This, combined with a relative deficit in GABAergic input to Wernicke's area, shifts the balance of bilateral communication across the corpus callosum posteriorly. (wikipedia.org)
In addition, subgroup analyses were performed to determine long-term training benefit in the presence of lesions in corpus callosum, deep-brain-nuclei and prefrontal cortex. (edu.au)
Social isolation reduced the density of NADPH-diaphorase - containing neurons in the corpus callosum, as well as in the precentral medial cortex (only in females). (ihna.ru)
Dopamine5
Current evidence indicates that symptoms of Parkinson's disease are related to depletion of dopamine in the corpus striatum. (nih.gov)
Dopamine acting in the striatum is necessary for normal movement and motivation. (jneurosci.org)
Using the 6-hydroxydopamine lesion model of Parkinson's disease and differential display PCR, we have identified a set of more than 30 genes whose expression rapidly increases in response to stimulation of striatal dopamine D 1 receptors. (jneurosci.org)
Dopamine acts in the striatum through the D 1 and D 2 subfamilies of G-protein-coupled receptors. (jneurosci.org)
Effects of (R)-ketamine, (S)-ketamine, and their metabolites on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-induced reduction of dopamine transporter (DAT) and tyrosine hydroxylase (TH) in the mouse striatum and substantia nigra (SNr) were examined. (unboundmedicine.com)
Prefrontal cortex1
striatum, prefrontal cortex, nucleus accumbens, amygdala, hippocampus (all structures indicated in this disease), and currently thought to be a reason why antipsychotics with 5HT2C antagonistic properties improves negative symptoms. (wikipedia.org)
Ischemic stroke1
In the setting of acute ischemic stroke with hemorrhagic transformation, MR with diffusion-weighted (DW) imaging is often key to making a diagnosis that could be missed on a noncontrast CT alone, and even on a CT that includes CTA and CTP, depending on the site and size of the infarct that underlies the hemorrhage. (radiologykey.com)
Neurodegenerative3
This enables us to follow histopathological changes in course of neurodegenerative process (NDP) within the striatum and compare them with postmortem samples of human HD brains. (hindawi.com)
Parkinson's disease (PD) is characterized as a chronic and progressive neurodegenerative disorder, and PD patients have non-motor features such as depressive symptoms. (unboundmedicine.com)
It is becoming increasingly clear that, particularly for chronic neurodegenerative disorders occurring late in life, a complex combination of risk factors can initiate disease development and modify proteins that have a physiological function into ones with pathological roles via a number of defined mechanisms (Moreno-Gonzalez and Soto, 2011). (maxwellmagneticmeds.co.za)
Neurological3
Although pneumonia and acute respiratory failure are the most frequent and severe complications of patients with SARS-CoV-2 infection, many of them also develop neurological signs and symptoms. (scientificarchives.com)
They can be classified from acute neurological manifestations as anosmia, ageusia or sickness behavior, to long-term consequences such as cognitive decline or mood disorders. (scientificarchives.com)
Purpose : Perinatal asphyxia occurring in newborn is one of the major causes of acute mortality and chronic neurological disability in survivors. (e-cep.org)
Cerebellum2
Differences between baseline and postacupuncture (PA) perfusion levels showed were highest in the hippocampus region, followed by the striatum, thalamus, and cerebellum regions. (jmedscindmc.com)
The activity of NO synthase increased in acute separation (in the cerebellum) and chronic separation (in all studied structures). (ihna.ru)
Traumatic1
2016. Dr N-N.RABELO, H.MATUSHITA, D-D.CORDEAL : Traumatic brain lesion in newborns. (atide-asso.org)
Obstructive Pulmonary Disease1
The objective of this study was to examine the impact of neuroticism as a moderator of physical symptoms and development of depression in patients with amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), end-stage renal disease (ESRD), and frailty in the last 6 months of life. (cambridge.org)
Gene expression3
One example is dynorphin gene expression, which is progressively induced in dorsal striatum by cocaine. (jneurosci.org)
Differential gene expression in the striatum of mice with very low expression of the vesicular monoamine transporter type 2 gene. (neurotree.org)
Here, we find that persistent mtDNA stress is not associated with basally activated NF-κB signalling or interferon gene expression typical of an acute antiviral response. (regenerativemedicine.net)
Antiviral1
In conclusion, our findings underscore the potential of QL-007 as an effective agent against HBV replication and introduce it as a novel CpAM for the antiviral treatment of chronic hepatitis B. (bvsalud.org)
Rats2
The unimpaired forelimb in lesioned rats was immobilized with a one-sleeved cast during the period of dendritic enhancement (days 1-15 postlesion). (jneurosci.org)
Our previous mRNA-seq data revealed a 1.8-2.5 fold increase in clusterin mRNA expression in lesioned brain areas in rats with lateral fluid-percussion injury (FPI)-induced TBI. (nature.com)
Neuroinflammation1
We also quantified sub-acute neuroinflammation in the post-stroke brain in a separate cohort of mice following a 60 min transient middle cerebral artery occlusion (tMCAo). (frontiersin.org)
Disorders2
Acute and chronic disorders such as MS, neuromyelitis optica spectrum disorder, transverse myelitis, and optic neuritis result in progressive demyelination of nerve axons in the brain, spinal cord, or optic nerve. (scientificarchives.com)
Cognitive-motor dissociation has been shown to occur in approximately 15% to 20% of clinically unresponsive patients with both acute and chronic disorders of consciousness. (medlink.com)
Injury1
