Activity in tissue. Medical search. Frequent questions

The use of PGE(2) receptor antagonists implicated EP(4) as a main PGE(2) receptor, and injection of the stable PGE(2) analog (EP(3/4) agonist) 16,16 dm PGE(2) induced UCP1 expression in inguinal white adipose tissue. (ku.dk)
Inhibition of COX activity attenuated diet-induced UCP1 expression and increased energy efficiency and adipose tissue mass in obesity-resistant mice kept at thermoneutrality. (ku.dk)
CONCLUSIONS/SIGNIFICANCE: Our findings provide evidence that induction of UCP1 expression in white adipose tissue, but not in classic interscapular brown adipose tissue is dependent on cyclooxygenase activity. (ku.dk)
Our results indicate that cyclooxygenase-dependent induction of UCP1 expression in white adipose tissues is important for diet-induced thermogenesis providing support for a surprising role of COX activity in the control of energy balance and obesity development. (ku.dk)
Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
Adipose tissue-derived mesenchymal stem cells (AD-MSC) show great potential to treat inflammatory and degradative processes in OA and have demonstrated paracrine effects in chondrocytes. (karger.com)
AD-MSC were isolated by collagenase treatment from adipose tissue from healthy individuals subjected to abdominal lipectomy surgery. (karger.com)
In humans the generation of fat cells (adipocytes) is a major factor behind the growth of adipose tissue during childhood. (europa.eu)
One tissue of great interest and significant clinical relevance is adipose tissue. (europa.eu)
Excess adipose tissue, resulting in obesity, is currently one of the most serious threats to human health on a global level. (europa.eu)
The current proposal aims to determine the dynamics of human adipose tissue maintenance and investigate any differences in regulation of the fat mass in lean and obese individuals. (europa.eu)
Report of Health Care Review Article Volume 5 , Issue 1 , 2019 , p. 54 - 62 The Effect of Physical Activity on Adipose Tissue and Skeletal Muscles: A Literature Review Keyvan Hejazi 1* , Seyyed Reza Attarzadeh Hosseini 2 , Meh rdad Fathi 2 , Mohammad Mosaferi Ziaaldini 2 1. (ac.ir)
Therefore, the recognition of molecular cellular mechanisms caused by the response to sport training, especially weight training exercises and changes in white and brown adipose tissue, is one of the most important parts of the thermogenesis regulation, which requires more studies. (ac.ir)
One of the characteristics of exercise effects is the conversion of white adipose tissue i nto brown adipose tissue. (ac.ir)
The purpose of this study was to investigate the e ffect of physical activity on adipose tissue and skeletal muscles. (ac.ir)
Results: Based on our literature review, physical exercise can be effective as an adipose tissue activated agent in the prevention and treatment of obesity. (ac.ir)
In this regard, irisin seems to be influenced by a vari ety of sports activities and is a significant factor in the conversion of white to brown adipose tissues and can play a role in weight loss and increase the body thermogenesis. (ac.ir)
Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity. (ox.ac.uk)
Genome-wide association studies of δ-5-desaturase (D5D), δ-6-desaturase (D6D) and stearoyl-CoA desaturase-1 (SCD) activities (estimated by product-to-precursor ratios of fatty acids analyzed by gas chromatography) in serum cholesterol esters (n = 1453) and adipose tissue (n = 783, all men) were performed in two Swedish population-based cohorts. (ox.ac.uk)
Variants at the FADS1 were strongly associated with D5D in both cholesterol esters (p = 1.9 × 10-70) and adipose tissue (p = 1.1 × 10-27). (ox.ac.uk)
and near MC4R, p = 3.7 × 10-8) but no associations with D6D in adipose tissue attained genome-wide significance. (ox.ac.uk)
One locus was associated with SCD in adipose tissue (PKDL1, p = 2.2 × 10-19). (ox.ac.uk)
However, fatty acid (FA) ratios in adipose tissue and cholesterol esters represent FADS activities in separate tissues and are thus influenced by different genetic factors with potential varying effects on IS. (ox.ac.uk)
Besides, a role could be ascribed to molecules secreted by the visceral adipose tissue that can impact on barrier functions. (hindawi.com)
Brown adipose tissue has played a key role in prevention research since its presence was first documented in adults. (esanum.com)
A team at the Technical University Munich (TUM) and the Helmholtz Zentrum München has now succeeded in making the activity of brown adipose tissue visible without injecting substances. (esanum.com)
In the cold, brown adipose tissue acts like a heat generator, and its activity has a positive effect on the energy balance. (esanum.com)
The heat output of brown adipose tissue in humans decreases with increasing age. (esanum.com)
Therefore, scientists are researching the factors which keep the brown adipose tissue active. (esanum.com)
Until now, it has only been possible to measure the heat output of brown adipose tissue by means of invasive methods. (esanum.com)
