• Although 75-85% of patients presenting to the emergency department with chest pain ultimately do not receive a diagnosis of acute coronary syndrome, a lengthy assessment process is still mandatory as patients with a missed diagnosis of myocardial infarction are at increased risk for a cardiovascular event. (bmj.com)
  • Acute Coronary Syndrome (ACS) is a spectrum of thrombotic coronary artery diseases, including unstable angina, ST-elevation myocardial infarction and non-ST elevation myocardial infarction resulting from sudden cardiac ischemia. (springer.com)
  • To study socioeconomic inequalities in the incidence of acute myocardial infarction (AMI), the major component of CHD, a meta-analysis was undertaken to summarise existing evidence on the issue. (bmj.com)
  • Acute appendicitis is the most frequent cause of nontraumatic acute abdominal pain that requires emergency surgery. (springer.com)
  • After an anatomical and pathophysiological review, we will highlight the use and impact of CT in the diagnosis and management of acute appendicitis. (springer.com)
  • Alvarado A (1986) A practical score for the early diagnosis of acute appendicitis. (springer.com)
  • Balthazar EJ, Birnbaum BA, Yee J, Megibow AJ, Roshkow J, Gray C (1994) Acute appendicitis: CT and US correlation in 100 patients. (springer.com)
  • This article reviews the presentation, investigation, treatment, and complications of acute appendicitis and appendicectomy. (bmj.com)
  • 3 Since the 1940s the incidence of hospital admission for acute appendicitis has been falling, but the reason for this decline is not clear. (bmj.com)
  • Diagnosis of acute appendicitis relies on a thorough history and examination. (bmj.com)
  • Abdominal pain is the primary presenting complaint of patients with acute appendicitis. (bmj.com)
  • Alvarado (MANTRELS) score [45] Alvarado A. A practical score for the early diagnosis of acute appendicitis. (bmj.com)
  • The higher the score out of a possible total of 10, the greater the chance of having acute appendicitis. (bmj.com)
  • Histological audit of acute appendicitis. (bmj.com)
  • Objective: To identify risk factors for acute renal failure (ARF) in HIV-infected patients. (natap.org)
  • Acute bronchitis is a short term lung infection. (epnet.com)
  • All patients suspected of having an acute prostatic infection underwent computed tomography or transrectal ultrasonography to discriminate acute prostatic abscesses from acute prostatitis without abscess formation. (urotoday.com)
  • Recurrence of acute bronchitis is common in subsequent viral infection seasons, especially in smokers. (bmj.com)
  • Acute anterior uveitis after yersinia infection. (bmj.com)
  • Twenty-eight cases of acute anterior uveitis in which raised antibody titres indicated yersinia infection as a possible causative factor in the disease were studied retrospectively. (bmj.com)
  • In conclusion, occult HBV infection persists in the liver and is accompanied by abnormal liver histology for a decade after complete clinical recovery from acute self-limited hepatitis B. (natap.org)
  • In contrast, a vigorous, polyclonal, and HBV-specific CTL response against multiple HBV epitopes is readily detectable during acute self-limited HBV infection. (natap.org)
  • HBV-specific CTLs further persist in the blood for several decades after recovery from acute hepatitis B. In the face of an enhanced immune response leading to disease resolution, the virologic outcomes of acute self-limited hepatitis B may differ from those of HBsAg seroclearance and anti-HBs seroconversion in the course of chronic HBV infection. (natap.org)
  • All three patients suffered an episode of massive acute haemolysis, in the absence of blood group incompatibilities, infection, or ingestion of oxidising agents known to trigger haemolysis. (bmj.com)
  • We describe three neonates with G6PD deficiency who developed severe hyperbilirubinaemia requiring exchange transfusion because of massive acute haemolysis, in the absence of any obvious blood group incompatibilities, infection, or ingestion of oxidising agents known to trigger haemolysis by either the mother or infant. (bmj.com)
  • Acute otitis media (AOM) is a common type of ear infection that mostly occurs in children where the middle ear becomes infected and subsequently inflamed. (epainassist.com)
  • Intravenous glucose-insulin-potassium (GIK) is postulated to be beneficial in acute ischaemic syndromes via two mechanisms: by providing metabolic support to ischaemic myocardium, and by preventing arrhythmias and cardiac arrest due to ischaemia-related metabolic derangements. (bmj.com)