Thus, dendritic growth may be associated with an interaction between brain injury and learning-dependent use of the intact forelimb in compensating for lesion-induced deficits in the impaired forelimb. (jneurosci.org)
Auditory1
This retrograde signaling to the temporal lobes that results in the parietal lobes not recognizing it as internal results in the auditory hallucinations typical of chronic schizophrenia. (wikipedia.org)
Reactive1
Regardless of the development of reactive gliosis within the striatum, loss of the grey matter is extensive and results in the compensatory enlargement of lateral brain ventricles. (hindawi.com)
Abnormal3
Abnormal expression, thus distribution of the D2 receptor between these areas and the rest of the brain may also be implicated in schizophrenia, specifically in the acute phase. (wikipedia.org)
This is a direct result of the abnormal dopaminergic input to the striatum, thus (indirectly) disinhibition of thalamic activity. (wikipedia.org)
MPTP-induced reduction of DAT in the striatum was attenuated by subsequent repeated intranasal administration of both enantiomers of ketamine although (R)-ketamine was more potent than (S)-ketamine. (unboundmedicine.com)
MPTP-induced reduction of TH in the striatum and SNr was attenuated by administration of (R)-ketamine, but not (S)-ketamine. (unboundmedicine.com)
Interestingly, MPTP-induced reduction of DAT in the striatum was also attenuated by a single intranasal administration of (R)-ketamine. (unboundmedicine.com)
In contrast, MPTP-induced reduction of DAT in the striatum was not attenuated by repeated intranasal administration of two enantiomers of norketamine. (unboundmedicine.com)
Furthermore, the pretreatment with TrkB antagonist ANA-12 significantly blocked the neuroprotective effects of (R)-ketamine in the MPTP-induced reduction of DAT in the striatum. (unboundmedicine.com)
Brain5
As a result of dependence upon higher brain centers, certain lesions or diseases of the brain (eg, stroke, cancer, dementia) can result in a loss of voluntary control of the normal micturition reflex as well as symptoms such as urinary urgency. (medscape.com)
Certain lesions or diseases of the brain, including stroke, cancer, or dementia, result in loss of voluntary control of the normal micturition reflex. (medscape.com)
MR with gradient-recalled echo (GRE) imaging is sensitive to acute hemorrhage, but MR (often with MR angiography [MRA], MR venography [MRV], and/or MR perfusion) is usually performed following CT to assess the cause of a known hemorrhage and to evaluate its effect on the rest of the brain parenchyma. (radiologykey.com)
On CT, acute blood is dense compared with brain tissue and CSF, and gradually decreases in density over days to weeks depending on the size of the hematoma. (radiologykey.com)
2015. Dr V.VLASYUK : Nosology lesions of the white matter of the brain in newborns and young children. (atide-asso.org)
Severe2
Immobilization of the nonimpaired forelimb resulted in chronic prevention of dendritic growth and severe and chronic behavioral deficits. (jneurosci.org)
Acute: Having rapid onset, severe symptoms, and a short course. (chiariproject.org)
Demyelination1
Chronic hexane exposure causes segmental demyelination in the peripheral nerves, and high-dose intoxication may also affect central nervous system. (biomedcentral.com)
Symptoms1
While these substances act on different neurotransmitter receptors, they all produce strong subjective effects that can be compared to the symptoms of acute psychosis, including ego dissolution. (frontiersin.org)
Mild1
Immobilization of the impaired forelimb resulted in no detectable neural changes and in only slightly increased and longer-lasting behavioral asymmetries (compared to nonimmobilized, lesioned animals), presumably attributable to mild disuse of the impaired limb. (jneurosci.org)
Asthma1
As an example, acute inhalation MRLs may not be protective for health effects that are delayed in development or are acquired following repeated acute insults, such as hypersensitivity reactions, asthma, or chronic bronchitis. (cdc.gov)
Activity2
Classification of activity tolerance is of importance in chronic progressive myopathies, not only to better understand functional implications of the disease state itself, but also for purposes of exercise prescription for health maintenance. (stanford.edu)
Chronic isolation did not significantly affect the activity of the enzyme. (ihna.ru)
Period3
When one-sleeved casts were used to prevent animals with an FL-SMC lesion from using their unimpaired forelimb during the period of expected overgrowth, lesion-induced dendritic enhancement was not present when examined 2 d after cast removal. (jneurosci.org)
The initial aim of the study was to address whether there was an optimal period for lesion-induced changes in the contralateral homotopic cortex and for behavioral recovery. (jneurosci.org)
CONCLUSIONS: This study provides preliminary evidence that cognitive training, beyond the acute rehabilitation period in adolescents with TBI is effective to boost executive functioning in daily living. (edu.au)
Addition1
in addition, MR is sensitive to both acute and chronic hemorrhage, whereas CT is most sensitive to acute blood products. (radiologykey.com)
Animals1
Animals with FL-SMC lesions were fitted with casts immediately after the lesion that immobilized the impaired forelimb, the unimpaired forelimb, or neither forelimb for 15 d. (jneurosci.org)
Days2
1-4 The subacute nature of RPD excludes other conditions with fulminant progression such as infectious or metabolic acute encephalopathies, which progress within hours or days and typically commence as an acute confusional state. (touchneurology.com)
15-364 days), and chronic (365 days or more). (cdc.gov)
Late2
Vertically paired images of acute, early subacute, and late subacute hematomas. (radiologykey.com)
This finding is consistent with intracellular methemoglobin in the hematoma (H). ( E ) Sagittal T1W image in a patient with a large right frontotemporal late subacute hematoma shows bright signal in the lesion. (radiologykey.com)