The study demonstrated a direct relationship between the metabolic activation of the brown adipose tissue measured using hemoglobin gradients as an intrinsic biomarker of tissue metabolism and its calorie consumption after stimulation. (esanum.com)
The higher metabolic demand of the brown adipose tissue is supplied by increased blood circulation and oxygen utilization, which can be made visible in the tissue and the venous outflow by MSOT" explains Professor Martin Klingenspor from the Chair for Molecular Nutritional Medicine, one of the main authors of the study which was published in " Cell Metabolism . (esanum.com)
Adipose tissue (also known as body fat, or simply fat) is a loose connective tissue composed mostly of adipocytes. (wikipedia.org)
In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages. (wikipedia.org)
Adipose tissue is derived from preadipocytes. (wikipedia.org)
Far from being hormonally inert, adipose tissue has, in recent years, been recognized as a major endocrine organ, as it produces hormones such as leptin, estrogen, resistin, and cytokines (especially TNFα). (wikipedia.org)
In obesity, adipose tissue is also implicated in the chronic release of pro-inflammatory markers known as adipokines, which are responsible for the development of metabolic syndrome, a constellation of diseases, including type 2 diabetes, cardiovascular disease and atherosclerosis. (wikipedia.org)
The two types of adipose tissue are white adipose tissue (WAT), which stores energy, and brown adipose tissue (BAT), which generates body heat. (wikipedia.org)
The formation of adipose tissue appears to be controlled in part by the adipose gene. (wikipedia.org)
Adipose tissue - more specifically brown adipose tissue - was first identified by the Swiss naturalist Conrad Gessner in 1551. (wikipedia.org)
In humans, adipose tissue is located: beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow), intermuscular (Muscular system) and in the breast (breast tissue). (wikipedia.org)
Adipose tissue is found in specific locations, which are referred to as adipose depots. (wikipedia.org)
Apart from adipocytes, which comprise the highest percentage of cells within adipose tissue, other cell types are present, collectively termed stromal vascular fraction (SVF) of cells. (wikipedia.org)
Adipose tissue contains many small blood vessels. (wikipedia.org)
However, its main function is to be a reserve of lipids, which can be oxidised to meet the energy needs of the body and to protect it from excess glucose by storing triglycerides produced by the liver from sugars, although some evidence suggests that most lipid synthesis from carbohydrates occurs in the adipose tissue itself. (wikipedia.org)
The two superficial depots are the paired inguinal depots, which are found anterior to the upper segment of the hind limbs (underneath the skin) and the subscapular depots, paired medial mixtures of brown adipose tissue adjacent to regions of white adipose tissue, which are found under the skin between the dorsal crests of the scapulae. (wikipedia.org)
In an obese person, excess adipose tissue hanging downward from the abdomen is referred to as a panniculus. (wikipedia.org)
Adipose tissue plays an important role in metabolism through its storage and release of triglycerides, peptide hormones (adipokines) and other proteins, and in the case of brown fat, for its role in thermogenesis ( 1 ). (diabetesjournals.org)
Lipodystrophy, lack of adipose tissue, is also associated with insulin resistance. (cambridge.org)
Any plausible explanation for the link between excess adipose tissue and insulin resistance needs to be able to account for this observation. (cambridge.org)
Adipose tissue in obesity becomes refractory to suppression of fat mobilization by insulin, and also to the normal acute stimulatory effect of insulin on activation of lipoprotein lipase (involved in fat storage). (cambridge.org)
Thus, in the postprandial period especially, there is an excess flux of circulating lipid metabolites that would normally have been 'absorbed' by adipose tissue. (cambridge.org)
In lipodystrophy there is insufficient adipose tissue to absorb the postprandial influx of fatty acids, so these fatty acids will again be directed to other tissues. (cambridge.org)
This view of the link between adipose tissue and insulin resistance emphasises the important role of adipose tissue in 'buffering' the daily influx of dietary fat entering the circulation and preventing excessive exposure of other tissues to this influx. (cambridge.org)
Adipose tissue (AT) represents a commonly used source of mesenchymal stem/stromal cells (MSCs) whose proregenerative potential has been widely investigated in multiple clinical trials worldwide. (mdpi.com)
Adipose tissue is abundant in the breast. (lu.se)
In this review, we address the current knowledge on the changes in the breast adipose tissue in obesity associated with breast cancer initiation and progression. (lu.se)
Studies investigating mammary adipocytes and breast adipose tissue in women with obesity versus women without obesity are, however, sparse and further research is needed. (lu.se)

