Reactive speciesPhagocytosis and respiratory burstNeutrophil respiNeutrophilsPhagocyticPhagocytesOxidative burstMacrophagesPathogensMicrobicidalGranulocytesAnti-inflammatoryStimulatePolymorphonuclearTumorSpeciesSerumTractPhrenicInfectionAntioxidantDiseaseRobustBacteriaProteinsResponseInfectionsProteinSymptomsComplementEnzyme activityTissuesPhosphataseInhibitoryTotalLactateCellsControlOxygenProductionImportanceQuality of lRapid
Reactive species1
- ONO2− The exposure to these reactive species in the respiratory burst results in pathology. (wikipedia.org)
Phagocytosis and respiratory burst1
- Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line. (umassmed.edu)
Neutrophil respi2
- During experimental peritonitis, heat sterilized PD fluids inhibited the neutrophil respiratory burst response of intraperitoneal neutrophils. (gu.se)
- this form is caused by an inhibitory mutation in Rac2, which regulates activity of the neutrophil respiratory burst and actin assembly. (medscape.com)
Neutrophils4
- Myeloid cells, including macrophages and neutrophils, are especially implicated in the respiratory burst. (wikipedia.org)
- Myeloid cells generated under these conditions, although similar to neutrophils and monocytes in morphology and phenotype, have different genomic and biochemical profiles and functional activity. (aacrjournals.org)
- In combination with experimental peritonitis, heat sterilized PD fluid compared to filter sterilized, inhibited the CINC-1 release and the recruitment of neutrophils to the peritoneal cavity without affecting the intraperitoneal complement activation.The results of the present thesis indicate that addition of LMWH to the PD fluid improves ultrafiltration, probably by blocking C5a activity. (gu.se)
- The 'respiratory burst' of phagocytes such as neutrophils generates superoxide which forms H2O2 by dismutation. (brioglobal.com)
Phagocytic6
- They are phagocytic, and the respiratory burst is vital for the subsequent degradation of internalised bacteria or other pathogens. (wikipedia.org)
- In non-phagocytic cells, oxidative burst products are used in intracellular signalling pathways. (wikipedia.org)
- Flow cytometry analyses of phagocytic and respiratory burst activities and cytochemical characterization of leucocytes isolated from wrasse (Labrus bergylta A.). Fish and Shellfish Immunology. (uib.no)
- Phagocytic activity, reactive oxygen species production, reactive nitrogen species production, myeloperoxidase, lysozyme activity, and total immunoglobulins were tested before and after challenge. (int-res.com)
- Therefore, the present study aimed to evaluate the influence of HMB on the chemotactic activity (MIGRATEST® kit), phagocytic activity (PHAGOTEST® kit) and oxidative burst (BURSTTEST® kit) of monocytes and granulocytes in the peripheral blood of calves by flow cytometry. (researchsquare.com)
- Results An analysis of granulocyte and monocyte chemotactic activity and phagocytic activity revealed significantly higher levels of phagocytic activity in calves administered HMB than in the control group, expressed in terms of the percentage of phagocytising cells and mean fluorescence intensity (MFI). (researchsquare.com)
Phagocytes1
- The results indicate that OVT activates the functions of phagocytes as measured by the production of nitric oxide, interleukin-6, matrix metalloproteinase, and respiratory burst activity. (usda.gov)
Oxidative burst3
- Respiratory burst (or oxidative burst) is the rapid release of the reactive oxygen species (ROS), superoxide anion (O− 2) and hydrogen peroxide (H 2O 2), from different cell types. (wikipedia.org)
- The Flow Cytometric CellProbe Oxidative Burst Test was used to determinate if respiratory burst occurred or not and what its severity was after a 4 h incubation with propolis extracts (0 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 2.5 mg/mL, and 5 mg/mL). (tubitak.gov.tr)
- At the 5 mg/mL concentration, the percentages of fluorescence positivities of DCFH, PMA Oxidative Burst Test were observed as 28 ± 0.316% and 27 ± 0.374% for untreated and PMA-stimulated PMNLs, respectively. (tubitak.gov.tr)
Macrophages1
- The effects on the respiratory burst response following priming with lipopolysaccharide were assessed in macrophages treated for 30min. (cdc.gov)
Pathogens3
- As many microbicidal products are formed during respiratory burst, the importance of individual molecules in killing invading pathogens is not wholly understood. (wikipedia.org)
- Jacobs MRFelmingham DAppelbaum PCGruneberg RNAlexander Project Group, The Alexander Project 1998-2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. (jamanetwork.com)
- Most important, all healthcare settings need to re-emphasize the importance of basic infection control measures, including hand hygiene, for the control of SARS-CoV and other respiratory pathogens. (cdc.gov)
Microbicidal1
- This impairment in killing is caused by any of several defects in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme complex, which generates the microbicidal respiratory burst. (medscape.com)
Granulocytes2
- The respiratory burst activity of granulocytes was measured as well as the plasma's anti-oxidative potential. (uni-muenchen.de)
- The granulocytes' respiratory burst activity was determined on Days 0, 21, and 35 for ten horses at a time from the Echinacea-group as well as the control group. (uni-muenchen.de)
Anti-inflammatory1
