IsomeraseArabidopsisAldoseCatalyticMetabolismGlucosePolymersPutativeGalactoseEnzymesBreak down carbohydratesFructoseSynthesisFattyGalactosemiaEnzyme activityEscherichiaGlycogenGlycolyticProteinsGALTDerivativesTransferase activityAminoMoleculesCellularRegulationGeneHumansPotatoDisorderPathwaysRecombinantCells
Isomerase3
- The recombinant xylose isomerase showed the highest activity at 85 degrees C with a specific activity of 1.0 U mg-1. (lu.se)
- Molecular function: sulfoquinovose isomerase activity. (expasy.org)
- The 5‐carbon sugar phosphates are interconverted by the action of epimerase and isomerase to yield ribulose‐5‐phosphate, which is phosphorylated by the enzyme ribulose phosphate kinase to make RuBP, the acceptor of CO 2 . (cliffsnotes.com)
Arabidopsis1
- Identification and characterization of a UDP-D-glucuronate 4-epimerase in Arabidopsis. (mpg.de)
Aldose1
- 2] "Carbohydrate utilization in Streptococcus thermophilus: characterization of the genes for aldose 1-epimerase (mutarotase) and UDPglucose 4-epimerase. (tcdb.org)
Catalytic1
- The catalytic activity of the enzyme is destroyed at a high temperature. (priyamstudycentre.com)
Metabolism11
- Inborn errors of carbohydrate metabolism are inborn error of metabolism that affect the catabolism and anabolism of carbohydrates. (wikipedia.org)
- The failure to effectively use these molecules accounts for the majority of the inborn errors of human carbohydrates metabolism. (wikipedia.org)
- Galactosemia, the inability to metabolize galactose in liver cells, is the most common monogenic disorder of carbohydrate metabolism, affecting 1 in every 55,000 newborns. (wikipedia.org)
- Carbohydrate metabolism.nucleotide sugar. (ntu.edu.sg)
- Galactosemia is an inborn disorder of carbohydrate metabolism of which early detection can prevent severe illness. (bvsalud.org)
- The depletion of DOM over time was strongly correlated with increases in expression of many genes associated with heterotrophy (e.g., amino acid, fatty acid, and carbohydrate metabolism) belonging to a Hydrogenophaga strain that accounted for a relatively large percentage (~8%) of the metatranscriptome. (frontiersin.org)
- Hereditary galactosemia is among the most common carbohydrate metabolism disorders and can be a life-threatening illness during the newborn period. (medscape.com)
- Developmental analysis of carbohydrate metabolism in tomato (Lycopersicon esculentum cv. (mpg.de)
- Inhibition of chloroplastic fructose 1,6-bisphosphatase in tomato fruits leads to decreased fruit size, but only small changes in carbohydrate metabolism. (mpg.de)
- IBS further showed transcriptional upregulation of enzymes involved in fructose and glucan metabolism as well as the succinate pathway of carbohydrate fermentation. (biomedcentral.com)
- Obiadalla-Ali, H. , Fernie, A. R. , Kossmann, J. & Lloyd, J. R. Developmental analysis of carbohydrate metabolism in tomato (Lycopersicon esculentum cv. (mpg.de)
Glucose9
- The metabolic pathway glycolysis is used by cells to break down carbohydrates like glucose (and various other simple sugars) in order to extract energy from them. (wikipedia.org)
- Cancer cells also enhance glucose-uptake to fuel these enhanced metabolic activities [ 2 ]. (degruyter.com)
- Consequently, we present here an optimized poly-LacNAc synthesis by the combination of two glycosyltransferases and a uridine-diphospho-glucose/N-acetylglucosamine 4'-epimerase as one-pot strategy resulting in long poly-LacNAc glycans with up to six LacNAc units in high yields while minimizing reaction time and product loss. (uni-koeln.de)
- Uridine diphosphate (UDP) galactose-4-epimerase epimerizes UDP galactose to UDP glucose and is also uncommon. (medscape.com)
- GALM (glactose mutorotase, aldose1-epimerase) catalyzes the interconversion of the alpha and the beta anomers of hexose sugars like glucose and galactose and is not common. (medscape.com)
- The rest of the Calvin cycle is involved in interconversion of carbohydrates to make glucose (or starch) and the regeneration of the ribulose‐bisphosphate acceptor. (cliffsnotes.com)
- Accepted August 23, 2012 ABSTRACT The catabolite control protein CcpA is a pleiotropic regulator that mediates the global transcriptional response to rapidly catabolizable carbohydrates, like glucose in Gram-positive bacteria. (studyres.com)