Separate groups of rats underwent in vivo single-fiber recording 1 day after a sham procedure, skin, or skin plus deep tissue incision or 7 days after skin plus deep tissue incision. (nih.gov)
Here, combining the biochemical analysis of enzymatic and motile properties for purified myosin mutants with in vivo measurements of apical constriction for the same mutants, we show that in vivo constriction rate scales with myosin motor activity. (elifesciences.org)
The team indicate in future it could be possible to graft protocellular materials onto organs to provide targeted therapies, or to use these artificial tissues as organoids to closely replicate in vivo environments for drug screenings and reducing animal testing. (ddw-online.com)
As well as inhibiting bone remodelling, this effect may involve stimulation of osteoblast activity, in light of evidence from recent in vivo studies. (bath.ac.uk)
In Particular, ERGR-mediated GRE-luc activity provides a high signal response to estrogen agonists and SERMs, in a cell context dependent manner closely resembling that observed in vivo. (bath.ac.uk)
Histological, RT-qPCR, western blot analyses and steroid hormone measurements were performed on in vitro cultured mouse prepubertal testicular tissues and age-matched in vivo controls. (elifesciences.org)
Several fertility restoration approaches, whose aim is to mature cryopreserved tissues in vivo or in vitro in order to produce spermatozoa, are being developed. (elifesciences.org)
Together, our in vivo and in silico data provide a framework for understanding how cells orient force generation, establishing a role for geometrical and mechanical patterning of force production in tissues. (nature.com)
Conditional gene targeting has been extensively used for in vivo analysis of gene function in adipocyte cell biology but often with debate over the tissue specificity and the efficacy of inactivation. (diabetesjournals.org)
One of the potential limitations associated with the use of alginate for in vivo tissue regeneration is that it is in general non-degradable by mammals, as they lack the enzymes needed to break down the polymer chains 21 . (nature.com)
Relating in vitro to in vivo exposures with physiologically based tissue dosimetry and tissue response models. (cdc.gov)

Our next goal is to advance the biochemical capabilities and levels of autonomy of our protocellular materials to target important applications in tissue engineering, personalised therapy, pharmacokinetics, micro-bioreactor technologies, and soft robotics. (ddw-online.com)
Previous work has shown that gradients or asymmetries in biochemical signals at the cell and tissue level can serve as instructive cues to pattern force generation. (nature.com)
Specifically, these materials recapitulate the biochemical cues, physicochemical stimuli, and native architecture found in these tissues. (leica-microsystems.com)
In addition, chronic diagnostic test for follow-up of patients cy and for biochemical determination inflammation associated with the infec- with H. pylori gastritis and were able of tissue COX-2 activity using COX tion leads to damage in proteins, the to predict the risk of development of Activity Assay Kit (Cayman Chemical production of reactive oxygen species stomach cancer. (who.int)

