Activity of thymol and carvacrol. Medical search. Frequent questions

Two of oregano's compounds, thymol and carvacrol, have potent antibacterial properties. (sikhnet.com)
Several chemical compounds, synthetic or from natural sources, such as the phenothiazines, and natural products, have direct activity against many species of bacteria, enhancing the activity of a specific antibiotic, reversing the natural resistance of specific bacteria to given antibiotics, promoting the elimination of plasmids from bacteria and inhibiting transport functions of the plasma membrane in regard to given antibiotics. (springer.com)
The enhancement of antibiotic activity or the reversal of antibiotic resistance by natural or synthetic non-conventional antibiotics affords the classification of these compounds as modifiers of antibiotic activity. (springer.com)
The most common compounds found in oregano are thymol and carvacrol. (live-live.com)
Application of proper types of surfactants was crucial for achieving optimum antifungal activity of compounds, thus emphasizing the importance of compound-compound or surfactant specificity during antifungal application. (usda.gov)
Out of twenty-one GRAS compounds examined (Clinical Laboratory Standards Institute protocol), five compounds showed the highest antifungal activity, viz. (usda.gov)
Carvacrol and thymol are related phenolic compounds found in essential oils of thyme and oreganum [ 8 ]. (annexpublishers.co)
Carvacrol and its isomer, thymol, are natural compounds that act against several diseases, including cancer. (bvsalud.org)
Because of the antimicrobial compounds (mainly thymol and carvacrol) found in the essential oil, we believe that the endophytic microorganisms found in L. sidoides are selected to live in different parts of the plant. (biomedcentral.com)
When it comes to its medicinal contents, oregano contains an impressive array of beneficial compounds including vitamins A and C, minerals like calcium and potassium , and antioxidants such as rosmarinic acid and thymol. (agraryo.com)
Oregano contains compounds such as carvacrol and thymol, which have antimicrobial properties. (agraryo.com)
The most lethal among such compounds was thymol from garden thyme (Thymus vulgaris) Feeding deterrence was determined using a cabbage leaf disk choice test. (iwerliewen.org)
The carvacrol and thymol compounds make oregano oil a powerful antiviral and antibacterial. (greenlivingtribe.com)

u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClove\u003c\/strong\u003e - Rich in eugenol the major constituent of cloves, was investigated for its antiviral activity by several research groups. (live-live.com)
Eugenol also showed antiviral activity against the influenza A virus (IAV), being able to inhibit IAV replication. (live-live.com)
Clove - Rich in eugenol the major constituent of cloves, was investigated for its antiviral activity by several research groups. (live-live.com)
The major components of these essential oils, namely, thymol, carvacrol and eugenol, showed the strongest bacterial activity at very low concentrations. (scialert.net)
This includes terpenoid phenols carvacrol, thymol, and eugenol. (balanceone.com)
The use of the plant-derived, GRAS-status molecules, caprylic acid, trans-cinnamaldehyde, eugenol, carvacrol and thymol as feed supplements for reducing cecal and/or oviduct populations of S. Enteritidis and C. jejuni in chickens will be addressed. (zootecnicainternational.com)
Based on the in vitro screening of antibacterial activity of several plant-derived antimicrobials (PDAs) on Salmonella and Campylobacter , we found four molecules with potential to inactivate these pathogens in poultry: trans- cinnamaldehyde (TC), eugenol, carvacrol and thymol. (zootecnicainternational.com)
Eugenol is an active ingredient in the oil from cloves ( Eugenia caryophillis ) and the antibacterial activity of clove oil and eugenol has been well documented. (zootecnicainternational.com)

Several studies show that the primary constituents in the plant, thymol and carvacrol, also demonstrate potent antioxidant activity. (herbalmusings.com)
Its antiseptic qualities come from its potent volatile oils, thymol and carvacrol, which have been shown to inhibit growth of Pseudomonas and Staphylococcus in culture (although it is unclear if this action takes place inside a living organism). (untrainedhousewife.com)
Other studies report that each of oregano extract's major components has potent antifungal activity. (balanceone.com)
In vitro, carvacrol appears to be more potent than thymol. (bvsalud.org)
Although, a wide range of bioactivities such as anticancer, antioxidant, and antimicrobial has been identified for carvacrol, however, among all therapeutic properties it possesses a potent antimicrobial activity. (ac.ir)

