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  • neuron
  • An action potential (AP) is the mode through which a neuron transports electrical signals. (teachmephysiology.com)
  • For years, neuroscientists have been trying to develop tools that would allow them to clearly view the brain's circuitry in action-from the first moment a neuron fires to the resulting behavior in a whole organism. (caltech.edu)
  • signals
  • In this course, you will discover the organization of the neural systems in the brain and spinal cord that mediate sensation, motivate bodily action, and integrate sensorimotor signals with memory, emotion and related faculties of cognition. (coursera.org)
  • Furthermore, we characterized the signal to noise ratio of action potential signals of varying sets of cameras, dye concentrations and objective lenses. (spie.org)
  • Muscle contractions are signaled by action potentials (electrical signals) in the plasma membranes of muscle fibers. (bodybuilding.com)
  • spike
  • Neural oscillations are observed throughout the central nervous system at all levels, and include spike trains , local field potentials and large-scale oscillations which can be measured by electroencephalography (EEG). (wikipedia.org)
  • extracellular
  • 5) State the "big 5" electrical field variables (potentials, field, force, current, sources) and be able to compute potentials from sources (the basis of extracellular bioelectric measurements such as the electrocardiogram) or find sources from potentials. (coursera.org)
  • In addition, cell membranes are involved in a variety of cellular processes such as cell adhesion , ion conductivity and cell signalling and serve as the attachment surface for several extracellular structures, including the cell wall , the carbohydrate layer called the glycocalyx , and the intracellular network of protein fibers called the cytoskeleton . (wikipedia.org)
  • Electrical extracellular recordings, i.e., recordings of the electrical potentials in the extracellular medium between cells, have been a main work-horse in electrophysiology for almost a century. (frontiersin.org)
  • Here, we describe LFPy , an open source Python package for numerical simulations of extracellular potentials. (frontiersin.org)
  • Further, calculation of extracellular potentials using the line-source-method is efficiently implemented. (frontiersin.org)
  • We describe the theoretical framework underlying the extracellular potential calculations and illustrate by examples how LFPy can be used both for simulating LFPs, i.e., synaptic contributions from single cells as well a populations of cells, and MUAs, i.e., extracellular signatures of action potentials. (frontiersin.org)
  • Hodgkin
  • In 1952, Hodgkin and Huxley published an empirical set of equations describing changes in the neural membrane potential of the squid giant axon during the application of depolarizing or hyperpolarizing stimuli. (scielo.org.za)
  • This study proposes possible modifications of the Hodgkin-Huxley equations to describe action potentials generated in the Ranvier node of a human sensory nerve fibre, as applied specifically to the prediction of temporal characteristics of the human auditory system. (scielo.org.za)
  • The action potential can be modeled by solving the Hodgkin-Huxley equations, a set of nonlinear ordinary differential equations. (wolfram.com)
  • conductance
  • In subsequent data analysis, we determined action potential phase-locking profiles with respect to background conductance, average firing rate, and frequency of the sinusoidal component. (jneurosci.org)
  • In particular, higher average spiking rates promoted bandpass profiles, and the high-conductance state promoted phase-locking at frequencies well above what would be predicted from changes in the membrane time constant. (jneurosci.org)
  • this bombardment leads to increased membrane conductance and highly irregular membrane potential fluctuations, which drive spiking. (jneurosci.org)
  • Dynamic-clamp technology allows the introduction of membrane voltage fluctuations and conductance to cells in vitro . (jneurosci.org)
  • neural
  • The potential for relapse following cessation of drug use can last for years, implying the induction of stable changes in neural circuitry. (jneurosci.org)