Loading...
  • kinase
  • Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin. (nih.gov)
  • proteins
  • These include activation of transcription factors, expression of specific cell-surface proteins, reorganization and expression of cytoskeletal proteins, production of ECM-degrading enzymes, and changes in the expression of specific microRNAs. (jci.org)
  • noggin
  • Nor are they activated in animal cap, neither by noggin nor by Xnr3, suggesting that a different inducer or the integration of several signals may be responsible for their activation (Pannese, 1998). (sdbonline.org)
  • secretion
  • hCG and transforming growth factor- (TGF-) β increase LIF secretion by the cultured endometrial epithelial cells derived from follicular and secretory phases of the menstrual cycle [ 15 ]. (hindawi.com)
  • activity
  • Based on our current understanding of Myod, it is reasonable to suggest that the regulated activity of a single factor that broadly interacts with many cellular components might be a common mechanism for orchestrating a complex response to an initiating event. (biologists.org)