EOs showed a broad range of antimicrobial activity against all bacteria except P. aeruginosa . (scielo.br)
In this study an ethanol extract of Turnera ulmifolia L. and chlorpromazine were tested for their antimicrobial activity alone or in combination with aminoglycosides against an MRSA strain. (springer.com)
Many plants have been evaluated not only for direct antimicrobial activity, but also as a resistance-modifying agent [ 13 ]. (springer.com)
Antioxidant and antimicrobial activity of Satureja montana L. extracts. (herbalmusings.com)
This study showed that Z. multiflora oil has significant antimicrobial activity against clinical isolates of S. aureus, especially MRSA, and might be useful in controlling MRSA infections. (unboundmedicine.com)
TC possesses antimicrobial activity towards a wide range of foodborne pathogens, including Gram-positive and Gram-negative bacteria. (zootecnicainternational.com)
Twelve fungal samples of A. flavus were used and the antimicrobial activity of carvacrol was tested against them using the minimum inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) according to the broth microdilution procedure. (ac.ir)
Together the results demonstrated that carvacrol not only exhibited antimicrobial activity against A. flavus but also reduced its gene expression level. (ac.ir)
Antimicrobial activity of the essential oil from Lippia sidoides , carvacrol and thymol against oral pathogens. (ac.ir)

The warm, peppery flavor and aroma of winter savory is due to carvacrol, the same phenol that lends oregano oil its antibacterial, antifungal and antiviral properties. (herbalmusings.com)
Oregano oil contains two naturally-occurring antimicrobial agents, carvacrol and thymol. (balanceone.com)
Repeatedly, it has been shown, oregano oil and its active components, including carvacrol and thymol, have demonstrated great powers against inflammation. (cassingram.com)
This proved that the oregano oil component modified the activity, that is more towards normal, during a crisis event. (cassingram.com)
Oregano oil promotes white blood cell production and activity. (greenlivingtribe.com)

Extraction of EO-JC was performed by use of hydrodistillation using a Clevenger-type apparatus, and the EOs were analyzed by gas chromatography coupled with mass spectrometry (GC-MS). Antifungal activity of EO-JC was evaluated by the use of solid-state diffusion (disc method) and microdilution to determine the minimum inhibitory concentration (MIC), against three strains of fungus, Aspergillus niger , Aspergillus flavus, and Fusarium oxysporum . (hindawi.com)
The antifungal activity of EO-JC on solid media exhibited inhibitions in the range of 49% to 87%, and MIC was between 3.125 and 7.80 μ g EO-JC/mL. (hindawi.com)
EOs displayed divergent degrees of antifungal activity, and carvacrol was the most effective against the tested yeasts. (int-res.com)
Future studies should investigate different concentrations of carvacrol as well as its antifungal activity in different fish species. (int-res.com)
Schlosser I, Prange A. Antifungal activity of selected natural preservatives against the foodborne molds Penicillium verrucosum and Aspergillus westerdijkiae . (ac.ir)
Antifungal activity and mechanism of action of carvacrol and thymol against vineyard and wine spoilage yeasts. (ac.ir)
Ocak I, Çelik A, Özel MZ, Korcan E, Konuk M. Antifungal activity and chemical composition of essential oil of Origanum hypericifolium . (ac.ir)
Ocak I. Antifungal activity and chemical composition of essential oil of Origanum hypericifolium . (ac.ir)

Antimicrobial and Cytotoxic Activities of Origanum Essential Oils. (zanehellas.com)
Composition and antioxidant activity of the essential oil of Origanum glandulosum Desf. (scholarsresearchlibrary.com)

