AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
Benzylidene CompoundsPiperidonesAnabasineAcetalsEchinochloaMolecular StructureDrug Screening Assays, AntitumorStructure-Activity RelationshipCell Line, TumorAntineoplastic AgentsFiltrationEncyclopedias as TopicUltraviolet RaysSunscreening AgentsKynureninePhotographyVena Cava Filters
Organic compoundsHeterocyclic compoundsCamphorAntimicrobialAminoSynthesisVitroDerivativesNovel seriesMoietyCondensationAntifungal activityBiological activitiesPotentInhibitorsAntibacterial activityMethodsNewlyEthanolAnticancerReadilyCytotoxicPharmacologicalFoundMASSAssayStrainsStudyExhibitEffectiveMaterialsTitleServeHighPositiveWaterTreatment
Organic compounds5
  • Many different organic compounds can serve as UV filters. (wikipedia.org)
  • Mol-Instincts supplies 35 constant properties of pure organic compounds. (molinstincts.com)
  • Mol-Instincts possesses 11 temperature-dependent properties of pure organic compounds. (molinstincts.com)
  • Carbohydrates are the most abundant class of organic compounds found in living organisms. (feinni.best)
  • Synthesis, Characterization and Evaluation of the Anti-cancer Activity of Silver Nanoparticles by Natural Organic Compounds Extracted from Cyperus sp. (actapharmsci.com)
Heterocyclic compounds4
  • Heterocyclic compounds have a crucial part in the metabolism of all biological cells. (ijpsr.com)
  • Humanity relies heavily on nitrogen-based heterocyclic compounds. (ijpsr.com)
  • Because the heterocyclic molecule is a component of many biological components, the usage of heterocyclic compounds in medicinal chemistry is growing by the day. (ijpsr.com)
  • Chemistry of Heterocyclic Compounds 52 (2016): 1. (actascientific.com)
Camphor1
  • The 4-methyl-benzylidene camphor was detected in the muscle tissue of trout in Swiss and German waters, while traces of Ethylhexyl methoxycinnamate and octocrylene were found in shellfish in the Mediterranean and Atlantic coasts of France. (wikipedia.org)
Antimicrobial6
  • The antimicrobial property of several benzimidazole compounds is summarised in this study. (ijpsr.com)
  • Many scientists developed benzimidazole-based compounds and tested their antimicrobial potential against number of bacterium types. (ijpsr.com)
  • She is especially interested in the search for antimicrobial compounds and has been working on peptidoglycan as an antibacterial target for 8 years. (degruyter.com)
  • All synthesized compound have been screened for in-vitro evaluation of antimicrobial activities by agar plate techniques. (actascientific.com)
  • The results indicated that all the synthesized 1, 3 thiazine derivatives shows considerable antimicrobial activities. (actascientific.com)
  • This study suggested that 1, 3-thiazine derivatives founded to have potent antimicrobial activity against the selected pathogenic organisms and posses more antimicrobial activities on gram negative (E. coli) bacteria than gram positive bacteria (S. aureus) . (actascientific.com)
Amino2
  • HCl to get2-(3-hydroxy-4-methoxy benzylidene amino phenyl amido)-6-fluoro-7-chloro-(1,3)- benzothiazole or Schiff's base. (ignited.in)
  • U. D. Uysal, D. Ercengiz, O. Karaosmanoğlu, B. Berber, H. Sivas, & H. Berber, "Theoretical and experimental electronic transition behaviour study of 2-((4-(dimethylamino)benzylidene)amino)-4-methylphenol and its cytotoxicity," J. Mol. (uns.ac.id)
Synthesis4
  • Synthesis and cytotoxic properties of novel (E)-3-benzylidene-7- methoxychroman-4-one derivatives. (irost.org)
  • It was found that these compounds readily undergo regioselective interrupted Nazarov cyclization with trapping chloride ion and an efficient method of the synthesis of d -annulated pentacyclic steroids based on this reaction was proposed. (mdpi.com)
  • Currently his research activity focuses on the design and synthesis of new antituberculotics. (degruyter.com)
  • In this regard, the present study reports the green synthesis of new benzaldazine and ketazine derivatives via the condensation of various carbonyl compounds (aldehydes and ketones with the 3-(1-hydrazineylideneethyl)-1H-indole using the grinding method with one drop of acetic acid). (dntb.gov.ua)
Vitro3
  • Thus, a novel series of 3-benzylidene-4-chromanones were synthesized and tested in vitro against human cancer cell lines. (irost.org)
  • In addition, a series of 2-(N-carbamoyl acetamide)-substituted 2,3-dihydrothiophene analogs were synthesized, and selected samples were chosen for testing their in vitro antibacterial and antifungal activities. (bvsalud.org)
