Acts as a tumor suppressor gene genes tumor suppressor. Medical search. Frequent questions

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Anatomy24

Cell Line, Tumor Tumor Cells, Cultured Chromosomes, Human, Pair 3 Cell Line Chromosomes, Human, Pair 9 Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 10 Cells, Cultured Chromosomes, Human, Pair 17 Chromosomes, Human, Pair 13 Fibroblasts Chromosomes, Human, Pair 1 HCT116 Cells HeLa Cells Cell Nucleus Chromosomes, Human, Pair 8 Cell Line, Transformed Chromosomes, Human, Pair 16 Chromosomes, Human, Pair 6 Epithelial Cells NIH 3T3 Cells T-Lymphocytes, Regulatory HEK293 Cells Chromosomes, Human, Pair 7

Organisms7

Mice, Nude Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Mice, Inbred BALB C Mice, SCID Adenoviridae

Diseases52

Cell Transformation, Neoplastic Neoplasms Wilms Tumor Kidney Neoplasms Chromosome Deletion Breast Neoplasms Adenocarcinoma Neoplasms, Experimental Brain Neoplasms Lung Neoplasms Carcinoma, Squamous Cell Carcinoma, Renal Cell Ovarian Neoplasms Skin Neoplasms Colonic Neoplasms Liver Neoplasms Neoplasm Metastasis von Hippel-Lindau Disease Disease Progression Pancreatic Neoplasms Carcinoid Tumor Glioma Carcinoma, Hepatocellular Mammary Neoplasms, Experimental Neovascularization, Pathologic Glioblastoma Neuroendocrine Tumors Adenoma Neurofibromatosis 2 Osteosarcoma Astrocytoma Mammary Neoplasms, Animal Urinary Bladder Neoplasms Rhabdoid Tumor Chromosome Aberrations Stomach Neoplasms Prostatic Neoplasms Disease Models, Animal Neoplasm Invasiveness Retinoblastoma Lymphoma Colorectal Neoplasms Carcinoma Precancerous Conditions Head and Neck Neoplasms Medulloblastoma Neuroblastoma Fibrosarcoma Neurofibromatosis 1 Meningioma Carcinoma, Non-Small-Cell Lung Esophageal Neoplasms

Chemicals and Drugs75

Tumor Suppressor Proteins Tumor Suppressor Protein p53 Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p16 DNA, Neoplasm Tumor Markers, Biological Retinoblastoma Protein Neoplasm Proteins DNA-Binding Proteins Transcription Factors RNA, Messenger WT1 Proteins Suppressor of Cytokine Signaling Proteins Nuclear Proteins Neurofibromin 2 Proto-Oncogene Proteins c-mdm2 Proto-Oncogene Proteins Tumor Necrosis Factor-alpha Repressor Proteins Proteins Cell Cycle Proteins Ubiquitin-Protein Ligases Phosphoric Monoester Hydrolases Acid Anhydride Hydrolases Cyclin-Dependent Kinase Inhibitor p21 Adenomatous Polyposis Coli Protein DNA Primers Azacitidine Protein-Serine-Threonine Kinases RNA, Small Interfering MicroRNAs Cyclin-Dependent Kinase Inhibitor p15 Carrier Proteins RNA, Neoplasm Trans-Activators Suppressor Factors, Immunologic Membrane Proteins Ligases Neurofibromin 1 BRCA1 Protein Apoptosis Regulatory Proteins Intracellular Signaling Peptides and Proteins Cyclins Carcinogens Recombinant Fusion Proteins beta Catenin Genetic Markers DNA (Cytosine-5-)-Methyltransferase DNA Adaptor Proteins, Signal Transducing Drosophila Proteins DNA, Complementary Proto-Oncogene Proteins c-myc Smad4 Protein Antineoplastic Agents Kruppel-Like Transcription Factors Cadherins Cyclin-Dependent Kinase Inhibitor p27 ras Proteins Core Binding Factor Alpha 3 Subunit DNA Modification Methylases Oncogene Proteins Protein Isoforms Cyclin D1 E2F Transcription Factors Phosphoproteins Recombinant Proteins Cytoskeletal Proteins Antigens, Neoplasm E2F1 Transcription Factor NM23 Nucleoside Diphosphate Kinases Hypoxia-Inducible Factor 1, alpha Subunit Death-Associated Protein Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Transfection Reverse Transcriptase Polymerase Chain Reaction Polymerase Chain Reaction Tumor Burden Chromosome Mapping Immunohistochemistry Neoplasms, Experimental Blotting, Western DNA Mutational Analysis Gene Expression Profiling Transplantation, Heterologous Oligonucleotide Array Sequence Analysis Neoplasm Transplantation Mammary Neoplasms, Experimental Models, Biological Xenograft Model Antitumor Assays Neoplasm Staging Gene Knockdown Techniques Flow Cytometry In Situ Hybridization, Fluorescence Tumor Stem Cell Assay Immunoenzyme Techniques Disease Models, Animal Cloning, Molecular Immunoblotting Prognosis Blotting, Northern Immunoprecipitation Sequence Analysis, DNA Genetic Therapy Blotting, Southern

