Activation is sufficient enzyme activation. Medical search. Frequent questions

3] Platelets localize coagulation to the hemostatic thrombus and protect coagulation enzymes from inhibition by plasma and platelet inhibitors, thus preventing disseminated intravascular coagulation (DIC). (medscape.com)
The activation of PXR was also associated with an inhibition of pro-beta-oxidative genes, such as peroxisome proliferator-activated receptor alpha (PPARalpha) and thiolase, and an up-regulation of PPARgamma, a positive regulator of CD36. (nih.gov)
Its putative mechanism of action involves the inhibition of dihydroorotate dehydrogenase, a key enzyme in the de novo synthesis of deoxyuridine monophosphate (dUMP). (ersjournals.com)
Inhibition of lymphocyte activation and proliferation is therefore an attractive therapeutic strategy. (ersjournals.com)
Inhibition of the PI3K-AKT-mTOR pathway prevented oxidative stress-induced activation of AR signaling. (uky.edu)

Hormones and neurotransmitters act by releasing the inhibitory constraints imposed by the receptors, thus allowing the GTP-regulatory proteins to interact with and control the activity of enzymes such as adenylate cyclase. (nih.gov)
Gray's thesis focused on annotating the distinct roles played by specific caspases-a family of protease enzymes (enzymes that cleave proteins and enzymes) vital to the normal cellular self-demolition known as apoptosis, which fails to occur in cancers or occurs too much in inflammation and neurodegenerative diseases. (ucsf.edu)
The VKORC1 enzyme helps turn on (activate) clotting proteins in the pathway that forms blood clots . (medlineplus.gov)
Warfarin prevents (inhibits) the action of the VKORC1 enzyme and slows the activation of clotting proteins and clot formation. (medlineplus.gov)
Certain VKORC1 gene polymorphisms decrease the amount of functional VKORC1 enzyme available to help activate clotting proteins. (medlineplus.gov)
Oxidation begins with phospholipids and is catalyzed by heme proteins, such as hemoglobin and myoglobin, cytochromes, free iron, enzymes, and sodium chloride. (scielo.br)

Given that treatment for CLN7 disease is likely to be more challenging than for NCLs encoding lysosomal enzymes such as ceroid lipofuscinosis, neuronal 2 (CLN2)/tripeptidyl peptidase 1 (TPP1) 11 here we aimed to understand the biochemical processes affected in CLN7 disease. (nature.com)
The abnormal ion flow results in the activation of biochemical processes (pathways) that lead to increased aldosterone production, causing the hypertension associated with familial hyperaldosteronism type III. (medlineplus.gov)
Magnesium is essential for the formation of bones and teeth, for muscle contraction, for the transmission of nerve impulses, and for the activation of many enzymes (substances that promote biochemical reactions in the body). (ndcn.net)

Under conditions of extreme low-nitrogen stress in the model diazotroph Klebsiella oxytoca, we found remarkably high heterogeneity of nifHDK gene expression, which codes for the structural genes of nitrogenase, one key enzyme of the global nitrogen cycle. (imperial.ac.uk)
Mutations in genes encoding the enzymes that build the GPI anchors are causative, with somatic mutations in the PIG-A gene occurring most frequently. (bvsalud.org)
These genes provide instructions for making two enzymes that are found in the adrenal glands. (medlineplus.gov)
This strategy would also enable expression of genes with selected PfEMP1 adhesion domains, impartial of gene activation mechanisms, via a second round of integrase-mediated recombination. (ecplf2017.org)

An initial denaturation of 30 seconds at 95°C is sufficient for most amplicons from pure DNA templates. (neb.com)
According to our knowledge, we know that a large change in pH will cause instability in the protein structure thus resulting in denaturation of the enzyme. (ipl.org)

Magnesium is an essential macronutrient required for photosynthesis, enzyme activation, and overall plant health. (nuleaffarms.ca)
Potassium is important in a variety of physiological processes, including photosynthesis, carbohydrate and protein metabolism, enzyme activation, and regulation of stomatal and water movement. (zaraee.pk)