  • But this cell-therapy approach had not been tried before in adults with the disease that Emma had, acute lymphoblastic leukemia. (nytimes.com)
  • Dr. Carl June of the University of Pennsylvania, who led the team that treated Emma and the other patients, said, "This is the first report showing some real, clinically beneficial activity in adult acute lymphoblastic leukemia. (nytimes.com)
  • An antibody packaged with a potent chemotherapy drug to selectively destroy acute lymphoblastic leukemia (ALL) cells eradicated or greatly reduced the disease for 61 percent of 46 patients in a phase II study. (healthcanal.com)
  • The purpose of this study was to review the data on the etiology, risk factors, clinical presentations, and diagnosis of acute sacroiliitis. (springer.com)
  • Following these discussions, AMEH and ASH invited the U.S. National Cancer Institute (NCI) Office of Latin American Cancer Program Development to form a partnership dedicated to improving clinical management and research for the treatment of acute myeloid leukemia (AML) in Mexico. (healthcanal.com)
  • I investigated injury situations and methods for clinical and imaging examinations in the diagnosis of acute groin injuries in athletes. (bmj.com)
  • The clinical features and course of the disease did not differ from those of acute anterior uveitis due to other causes. (bmj.com)
  • Comprehensive systematic review and meta-analysis of prognostic models in acute pulmonary embolism (PE) that was not restricted to only clinical prediction rules and derivation or validation studies, but was expanded to all available prediction/predictive models including update and impact studies to inform clinical decisions, with broad search strategy and predefined selection criteria, and no data or language restriction. (bmj.com)
  • Overall, all patients showed complete clinical and serologic recovery from acute hepatitis B... Histopathologic examination showed that a low grade of liver inflammation had persisted for a decade. (natap.org)
  • Fourteen patients were recalled at a median of 4.2 years (range, 1.8-9.5 years) after the onset of acute hepatitis B. All showed clinical and serologic recovery with circulating hepatitis B surface antigen (HBsAg) clearance. (natap.org)
  • Background: The clearance of circulating hepatitis B surface antigen (HBsAg) and appearance of antibody to HBsAg (anti-HBs) with normalization of liver function have been generally accepted as evidence of clinical and serologic recovery from acute hepatitis B. However, in chronic HBsAg carriers, there is growing evidence that hepatitis B virus (HBV) DNA sequences persist in the liver for years after seroclearance of HBsAg and seroconversion to anti-HBs. (natap.org)
  • Recognize typical and atypical symptoms of acute coronary syndrome (ACS). (aafp.org)
  • Acute radiation syndrome (ARS) , also called radiation sickness , is the result caused by receiving a dose greater than 75 rads (0.75 Gray (Gy)) of ionizing radiation [1] to the body in a short time (usually minutes). (citizendium.org)
  • How well do physicians assess risk in non-ST elevation (NSTEMI) acute coronary syndrome (ACS) patients? (bmj.com)
  • Brooklyn, NY -- ( SBWIRE ) -- 03/06/2018 -- Qyresearchreports include new market research report "Global Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) Market Size, Status and Forecast 2025" to its huge collection of research reports. (sbwire.com)
  • A newly added research report about the global market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) produces a 360-degree overview of it. (sbwire.com)
  • The various segments of the global market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) have been discussed carefully at length. (sbwire.com)
  • This enables it to find out the global market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome)'s growth prospects. (sbwire.com)
  • This helps to furnish a granular overview of the market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) and the areas where main opportunities lie. (sbwire.com)
  • This report studies the global Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) market, analyzes and researches the Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) development status and forecast in United States, EU, Japan, China, India and Southeast Asia. (sbwire.com)