Yin HB, Chen CH, Kollanoor-Johny A, Darre MJ, Venkitanarayanan K. Controlling Aspergillus flavus and Aspergillus parasiticus growth and aflatoxin production in poultry feed using carvacrol and trans-cinnamaldehyde. (ac.ir)
Yin H-B, Chen C-H, Kollanoor-Johny A, Darre MJ, Venkitanarayanan K. Controlling Aspergillus flavus and Aspergillus parasiticus growth and aflatoxin production in poultry feed using carvacrol and trans-cinnamaldehyde. (ac.ir)

Salicylic acid (2 mmol/L) or a mixture of thymol (0,5 % w/v) and cinnamaldehyde (0,5 % w/v) were added to the starch film forming solution. (gob.ec)

However, to our knowledge, the anticancer activity of OEO has not been reported. (irost.org)
Therefore, we used OEO and its main component, thymol, to explore their effects on cell growth inhibition and anticancer activity. (irost.org)

PCR-DGGE profile analysis and principal component analysis showed that the total bacteria, Alphaproteobacteria, Betaproteobacteria and fungi were influenced not only by the location within the plant (leaf vs. stem) but also by the presence of the main components of the L. sidoides essential oil (thymol and/or carvacrol) in the leaves. (biomedcentral.com)

Antioxidant activities of the supercritical and conventional Satureja montana extracts. (herbalmusings.com)
Chemical Composition and Cytotoxic and Antioxidant Activities of Satureja montana L. Essential Oil and Its Antibacterial Potential against Salmonella Spp. (herbalmusings.com)
Title: In vitro antibacterial, antifungal, and antioxidant activities of the essential oil and methanol extracts of herbal parts and callus cultures of Satureja hortensis L. (sciencewatch.com)
Asian Pacific journal of tropical medicine 4 (8), 614-618 A study made in Italy on anti-plasmodial and insecticidal activities of essential oils of aromatic plants growing in the Mediterranean area showed that thymol from savory (Satureja thymbra) showed the highest larvicidal and adulticidal activities. (iwerliewen.org)

thymol ( Thymus vulgaris ct. (theherbalacademy.com)
Composition and microbial activity of thyme (Thymus algeriensis genuinus) essential oil. (pillarsofwellness.com)

Despite having a limited effect on L929 normal cells, OEO/thymol induced cytotoxicity in MDA-MB231 breast cancer monolayers (2D) and to a lesser extent in MDA-MB231 spheroids (3D). (irost.org)
It was attested that carvacrol and thymol induced apoptosis, cytotoxicity, cell cycle arrest, antimetastatic activity, and also displayed different antiproliferative effects and inhibition of signaling pathways (MAPKs and PI3K/AKT/mTOR). (bvsalud.org)

Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans. (zanehellas.com)
Significance and impact of study: In the wake of rising antimicrobial resistance, we envisage that carvacrol and thymol could be used to prevent biofilm formation by UPEC and to reduce its virulence. (dieselok.md)
The objective of this study was to verify the synergistic effect and activity against biofilm formation of the EO from M. divaricatum against bacteria associated with dental caries. (revistarebram.com)
The synergistic effect and activity against biofilm formation of the essential oil (EO) from M. divaricatum against bacteria associated with dental caries were observed. (revistarebram.com)

Indeed, OEO/thymol increased the Reactive Oxygen Species (ROS) level leading to mitochondrial membrane potential (MMP, ΔΨm) loss, caspase-3 activation and DNA damage caused S-phase cell cycle arrest. (irost.org)
Phagocytic activity, reactive oxygen species production, reactive nitrogen species production, myeloperoxidase, lysozyme activity, and total immunoglobulins were tested before and after challenge. (int-res.com)

Antibacterial activity of the oil was evaluated by microbroth dilution assay against clinical isolates of methicillin -resistant (MR) and methicillin-sensitive (MS) strains of S. aureus. (unboundmedicine.com)
The oil showed high antibacterial activity against MRSA and MSSA with minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values in the range of 0.25-1 and 0.5-2microl/ml, respectively. (unboundmedicine.com)
These phenols are possibly one reason that thyme oil is known for its antibacterial activity. (airborne.co.nz)
While some research has been done on antibacterial activity on Thyme honey, to date no significant difference to other New Zealand honeys has been shown. (airborne.co.nz)