Rockwell Automation's efforts to integrate biomanufacturing science with production techniques are helping to transform regenerative medicine, using smart automation to help to mass produce safe and reliable biological products such as human tissues, skin, cartilage, and replacement organs. (rockwellautomation.com)
Discuss the importance of mimicking structures of tissues and organs. (manchester.ac.uk)
Tissue engineering (TE) is a promising strategy for replacing, repairing or regenerating damaged tissues and organs. (nature.com)

Scientists have created new artificial tissues that mimic some of the complex characteristics and abilities of living tissues, paving the way towards unprecedented advances in medicine, soft-robotics, and micro-engineering. (ddw-online.com)
Tissue engineering develops materials that mimic biological tissues [1] . (leica-microsystems.com)

[ 3 ] Time wasted attempting to arrange for imaging studies, laboratory testing, or other diagnostic procedures results in the loss of testicular tissue. (medscape.com)
A complete in vitro spermatogenesis has been obtained from mouse prepubertal testicular tissue, although with low efficiency. (elifesciences.org)
This study reports useful information on the limits of the organotypic culture of neonatal mouse testes, which has been regarded as an experimental strategy that can be extended to humans in the clinical setting for the conservation and subsequent re-use of testicular tissue. (elifesciences.org)
Freezing of prepubertal testicular tissue containing spermatogonia is a fertility preservation option proposed to prepubertal boys with cancer prior to highly gonadotoxic treatments. (elifesciences.org)
In vitro spermatogenesis could indeed be proposed to patients with testicular localization of residual tumor cells, for whom testicular tissue autografting is not indicated (about 30% of patients with acute leukemia). (elifesciences.org)
The organotypic culture procedure, which preserves testicular tissue architecture, microenvironment and cell interactions, has been used successfully to obtain spermatozoa from fresh or frozen/thawed mouse prepubertal testicular tissues ( 3 - 6 ). (elifesciences.org)
It has been previously shown that supplementing organotypic culture media with retinol improves the in vitro production of spermatids and spermatozoa in prepubertal mouse testicular tissues cultured at a gas-liquid interphase ( 5 , 7 ). (elifesciences.org)

Tissue engineers use biomaterials for a variety of applications from drug delivery to supporting the regeneration of damaged or lost tissues to creating in vitro disease models. (leica-microsystems.com)
Mollie Smoak's research focuses on the synthesis, processing, and evaluation of new biomaterials for use as scaffolds to support the regeneration of musculoskeletal tissues [2] . (leica-microsystems.com)
Develop an understanding of the principles of tissue engineering, the biomaterials commonly used and discuss some specific examples of engineered tissues. (manchester.ac.uk)
TE strategies typically incorporate cells, biomaterials and signals (e.g. growth factors), with the goal of developing a construct that once implanted will promote tissue regeneration. (nature.com)

This summary, on eye and tissue donation activity, presents a series of graphs and tables reported by contributing banks across Australia to the Organ and Tissue Authority (OTA) national data collection program. (anzdata.org.au)
http://www.researchandmarkets.com/research/f7thqr/organ_and_tissue ) has announced the addition of the "Organ and Tissue Transplantation - Global Strategic Business Report" report to their offering. (prnewswire.com)
This report analyzes the worldwide markets for Organ and Tissue Transplantation in Number of Procedures. (prnewswire.com)
The global and regional markets (except the US) for 'Organ and Tissue Transplantation' in this report are analyzed by the following Product Segments - Organ Tranplantation (Heart, Kidneys, Liver, Pancreas, and Lungs). (prnewswire.com)
Be able to give specific tissue and organ examples. (manchester.ac.uk)
Limitations should occur only secondary to serious organ involvement that prevents performance of activities. (medscape.com)

West Nile Virus transmission through tissue transplantation, for instance, skin, muscle, or connective tissues, has not been identified, and the risk for transmission by this route is not known. (cdc.gov)

This situation leads to fat deposition in other tissues. (cambridge.org)

METHODOLOGY/PRINCIPAL FINDINGS: Here we report that cyclooxygenase (COX) activity and prostaglandin E(2) (PGE(2)) are crucially involved in induction of UCP1 expression in inguinal white adipocytes, but not in classic interscapular brown adipocytes. (ku.dk)
The present article discusses how accumulation of triacylglycerol in adipocytes can lead to deterioration of the responsiveness of glucose metabolism in other tissues. (cambridge.org)

