Activity when tested serum bactericidal test. Medical search. Frequent questions

PVP-I 7% gargle/mouthwash was diluted 1:30 with water to a concentration of 0.23% (the recommended concentration for "real-life" use in Japan) and tested at room temperature under clean conditions [0.3 g/l bovine serum albumin (BSA), viruses only] and dirty conditions (3.0 g/l BSA + 3.0 ml/l erythrocytes) as an interfering substance for defined contact times (minimum 15 s). (springer.com)
The cells were isolated by a method previously described7 and then suspended in KrebsRinger phosphate (KRP) solution, pH 7.45, to which was added 0.006 M glucose and 0.35% bovine serum albumin (Sigma Chemicals, St. Louis, Missouri). (docksci.com)

Hyperimmune mouse serum raised against purified, recombinant OmpP4 did not promote bactericidal killing of 35000HP or phagocytosis by J774A.1 mouse macrophages in serum bactericidal and phagocytosis assays, respectively. (biomedcentral.com)
Migration experiments were carried out in Boyden chambers with bacterial chemotactic factor as the attractant, and bactericidal assays were done with Staphylococcus aureus and serum from an AB blood group donor as a source of opsonins. (docksci.com)
There are a variety of assays available to test immune function in the dog. (dvm360.com)

Results: regarding antimicrobial proprieties, the tested substances showed effective bacteriostatic and bactericide activity. (bvsalud.org)
This is further supported by the plants' anti-proliferative potential, bacteriostatic, bactericidal properties and also their ability to block bacterial efflux pump systems. (biomedcentral.com)

We determined the minimum bactericidal concentration (MBC) by incubating strain suspensions in Brucella broth with fetal bovine serum and samples at different concentrations in a final volume of 100 microl in a microaerobic atmosphere. (lacienciadelvino.com)

Despite the antimicrobial activity of macrophages, Mtb has been able to establish a series of strategies to handle the host immune machinery, interfere with, and arrest the phagosome maturation, counteract mycobactericidal molecules and ultimately survive in a hostile intracellular environment ( 8 - 10 ). (frontiersin.org)

A ≥ 5 log 10 (99.999%) decrease of bacteria and ≥ 4 log 10 (99.99%) reduction in viral titre represented effective bactericidal and virucidal activity, respectively, per European standards. (springer.com)

In addition, minimum bactericidal concentrations (MBC), lactate dehydrogenase (LDH) release assay and rhodamine 6G intake assay were used to ascertain the antibacterial activity. (biomedcentral.com)
Following single doses of 500 mg and 1000 mg, average peak serum concentrations were approximately 16 and 28 mcg/mL, respectively. (sdrugs.com)
Our results showed that LYSO-induced S. aureus bacteriostasis increased with increasing concentrations of baicalin, and that baicalin binding to LYSO synergistically increased the antibacterial activity of LYSO. (oncotarget.com)

Following doses of 250 mg, 500 mg, and 1 g, average peak serum levels of approximately 9, 18, and 32 µg/mL respectively were obtained at 1 hour. (druglib.com)

We investigated the in vitro bactericidal and virucidal efficacy of povidone-iodine (PVP-I) 7% gargle/mouthwash at defined dilution against oral and respiratory tract pathogens. (springer.com)
PVP-I 7% gargle/mouthwash showed rapid bactericidal activity and virucidal efficacy in vitro at a concentration of 0.23% PVP-I and may provide a protective oropharyngeal hygiene measure for individuals at high risk of exposure to oral and respiratory pathogens. (springer.com)
The drug exerts high in vitro activity against staphylococci (except penicillinase-producing strains), streptococci (groups A, C, G, H, L and M) and pneumococci. (nih.gov)
In vitro tests demonstrate that the cephalosporins are bactericidal because of their inhibition of cell-wall synthesis. (druglib.com)
In vitro antibacterial and cytotoxic activity of leaf extracts of Centella asiatica (L.) Urb, Warburgia salutaris (Bertol. (biomedcentral.com)
This is the first study to explore the inhibitory effects of compounds from P. frutescens on Trichophyton mentagrophytes and its mechanism of action coupled with the antifungal activity in vitro from network pharmacology, transcriptomics and proteomics. (biomedcentral.com)