Furthermore, immunoblotting studies revealed the activation of intrinsic and maybe extrinsic apoptosis pathways by OEO/thymol. (irost.org)

Of these, two are found in New Zealand in two separate populations, and the phenols Thymol and Carvacrol are represented differently in these two populations. (airborne.co.nz)

Forty-three used carvacrol, 19 thymol, and 15 studies tested both monoterpenes. (bvsalud.org)

Thymol is the strongest and comes close to pyrethrins. (iwerliewen.org)

This Research Front on ANTIOXIDANT ACTIVITY OF PLANT ESSENTIAL OILS from the field of Agricultural Sciences was selected for mapping from the list of Top Topics for August 2009 (data from the second bimonthly period of 2009). (sciencewatch.com)
The antioxidant activity of the essential oil was investigated by the use of β- carotene bleaching method. (scholarsresearchlibrary.com)

New thymol and carvacrol derivatives with the carbamate moiety were synthesized and their inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated. (bezmialem.edu.tr)
Of note, while 4I3M and its natural derivatives (thymol, carvacrol) were compatible with two out of three surfactants tested, the remaining surfactant antagonized the activity of 4I3M and its derivatives. (usda.gov)

Conclusions: Carvacrol and thymol exhibited antitumor and antiproliferative activity through several signaling pathways. (bvsalud.org)

The present study investigates the inhibitory eﬀect of carvacrol as an active compound against the growth of Aspergillus flavus , besides its effect on the expression of aflatoxin-related ( aflR ) gene. (ac.ir)
Carvacrol and thymol as potential preservatives against Aspergillus in maize grains. (ac.ir)

In this study, the chemical composition and antistaphylococcal activity of Zataria multiflora Boiss essential oil were evaluated, along with its synergistic activity with vancomycin. (unboundmedicine.com)

Reduced FI observed already at lower oregano inclusion level can be due to higher active ingredient content such as carvacrol. (researchgate.net)
Both the United States Environmental Protection Agency (EPA) in the USA and the Government of Canada have placed on the list of disinfectants with evidence for use against COVID-19 preparations with thymol as the active ingredient. (live-live.com)

Effect of thyme oil and thymol dietary supplementation on the antioxidant status and fatty acid composition of the ageing rat brain. (pillarsofwellness.com)

The essential oil was obtained by hydrodistillation from aerial parts of the plant and analyzed using GC and GC-MS. Thymol (38.7%), carvacrol (15.3%) and rho-cymene (10.2%) were the main components of the oil. (unboundmedicine.com)
In essential oil fractions obtained by hydrodistillation carvacrol and terpine-4-ol also showed some activity. (iwerliewen.org)

Add a few drops to a liquid soap\u003c\/p\u003e\n\u003ch3\u003eAnti-Viral benefits of these essential oils:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eThyme\u003c\/strong\u003e - Thymol and Calvacrol have antiviral (herpes simplex virus type I, human rhinoviruses and influenza viruses) properties. (live-live.com)
The main molecular mechanisms involved in the antiviral activity are direct inactivation. (live-live.com)
u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRosemary\u003c\/strong\u003e - \u003cspan data-mce-fragment=\"1\" class=\"ILfuVd\" lang=\"en\"\u003e\u003cspan data-mce-fragment=\"1\" class=\"hgKElc\"\u003eThe present in vitro studies revealed that rosemary extract exhibited antiviral activity against HSV-1 and HSV-2, along with antioxidant effects. (live-live.com)
Thyme - Thymol and Calvacrol have antiviral (herpes simplex virus type I, human rhinoviruses and influenza viruses) properties. (live-live.com)
Rosemary - The present in vitro studies revealed that rosemary extract exhibited antiviral activity against HSV-1 and HSV-2, along with antioxidant effects. (live-live.com)