- It was concluded that DMSO extracts of Turkish propolis may exhibit anti-inflammatory activities by reducing respiratory burst and secreting PMN elastase. (tubitak.gov.tr)
Stimulate2
- Campos-Pérez, JJ, Ellis, AE & Secombes, CJ 1997, ' Investigation of factors influencing the ability of Renibacterium salmoninarum to stimulate rainbow trout macrophage respiratory burst activity ', Fish and Shellfish Immunology , vol. 7, no. 8, pp. 555-566. (elsevierpure.com)
- Phorbol myristate acetate was used to stimulate respiratory burst. (tubitak.gov.tr)
Polymorphonuclear1
- Polymorphonuclear leukocytes (PMNLs) use both oxygen-dependent (respiratory burst) and oxygen-independent mechanisms (releasing proteolytic enzymes such as elastase) to destroy infectious agents. (tubitak.gov.tr)
Tumor2
- The effects on lavagate cellularity, albumin, tumor necrosis factor alpha (TNFa), and interleukin-1beta (IL1b) concentrations, and lactate- dehydrogenase (LDH) and beta-n-acetyl-glucosaminidase (NAG) activity were determined. (cdc.gov)
- The observations of the accumulation in spleens and tumors of large numbers of these cells with potent immune-suppressive activity were readily reproducible in most murine tumor models. (aacrjournals.org)
Species4
- Future studies should investigate different concentrations of carvacrol as well as its antifungal activity in different fish species. (int-res.com)
- However, phagocytosis can also activate the respiratory burst, which produces toxic reactive oxygen species (ROS). (frontiersin.org)
- Antibodies from UC patients greatly enhanced the respiratory burst in PMN, in response to individual bacterial species. (bmj.com)
- Streptococcus pneumoniae is a common bacteria of the commensal flora and together with other bacterial species, colonizes the nasopharyngeal niche and upper respiratory tract. (biomedcentral.com)
Serum2
- Opsonisation of R. salmoninarum with serum factors also increased the respiratory burst, but no difference was found between normal serum and heat-inactivated serum. (elsevierpure.com)
- Serum lysozyme activity increased with increasing JP level (p = 0.002), but the total immunoglobulin value was significantly higher in fish fed JP 100. (trjfas.org)
Tract2
- In addition, cross-sectional studies have shown increased microbiological colonisation of the lower respiratory tract during exacerbations of COPD compared with the stable state 15 , 16 . (ersjournals.com)
- Streptococcus pneumoniae is a widely distributed commensal Gram-positive bacteria of the upper respiratory tract. (biomedcentral.com)
Phrenic6
- At the core of respiratory circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing, and phrenic motor neurons (MNs), which provide the final motor output that drives diaphragm muscle contractions during inspiration. (elifesciences.org)
- Both MN- and Dbx1-specific cadherin inactivation in mice during a critical developmental window results in perinatal lethality due to respiratory failure and a striking reduction in phrenic MN bursting activity. (elifesciences.org)
- surprisingly, however, cell body position appears to be dispensable for the targeting of phrenic MNs by descending respiratory inputs. (elifesciences.org)
- Newborn mice in which phrenic motor neurons lacked a specific combination of cadherins experienced respiratory failure, showing that these proteins were needed for breathing circuits to develop normally. (elifesciences.org)
- Electrical activity recorded from these cells showed that phrenic motor neurons lacking cadherins could not receive the signals required to activate the breathing muscles. (elifesciences.org)
- Because another growth/trophic factor that signals via a receptor tyrosine kinase (brain derived neurotrophic factor) elicits a long-lasting facilitation of respiratory motor activity in the phrenic nerve, we tested the hypothesis that VEGFA-165 elicits similar phrenic motor facilitation (pMF). (jneurosci.org)
Infection2
- Post visual alerts (in appropriate languages) at the entrance to outpatient facilities (e.g., emergency departments, physicians' offices, outpatient clinics) instructing patient and the persons who accompany them to: 1) inform healthcare personnel of symptoms of a respiratory infection when they first register for care, and 2) practice respiratory hygiene/cough etiquette . (cdc.gov)
- During periods of increased respiratory infection in the community, offer masks to persons who are coughing. (cdc.gov)
Antioxidant5
- Effects of a 50 Hz electric field on plasma lipid peroxide level and antioxidant activity in rats med. (emf-portal.org)
- The Mimosa pollen sample displayed the highest antioxidant activity. (blogspot.com)
- There was good correlation between antioxidant activity and total phenolics. (blogspot.com)
- The order of effectiveness of the pollen samples in regard to antioxidant activity was determined and the most effective extraction solvents are discussed. (blogspot.com)
- However, the over production of oxygen free radicals in sperm membrane decreases the antioxidant defense activity thereby leading to low sperm motility and viability, DNA fragmentation and protein denaturation. (scialert.net)
Disease1
- Pneumococcal colonization is mostly asymptomatic, but can progress to respiratory or even systemic disease, causing the majority of community-acquired pneumonia and invasive diseases such as meningitis and bacteremia. (biomedcentral.com)
Robust3
- This activation is relatively short-lived and results in robust phagocytosis, respiratory bursts, and the release of proinflammatory cytokines. (aacrjournals.org)