Professor Vasilis Ntziachristos, Director of the Chair for Biological Imaging at TUM and the Institute of Biological and Medical Imaging at Helmholtz Zentrum München has pioneered MSOT explains the new investigative method as follows: "A laser beam sends light pulses approximately two to three centimeters deep into the tissue. (esanum.com)
It is important to recognize that because of the biological activity of these contaminants, dose-response relationships obtained using technical grade methoxychlor may not be directly applicable to pure methoxychlor. (cdc.gov)

The National Institutes of Health (NIH) intends to support the development of innovative methods for quantitative evaluation of myofascial tissues for pain management involving research participants using a two-phase grant funding mechanism. (nih.gov)
https://heal.nih.gov/ This notice of funding opportunity (NOFO) seeks research applications to develop quantitative measures of myofascial tissues and assess their abilities to detect changes to myofascial tissues across a variety of pain management interventions. (nih.gov)
The first phase, funded by the R61, will provide funding for up to 3 years to develop quantitative measures that can differentiate abnormal myofascial tissue from healthy tissues using cross-sectional correlations with clinical signs/symptoms. (nih.gov)
A collection of explicit strategies like myofascial conveyance and Rolfing of the deep tissue massage are as of now being told at various specific schools and this is one more proof of the unbounded achievement of the trademark difficulty treatment. (larteppes.org)

Bronchoalveolar lavage (BAL) toxicity parameters such as lactate dehydrogenase activity, number of AMs and PMNs, oxidant production by phagocytes, and levels of multiple cytokines (IL-1beta, IL-10, MCP-1, MIP-2, and TNF-alpha) were significantly altered in response to inhalation exposure to MWCNT in the rats. (cdc.gov)

Not the least bit like various massages which offer an overall easing and excess, the deep tissue massage techniques offers disorder for unequivocal unbearable regions and illnesses like Osteoarthritis and carpal section condition. (larteppes.org)

Macrophages are versatile cells that can be polarized by the tissue environment to fulfill required needs. (haematologica.org)
In addition, also TF activity was enhanced in extracellular vesicles of alternatively polarized macrophages. (haematologica.org)
In contrast to monocytes, human macrophages did not show increased tissue factor expression upon stimulation with lipopolysaccharide and interferon-γ. (haematologica.org)
Macrophages reside in all tissues of the body and each population of macrophages within a tissue can take on specialized functions that are tuned to the developmental and functional requirements of that tissue. (haematologica.org)
1 Some tissue macrophages and precursors are already established embryonically in the yolk sac and fetal liver before the onset of definitive hematopoiesis. (haematologica.org)
6 In addition, these cells are present during early wound healing and proinflammatory macrophages are characterized by a pronounced ability to degrade tissue. (haematologica.org)
Besides scavenging debris, promoting angiogenesis, tissue remodeling and repair, alternatively activated macrophages are able to fine tune inflammatory responses. (haematologica.org)

You can either have your child cut or rip the tissue paper into small pieces or use pre-cut tissue paper squares for ease. (darcyandbrian.com)
The last step is to attach blue tissue paper squares for the sky. (kidsactivitiesblog.com)

We conclude that evaluation of global estrogenic activity, as opposed to activation of a specific target gene, provides a more accurate read-out for osteoblast stimulation. (bath.ac.uk)
This is because several of the contaminants in technical grade methoxychlor are directly estrogenic (Kupfer and Bulger 1987b), whereas pure methoxychlor is proestrogenic and requires metabolic activation before exhibiting estrogenic activity (Bulger et al. (cdc.gov)

If your child will be cutting the tissue paper themselves, they'll need a pair of scissors. (darcyandbrian.com)

We localized SARS-CoV-2 RNA in neonatal heart and liver vascular endothelium by using in situ hybridization and detected SARS-CoV-2 RNA in neonatal and placental tissues by using reverse transcription PCR. (cdc.gov)

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More detailed spatial and temporal correlations between altered mRNA levels and tissue plasticity may further delineate the molecules responsible for the control of bone mass and morphology. (elsevierpure.com)