Chemical Composition and Evaluation of Antifungal and Insecticidal Activities of Essential Oils Extracted from Jambosa caryophyllus (Thunb. (hindawi.com)
NPV, a product made from the major components of essential oils, showed a high anticlostridial activity. (scialert.net)
The researchers also report that the essential oil showed significant antioxidant and cytotoxic activity against A549 cell line, also known as human lung adenocarcinoma epithelial cell line. (herbalmusings.com)
The essential oil exhibited synergism with vancomycin and displayed the ability to enhance the activity of vancomycin. (unboundmedicine.com)
At nearly 66% concentration, carvacrol proved the most powerful compound in oregano essential oil for its antimicrobial and antibacterial properties. (ecowatch.com)
collected from Zighoud-Youcef (Eastern Algerian), was analyzed by GC and GC/MS. 18 Components representing 93.65% % of the essential oil were detected with thymol (70.59%), tert-butylbenzene (5.76%), carvacrol (5.44%) and g-terpinene (5.04%) as the major components. (scholarsresearchlibrary.com)
Dell'Agli M, Sanna C, Rubiolo P, Anti-plasmodial and insecticidal activities of essential oils of aromatic plants growing in the Mediterranean area, Malaria Journal 11 :219 Thymol appears to be a neuractive chemical which affects the flight motor activity and wing beat frequency in flies. (iwerliewen.org)
The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): A short review. (pillarsofwellness.com)
Carvacrol was found in essential oils of thyme, oregano, wild bergamot, and some other plants. (ac.ir)

For formulation purpose, synergism was further investigated between OG (showing the highest activity) and conventional preservatives. (usda.gov)

CONCLUSIONS: Liposomal amphotericin B showed the higher activity and efficacy against the two strains of C. guilliermondii, in contrast to the poor effect of fluconazole and anidulafungin. (who.int)

The results of MIC and MFC tests showed that carvacrol at 0.8 μg/ml and 3.5 μg/ml concentrations displayed antimicrobial activities on A. flavus , respectively. (ac.ir)

Kelly and SH-SY5Y neuroblastoma cells also exhibited a reduced proliferation rate after exposure to carvacrol (Kocal and Pakdemirli, 2020). (dieselok.md)

Anticlostridial activity was measured by determining the inhibition of bacterial growth. (scialert.net)
Indications of rumen microbial adaptation were observed in carvacrol and thymol as CH 4 significantly increased from almost complete inhibition at day 3 to almost 5 % of total gas at day 9. (annexpublishers.co)

The dietary additive of carvacrol significantly enhanced growth performance, all immunological parameters, and the RPS values (90%) compared to other treatments. (int-res.com)
Furocoumarins: a review of biochemical activities, dietary sources and intake, and potential health risks. (earthtokathy.com)

The effects of carvacrol and thymol on fermentation parameters suggested that these supplements lower CH 4 indirectly by suppressing overall fermentation whereas garlic oil selectively inhibits methanogens directly. (annexpublishers.co)

Carvacrol and thymol both significantly reduced tissue levels of interleukin-2. (cassingram.com)

This unique experimental model indicates that carvacrol seems promising not only for enhancing immunity and promoting fish growth, but also for controlling emerging fungal infections. (int-res.com)

2002). The Mechanism of Carvacrol-Evoked [Ca2+]i Rises and Non-ca2+-triggered Cell Death in OC2 Human Oral Cancer Cells. (dieselok.md)

and focused on the efficacy of one EO (carvacrol) on growth performance, non-specific immunity, and disease resistance of Nile tilapia Oreochromis niloticus against Cryptococcus uniguttulatus challenge. (int-res.com)
In other work, thymol oil and thymol microemulsions were studied for their efficacy in controlling Salmonella Enteritidis infection alone and in combination with sulfatrimethoprim antibiotics in broiler chickens (Hamed et al. (scite.ai)
AIMS: Evaluate the in vitro activity of anidulafungin in comparison to amphotericin B and fluconazole against different isolates of C. guilliermondii, and their efficacy in an immunosuppressed murine model of disseminated infection. (who.int)

Synthesis, anticholinesterase activity a. (bezmialem.edu.tr)