  • A thorough examination of the competitive landscape of the global market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) has also been provided in the report. (sbwire.com)
  • Prominent participants in the global market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) have been examined and data pertaining to their sales and revenues, among other things, have been presented. (sbwire.com)
  • The primary intention of the report is to help the companies operating in the global market for Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) to gain an insight into the current market dynamics, including opportunities and pitfalls that would enable them to strategize sagaciously. (sbwire.com)
  • Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are medical conditions that occur when there is severe inflammation and increased fluids in both lungs, making it difficult for the lungs to function properly. (clinicaltrials.gov)
  • In the MATRIX trial, 7213 patients with an acute coronary syndrome (55% with ST-elevation) were randomly allocated to receive either bivalirudin or heparin at 70-100u/kg peri-procedurally with an additional randomization step at procedural completion to either stop bivalirudin or continue the infusion for 4 to 6 hours. (bmj.com)
  • Does telephone triage of emergency calls identify patients with acute coronary syndrome? (bmj.com)
  • The National Service Framework for Coronary Heart Disease requires identification of patients with an acute coronary syndrome (ACS) to enable them to receive pre-hospital thrombolysis. (bmj.com)
  • No prospective studies including large numbers of dogs with acute haemorrhagic diarrhoea syndrome (AHDS) are published so far. (bmj.com)
  • Upper respiratory tract infections often precede acute bronchitis, with overlapping symptoms including headache, nasal congestion, sore throat. (wikipedia.org)
  • Depending on the type and amount of irritant gas inhaled, victims can experience symptoms ranging from minor respiratory discomfort to acute airway and lung injury and even death. (wikipedia.org)
  • Nearly all patients with acute bronchitis recover within 6 weeks of their initial symptoms. (bmj.com)
  • Patients generally return to full function with no residual symptoms following acute bronchitis. (bmj.com)
  • In patients with acute rhinosinusitis and a history of chronic or recurrent sinus symptoms, is the addition of intranasal fluticasone to cefuroxime more effective than the addition of placebo for prompting recovery? (bmj.com)
  • In the USA, an estimated 3 million patients per year are treated for symptoms suggestive of acute rhinosinusitis. (bmj.com)
  • RESULTS: The symptoms and signs of acute vestibular neuritis are vertigo, vomiting, nystagmus with ipsiversive slow-phases, ipsiversive lateropulsion and ocular tilt reaction (the static symptoms) and impairment of vestibulo-ocular reflexes from the ipsilesional semicircular canals on impulsive testing (the dynamic symptoms). (uzh.ch)
  • Acute may refer to: Acute angle Acute triangle Acute, a leaf shape in the glossary of leaf morphology Acute (medicine), a disease that it is of short duration and of recent onset. (wikipedia.org)
  • There are a number of classifications of ALF in use but in the UK the terms hyperacute, acute, and subacute are used to define the onset of encephalopathy within 7 days, 8-28 days, and more than 28 days, respectively. (bmj.com)
  • the fibrosis stage was related to the viral loads in the acute phase and seemed to be determined by the nature of the disease at the onset. (natap.org)
  • Abstract: The long-term impact of acute self-limited hepatitis B on the liver is unknown. (natap.org)
  • There are 332 doctors for Acute Sinusitis in Bessemer . (healthgrades.com)
  • The patients in the study by Dolor et al were not previously healthy people with an isolated episode of acute sinusitis. (bmj.com)
  • This study does not prove that fluticasone speeds resolution of acute bacterial sinusitis unrelated to atopy. (bmj.com)
  • A lack of investment in new antibiotics for acute illness due to a preference to invest in new, more profitable, medication for chronic conditions means an increasing number of people die needlessly from infections exacerbated by bacterial resistance. (thefreedictionary.com)
  • Somatically acquired mutations in DNMT3A occur in haematological malignancies and are frequently present in acute myeloid leukaemia (AML) affecting in more than 50% the arginine residue at position 882 (R882). (bmj.com)