SERMs act as ER agonists in bone despite their antagonistic properties in other tissues. (bath.ac.uk)
These data confirm the complexity of the bone remodeling process, both in terms of the number of genes involved, their interaction and coordination of resorptive and formative activity, and the temporal sensitivity of the processes. (elsevierpure.com)
Eight weeks after the donor's death, skin samples that had been treated in cryopreservative solution containing an antibiotic and unprocessed fat, muscle, tendon, and bone samples, all of which had been stored frozen at -70° Celsius at a tissue bank, were transferred to CDC. (cdc.gov)

To address this challenge, we developed the Swarm TM , a custom designed optical instrument for highly parallelized, multicolor measurements in excitable cells, simultaneously recording changes in voltage and calcium activities at high temporal resolution under optical stimulation. (frontiersin.org)

Proinflammatory polarization is associated with increased tissue degradation and propagation of inflammation whereas alternative polarization within a Th2 cytokine environment is associated with wound healing and angiogenesis. (haematologica.org)
MSOT can overall enable the investigation of an increased number of functional tissue parameters, beyond metabolism, including inflammation or angiogenesis. (esanum.com)

To adhere the tissue paper pieces onto the template, you can use either a glue stick or liquid school glue . (darcyandbrian.com)

Although, the non-muscle myosin II holoenzyme (myosin) is a molecular motor that powers contraction of actin cytoskeleton networks, recent studies have questioned the importance of myosin motor activity cell and tissue shape changes. (elifesciences.org)
Overall, our data highlights that myosin activity is required for rapid cell contraction and tissue folding in developing Drosophila embryos. (elifesciences.org)
Forces that shape cells and tissues can be produced by the contraction of actin filament (F-actin) meshworks by the molecular motor Myosin II (myosin). (nature.com)

The methodology of the deep tissue massage treatment is essentially equivalent to those of the Swedish massage yet they contrast on unambiguous grounds. (larteppes.org)

The team of researchers demonstrated a relationship between the metabolic activation of the tissue and changes in oxygenated and deoxygenated hemoglobin (red blood pigment), measured by means of multispectral optoacoustic tomography (MSOT). (esanum.com)

2002. Physiologically based pharmacokinetic (PBPK) models for nasal tissue dosimetry of organic esters: Assessing the state-of-knowledge and risk assessment applications with methyl methacrylate and vinyl acetate. (cdc.gov)

In this case-based discussion, learn about the differences in treatment recommendations for purulent and nonpurulent skin and soft tissue infections, limitations with current treatments, and patient factors that may warrant use of long-acting lipoglycopeptides as a potential therapy option. (clinicaloptions.com)
Eribulin activity in soft tissue sarcoma monolayer and three-dimensional cell line models: could the combination with other drugs improve its antitumoral effect? (helsinki.fi)

Rat pain behaviors were measured after a sham procedure, skin incision, or skin plus deep tissue incision. (nih.gov)
Mechanical and heat hyperalgesia were similar in both incised groups, except that mechanical hyperalgesia lasted longer after skin plus deep tissue incision. (nih.gov)
SA rate also tended to be greater (6.1 vs. 10.0 imp/s) after skin plus deep tissue incision. (nih.gov)
Seven days after skin plus deep tissue incision, the SA prevalence was similar (13.6%) as in controls. (nih.gov)
These data demonstrated that incised deep tissue rather than skin had a central role in the genesis of guarding behavior and nociceptor SA. (nih.gov)
Understanding the responses of deep tissue to incision and the mechanisms for deep tissue pain will improve postoperative pain management. (nih.gov)
A deep tissue massage in one in which the deeper solid layers and the burden in the inward tissues due to grasps are caused. (larteppes.org)
When diverged from various kinds of massages, the deep tissue 마사지 massage strategies uses moderate and outrageous improvements along the constrain domains to reach to the inward layers. (larteppes.org)
The expert might use his lower arms, hand joints, fingers or thumbs and deep and extraordinary improvements are applied which will overall cripple the connections and when the deep tissue massage techniques are applied for a broad time period at customary stretches all grasp are broken. (larteppes.org)
Another part which makes the deep tissue massages techniques especially novel comparable to the rest is the use of various instruments that assistance in entrance. (larteppes.org)

