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  • neuronal
  • The actomyosin system is considered to be responsible for the morphological changes, but how exactly it regulates oxidative stress-induced neuronal apoptosis and the distinctive functions of different myosin II isoforms remain unclear. (frontiersin.org)
  • Regulator
  • Maegen A. Ackermann and Aikaterini Kontrogianni-Konstantopoulos, "Myosin Binding Protein-C: A Regulator of Actomyosin Interaction in Striated Muscle," Journal of Biomedicine and Biotechnology , vol. 2011, Article ID 636403, 9 pages, 2011. (hindawi.com)
  • regulates
  • The actomyosin system is considered to be responsible for the morphological changes, but how exactly it regulates oxidative stress-induced neuronal apoptosis and the distinctive functions of different myosin II isoforms remain unclear. (frontiersin.org)
  • Regulation
  • We conclude that tight spatiotemporal regulation of myosin activity throughout successive rounds of ovulation shapes actomyosin network development and maintenance required for tissue function and animal fertility. (labroots.com)
  • molecular
  • Many attempts have thus been made to explain the molecular origin of the actomyosin motility. (eurekalert.org)
  • Andrei Khrennikov, Sergei Kozyrev, Alf Månsson, "Hierarchical model of the actomyosin molecular motor based on ultrametric diffusion with drift", Infin. (mathnet.ru)
  • cleft
  • Our results have identified a pre-force-generation actomyosin ADP·P i state, and suggest force generation may occur from a state not yet seen by crystallography in which the actin binding cleft and the nucleotide binding pocket are closed. (pnas.org)
  • The crystal structure of myosin V in the absence of nucleotide (rigor) demonstrated a closed conformation of the actin binding cleft ( 4 , 5 ), and this structure fit quite well into the electron microscopy image reconstructions of the actomyosin rigor complex ( 6 ). (pnas.org)
  • embryos
  • Despite our understanding of actomyosin function in individual migrating cells, we know little about the mechanisms by which actomyosin drives collective cell movement in vertebrate embryos. (sciencemag.org)
  • role
  • We further characterize the role of myosin activity in actomyosin network organization and show that both increased and decreased myosin activity alter network properties including connectivity, orientation, and anisotropy. (labroots.com)