  • Acute viral and bacterial infections of the salivary glands. (medscape.com)
  • The purpose of this study was to identify risk factors for abscess formation in acute bacterial prostatitis, and to compare treatment outcomes between abscess group and non-abscess group. (urotoday.com)
  • Food poisoning is an acute illness that occurs when bacteria, viruses or other germs are absorbed by food substances consumed by people," Dr Alessai explained, adding that bacterial growth in food is likely to occur when food is not kept cold enough. (thefreedictionary.com)
  • QUESTION: In patients with acute bacterial meningitis, does adjunctive treatment with dexamethasone improve outcomes more than placebo? (bmj.com)
  • In patients with acute bacterial meningitis, adjunctive treatment with dexamethasone was more effective than placebo in improving disability and reducing death. (bmj.com)
  • ACR Appropriateness Criteria® Acute Pyelonephritis. (urotoday.com)
  • Acute tubular necrosis (ATN) is a kidney disorder involving damage to the tubule cells of the kidneys, which can lead to acute kidney failure . (baptistjax.com)
  • Objectives To identify all patients tested positive for herpes viruses in intraocular samples between 2007 and 2016 in South-Western Sweden and evaluate which of these met the criteria of acute retinal necrosis (ARN). (bmj.com)
  • To determine whether polymorphisms of the genes encoding donor or recipient interleukin 1α (IL-1α), tumour necrosis factor α (TNFα), or IL-4 have any impact on the incidence of acute rejection after renal transplantation. (bmj.com)
  • Pathogenesis of acute and chronic complications. (bmj.com)
  • Acute cystitis is inflammation of the bladder. (epnet.com)
  • High levels of welding fume exposure induce acute systemic inflammation in a relatively young, healthy working population. (bmj.com)
  • Severe exposure may result in changes in upper and lower airways resulting in an acute lung injury, which may not be present until several hours after exposure. (wikipedia.org)
  • Acute Lung Injury - Pipeline Review, H1 2014, provides an overview of the Acute Lung Injurys therapeutic pipeline. (sbwire.com)
  • This report provides comprehensive information on the therapeutic development for Acute Lung Injury, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. (sbwire.com)
  • It also reviews key players involved in the therapeutic development for Acute Lung Injury and special features on late-stage and discontinued projects. (sbwire.com)
  • Asthma, acute lung damage (ALI), and chronic obstructive pulmonary disease (COPD) are lung inflammatory disorders having a common end result, that is, problems in deep breathing. (exposed-skin-care.net)
  • COVID-19 was diagnosed from disease caused by severe acute respiratory syn- results of real-time reverse transcription PCR, mi- drome coronavirus 2 (SARS-CoV-2). (cdc.gov)
  • The grant will be used to reduce the prevalence of child morbidity and mortality that may occur as a result of acute illness and severe injury. (thefreedictionary.com)
  • The recently revised British Guideline on the Management of Asthma suggests also using a single dose of i.v. magnesium sulphate in patients with acute severe asthma, an unlicensed indication. (bmj.com)
  • 2 Here we discuss the rationale for giving i.v. magnesium and whether it offers any advantage for patients with acute severe asthma. (bmj.com)
  • A severe common cold may cause one to excessively blow resulting in blockages and ultimately, acute otitis media. (epainassist.com)
  • Where the mixture has been tested to determine its acute toxicity, it is classified according to the criteria provided in Table A.1.1. (osha.gov)
  • Eligibility criteria Studies aiming at constructing, validating, updating or studying the impact of prognostic models to predict all-cause death, PE-related death or venous thromboembolic events up to a 3-month follow-up in patients with an acute symptomatic PE. (bmj.com)
  • Where there is evidence of acute toxicity by multiple routes of exposure, classification is to be conducted for all appropriate routes of exposure. (osha.gov)
  • The incidence of acute and chronic leukemias is about the same. (thefreedictionary.com)
  • After stratification for human leucocyte antigen (HLA) matching, it was found that kidneys from donors positive for the TNFA-A allele had a significantly increased incidence of acute rejection in HLA-DR mismatched transplants. (bmj.com)
