Activates downstream effector caspases. Medical search. Frequent questions

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Anatomy19

Mitochondria Jurkat Cells Cell Line Tumor Cells, Cultured Cells, Cultured Cell Line, Tumor HeLa Cells CD8-Positive T-Lymphocytes T-Lymphocytes COS Cells Fibroblasts Cell Nucleus HL-60 Cells Neurons Cell Membrane CD4-Positive T-Lymphocytes 3T3 Cells Cytoskeleton NIH 3T3 Cells

Organisms3

Mice, Inbred C57BL Mice, Knockout Mice, Transgenic

Chemicals and Drugs101

Caspases, Effector Caspases Caspase Inhibitors Caspase 7 Caspase 9 Caspase 3 Amino Acid Chloromethyl Ketones Caspase 6 X-Linked Inhibitor of Apoptosis Protein Caspase 8 Cysteine Proteinase Inhibitors Apoptosomes Apoptotic Protease-Activating Factor 1 Inhibitor of Apoptosis Proteins Antigens, CD95 Cytochromes c Poly(ADP-ribose) Polymerases Cytochrome c Group BH3 Interacting Domain Death Agonist Protein Proto-Oncogene Proteins c-bcl-2 bcl-2-Associated X Protein Enzyme Inhibitors Apoptosis Regulatory Proteins Carrier Proteins Proteins Drosophila Proteins TNF-Related Apoptosis-Inducing Ligand Mitochondrial Proteins Protein-Serine-Threonine Kinases Caspase 2 Caspases, Initiator Proto-Oncogene Proteins c-akt Phosphatidylinositol 3-Kinases Intracellular Signaling Peptides and Proteins Proto-Oncogene Proteins rho-Associated Kinases Adaptor Proteins, Signal Transducing cdc42 GTP-Binding Protein ras Proteins Caspase 1 rhoA GTP-Binding Protein rho GTP-Binding Proteins Cysteine Endopeptidases Mitogen-Activated Protein Kinases p21-Activated Kinases RNA, Small Interfering Transcription Factors TOR Serine-Threonine Kinases rac1 GTP-Binding Protein DNA-Binding Proteins Recombinant Fusion Proteins Recombinant Proteins Membrane Proteins RNA, Messenger Guanine Nucleotide Exchange Factors Chromones Caspase 10 Proto-Oncogene Proteins c-raf Protein Kinases bcl-X Protein rac GTP-Binding Proteins Phosphoproteins Morpholines Nuclear Proteins JNK Mitogen-Activated Protein Kinases Tumor Suppressor Protein p53 Oligopeptides ral GTP-Binding Proteins Ribosomal Protein S6 Kinases, 90-kDa Fas Ligand Protein Extracellular Signal-Regulated MAP Kinases GTP Phosphohydrolases Actins Antineoplastic Agents p38 Mitogen-Activated Protein Kinases Granzymes Ribosomal Protein S6 Kinases, 70-kDa Tumor Necrosis Factor-alpha Tumor Suppressor Proteins Trans-Activators GTPase-Activating Proteins Isoenzymes Membrane Glycoproteins GTP-Binding Proteins Cell Cycle Proteins NF-kappa B rab GTP-Binding Proteins Bacterial Proteins Protein Kinase Inhibitors Proto-Oncogene Proteins p21(ras)Fas-Associated Death Domain Protein Lim Kinases Protein-Tyrosine Kinases raf Kinases Enzyme Precursors Ribosomal Protein S6 Kinases DNA Primers Protein Kinase C Apoptosis Inducing Factor Staurosporine Amides

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Models, Biological Blotting, Western Transfection Flow Cytometry In Situ Nick-End Labeling Immunoblotting Reverse Transcriptase Polymerase Chain Reaction Lymphocyte Activation Immunoprecipitation Microscopy, Fluorescence Two-Hybrid System Techniques Immunohistochemistry

Phenomena and Processes41

Apoptosis Enzyme Activation Signal Transduction Cell Death DNA Fragmentation Phosphorylation Protein Binding Amino Acid Sequence Cell Proliferation Cell Survival Transfection Mutation Protein Structure, Tertiary Cell Differentiation Gene Expression Regulation MAP Kinase Signaling System Protein Transport Down-Regulation Cell Movement Up-Regulation Time Factors RNA Interference Lymphocyte Activation Cell Cycle Binding Sites Immunologic Memory Cell Division Base Sequence Transcription, Genetic Sequence Homology, Amino Acid Phenotype Dose-Response Relationship, Drug Substrate Specificity Cytotoxicity, Immunologic Gene Expression Regulation, Developmental Protein Processing, Post-Translational Gene Expression Regulation, Neoplastic Gene Expression Gene Expression Regulation, Enzymologic Genes, ras Kinetics

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Caspases, Effector Caspases Caspase Inhibitors Caspase 7 Apoptosis Caspase 9 Caspase 3 Amino Acid Chloromethyl Ketones Caspase 6 X-Linked Inhibitor of Apoptosis Protein Caspase 8 Cysteine Proteinase Inhibitors Enzyme Activation Apoptosomes Apoptotic Protease-Activating Factor 1 Inhibitor of Apoptosis Proteins Signal Transduction Antigens, CD95 Cytochromes c Mitochondria Poly(ADP-ribose) Polymerases Cytochrome c Group Jurkat Cells BH3 Interacting Domain Death Agonist Protein Proto-Oncogene Proteins c-bcl-2 Cell Death bcl-2-Associated X Protein Cell Line DNA Fragmentation Enzyme Inhibitors Apoptosis Regulatory Proteins Carrier Proteins Proteins Models, Biological Tumor Cells, Cultured Drosophila Proteins TNF-Related Apoptosis-Inducing Ligand Mitochondrial Proteins Phosphorylation Protein-Serine-Threonine Kinases Cells, Cultured Caspase 2 Caspases, Initiator Cell Line, Tumor Proto-Oncogene Proteins c-akt Phosphatidylinositol 3-Kinases Molecular Sequence Data Intracellular Signaling Peptides and Proteins Protein Binding Amino Acid Sequence Mice, Inbred C57BL Proto-Oncogene Proteins Mice, Knockout rho-Associated Kinases Cell Proliferation Blotting, Western Adaptor Proteins, Signal Transducing cdc42 GTP-Binding Protein Cell Survival Transfection ras Proteins Mutation Caspase 1 Protein Structure, Tertiary rhoA GTP-Binding Protein rho GTP-Binding Proteins Cysteine Endopeptidases Mitogen-Activated Protein Kinases p21-Activated Kinases RNA, Small Interfering Transcription Factors TOR Serine-Threonine Kinases Mice, Transgenic Cell Differentiation Gene Expression Regulation rac1 GTP-Binding Protein HeLa Cells DNA-Binding Proteins MAP Kinase Signaling System Recombinant Fusion Proteins Protein Transport Flow Cytometry Recombinant Proteins Membrane Proteins Down-Regulation Cell Movement Up-Regulation RNA, Messenger Guanine Nucleotide Exchange Factors In Situ Nick-End Labeling CD8-Positive T-Lymphocytes Chromones Caspase 10 Proto-Oncogene Proteins c-raf Time Factors RNA Interference Protein Kinases bcl-X Protein Immunoblotting rac GTP-Binding Proteins

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