  • All the derivatives are characterized by TLC and spectral analysis 1H NMR, 13 C NMR, IR, MASS. All the synthesized compounds were screened as in vitro anti-cancer, and anti-bacterial activity. (jyoungpharm.org)
Derivatives4
  • Furthermore, the anticancer activities of the reported azine derivatives were evaluated against colon, hepatocellular, and breast carcinoma cell lines using the MTT technique with doxorubicin as a reference medication. (dntb.gov.ua)
  • The findings suggested that the synthesized derivatives exhibited potential anti-tumor activities toward different cell lines. (dntb.gov.ua)
  • These results along with the structure-activity relationship (SAR) of the reported derivatives will pave the way for the design of additional azines bearing indole with potential anticancer activities. (dntb.gov.ua)
  • Sedef Atmaca Turkish Abstract Abstract Full Text PDF Similar Articles Mail to Editor Cardiovascular Properties of new Imidazolidin-2-one Derivatives with Local Anesthetic and Antiarrhythmic Activity #Librowski T. (actapharmsci.com)
Novel series1
  • A novel series of compound were synthesized 2-(9-chloro-2,3-dimethyl-6,7-dihydro-5 H -benzo[7]annulen-8- yl)-3-thiazolidin-4one (9a-i) (10a-i) and its scaffold. (jyoungpharm.org)
Moiety2
  • Compounds with heterocyclic moiety are important for life and are abundant in nature. (ijpsr.com)
  • The core structure of benzo[7] annulene contains a number of natural products, and this moiety is helpful in the treatment of many pharmacological activities. (jyoungpharm.org)
Condensation1
  • The title compounds were prepared by condensation of 7-methoxychroman-4-one with suitable aldehydes in appropriate alcohol in the presence of gaseous HCl. (irost.org)
Antifungal activity1
  • antifungal activity of biflavones from taxus baccata and ginkgo biloba. (liverpool.ac.uk)
Biological activities2
  • Benzimidazole analogues are often more powerful, medicinally significant chemicals with a wide range of biological activities. (ijpsr.com)
  • Because of the medications' uses in the treatment of microbe-related infections and other biological activities, stronger and more significant pharmaceuticals are being developed. (ijpsr.com)
Potent2
  • Among the series of compound 9h, 9i, 10h, 10i exhibit more potent against two cancer cell lines MCF7, A549. (jyoungpharm.org)
  • These results suggest that nutmeg seed could serve as the lead compound for potent DHODH inhibitors against skin. (uns.ac.id)
Inhibitors1
  • In the nutshell, this review will drive future research on tankyrase as it enlighten the structural and functional features of TNKS 1 and TNKS 2, different classes of inhibitors with their structure-activity relationship studies, molecular modeling studies, as well as past, current and future perspective of the different class of tankyrase inhibitors. (bvsalud.org)
Antibacterial activity2
  • Our research group has recently developed and synthesized several heterocycle-fused benzimidazoles with outstanding antibacterial activity. (ijpsr.com)
  • The thiazolidine ring has strong antibacterial activity, multi-drug resistance in several bacterial strains, and it shows effective in pharmacological treatment. (jyoungpharm.org)
Methods1
  • Methods for UV filter analysis followed the principles of European standardized methods for pesticide residue analysis (EN 15289). (researchgate.net)
Newly2
  • Structures of the newly synthesized compounds 4a-i and 8a-l have been characterized by 1H NMR, 13C NMR, MS and elemental analysis. (bvsalud.org)
  • To the above product different primary and secondary aromaticamines in presence of DMF were treated to get newly targeted compound throughreplacing at 7th position chlorine. (ignited.in)
Ethanol1
  • All the synthesized compound are purified by using ethanol for recrystallization. (jyoungpharm.org)
Anticancer2
  • Therefore, compound 5b prototype could be considered as novel cytotoxic agent for further developing new anticancer chemotherapeutics. (irost.org)
  • Anticancer activities were evaluated against MCF-7, A549, HepG2 and MCF-10A by MTT based assay. (bvsalud.org)
Readily2
  • the benefit of this present protocol is highlighted by its readily available starting materials, superior functional group tolerance, purity of synthesized compounds was checked by high-performance liquid chromatography results in up to 99.7% purity for the synthesized compounds, reaction mass efficiency, effective mass yield, and excellent atom economy. (bvsalud.org)