  • However, at present there are no laboratory assays that are capable of predicting the incidence of acute rejection. (bmj.com)
  • The two most common treatments for acute otitis media are medications and surgery. (epainassist.com)
  • If treatment is delayed, the patient is immunocompromised, or for other reasons, microabscesses that form during the acute phase of pyelonephritis may coalesce, forming a renal abscess. (urotoday.com)
  • Univariate analysis revealed that symptom duration, diabetes mellitus and voiding disturbance were predisposing factors for abscess formation in acute prostatitis. (urotoday.com)
  • In contrast, Escherichia coli was the predominant organism responsible for acute prostatitis without abscess. (urotoday.com)
  • This module offers a practical, step by step guide for GPs on diagnosing and managing acute asthma/wheezing attacks in children. (bmj.com)
  • Intravenous magnesium for acute asthma? (bmj.com)
  • The best way to treat acute otitis media is by use of natural home remedies. (epainassist.com)
  • Acquired coagulopathy is a relatively uncommon occurrence in acute paediatrics but when it occurs is usually associated with significant underlying pathology and often with critical illness. (bmj.com)
  • It remains uncertain whether the sweeping changes in the treatment of acute coronary syndromes have had a substantial impact on the incidence of cardiogenic shock. (bmj.com)
  • Acute sacroiliitis can rarely be also related to hematological malignancies or treatment with isotretinoin. (springer.com)
  • Awareness to the possibility of acute sacroiliitis and a thorough physical examination are the necessary prerequisites to its timely diagnosis, while the appropriate laboratory and imaging studies should confirm the precise diagnosis and direct the appropriate treatment strategy. (springer.com)
  • SSRI treatment commenced in the acute phase of stroke (day 2-5) protects against new thromboembolic events and leads to better rehabilitation. (clinicaltrials.gov)
  • A treatment that genetically alters a patient's own immune cells to fight cancer has, for the first time, produced remissions in adults with an acute leukemia that is usually lethal, researchers are reporting. (nytimes.com)
  • Imaging studies should be considered when patients with acute prostatitis have delayed treatment and signs of voiding disturbance. (urotoday.com)
  • Colgan R, Williams M. Diagnosis and treatment of acute uncomplicated cystitis. (epnet.com)
  • Role of streptokinase in the treatment of acute loculated parapneumonic pleural effusions and empyema. (bmj.com)
  • BACKGROUND: Cytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). (uzh.ch)
  • CONCLUSIONS: The persistent loss of balance that some patients experience after acute vestibular neuritis can be due to inadequate central compensation or to incomplete peripheral recovery and vestibular rehabilitation has a role in the treatment of both. (uzh.ch)
  • Pharmacologic therapy may be useful as emergency treatment for acute pericardial tamponade while preparing for pericardiocentesis. (elsevier.com)
  • The good thing also is that most of the times, acute otitis media will heal without even the use of anti-biotic treatment. (epainassist.com)
  • Acute leukemias are the rapidly progressing leukemias, while the chronic leukemias progress more slowly. (thefreedictionary.com)
  • Acute Physiology and Chronic Health Evaluation II (APACHE II) score [46] Knaus WA, Draper EA, Wagner DP, et al. (bmj.com)
  • It is clear that although HLA matching improves graft outcome, acute and chronic rejection of the allograft is still a problem with both cadaveric and living donors. (bmj.com)
  • Acute liver failure is a complex multisystemic illness that evolves quickly after a catastrophic insult to the liver leading to the development of encephalopathy. (bmj.com)
  • Acute liver failure (ALF) is a complex multisystemic illness that evolves after a catastrophic insult to the liver manifesting in the development of a coagulopathy and encephalopathy within a short period of time. (bmj.com)
  • When they arrive it may be that they have an acute illness or that they need a fit note. (thefreedictionary.com)
  • Patients with acute illness such as heart attacks, strokes, and other health catastrophes have much improved outcomes when care is provided in large district hospitals with established rotas of trained doctors and nurses who see enough patients to maintain skills and train junior staff. (thefreedictionary.com)