Phenomena and Processes79

Genes, Tumor Suppressor Genes, p53 Loss of Heterozygosity Gene Expression Regulation, Neoplastic Genes, Suppressor DNA Methylation Mutation Gene Silencing Promoter Regions, Genetic Gene Deletion Base Sequence Cell Proliferation Apoptosis Signal Transduction Suppression, Genetic Genes, Retinoblastoma Transfection Down-Regulation Cell Cycle Chromosomes, Human, Pair 3 Cell Division Genes, Wilms Tumor CpG Islands Genes, p16 Chromosome Deletion Polymorphism, Single-Stranded Conformational Oncogenes Microsatellite Repeats Amino Acid Sequence Alleles Transcription, Genetic Protein Binding Chromosomes, Human, Pair 9 Epigenesis, Genetic Phenotype Genes, ras Exons Gene Expression Genes, DCC Chromosomes, Human, Pair 11 DNA Damage RNA Interference Chromosomes, Human, Pair 10 Chromosomes, Human, Pair 17 Phosphorylation Heterozygote Gene Expression Regulation Chromosomes, Human, Pair 13 Transcriptional Activation Genes, APC Genes, Neurofibromatosis 1 Cell Movement Up-Regulation Chromosomes, Human, Pair 1 Germ-Line Mutation Cell Growth Processes Point Mutation Cell Survival Cell Aging Protein Structure, Tertiary Time Factors Homozygote Genes, Neurofibromatosis 2 Tumor Microenvironment Genetic Markers Chromosomes, Human, Pair 8 Cell Differentiation Chromosome Aberrations Gene Dosage Binding Sites Chromosomes, Human, Pair 16 Sequence Deletion Genes, myc Chromosomes, Human, Pair 6 Genetic Vectors Sequence Homology, Amino Acid G1 Phase Chromosomes, Human, Pair 7 Alternative Splicing

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Genes, Tumor Suppressor Tumor Suppressor Proteins Tumor Suppressor Protein p53 Cell Line, Tumor Genes, p53 Loss of Heterozygosity Gene Expression Regulation, Neoplastic Genes, Suppressor DNA Methylation Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Mutation PTEN Phosphohydrolase Gene Silencing Cyclin-Dependent Kinase Inhibitor p16 Molecular Sequence Data Cell Transformation, Neoplastic DNA, Neoplasm Promoter Regions, Genetic Gene Deletion Base Sequence Tumor Markers, Biological Cell Proliferation Neoplasms Retinoblastoma Protein Wilms Tumor Apoptosis Tumor Cells, Cultured Signal Transduction Neoplasm Proteins DNA-Binding Proteins Suppression, Genetic Transcription Factors RNA, Messenger WT1 Proteins Suppressor of Cytokine Signaling Proteins Kidney Neoplasms Genes, Retinoblastoma Transfection Down-Regulation Cell Cycle Reverse Transcriptase Polymerase Chain Reaction Polymerase Chain Reaction Chromosomes, Human, Pair 3 Cell Division Nuclear Proteins Tumor Burden Chromosome Mapping Genes, Wilms Tumor CpG Islands Neurofibromin 2 Proto-Oncogene Proteins c-mdm2 Cell Line Genes, p16 Proto-Oncogene Proteins Tumor Necrosis Factor-alpha Chromosome Deletion Mice, Nude Breast Neoplasms Polymorphism, Single-Stranded Conformational Oncogenes Immunohistochemistry Repressor Proteins Proteins Adenocarcinoma Cell Cycle Proteins Microsatellite Repeats Amino Acid Sequence Neoplasms, Experimental Blotting, Western Ubiquitin-Protein Ligases Alleles Brain Neoplasms Phosphoric Monoester Hydrolases Transcription, Genetic Acid Anhydride Hydrolases Protein Binding DNA Mutational Analysis Chromosomes, Human, Pair 9 Cyclin-Dependent Kinase Inhibitor p21 Epigenesis, Genetic Adenomatous Polyposis Coli Protein Phenotype Lung Neoplasms Carcinoma, Squamous Cell Carcinoma, Renal Cell Ovarian Neoplasms Skin Neoplasms Genes, ras DNA Primers Azacitidine Mice, Inbred C57BL Gene Expression Profiling Protein-Serine-Threonine Kinases Transplantation, Heterologous Exons RNA, Small Interfering MicroRNAs Cyclin-Dependent Kinase Inhibitor p15 Carrier Proteins

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