  • Multiple sets of information for the compounds with high drug-likeness score are readily accessible. (molinstincts.com)
Cytotoxic3
  • Although the direct analog of SJ-172550 (compound 5d ) did not show any cytotoxic activity against tested cell lines, but 2-(2-chloro-6-methoxyphenoxy)acetic acid methyl ester analog 5c showed some activity against MDA-MB-231 and SK-N-MC cells. (irost.org)
  • Further modification of compound 5c resulted in the 3-chloro-4,5-dimethoxybenzylidene derivative 5b which demonstrated better cytotoxic profile against all tested cell lines (IC 50 values = 7.56-25.04 μg/ml). (irost.org)
  • The results demonstrated that the cytotoxic activity of compound 5b against MDA-MB-231 and SK-N-MC cells is more than etoposide. (irost.org)
Pharmacological1
  • These compounds have been found to be efficient against various bacteria in pharmacological tests. (ijpsr.com)
Found2
  • Compared with the positive control Adriamycin, compounds 4a, 4b, 4c, 4d, 8d, 8e and 8j were found to be most active anti-proliferative compounds against human cancer cell line. (bvsalud.org)
  • We found that compounds 4a and 4c exhibited inhibition of enzyme topoisomerase II with IC50 values 10.28 and 12.38 µM, respectively. (bvsalud.org)
MASS1
  • Gas Chromatography-Mass Spectrometry (CG - MS) was used to identify the compounds of Sapindusrarak DC. (rjptonline.org)
Assay1
  • The antiproliferative activity of target compounds were evaluated against MDA-MB-231 (breast cancer), KB (nasopharyngeal epidermoid carcinoma) and SK-N-MC (human neuroblastoma) cell lines using MTT assay. (irost.org)
Strains1
  • All the compounds exhibited broad-spectrum activity against the tested fungal strains with excellent minimum inhibitory concentration values. (bvsalud.org)
Study3
  • The molecular docking study against sterol 14α-demethylase (CYP51) could provide valuable insights into the binding modes and affinity of these compounds. (bvsalud.org)
  • In silico docking study of synthesized compounds showed that compounds 4a and 4c have good binding affinity toward topoisomerase IIα enzyme and have placed in between DNA base pair at active site of enzyme. (bvsalud.org)
  • This study aimed to determine the antibacterial compound of Sapindusrarak DC (S. rarak DC). (rjptonline.org)
Exhibit1
Effective2
  • It was assumed that for a compound to be effective as a capillary stabilizer, it was necessary for the flavonols or flavones to possess vicinal hydroxyls in the 3′- and 4′-positions, and a hydroxyl at 3-and a carbonyl at 4-position, since the methylation or acetylation of this hydroxyl decreases or obliterates this efficacy. (go.jp)
  • Under white light illumination, the effective electric conductivity for the compound I-8 is five times that obtained in dark conditions. (dntb.gov.ua)
Materials1
  • UV filters are compounds, mixtures, or materials that block or absorb ultraviolet (UV) light. (wikipedia.org)
Title1
  • The title compound contains five-coordinate Zn II ions inter-mediate between square-pyramidal and trigonal-bipyramidal coordination geometries. (iucr.org)
Serve1
  • Aside from the sugars and starches that meet this vital nutritional role, carbohydrates also serve as a structural material (cellulose), a component of the energy transport compound ATP, recognition sites on cell surfaces, and one of three essential components of DNA and RNA. (feinni.best)
High1
  • The anionic hydride HFe 3 (CO) 11 − species grafted in the zeolite by ionic interaction with an Al 3+ ion showed high catalytic activity for the water gas shift reaction, which was comparable to that of iron carbonyl in homogeneous phase. (go.jp)
Positive1
  • Through interpolation of LLNA dose- response data, the concentration of a chemical required to produce a threshold positive response (a 3-fold increase in activity compared with concurrent vehicle controls, the EC3 value) can be measured. (cdc.gov)
Water1
  • Nonetheless, it was evaluated that, during in-water activities, at least 25% of sunscreens and PCPs applied to the skin get washed off [ 11 ] . (encyclopedia.pub)
Treatment1
  • This finding indicates that Sapindusrarak DC has the compound antibacterial to prevent F. nucleatumgrowth, of could be a recommendation as an alternative to natural root canal irrigation in the field of endodontic treatment. (rjptonline.org)