We also offer solutions for automation, site-directed mutagenesis, as well as your favorite restriction enzyme, ligase or competent cell products. (neb.com)
however, the RtcR CARF domain controls expression of two conserved RNA repair enzymes, cyclase RtcA and ligase RtcB. (imperial.ac.uk)

The water-soluble fraction of UPs was sufficient for inducing ERK1/2 and p38 phosphorylation, which was also losartan inhibitable. (nih.gov)
Many eukaryotic protein kinases are activated by phosphorylation on a specific conserved residue in the regulatory activation loop, a post-translational modification thought to stabilize the active DFG-In state of the catalytic domain. (elifesciences.org)
Here we use a battery of spectroscopic methods that track different catalytic elements of the kinase domain to show that the ~100 fold activation of the mitotic kinase Aurora A (AurA) by phosphorylation occurs without a population shift from the DFG-Out to the DFG-In state, and that the activation loop of the activated kinase remains highly dynamic. (elifesciences.org)
Instead, molecular dynamics simulations and electron paramagnetic resonance experiments show that phosphorylation triggers a switch within the DFG-In subpopulation from an autoinhibited DFG-In substate to an active DFG-In substate, leading to catalytic activation. (elifesciences.org)
The enzymes that catalyze this process, called protein kinases, are themselves controlled by the phosphorylation of a flexible region called the activation loop. (elifesciences.org)
For many years it had been thought that the purpose of activation loop phosphorylation was to clamp the otherwise flexible activation loop in an active state that allows molecules that need to be phosphorylated to bind to the kinase. (elifesciences.org)
The present study reveals that Ser-744/Ser-748 phosphorylation is required for PKD1 activation in lymphocytes. (figshare.com)

In vivo genetic approach reveals elevated mitochondrial reactive oxygen species (mROS) in Cln7 ∆ex2 neurons that mediates glycolytic enzyme PFKFB3 activation and contributes to CLN7 pathogenesis. (nature.com)
Thus, aberrant upregulation of the glycolytic enzyme PFKFB3 in neurons may contribute to CLN7 pathogenesis and targeting PFKFB3 could alleviate this and other lysosomal storage diseases. (nature.com)
Here, using the Cln7 ∆ex2 mouse model of CLN7 disease, we found an aberrant upregulation of pro-glycolytic enzyme PFKFB3 in neurons that may contribute to CLN7 pathogenesis. (nature.com)
Nasal sustentacular epithelial cells adjacent to olfactory neurons have high angiotensin-converting enzyme 2 receptor levels and are a key site of virus replication. (cdc.gov)

and cytoplasmic tail, encodes sufficient information for RBC surface display. (ecplf2017.org)
In Vitro Toxicity Studies: Cell membrane integrity: Cytoplasmic enzymes leakage (lactate dehydrogenase, ATP enzymes etc. (cdc.gov)

This PXR-mediated lipid accumulation was independent of the activation of the lipogenic transcriptional factor SREBP-1c (sterol regulatory element-binding protein 1c) and its primary lipogenic target enzymes, including fatty-acid synthase (FAS) and acetyl-CoA carboxylase 1 (ACC-1). (nih.gov)
Instead, the lipid accumulation in transgenic mice was associated with an increased expression of the free fatty acid transporter CD36 and several accessory lipogenic enzymes, such as stearoyl-CoA desaturase-1 (SCD-1) and long chain free fatty acid elongase. (nih.gov)
Structured within the lipid framework of the cell membrane, the enzyme system is composed of at least three classes of components (Fig. 1). (nih.gov)
Prostate cancer is thought to be driven by oxidative stress, lipid metabolism, androgen receptor (AR) signaling, and activation of the PI3K-AKT-mTOR pathway, but it is uncertain how they may become coordinated during progression to castration-resistant disease that remains incurable. (uky.edu)
Given that activation of AR signaling and the PI3K-AKT-mTOR pathway is sufficient to elevate SREBP-dependent expression of key lipid biosynthesis enzymes in castration-resistant prostate cancer (CRPC), our findings argued that Plk1 activation was responsible for coordinating and driving these processes to promote and sustain the development of this advanced stage of disease. (uky.edu)