Antibacterial activity of grape extracts on cagA-positive and -negative Helicobacter pylori clinical isolates. (lacienciadelvino.com)
The lowest concentration in broth, where the subculture on agar showed complete absence of growth, was considered the MBC.The Colorino extract showed the highest antibacterial activity against G21 strain (MBC=1.35 mg/ml), while Sangiovese and Carbernet MBCs were 4.0 mg/ml ca. (lacienciadelvino.com)
Resveratrol exhibited the highest antibacterial activity. (lacienciadelvino.com)
Extracts were assayed for antibacterial activity using the agar well diffusion and micro plate dilution assay. (biomedcentral.com)
The extracts further revealed a broad-spectrum antibacterial activity against bacterial strains used in the study. (biomedcentral.com)
Overall, the extracts had good antibacterial activity and anti-proliferative effects against selected cancerous cell lines. (biomedcentral.com)
Given the good antibacterial activity of the extracts the plants may act as an immune booster and prevent infection in immunosuppressed cancer patients. (biomedcentral.com)
The tea extracts and components displayed various degrees of antibacterial activity that may involve damage to the bacterial cell membrane and the chelation of iron. (nature.com)

Cefotetan, like other cephalosporins, has no activity against Chlamydia trachomatis. (globalrph.com)

Conclusion: silver nanoparticles proved to have antimicrobial activity against S. mutans, therefore, they may be an effective agent in the prevention of dental caries. (bvsalud.org)
Compounds having both anticancer and antimicrobial activity have promising therapeutic potential due to their selective cytotoxicity and their potential to reduce the occurrence of bacterial and fungal infections in immune-compromised cancer patients. (biomedcentral.com)

Out of the seven tested recombinant human RNases, we have identified two members, RNase3 and RNase6, which were highly effective against Mycobacterium aurum extra- and intracellularly and induced an autophagy process. (frontiersin.org)

Efficacy of Echinacea-Supplemented Feeding on Health and Immune Status of Horses Phytotherapeutic medication with immunemodulatory efficacy represent one possible alternative to general bactericidal or anti-inflammatory agents. (uni-muenchen.de)

Source of all serum proteins is from USDA inspected abattoirs located in the United States. (bdbiosciences.com)
The binding of ciprofloxacin to serum proteins is 20% to 40%, which is not likely to be high enough to cause significant protein binding interactions with other drugs. (theodora.com)

PVP-I was tested against Klebsiella pneumoniae and Streptococcus pneumoniae according to bactericidal quantitative suspension test EN13727 and against severe acute respiratory syndrome and Middle East respiratory syndrome coronaviruses (SARS-CoV and MERS-CoV), rotavirus strain Wa and influenza virus A subtype H1N1 according to virucidal quantitative suspension test EN14476. (springer.com)
PVP-I gargle/mouthwash diluted 1:30 (equivalent to a concentration of 0.23% PVP-I) showed effective bactericidal activity against Klebsiella pneumoniae and Streptococcus pneumoniae and rapidly inactivated SARS-CoV, MERS-CoV, influenza virus A (H1N1) and rotavirus after 15 s of exposure. (springer.com)

Absolute other hand, another study reported that the neutrophil count was calculated as fol- phagocytic activity of neutrophils was simi- lows: absolute value (neutrophils/mm3) = lar in women in the 1st and 2nd trimesters total leukocyte count (cells/mm3) × relative of pregnancy and non-pregnant women, but value (%) obtained from the differential significantly decreased during the 3rd tri- count [10]. (who.int)
Neutrophils which had no distinct reproductive age, indicating that the neu- fine filament (length but no breadth) con- trophils have a greater capacity for attach- necting the nuclear lobes were considered ment to microorganisms, and thus have band forms [10,11], young immature forms increased phagocytic activity [8]. (who.int)

In the bactericidal experiments, a hospital strain of Staphylococcus aureus was grown overnight in trypticase soy yeast broth (Difco Laboratories), separated by centrifugation, washed and resuspended in 0.9% sodium chloride to approximately 5.0 x l0. (docksci.com)
The antifungal activity of the candidates was detected by a broth microdilution method. (biomedcentral.com)

One such standardized procedure 2,4 which has been recommended for use with disks to test susceptibility of organisms to penicillin uses the 10 unit (U) penicillin disk. (nih.gov)
Should the reduced susceptibility of 10K strain be extended to all the cagA+ H. pylori isolates, which are endowed with cancer promoter activity, this observation may help explain why the organisms expressing CagA are more closely associated with atrophic gastritis and gastric carcinoma development. (lacienciadelvino.com)
One such standard procedure1,3 which has been recommended for use with disks to test susceptibility of organisms to Cefoxid uses the cephalosporin class (cephalothin) disk. (sdrugs.com)