- Numerous carbohydrates, including glucose, meet their catabolic end in $ycolysis after being transformed into glycolytic intermediates. (microbiologynote.com)
- D-Fructose + D-Glucose Classical Galactosemia on Diet Autosomal Recessive Inheritance Galactosemia Variants Gal-1-P-UDT GalKinase Epimerase 9p13 - p21 17q21-q22 1p32 - pter Duarte Los Angeles Indian Rennes Philadelphia Negro Chicago A 2-day-old female infant is refusing to feed and has become increasingly lethargic and hypotonic over the past 2 hours. (abcdocz.com)
Polymers1
- Xylans are defined as carbohydrate polymers consisting of a β-1,4-xylosyl (Xyl p ) backbone, although xylans containing a β-1,3 and mixed linkage β-1,4-1,3 backbone structure have been found in algal species [ 9 ]. (biomedcentral.com)
Putative1
- Encodes a putative membrane-anchored UDP-D-glucuronate 4-epimerase. (riken.jp)
Galactose4
- A milder form of galactosemia, called Galactokinase deficiency, is caused a lack of the enzyme uridine diphosphate galactose-4-epimerase which breaks down a byproduct of galactose. (wikipedia.org)
- Although the assay for galactose-1-phosphate uridyltransferase (GALT) enzyme activity has been available since the 1960s, many issues prevented it from becoming universal. (bvsalud.org)
- In order to develop the Israeli newborn screening pilot algorithm for galactosemia, flow injection analysis tandem mass spectrometry measurement of galactose-1-phosphate in archived dried blood spots from newborns with classical galactosemia, galactosemia variants, epimerase deficiency, and normal controls, was conducted. (bvsalud.org)
- Following this pilot study, the Israeli final and routine newborn screening algorithm, as recommended by the Advisory Committee to the National Newborn Screening Program, now consists of galactose-1-phosphate measurement integrated into the routine tandem mass spectrometry panel as the first-tier screening test, and GALT enzyme activity as the second-tier performed to identify only newborns suspected to be at risk for classical galactosemia. (bvsalud.org)
Enzymes1
- Usually, enzymes are present in various cells and exhibit their activity when they are extracted from their source. (priyamstudycentre.com)
Break down carbohydrates1
- For example, carbohydrase can break down carbohydrates into sugars, lipase can break down fats into fatty acids and protease breaks down protein into amino acids. (priyamstudycentre.com)
Fructose3
- The disclosure provides a method of producing allulose by contacting a protein having at least 90% sequence identity to the amino acid sequence of SEQ ID NO: 6 with a fructose substrate, wherein the protein has allulose 3-epimerase activity, and at least partially purifying the allulose. (justia.com)
- Downregulation of pyrophosphate: d-fructose-6-phosphate 1-phosphotransferase activity in sugarcane culms enhances sucrose accumulation due to elevated hexose-phosphate levels. (mpg.de)
- van der Merwe, M. J. , Groenewald, J. H. , Stitt, M. , Kossmann, J. & Botha, F. C. Downregulation of pyrophosphate: d-fructose-6-phosphate 1-phosphotransferase activity in sugarcane culms enhances sucrose accumulation due to elevated hexose-phosphate levels. (mpg.de)
Synthesis1
- Conversely, in tissues where the biosynthetic activities, particularly those related to fatty acid and sterol synthesis, are in full swing, the NADPH produced by the PPP is channeled to support these reductive biosynthetic pathways. (microbiologynote.com)
Fatty1
- Of the following, the MOST appropriate laboratory study to obtain is A. B. C. D. E. leukocyte lysosomal enzyme activities plasma long-chain fatty acid levels serum carnitine level urine for reducing substances urine organic acid levels A 3-month-old infant who has a history of gastroesophageal reflux has had increasing vomiting for 2 days. (abcdocz.com)
Galactosemia2
- Out of 431 330 newborns screened during the pilot study (30 months), two with classical galactosemia and four with epimerase deficiency were identified and confirmed. (bvsalud.org)
- African-Americans with galactosemia may have approximately 10% of enzyme activity in the liver but little or no activity in erythrocytes. (medscape.com)
Enzyme activity4
- The GALT enzyme activity cut-off used in the final algorithm was lowered in order to avoid false positives. (bvsalud.org)
- The pH of the solution has a great effect on enzyme activity. (priyamstudycentre.com)