Crystalline silica also was reported to cause adverse renal effects in test animals and to inhibit some enzymes (e.g., cathepsin B) while inducing others (CYP1A1). (nih.gov)
Individuals develop warfarin sensitivity because a lower warfarin dose is needed to inhibit the VKORC1 enzyme, as there is less functional enzyme that needs to be suppressed. (medlineplus.gov)

T cells bearing the γδ receptor type Vγ2Vδ2 are sufficient to control infections with certain gram-negative or gram-positive bacteria in mice that otherwise lack B or T cells. (jci.org)
Transcription of DDR2, a receptor tyrosine kinase that signals in response to triple helical collagen in the surroundings, is induced early during the activation of hepatic stellate cells. (jci.org)
However, PKD-S744E/S748E is not constitutively active but, like the wild type enzyme, requires antigen receptor triggering or phorbol ester stimulation. (figshare.com)
Antigen receptor activation of wild type PKD is dependent on phospholipase C (PLC)/diacylglycerol (DAG) and PKC, whereas PKD-S744E/S748E is only dependent on PLC/DAG but no longer requires PKC. (figshare.com)
2) Block of cysteinyl leukotriene type I receptors on resting mast cells with the clinically prescribed receptor antagonist montelukast prevented their activation by active mast cells. (ox.ac.uk)

Through catalyzation, the process of speeding up chemical reactions, enzymes attach to a substrate/molecule and break it down so that it can be used throughout the organism. (ipl.org)
A simple change in temperature, a molecule out of place, and a sudden change in the pH level are just some of the things that can harm an enzyme 's reaction rate (the speed at which a chemical reaction proceeds) (5). (ipl.org)

One enzyme starts off by attaching itself to a substrate at the active site, where the two undergo chemical reactions. (ipl.org)
The three things that can cause the enzyme to denature is a large change in pH level, High Temperature, and substrate concentration. (ipl.org)
When we mixed pH 3 enzyme tube with substrate tube, we used 0.3 mL of hydrogen peroxide, but if we were to increase the amount, then the experiment would have been faster. (ipl.org)
In general, immunohistochemical staining allows the visualization of antigens via the sequential application of a specific antibody (primary antibody) to the antigen, a secondary antibody (link antibody) to the primary antibody, an enzyme complex and a chromogenic substrate with interposed washing steps. (roche.com)

The enzyme (represented by a hand) had to catalyze as many substrates as possible (represented by toothpicks) within 60 seconds. (ipl.org)
The enzyme of turnip peroxidase is added in the equation to catalyze the oxidation. (ipl.org)
Abstract: Enzymes can catalyze chemical reactions by speeding up the chemicals activation energy. (ipl.org)
How does an enzyme catalyze a chemical reaction in regards to activation energy? (answers.com)

Although the reaction is reversible in vitro, within the cell the enzyme only works in the forward direction as shown below because the concentration of inorganic phosphate is much higher than that of glucose-1-phosphate. (wikipedia.org)
Mechanistically, we demonstrate that complement activation leading to the decoration of particles/cells with C3- and/or C4-opsonins increased PD-L1 expression on neutrophils and monocytes as shown for different in vitro models of classical or alternative pathway activation. (bvsalud.org)
A key in vitro Mammalian gene Mutation (Assay according to OECD TG 476 was conducted in CHO K1 Chinese hamster ovary cells at the Hprt locus in the presence and absence of a metabolic activation. (europa.eu)
A key in vitro Micronucleus assay according to OECD TG 487 was conducted in human peripheral lymphocytes in the presence and absence of a metabolic activation. (europa.eu)

We conclude that a positive-feedback cascade involving CRAC channels and cysteinyl leukotrienes constitute a novel mechanism for sustaining mast cell activation. (ox.ac.uk)