  • In the case of an acute illness , avoid all types of exercise. (thefreedictionary.com)
  • However, during acute illness patients become extremely insulin resistant. (thefreedictionary.com)
  • The contributions that make up the bulk of the text cover epidemiology of hyperglycemia in the hospital setting, pathophysiological mechanisms of hyperglycemia mediated damage in acute illness , glucose monitoring of hospital patients, choosing the glycemic target for management of inpatient hyperglycemia, and a variety of other related subjects. (thefreedictionary.com)
  • He said that while his research team did not study other kinds of inflammatory disorders, "the same benefits of psychological stress should accrue in any acute illness or injury. (thefreedictionary.com)
  • The acute illness is accompanied by a high fever, weakness, swelling of the lower legs and abdomen, irregular heartbeat and a weak pulse. (thefreedictionary.com)
  • For patients recently discharged on supplemental home oxygen following hospitalization for an acute illness , do not renew the prescription without assessing the patient for ongoing hypoxemia. (thefreedictionary.com)
  • Acute cerebellar ataxia in children, particularly younger than age 3, may occur several weeks after an illness caused by a virus. (baptistjax.com)
  • Acute kidney damage (AKI) can be a frequent problem of pediatric cardiac medical procedures and negatively results brief- and long-term results.1-5 Despite decades of research no therapy has proved very effective for the procedure or prevention of human AKI. (exposed-skin-care.net)
  • ATN is one of the most common structural changes that can lead to acute kidney failure. (baptistjax.com)
  • Acute kidney injury. (baptistjax.com)
  • The new study, in five adults with acute leukemia in whom chemotherapy had failed, was published Wednesday in the journal Science Translational Medicine . (nytimes.com)
  • Acute leukemias are of two types: acute lymphocytic leukemia and acute myelogenous leukemia. (thefreedictionary.com)
  • In acute lymphocytic leukemia (ALL), it is the T or the B lymphocytes that become cancerous. (thefreedictionary.com)
  • Acute myelogenous leukemia, also known as acute nonlymphocytic leukemia (ANLL), is a cancer of the monocytes and/or granulocytes. (thefreedictionary.com)
  • Acute inhalation injury may result from frequent and widespread use of household cleaning agents and industrial gases (including chlorine and ammonia). (wikipedia.org)
  • Currently, mechanical ventilation remains the therapeutic mainstay for pulmonary dysfunction following acute inhalation injury. (wikipedia.org)
  • Anatomical studies have provided greater insight into the complexity of the musculotendinous structures in the groin, but the relationship with acute injury was unexplored. (bmj.com)
  • Elite and subelite athletes with acute groin pain presenting at Aspetar Sports Medicine Hospital (Doha, Qatar) within 1 week of injury were included. (bmj.com)
  • Acute cerebellar ataxia is sudden, uncoordinated muscle movement due to disease or injury to the cerebellum. (baptistjax.com)
  • The aim of our study was to identify non-HLA risk factors for acute rejection, which could be used in pretransplant patient assessment. (bmj.com)
  • Artificial liver support devices remain unproven in efficacy in acute liver failure. (bmj.com)
  • The fibrosis stage had relation to peak serum HBV DNA in the acute phase (P = .046) but not to liver viral loads in the late convalescent phase. (natap.org)
  • At present, the long-term histologic and virologic impact of acute self-limited hepatitis B on the liver is unexplored. (natap.org)
  • Sonmez FM, Odemis E, Ahmetoglu A, Ayvaz A. Brainstem encephalitis and acute disseminated encephalomyelitis following mumps. (medscape.com)
  • Acute toxicity, the adverse effects of a substance from a single exposure or in a short period of time Acute accent, a diacritic used in many modern written languages Acute (phonetic), a perceptual classification This disambiguation page lists articles associated with the title Acute. (wikipedia.org)
  • Is the "unknown acute toxicity" statement only required when there is no acute toxicity information on all routes of exposure (oral, dermal, and inhalation)? (osha.gov)
  • For example, if the acute toxicity values are available for the acute oral and dermal exposure for an ingredient and the acute inhalation toxicity data is missing, should a statement of "X% of mixture consists of ingredient(s) of unknown acute inhalation toxicity" be included in section 2 of the SDS? (osha.gov)