It is therefore suggested that extracts from Turnera ulmifolia could be used as a source of plant-derived natural products with resistance-modifying activity, constituting a new weapon against the problem of bacterial resistance to antibiotics demonstrated in MRSA strains. (springer.com)
The treatment with thymol oil determines the improvement of the general condition of the animals, through the bacterial balance established at the intestinal level. (scite.ai)

Specifically, the oil was found to markedly act with actions to block excessive cell growth, known as anti proliferative activity, while also it greatly inhibited markers of inflammation. (cassingram.com)

In-vitro evaluation of apoptotic effect of OEO and thymol in 2D and 3D cell cultures and the study of their interaction mode with DNA. (irost.org)
A 2013 study published in the journal PLoS ONE suggested that oregano exhibits anti-cancer activity, as the researchers concluded that oregano could treat and prevent breast cancer through preventing or slowing its progression. (selfgrowth.com)
A recent study suggests that carvacrol can kill up to 90% of herpes simplex type 1 viruses within an hour. (oneradionetwork.com)
65: 241- 248 An extensive study on the insecticidal properties of thymol is a thesis from the Iowa State University. (iwerliewen.org)

Anticarcinogenic and antiplatelet effects of carvacrol. (zanehellas.com)
Thus, this systematic review aimed to examine and synthesize the knowledge on the antitumor effects of carvacrol and thymol. (bvsalud.org)
Carvacrol Exhibits Anti-oxidant and Anti-inflammatory Effects against 1, 2-dimethyl Hydrazine Plus Dextran Sodium Sulfate Induced Inflammation Associated Carcinogenicity in the colon of Fischer 344 Rats. (dieselok.md)
doi:10.7287/peerj.9626v0.1/reviews/1, Soković, M., Glamoclija, J., and Ciric, A. Thymol also caused a decrease in cell viability of prostate cancer (PC-3 cell line), and provoked cytotoxic effects (Pathania et al. (dieselok.md)
Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms. (pillarsofwellness.com)

Los cromatogramas fueron elaborados en: Instituto de InvestigaciÃ³n en BioquÃ-mica y BiologÃ-a Molecular de la UNALM, 2014. (dieselok.md)

Oregano contains a powerful compound called carvacrol that allows it to fight bacteria due to its natural antibiotic properties. (ecowatch.com)
The RT-PCR result indicated that the expression level of aflR gene had decreased to 33% in the presence of carvacrol compared to 67% in the absence of the mentioned active compound. (ac.ir)

We concluded that rumen microbes adapted to carvacrol and thymol. (annexpublishers.co)
7 ], after applying carvacrol at a low dose (2.2 mg/l) in a continuous culture system suggested that rumen microbes could adapt to carvacrol. (annexpublishers.co)
Although carvacrol isn't a cure for herpes or cold sores, it has been shown to have some activity against the microbes that cause flare ups. (oneradionetwork.com)

Based on our GC/MS analysis, the basic ingredients of OEO are thymol, carvacrol, p -cymene and γ-terpinene. (irost.org)

Organisms4

Chemicals and Drugs7

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Compounds13

Eugenol8

Potent5

Antimicrobial activity9

Oregano oil5

Antifungal activity8

Origanum2

Trans-cinnamaldehyde2

Cinnamaldehyde1

Anticancer2

Sidoides1

Satureja4

Thymus2

Cytotoxicity2

Biofilm formation4

Reactive Oxygen2

Antibacterial activity4

Apoptosis1

Phenols1

Monoterpenes1

Strongest1

Antioxidant activity2

Derivatives2

Pathways1

Aspergillus2

Multiflora1

Active ingredient2

Thyme oil1

Hydrodistillation2

Antiviral5

Essential9

Preservatives1

Conclusions1

Concentrations1

20201

Inhibition2

Dietary2

Supplements1

Significantly1

Fungal infections1

Mechanism1

Efficacy3

Synthesis1

Bacterial2

Found1

Study4

Effects5

Molecular1

Compound2

Microbes3

Ingredients1