In the absence of sufficient intracellular dUMP, p53-mediated apoptosis is triggered in activated, but not resting, lymphocytes [ 3 ]. (ersjournals.com)
In a 2010 paper published in Cell , which was co-authored with Wells and postdoctoral fellow Sami Mahrus, PhD , Gray showed that activation of either casapse-3 or -7 alone was sufficient to induce cell apoptosis but not caspase-6. (ucsf.edu)

Studies using these samples found associations between fatal outcomes and elevated liver enzyme levels, renal dysfunction, cytokine dysregulation, and genetic factors. (cdc.gov)

In order to be used for metabolism, it must be converted to glucose-6-phosphate by the enzyme phosphoglucomutase. (wikipedia.org)
Several CYP2C9 gene polymorphisms decrease the activity of the CYP2C9 enzyme and slow the body's metabolism of warfarin. (medlineplus.gov)
For example, the enzyme transketolase is critical to blood sugar metabolism. (onetohome.com)

Due to the hot start nature of the enzyme, reactions can be assembled on the bench at room temperature and transferred to a thermocycler. (neb.com)
Enzymes are a form of protein that lowers activation energy and speeds up reactions as a catalyst. (ipl.org)

In addition, the enzyme transferase shifts a block of 3 glucosyl residues from the outer branch to the other end, and then a α1-6 glucosidase enzyme is required to break the remaining (single glucose) α1-6 residue that remains in the new linear chain. (wikipedia.org)
In the healthy kidney, expression of the enzyme glucose-6-phosphatase (G6p), which controls a key step in glycogen breakdown, is suppressed by insulin. (jci.org)
They show here that the transcription factor Foxo1, which is present in the normal tissue and is weakly expressed in the cell line, is sufficient to restore insulin regulation of transcripts that are sensitive to glucose levels. (jci.org)
Previous work had suggested that Foxo1 binding to the G6p promoter accounts for activation of gene expression by glucose and the corresponding silencing of expression following insulin treatment. (jci.org)
The various enzymes present in honey are glucose oxidase, sucrose diastase, catalase, and acid phosphatase [ 14 - 16 ]. (hindawi.com)

overview Strand-displacement is a undifferentiated dysfunction in which the Met-tRNAi component, harmful, and rare unrepaired activation are found by terminal mannosyl acetylases( foodstuffs) into an Myogenic disability at the research Regulation of an mediator. (evakoch.com)

Aberrant mast cell activation is linked to a variety of allergic diseases, including asthma, eczema, rhinitis, and nasal polyposis, which in combination affect up to 20% of the population in industrialized countries. (ox.ac.uk)

Language": "en", "Country": "XG", "Code": "Intended Use" }, { "Name": "Background Information", "Value": "Cadherin-17, also called liver-intestinal (LI) cadherin or human peptide transporter-1, is a member of the cadherin superfamily. (roche.com)
Initiation of the induction of liver enzymes used for preparation S9 used in this study was 2 September 2019. (europa.eu)

ADENYLATE CYCLASE, the enzyme that produces cyclic AMP, is part of a complex regulatory system that mediates the actions of hormones and neurotransmitters on their target cells. (nih.gov)
This enzyme helps produce hormones called cortisol and corticosterone . (medlineplus.gov)

show that stellate cell DDR2 is phosphorylated in response to collagen stimulation, leading the cells to divide and to express the degradative enzyme MMP2. (jci.org)
Macrophages: Macrophages are involved in killing the target cell by releasing lytic and toxic enzymes at the target site. (news-medical.net)
respiratory and olfactory epithelial cells use endosomal and cell surface pathways, and cell surface pathways require activation by cell surface proteases (e.g. (cdc.gov)
which means one copy of the altered gene in each cell is sufficient to cause the disorder. (medlineplus.gov)
8. RNA-Editing Enzyme ADAR1 p150 Isoform Is Critical for Germinal Center B Cell Response. (nih.gov)
Leukotriene secretion still occurred tens of minutes after stimulation, suggesting a role as a long-lasting trigger in mast cell activation. (ox.ac.uk)
The level of cAMP is increased in association with cancer cell formation through activation of AC‑stimulatory G protein by mutation. (spandidos-publications.com)
This multiple activation of Negatively-charged defect factors fundamental of uncoating the middle cell organization. (evakoch.com)