- Affected individuals may have approximately 10% of enzyme activity in the liver but no activity in the erythrocytes. (medscape.com)
- The fusion structure also accelerated the cofactor regeneration rate and maintained the enzyme activity, so the productivity and yield of l -tle by GDH-R3-LeuDH was all enhanced by twofold. (biomedcentral.com)
Escherichia1
- 5'-monophosphate deaminase from Streptomyces murinus, D-allulose 3-epimerase from Arthrobacter globiformis expressed in Escherichia coli , carbohydrate-derived fulvic acid, jagua (genipin-glycine) blue (Jagua blue), lipase from Mucor javanicus and phosphatidylinositol-specific phospholipase C expressed in Pseudomonas fluorescens ). (who.int)
Glycogen1
- in addition glycogen is the storage form of carbohydrates in humans. (wikipedia.org)
Glycolytic1
- Concurrently, the PPP can transmute the carbon skeletons of dietary carbohydrates into intermediates apt for glycolytic and gluconeogenic pathways, thereby enabling the cell to adeptly navigate through the metabolic intricacies and adapt to varying physiological contexts. (microbiologynote.com)
Proteins1
- Proteoglycans are complex macromolecules comprised of a core protein and one or more covalently attached glycosaminoglycans (GAG) chains so that structurally they are both proteins and carbohydrates. (openbiochemistryjournal.com)
GALT1
- [ 17 ] This variant results in increased GALT activity and does not cause hypergalactosemia. (medscape.com)
Derivatives1
- 2014. Structure-activity Studies of (-)-Epigallocatechin Gallate Derivatives as HCV Entry Inhibitors Bioorg. (montclair.edu)
Transferase activity1
- Screening is performed by measuring GAL-1-P urydil transferase activity. (wikipedia.org)
Amino1
- Since the HBP utilizes major macromolecules such as nucleotides, amino acids, carbohydrates, and lipids to produce UDP-GlcNAc, cells may use it as a 'sensor' of energy availability that influences a large number of functional targets that contribute to cancer phenotypes (Fig. 2 ). (biomedcentral.com)
Molecules1
- Chitin is a biological polymer consisting of carbohydrate molecules bonded together to form long chains of polysaccharides. (biomedcentral.com)
Cellular2
- Of note, an increased carbohydrate uptake and/or induction of death receptors of cancer cells was exploited to develop glycoconjugates that potentially induce cellular stress, ROS and apoptosis. (degruyter.com)
- Considering the diversity in cellular requirements and environmental exposures, the PPP meticulously modulates its activity to cater to the divergent metabolic demands of various tissues. (microbiologynote.com)
Regulation1
- Transformed potato plants as a model for studying the hormonal and carbohydrate regulation of tuberization. (mpg.de)
Gene1
- This screen revealed a gene that when silenced increased the activity of platinum-based cytotoxic drugs (e.g. cisplatin, carboplatin, and oxaliplatin) as well as radiation and topoisomerase I inhibitors (e.g. irinotecan and topotecan) but not topoisomerase II inhibitors (e.g. doxorubicin). (oncotarget.com)
Humans1
- For the majority of humans it is the primary carbohydrate source in the diet. (microbiologynote.com)
Potato1
- Introduction of polyphosphate as a novel phosphate pool in the chloroplast of transgenic potato plants modifies carbohydrate partitioning. (mpg.de)
Disorder1
- No improvement Hospitalization at 2 1/2 years for feeding disorder Episodes of weakness, shaking, decreased activity. (abcdocz.com)
Pathways2
- Manipulation of L: -ascorbic acid biosynthesis pathways in Solanum lycopersicum: elevated GDP-mannose pyrophosphorylase activity enhances L: -ascorbate levels in red fruit. (mpg.de)
- IBS is characterized by a multi-omics microbial signature indicating increased capacity to utilize fermentable carbohydrates-consistent with the clinical benefit of diets restricting this energy source-that also includes multiple previously unrecognized metabolites and metabolic pathways. (biomedcentral.com)
Recombinant1
- Activity measurements of the involved recombinant beta 1,4-galactosyltransferase-1 (beta 4GalT-1) and beta 1,3-N-acetylglucosaminyltransferase (beta 3GlcNAcT) with isolated glycan substrates of up to eight sugar units revealed a preference of beta 3GlcNAcT for the tetrasaccharide and no preference of beta 4GalT-1 for a specific glycan length. (uni-koeln.de)
Cells1
- Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase. (uu.se)