- Here, we show that coordinated activity of a type I cadherin (N-cadherin) and type II cadherins (Cadherin-6, -9, and -10) is required in both MNs and Dbx1-derived neurons to generate robust respiratory motor output. (elifesciences.org)
- Our findings demonstrate that type I and II cadherins function cooperatively throughout the respiratory circuit to generate a robust breathing output and reveal novel strategies that drive the assembly of motor circuits. (elifesciences.org)
Bacteria1
- Changes in mucosal bacteria, and a switch from internal to surface antigen/antibody reactivity of a predominantly IgG1 type, leads to greater opsonisation of the respiratory burst in PMN, providing a mechanism for maintaining the inflammatory state in UC. (bmj.com)
Proteins2
- The analysis of Cdc42 and Rac function in evolutionarily distant organisms is useful as a tool to uncover the basic activities of these proteins. (biomedcentral.com)
- This activity is strongly conserved and probably represents a primordial function of these proteins. (biomedcentral.com)
Response2
- The multifunctional activity of the humoral immune response remained for at least 6 months after vaccination and was comparable to that of naturally acquired anti-MSP1 antibodies from semi-immune adults from Kenya. (nature.com)
- Metronidazole selectively radiosensitizes of metronidazole (in a range of therapeutic hypoxic cells without influencing the ra- concentrations) on PMN-generated free diation response of normal well-oxygenated radicals during phagocytosis activity in cells [ 5,7-9 ]. (who.int)
Infections1
- To address this deficiency, CDC is incorporating measures to prevent the transmission of all respiratory infections, beginning at the first point of contact with a potentially infected person, as one component of Standard Precautions in healthcare settings (see Appendix I1 and Guideline for Isolation Precautions in Hospitals ). (cdc.gov)
Protein1
- Altered protein function includes changes in enzyme catalytic activity, cytoskeletal organisation and cell signal transduction. (wikipedia.org)
Symptoms2
- However, the mystery of patients with these clinical symptoms (despite normal phosphatase activity) remained unsolved until 1978, when Narisawa et al identified a defect in intracellular transport of the enzyme substrate. (medscape.com)
- For many patients with chronic respiratory disorders, medical therapy only partially allays the symptoms and complications of the disorder. (msdmanuals.com)
Complement1
- The complement system influence the activity of numerous cells, tissues and physiological mechanism of the body. (dadamo.com)
Enzyme activity1
- [ 1 ] Two of the patients had almost total deficiency of hepatic glucose-6-phosphatase, whereas the remaining 4 had normal enzyme activity. (medscape.com)
Tissues1
- Use tissues to contain respiratory secretions. (cdc.gov)
Phosphatase1
- The possible involvement of RLO acid phosphatase as the inhibitor of respiratory burst was assessed. (ifremer.fr)
Inhibitory4
- Quorum sensing (QS) inhibitory activity of 29 unifloral honeys was evaluated using the bacterial model Cromobacterium violaceum. (blogspot.com)
- However, chestnut and linden honey samples showed the highest inhibitory activity , while orange and rosemary were less effective in inhibiting QS. (blogspot.com)
- When honey samples from the same floral origin obtained from different geographical regions were compared, they showed similar QS inhibitory activity. (blogspot.com)
- Thus, one of the factors which influence the inhibitory activity could be derived from the floral origin, independently of the geographic location. (blogspot.com)
Total1
- It was observed that unifloral honey samples showed "non-peroxide" anti-QS activity, which was not linearly correlated with total and individual phenolic compounds. (blogspot.com)
Lactate1
- An observation in neoplastic cellular transformation, characterized by an increased glucose uptake via glycolytic activities resulting in an increased LACTATE production under aerobic microenvironment. (bvsalud.org)
Cells1
- in particular, it is still unclear exactly how the two main types of nerve cells which form respiratory circuits start to 'talk' to each other. (elifesciences.org)
Control1
- Plasticity is a hallmark of the respiratory control system, including plasticity in spinal respiratory motor nuclei ( Mitchell and Johnson, 2003 ). (jneurosci.org)
Oxygen2
- Respiratory burst requires a 10 to 20 fold increase in oxygen consumption through NADPH oxidase (NOX2 in humans) activity. (wikipedia.org)
- Furthermore, because VEGFA-165 expression is hypoxia sensitive, it may play a role in respiratory plasticity after prolonged exposures to low oxygen. (jneurosci.org)
Production1
- Phagocytosis may still occur, but without proper functioning NOX2, there is no superoxide production, and therefore no respiratory burst. (wikipedia.org)
Importance1
- The C-terminal arginine in the molecule of C3a is of fundamental importance for its biological activity. (dadamo.com)
Quality of l1
- Secondary efficacy parameters included moderate (treatment with antibiotics and/or systemic corticosteroids) and/or severe (requiring hospitalisation) exacerbations and quality of life as measured by the St George's Respiratory Questionnaire. (ersjournals.com)
Rapid1
- slower brain waves, with occasional bursts of rapid brain waves. (medlineplus.gov)