The cells that express this enzyme adopt an invasive phenotype in culture, which probably explains their ability to invade the subendothelial space and remodel the ECM, replacing the normal basement membrane constituents with fibrotic material. (jci.org)
The process of bacterial spore germination involves membrane permeability changes, ion fluxes and the activation of enzymes that degrade the outer layers of the spore. (kitsunemagic.de)
The S2 transcription hyperphosphorylates annotated by ADAM10 membrane, impairing the activation determined NOTCH3 response NEXT3. (evakoch.com)

Activation of alpha 1-adrenergic receptors increases [Ca+2]i and phosphatidylinositol phosphodiesterase (phospholipase C) activity in the pinealocyte. (nih.gov)
Hence, substitution of serines 744 and 748 with glutamic residues as phospho-mimics bypasses the PKC requirement for PKD1 activation but does not bypass the need for antigen receptors, PLC, or DAG. (figshare.com)

This deepens the understanding of the purposes of an enzyme and what affects each one of them. (ipl.org)
Temperature and pH are just two of the factors that affects enzymes and their involvement with chemicals and the way they function. (ipl.org)
20. Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2. (nih.gov)

The CYP11B1 gene provides instructions for making an enzyme called 11-beta-hydroxylase. (medlineplus.gov)
The CYP11B2 gene provides instructions for making another enzyme called aldosterone synthase, which helps produce aldosterone. (medlineplus.gov)
The CYP2C9 gene provides instructions for making an enzyme that breaks down various substances in the body. (medlineplus.gov)
The VKORC1 gene provides instructions for making a vitamin K epoxide reductase enzyme. (medlineplus.gov)

[ 1 ] Activation of the sympathetic nervous system and of the renin-angiotensin system can have adverse hemodynamic consequences in heart failure. (medscape.com)
These results indicate that activation of the local renin-angiotensin system may play an important role in cardiovascular effects induced by PM. (nih.gov)

Without sufficient magnesium, plants cannot produce chlorophyll effectively. (nuleaffarms.ca)
Of the minerals that you should attempt to consume sufficient amounts of on a regular basis is magnesium. (ndcn.net)
A normal diet contains sufficient magnesium. (ndcn.net)

We and others have reported that in response to a chronic exposure to environmental stressors, in particular UV radiation and PAHs, an activation of AHR and downstream signaling pathways critically contributes to the development of SCC. (frontiersin.org)

Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Content", "Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests. (roche.com)

This is because several of the contaminants in technical grade methoxychlor are directly estrogenic (Kupfer and Bulger 1987b), whereas pure methoxychlor is proestrogenic and requires metabolic activation before exhibiting estrogenic activity (Bulger et al. (cdc.gov)
A key Bacterial Reverse Mutation Assay according to OECD TG 471 was conducted in Salmonella typhimurium TA98, TA100, TA1535 and TA1537 and Escherichia coli (WP2uvrA) in the presence and absence of a metabolic activation. (europa.eu)
This robust activation was sufficient to block three of the four major metabolic pathways. (onetohome.com)

Lipoic acid is one of the acids that is generated by the muscles, and it triggers the production of the enzyme in which helps relax the muscles and give them the energy. (dinoivincere-boxers.com)

This change increases phosphorylase activity up to 25% even in the absence of AMP, and enhances AMP activation further. (wikipedia.org)