Matrix stiffness is a key determinant of mesenchymal stem cell (MSC) differentiation, suggesting that modulation of alginate bioink mechanical properties represents a promising strategy to spatially regulate MSC fate within bioprinted tissues. (nature.com)

Scaffold architecture can be tailored to specific tissue engineering applications. (leica-microsystems.com)

Gather tissue paper, contact paper, an embroidery hoop, and scissors for your poppies craft. (kidsactivitiesblog.com)
Have the child help tear by hand or cut the tissue paper with scissors. (busylittleizzy.com)

There, the tissues remained frozen at -20° Celsius to -70° Celsius in individual double- wrapping and plastic bags and were handled and tested separately to reduce the risk for cross- contamination. (cdc.gov)

The second phase, funded under the R33, will provide support to assess the abilities of the quantitative measures developed in the R61 phase to measure tissue changes in response to therapies or manipulations that may relieve pain using rigorous, longitudinal clinical study design. (nih.gov)

Recently I developed a method that is based on the incorporation of 14C from nuclear bomb tests into genomic DNA, which allows for the analysis of cell and tissue turnover in humans. (europa.eu)

The defect in the myosin motor activity in these mutants is evident in developing Drosophila embryos where tissue recoil following laser ablation is decreased compared to wild-type tissue. (elifesciences.org)
However, it has not been biochemically demonstrated that Drosophila myosin motor activity and filament assembly is regulated by RLC phosphorylation or whether the extent of activation is similar to that of mammalian systems. (elifesciences.org)
In the Drosophila embryo, apical constriction in a strip of epithelial cells along the ventral midline results in the folding of the tissue and the internalization of ventral cells, forming a ventral furrow (VF). (nature.com)
In Drosophila , InsP 3 R activity is required in aminergic interneurons during pupal development for normal flight behavior. (jneurosci.org)

A team, led by Dr Pierangelo Gobbo from the university's School of Chemistry, developed the new technique and used it to assemble millions of sticky synthetic cells, called "protocells", into artificial tissues capable of communicating with each other as well as with their external environment. (ddw-online.com)
SERMs caused a modest increase in ERE-luc activity in osteoblast-like cells (but not in breast cells), and a reduction in nuclear mobility in breast (but not osteoblast-like) cells. (bath.ac.uk)
Interestingly, SERMs increased both cytoplasmic to nuclear translocation of ERGR-GFP, and GRE-luc reporter activity, in osteoblast-like (but not breast) cells. (bath.ac.uk)
Indeed, transcriptional responses to SERMs in osteoblast-like cells were considerably greater with the ERGR/GRE-luc than the ER alpha/ERE-luc system, 4-HT inducing 300 and 25% increases in reporter activity respectively. (bath.ac.uk)
Transcript levels of the androgen receptor (AR)-regulated gene Rhox5 were decreased at the end of the culture period, suggesting that testosterone production by Leydig cells and/or AR transcriptional activity was impaired in organotypic cultures ( 8 ). (elifesciences.org)
Thus, it is critical to understand how cells orient the cytoskeleton to produce forces that deform tissues. (nature.com)
The magnitude, direction and timing of contractile force depend on the organization of the cellular actomyosin meshworks and how these networks are connected between cells at the level of the tissue. (nature.com)
How cells determine the direction in which they apply force is of critical importance to cell and tissue shape changes. (nature.com)
How epithelial cells actively respond to mechanical constraints by adjusting how they generate force is important to understand tissue morphogenesis. (nature.com)

Non-muscle cell contractility is critical for tissues to adopt shape changes. (elifesciences.org)
Cell shape changes and cell movements drive these tissue-scale transformations. (elifesciences.org)
In conclusion, this study reports the failure of adult Leydig cell development and altered steroid production and signaling in tissue cultures. (elifesciences.org)
problems include thymic atrophy and diminished T-cell activity. (medscape.com)

The University of Bristol-led breakthrough, published in Advanced Materials , has reported the first way to produce centimetre-sized artificial tissues of any shape and with complex internal structures. (ddw-online.com)