  • The unknown acute toxicity statement is only required on the label and the SDS where the chemical mixture is already classified as acutely toxic for a particular route of exposure, and there are one or more other "relevant ingredients" (as defined under 29 CFR 1910.1200, Appendix A, A.1.3.3) of unknown acute toxicity for that particular route. (osha.gov)
  • HCS 2012 specifies that classification of mixtures for acute toxicity may be carried out for each route of exposure, but is only required for one route of exposure as long as this route is followed (estimated or tested) for all ingredients and there is no relevant evidence to suggest acute toxicity by multiple routes. (osha.gov)
  • To examine the acute effects of Advance TM , a potential reduced exposure product (PREP) for smokers marketed as a means to reduce exposure to toxic gases and tobacco specific nitrosamines. (bmj.com)
  • Objective post-marketing evaluation, in the form of acute exposure studies, reveals important characteristics of some PREPs, such as Eclipse ® 's greater-than-usual-brand CO delivery. (bmj.com)
  • While several days' exposure is required for any measurable difference in TSN delivery to be observed (TSN metabolites have a distribution half life of 3-4 days 8 ), acute studies can help to determine other PREP effects. (bmj.com)
  • To investigate the acute systemic inflammatory response to welding fume exposure. (bmj.com)
  • Objective To ascertain whether there was an association between parental occupational exposure to pesticides and increased risk of acute lymphoblastic leukaemia (ALL) in the offspring. (bmj.com)
  • Conclusions Paternal occupational exposure to pesticides was not found to be associated with an increased risk of acute lymphoblastic leukaemia in the offspring. (bmj.com)
  • 5 Here we review the evidence on the efficacy of antibacterials in acute infective conjunctivitis. (bmj.com)
  • There are several other models that have been developed for use in the ICU, including APACHE III, Mortality in Emergency Department Sepsis score, Simplified Acute Physiology Score, Sepsis-related Organ Failure Assessment, and Mortality Probability Model II. (bmj.com)
  • An antiserum to the insulin receptor mimicked insulin's acute actions on glucose transport, phosphorylation of integral membrane proteins, and internalization of the insulin receptor in isolated rat adipose cells. (elsevier.com)
  • Thus, a role of receptor phosphorylation in acute insulin action is now questioned. (elsevier.com)
  • Simpson, IA & Hedo, JA 1984, ' Insulin receptor phosphorylation may not be a prerequisite for acute insulin action ', Science , vol. 223, no. 4642, pp. 1301-1304. (elsevier.com)
  • 1% and the mixture is not classified based on testing of the mixture as a whole, a statement that X% of the mixture consists of ingredient(s) of unknown acute toxicity is required. (osha.gov)
  • The approach in HCS 2012 for classifying mixtures for acute toxicity is tiered, and is dependent on the amount of information available for the mixture itself and for its ingredients. (osha.gov)
  • If there is no acute toxicity data for the mixture, A.1.3.5 requires that classification be based on bridging principles. (osha.gov)
  • Where there is data for all ingredients, an acute toxicity estimate (ATE) is followed, per A.1.3.6.1. (osha.gov)
  • 1%, and the mixture is not classified based on testing of the mixture as a whole, the mixture cannot be attributed a definitive acute toxicity estimate. (osha.gov)
  • Classifiers can present the unknown acute toxicity information on ingredients either as a single statement or as multiple statements, where routes are differentiated. (osha.gov)
  • Objective To review the evidence for existing prognostic models in acute pulmonary embolism (PE) and determine how valid and useful they are for predicting patient outcomes. (bmj.com)
  • In this latest study of bivalirudin versus heparin, there was no difference in outcomes between the two drugs among patients undergoing PCI for acute coronary syndromes. (bmj.com)
  • Elevated blood glucose at hospital admission, and elevated fasting blood glucose levels during admission, have been shown to predict worse outcome among patients with STEMI, however, the contribution of glucose levels to risk predictive algorithms involving patients with acute coronary syndromes (ACS) remains unclear. (bmj.com)