3. The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways. (nih.gov)

Standard Reference Material 1648) on the constriction of isolated rat pulmonary artery rings and the activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 mitogen-activated protein kinases (MAPKs) in human pulmonary artery endothelial cells with or without losartan, an antagonist of AT 1 R. UPs at 1-100 μg/mL induced acute vaso-constriction in pulmonary artery. (nih.gov)
Neutrophils: These cells are involved in recognizing pathogenic bacteria, and they act by releasing lytic enzymes and generating reactive oxygen species (ROS) which destroy the invading microbes. (news-medical.net)
Another is granzyme B, an enzyme which is involved in DNA fragmentation within target cells. (news-medical.net)
On activation, mast cells release a variety of signals that target the bronchi and vasculature and recruit other immune cells to the inflammatory site. (ox.ac.uk)
The paracrine signal was identified as a cysteinyl leukotriene because 1) RNAi knockdown or pharmacological block of the 5-lipoxygenase enzyme prevented activated mast cells from stimulating resting cells. (ox.ac.uk)
Low levels of stimulus intensity released sufficient levels of leukotriene to activate resting cells. (ox.ac.uk)
Histological analysis of samples taken from patients revealed clustering of mast cells, often located within 20 microm of each other, a distance sufficient for paracrine signaling by leukotrienes to operate effectively. (ox.ac.uk)
These molecuels have a 12S activation of all members participating to the suggesting small transbilayer for converted cells of molecules and of intake interactions. (erik-mill.de)
Third, WWTR1( TAZ) and YAP1 enzyme ZO-1 and 2 cells( Remue et al. (evakoch.com)

The International Agency for Research on Cancer (IARC) stated that there is sufficient evidence in humans for carcinogenicity from inhalation of crystalline silica in the form of quartz or cristobalite from occupational sources. (nih.gov)
The IARC concluded that there is sufficient evidence in experimental animals for the carcinogenicity of the crystalline silica polymorphs quartz and cristobalite but limited evidence for the carcinogenicity of tridymite. (nih.gov)
The Working Group found inadequate evidence in humans and sufficient evidence in experimental animals for the carcinogenicity. (who.int)
The Panel found limited evidence of carcinogenicity in humans and sufficient evidence in animals. (who.int)

Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes. (figshare.com)

UNC93B pore transactivates induced involved in the increased subunit to glycan infected course 5-phosphate 1( HSV1) activation( HSE), a transcriptional dyslexia during single superfamily of the characteristic consequent ha34( CNS)( Casrouge A et al. (erik-mill.de)

Enzymes are not used up or permanently altered by their environment Peroxidases are found in a range of organisms and function to break down alcohol (H2O2) and creates byproducts of oxygen and water. (ipl.org)
The work of AMPK is majorly energy balance in the body, and it is an enzyme in nature which of found in every living creature and helps a lot to them. (dinoivincere-boxers.com)

if a sufficient sample amount was available, serum chemistry analyses were also performed. (cdc.gov)

Mechanisms are also in place that limit the hemostatic response to the site of injury and prevent further platelet activation. (medscape.com)
It acts as a cofactor in various enzyme systems that are involved in stress response mechanisms, making plants more resilient in challenging conditions. (nuleaffarms.ca)

RtcAB catalytic activity is not required for complex formation with CARF, but is essential yet not sufficient for RtcRAB-dependent transcription activation, implying the need for an additional RNA repair-dependent activating signal. (imperial.ac.uk)
PKC phosphorylates serines 744/748 within the PKD1 catalytic domain, and this is proposed to be necessary and sufficient for enzyme activation. (figshare.com)

In most cases, the activation of ADCC involves the binding of IgG antibodies to antigens, although infestation by invasive helminths and some other parasites, IgE antibodies may be bound to the antigen on the pathogen surface. (news-medical.net)

rather, PKD1 activation has more stringent requirements for integration of dual PLC signals, one mediated by PKCs and one that is PKC-independent. (figshare.com)

Other effects observed in vivo included increased production of tumor necrosis factor-, IL-1 macrophage inflammatory protein-2 expression, and lymphokine release, as well as activation of nuclear transcription factor activator protein-1 and lymphocyte proliferation. (nih.gov)

ATSDR believes that there is sufficient merit in this approach to warrant an attempt at distinguishing between 'less serious' and 'serious' effects. (cdc.gov)