Work done using smooth muscle myosin and mammalian non-muscle myosin have demonstrated that phosphorylation of the RLC at conserved Serine and Threonine sites ( Figure 1B , Serine-19 and Threonine-18) activates myosin motor activity, enhances the affinity of myosin for actin, and promotes myosin filament assembly ( Heissler and Sellers, 2016 ). (elifesciences.org)

The motor domain catalyzes the hydrolysis of ATP to power the translocation of actin filaments, a function referred to as motor activity. (elifesciences.org)

Little is known about the effect of the commonly used doses of radiation therapy on normal breast tissue. (maastrichtuniversity.nl)

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. (clinicaloptions.com)
We describe the detection and localization of SARS-CoV-2 in autopsy tissues from a 25-week neonate who died at 4 days of age with clinical history, laboratory, and pathologic findings consistent with severe COVID-19. (cdc.gov)
The most important tools in treatment of mixed connective tissue disease (MCTD) include tailoring the medical regimen, promptly attending to disease flare, and performing careful and frequent clinical and laboratory evaluations to test for new disease manifestations. (medscape.com)
Ortega-Hernandez OD, Shoenfeld Y. Mixed connective tissue disease: An overview of clinical manifestations, diagnosis and treatment. (medscape.com)

Dr Pierangelo Gobbo, Vice-Chancellor's Fellow at the University of Bristol and Principal Investigator of the project, added: "The controlled assembly of protocells into centimetre-sized protocellular materials endowed with emerging bio-sensing capabilities is unprecedented and represents an important milestone towards the construction of fully autonomous and adaptive artificial tissues. (ddw-online.com)
Whether this responsiveness to external force and geometry is important to orient force generation during the development of a tissue is poorly understood. (nature.com)

Using a combination of genetic and mechanical perturbations that alter tissue shape, we demonstrate that geometrical and mechanical constraints act as cues to orient the cytoskeleton and tension during ventral furrow formation. (nature.com)

Under normal conditions, the dynamic balance of T helper type 1 (Th1) and Th2 activities maintains the immune homeostasis of the body. (hindawi.com)

Spontaneous activity (SA) in nociceptive pathways quite likely transmits such ongoing pain. (nih.gov)
Neuronal control of behavior arises from the activity of underlying neural circuits, which in turn are specified by the interaction of various signaling pathways. (jneurosci.org)

He was cared for at home and had outdoor exposure in a county with known West Nile Virus activity. (cdc.gov)

Corneas, heart valves, and vascular tissue were not procured. (cdc.gov)

have as include your download neuronal activity in value of communicators to leave up with 19-year-old home to be an obscure box of andhuman. (thefentongroup.net)
14 and later has an download neuronal activity in of a up friendly wife for reading the worthy characters of a algorithm of finite customer. (thefentongroup.net)

Widefield microscopy can reach its limits when used for tissue engineering due to the thickness and optical characteristics of the tissue. (leica-microsystems.com)

The goal of this activity is to improve learners' knowledge and competence in management of ABSSSIs, including appropriate utilization of LALs. (clinicaloptions.com)
Depression and anxiety and their association with healthcare utilization in pediatric lupus and mixed connective tissue disease patients: a cross-sectional study. (medscape.com)

Adipose58

Vivo11

Biochemical4

Organs3

Mimic2

Testicular7

Biomaterials4

Organ6

Transplantation1

Deposition1

Adipocytes2

Biological2

Myofascial4

Rats1

Excess1

Macrophages7

Paper squares2

Estrogenic activity2

Cutting the tissue paper1

Liver1

Tumor17

Correlations1

Bone3

Stimulation1

Angiogenesis2

Adhere1

Contraction3

METHODOLOGY1

Metabolic activation1

Esters1

Soft tissue2

Deep tissue10

Mesenchymal1

Specific tissue1

Scissors2

Frozen1

Abilities1

Humans1

Drosophila4

Cells9

Cell4

Structures1

Enhances1

Actin1

Commonly1

Clinical4

Important2

Mechanical1

Immune1

Pathways2

Exposure1

Vascular1

Neuronal2

Characteristics1

Utilization2