based on the presenting symptoms which is preferred when it is not possible to determine an accurate core temperature. (theinfolist.com)
  • Thus immersion (in cold water) may lead to hypothermia, year from 2005 to 2014, plus an additional 679 boating- and submersion at any water temperature may lead to related deaths, 75% of which were from d rowning.5,6 drowning. (bvsalud.org)
  • There is an increased incidence of brain injury at times longer than 40 minutes, but sometimes circulatory arrest for up to 60 minutes is used if life-saving surgery requires it. (wikipedia.org)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • Acute massive pulmonary embolism was suspected. (hindawi.com)
  • Acute coronary syndrome due to suspected fibromuscular dysplasia - a case report. (kardio.hr)
  • Kounis syndrome: acute coronary syndrome caused by hornet sting: a case report. (kardio.hr)
  • A comparison of usual care, a patient-centred education intervention and motivational interviewing to improve medication adherence and readmissions of adults in an acute-care setting. (mainehealth.org)
  • Abstracts for as part of a review and evaluation of literature regarding which the full article could not be obtained were acute care for the drowning patient, in both out-of- excluded. (bvsalud.org)
  • The Wilderness Medical Society convened a panel to review available evidence supporting practices for acute management and treatment of drowning in out-of-hospital and emergency medical care settings. (bvsalud.org)
  • The first heart surgery using hypothermia to provide a longer time that blood circulation through the whole body could be safely stopped was performed by F. John Lewis and Mansur Taufic at the University of Minnesota in 1952. (wikipedia.org)
  • Thereafter, the only surgeries that required stopping blood circulation to the whole body ("total circulatory arrest") were surgeries involving blood supply to the brain. (wikipedia.org)
  • Humans had survived cooling to 9 °C, and circulatory arrest of 45 minutes, using external cooling only. (wikipedia.org)
  • In this procedure, the first successful open heart surgery, Lewis repaired an atrial septal defect in a 5-year-old girl during 5 minutes of total circulatory arrest at 28 °C. Many similar procedures were performed by Soviet heart surgeon, Eugene Meshalkin, in Novosibirsk during the 1960s. (wikipedia.org)
  • Multiple approaches in recent years have been implemented to address the persistent shortage of heart donors, including a recent modification of UNOS heart allocation system, expanding donor acceptance criteria, and adoption of novel techniques to utilize hearts from donors with circulatory death. (authorea.com)
  • Hypothermia is called "Prophylactic", if it is administered early after injury (i.e head injury) and prior to increase in intra cranial pressure. (criticalcareindia.com)