Interpretation involves the correlation of the diameters obtained in the disk test with the minimum inhibitory concentration (MIC) for penicillin. (nih.gov)
We also verified the minimum bactericidal concentration (MBC) of the target products. (bvsalud.org)
General well-being, blood results, the plasma cortisol concentration as well as the serum concentration of immune globuline G were determined on Day 0, 10, 21, 28, 35, and 70. (uni-muenchen.de)
The concentration of several inflammatory mediators was measured in the serum of these patients, and levels of IFN-γ, IL-1β and IL-6 were found significantly increased before the treatment of acute brucellosis. (frontiersin.org)

both bacterial ghost vaccines (BGVs) were safe and effective, according to the results of the safety check tests and histopathological analysis. (biomedcentral.com)
When comparing the BGVs prepared using TX100 and TW80 methods, the use of TX100 as a new chemical treating agent for BGC production attained robust results in terms of shorter incubation time with the targeted cells and a strong immune response against S. flexneri 2b serotype ATCC 12022 in the IP challenge test. (biomedcentral.com)
Reports from the laboratory providing results of the standard single-disk susceptibility test with a 10 U penicillin disk should be interpreted according to the criteria provided in Table 1. (nih.gov)
N. farcinica is particularly important to distinguish since it has increased virulence and differs in its antimicrobial susceptibility test results and its epidemiology ( 16 , 126 ). (antimicrobe.org)
Reports have been limited to antimicrobial susceptibility test results of clinical isolates, usually from reference laboratories, animal studies and case summaries ( 19 , 78 ). (antimicrobe.org)
Determination of immuneglobuline G fostered serum results between 17.15 mg/ml and 26.82 mg/ml. (uni-muenchen.de)
Whether chosen according to culture results or not, drugs with the narrowest spectrum of activity that can control the infection should be used. (msdmanuals.com)

In H. influenzae , e (P4) stimulates production of bactericidal and protective antibodies and contributes to pathogenesis by facilitating acquisition of the essential nutrients heme and nicotinamide adenine dinucleotide (NAD). (biomedcentral.com)

Des experiences de migration ont 6t6 r6alis6es dans des chambres de Boyden utilisant un facteur de chimiotaxie bacterien comme stimulant, et des essais d'effet bact6ricide ont .t6 faits sur Staphylococcus aureus avec le serum d'un donneur de type AB From the University of Western Ontario, London, Ont. (docksci.com)

MEFOXIN contains approximately 53.8 mg (2.3 milliequivalents) of sodium per gram of cefoxitin activity. (rxlist.com)
CEFOTAN™ (cefotetan for Injection, USP) is supplied in vials containing 80 mg (3.5 mEq) of sodium per gram of cefotetan activity. (globalrph.com)

The use of antibiotic disk susceptibility test methods which measure zone diameter give an accurate estimation of antibiotic susceptibility. (sdrugs.com)
Cultures and antibiotic susceptibility testing are essential for selecting a drug for serious infections. (msdmanuals.com)
Synergism is usually defined as a more rapid and complete bactericidal action from a combination of antibiotics than occurs with either antibiotic alone. (msdmanuals.com)

In the present work, we tested the antioxidant and antimicrobial activities of hydro-alcoholic extracts from Colorino, Sangiovese and Cabernet Sauvignon grape cultivars against H. pylori G21 (cagA-negative, cagA-) and 10K, (cagApositive, cagA+) clinical isolates. (lacienciadelvino.com)

and (2) The tuberculin skin test. (cdc.gov)
Adding to CDC's current recommendations for administering isoniazid preventive therapy to HIV-infected persons with positive tuberculin skin tests and to HIV-infected persons who were exposed to patients with infectious TB, this report also describes in detail the use of new short-course (i.e., 2 months) multidrug regimens (e.g., a rifamycin, such as rifampin or rifabutin, combined with pyrazinamide) to prevent TB in persons with HIV infection. (cdc.gov)

These antigens were expressed and probed with acute and convalescent serum from microbiologically confirmed Shigella infections. (biomedcentral.com)
For empiric treatment of serious infections that may involve any one of several pathogens (eg, fever in neutropenic patients) or that may be due to multiple pathogens (eg, polymicrobial anaerobic infection), a broad spectrum of activity is desirable. (msdmanuals.com)