Although hemodynamic factors play an essential role in causing the symptoms, they are not sufficient to explain the progression of the heart failure. (medscape.com)
Thus, judged from several standpoints, N, is an essential component in the activation of adenylate cyclase. (nih.gov)
AMPK works best when enabled and offers a lot of good results depending on the work that is supposed to be done by the enzyme which is an essential work in the body. (dinoivincere-boxers.com)
This contains subunits of IRSs with sufficient proteinases mitochondrial as PI-3K via its Src tyrosine 2( SH2) rRNAs depending to lead function opportunities essential as Glut4( Slc2a4) Impact. (evakoch.com)

Combined actions of three enzymes: lipase, lipoxygenase (LOX) and hydroperoxide lyase (HPL) convert lipidic substrates such as C 18:2 and C 18:3 fatty acids into short chain volatiles. (ac.be)

Calculating the mass of reactants and products in a chemical reaction is a sufficient demonstration. (answers.com)
Any catalyst will make a chemical reaction easier or quicker to happen by lowering the activation energy. (answers.com)

Angiotensin-converting enzyme (ACE) is a zinc metallopeptidase, with primary known functions of converting angiotensin I into the vasoactive and aldosterone-stimulating peptide angiotensin II and inactivating bradykinin. (medscape.com)
Hemostasis is a dynamic and tightly regulated process, with primary hemostasis involving formation of a platelet plug and secondary hemostasis pertaining to activation of the clotting cascade and ultimately the formation of a clot. (medscape.com)
Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "Cadherin-17 (SP183) Rabbit Monoclonal Primary Antibody is intended for laboratory use in the detection of the Cadherin-17 protein in formalin-fixed, paraffin-embedded tissue stained on VENTANA BenchMark IHC/ISH instruments. (roche.com)
Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Principle", "Value": "Cadherin 17 (SP183) Rabbit Monoclonal Primary Antibody (this antibody) may be used as the primary antibody for immunohistochemical staining of formalin-fixed, paraffinembedded tissue sections. (roche.com)

3. Treatment of DNA polymerase alpha A1 with the phospholipase C hydrolysis product of phosphatidylinositol-4-monophosphate, inositol-1,4-bisphosphate, was sufficient to effect the transient increase in activity of polymerase A1 to a form not chromatographically distinguishable from isozyme form A2. (nih.gov)

Here, we demonstrate that RtcAB are required for RtcR-dependent transcription activation and directly bind to RtcR CARF. (imperial.ac.uk)

An enzyme is a type protein that is able to speed up over 5,000 different reaction types an organism (2). (ipl.org)
the in vivo rate of sulfate activation in penicillium chrysogenum (wild-type strain atcc 24791) was determined to be 0.19 +/- 0.09 mumol g(-1) (dry weight) min(-1) by the following methods. (liverpool.ac.uk)

The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. (roche.com)

Like many enzymes, transketolase requires a co-factor. (onetohome.com)

The angiotensin-converting enzyme (ACE) inhibitors are very important in the therapy of heart failure. (medscape.com)
The conditions that were present in the lab showed that the enzyme is exposed is not perfect at all times and that the effect that they have is vitally important to the performance of the enzyme, and more importantly, the organism that it is living in. (ipl.org)

Anatomy5

Organisms4

Chemicals and Drugs24

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes22

Information Science3

Inhibition5

Proteins6

Biochemical3

Genes4

Denaturation2

Photosynthesis2

Ligase2

Phosphorylation7

Neurons4

Cytoplasmic2

Lipid5

Inhibit2

Receptor5

Molecule2

Substrate4

Catalyze4

Vitro4

Mechanism1

Apoptosis2

Renal1

Metabolism3

Reactions2

Glucose5

Regulation1

Aberrant1

Liver2

Hormones2

Cell8

Membrane3

Receptors2

Affects3

Gene4

Renin-angiot2

Magnesium3

Contributes1

Contains sufficient1

Metabolic3

Triggers1

Absence1

Pathways1

Cells9

Carcinogenicity4

Lymphocytes1

Transcriptional1

Found2

Analyses1

Mechanisms2

Catalytic2

Involves1

Signals1

Transcription factor1

Effects1

Essential4

Convert1

Chemical reaction2

Primary4

Activity1

Demonstrate1

Type2

Results1

Requires1

Important2