It has no activity against Pseudomonas spp. (druglib.com)
It has no activity against Pseudomonas species and Acinetobacter calcoaceticus (formerly Mima and Herellea species). (sdrugs.com)

Here, we tested the hypothesis that, like its homolog, H. ducreyi OmpP4 contributes to virulence and stimulates production of bactericidal antibodies. (biomedcentral.com)
To test whether OmpP4 was necessary for virulence in humans, eight healthy adults were experimentally infected. (biomedcentral.com)
Additional virulence properties associated with F. nucleatum include hemolytic activity 8 and the ability to produce hydrogen sulfide (H 2 S) 9 . (nature.com)

However, a higher rate of acute toxicity (severe cutaneous toxicity and need for nutritional support) was found for RT-Cx, with 11% of harmful death and 13% of discontinuation rate of RT 0% of CRT group (33.3%, 15.1%) were detected.51 Recently, two randomized phase?III tests, RTOG 1016 and De-ESCALaTE, investigated the substitution of cisplatin with Cx in individuals with advanced HPV? (siamtech.net)

TPEx regimen is effective and might become substitute for PFExPanitumumabPRISMIIPanitumumab in monotherapyR/MLimited activity in previously treated patientsSPECTRUMIIICisplatin and 5-FU? (siamtech.net)

Neither hyperthermia nor any of the drugs tested affected PMNL viability adversely, but sodium salicylate and phenacetin suppressed PMNL migration. (docksci.com)
A report of "Intermediate" indicates that the result should be considered equivocal, and, if the microorganism is not fully susceptible to alternative, clinically feasible drugs, the test should be repeated. (druglib.com)
Although drugs within each class share structural and functional similarities, they often have different pharmacology and spectra of activity. (msdmanuals.com)

Penicillin V exerts a bactericidal action against penicillin-sensitive microorganisms during the stage of active multiplication. (nih.gov)

The respiratory burst activity of granulocytes was measured as well as the plasma's anti-oxidative potential. (uni-muenchen.de)
The granulocytes' respiratory burst activity was determined on Days 0, 21, and 35 for ten horses at a time from the Echinacea-group as well as the control group. (uni-muenchen.de)

In this work, we have tested the human canonical members of the RNase family using a spot-culture growth inhibition assay based mycobacteria-infected macrophage model for evaluating their anti-tubercular properties. (frontiersin.org)

The key findings of the present study manifested that rosmarinic acid, a medicinal compound extracted from P. frutescens , had pharmacological activity in inhibiting the growth of Trichophyton mentagrophytes by affecting its enolase expression to reduce metabolism. (biomedcentral.com)

Immunized mice sera showed a significant increase in serum bactericidal activity of both preparations (TX100 = 40% and TW80 = 56%) compared to the non-immunized challenged group (positive control). (biomedcentral.com)
Still, a causal connection to the Echinaceasupplement could not be concluded, because tests showed no significant differences between the Echinacea-group and the control group. (uni-muenchen.de)

Here we tested the effects of baicalin on the activity of LYSO using the S. aureus mastitis mouse model and neutrophilic granulocyte model of S. aureus infection. (oncotarget.com)

Neurosyphilis, quite directly, is defined as a CSF WBC count of 20 cells/µL or greater or a reactive CSF Venereal Disease Research Laboratory (VDRL) test result. (medscape.com)

In our quest to find new antimicrobial agents with potent anticancer activity, the biological potential of leaves from the three medicinal plants Centella asiatica , Warburgia salutaris and Curtisia dentata as used by Zulu traditional healers for the treatment of cancer is investigated. (biomedcentral.com)
Ancient books of Traditional Chinese Medicine and modern pharmacological studies have shown that it has potential anti-fungi activity. (biomedcentral.com)

Studies of various medicinal plants and other natural products from nature have shown the anti-proliferative, cytostatic and cytotoxic activities of various phytochemicals against different cancer cells [ 3 ]. (biomedcentral.com)

Hence it appears PMNL function is similar at 370 and 400C but that some commonly used antipyretics have an adverse effect on PMNL activity. (docksci.com)

Anatomy1

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Analytical, Diagnostic and Therapeutic Techniques and Equipment1

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Bovine serum a2

Assays3

Bacteriostatic2

Determined the minimum bactericidal1

Macrophages1

Virucidal activity1

Concentrations3

Average peak serum1

Vitro6

Antibacterial activity8

Cephalosporins1

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Streptococcus2

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Pseudomonas2

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Drugs3

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Trichophyton1

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