• Nineteen different serotype variants (serovars) have been recognized for A. pleuropneumoniae, based on the different capsular polysaccharides exhibited. (wikipedia.org)
  • Cell-free extracts isolated from colony biofilms of Actinobacillus pleuropneumoniae serotype 5 were found to inhibit biofilm formation by Staphylococcus aureus, S. epidermidis and Aggregatibacter actinomycetemcomitans, but not by A. pleuropneumoniae serotype 5 itself, in a 96-well microtiter plate assay. (vt.edu)
  • Our findings suggest that the A. pleuropneumoniae serotype 5 capsule inhibits cell-to-cell and cell-to-surface interactions of other bacteria. (vt.edu)
  • A. pleuropneumoniae serotype 5 capsular polysaccharide is one of a growing number of bacterial polysaccharides that exhibit broad-spectrum, nonbiocidal antibiofilm activity. (vt.edu)
  • Actinobacillus pleuropneumoniae (previously Haemophilus pleuropneumoniae), is a Gram-negative, facultative anaerobic, respiratory pathogen found in pigs. (wikipedia.org)
  • The typical presentation of A. pleuropneumoniae in pigs is the characteristic demarcated lesions in the middle, cranial, and caudal lobes of the lungs. (wikipedia.org)
  • The objectives of this study were to elucidate at which age tonsillar colonisation by Actinobacillus pleuropneumoniae occurs in pigs and relate this occurrence to the presence of colostral antibodies to A. pleuropneumoniae. (dtu.dk)
  • The pigs were examined repeatedly for the presence of A. pleuropneumoniae on the tonsils and for antibodies to A. pleuropneumoniae using bacteriological and serological techniques, respectively. (dtu.dk)
  • The cumulative proportion of pigs carrying A. pleuropneumoniae in their tonsils increased significantly between the age of 4-12 weeks. (dtu.dk)
  • This age period corresponded to the age at which the proportion of pigs with detectable levels of colostral antibodies to the different serotypes of A. pleuropneumoniae was declining. (dtu.dk)
  • Actinobacillus pleuropneumoniae hfq mutants strains are attenuated for virulence in pigs , impaired in the ability to form biofilms , and more susceptible to stress, but knowledge of the extent of sRNA involvement is limited. (bvsalud.org)
  • The Ceva Lung Program offers the methodology and guidelines on how to correctly evaluate the presence, incidence, circulation patterns and impact of Mycoplasma hyopneumoniae , Actinobacillus pleuropneumoniae and Aujesky's disease virus infections using serological investigation and adapted lung scoring of slaughter pigs. (ceva.vn)
  • Swine and Calves: Use for the control and treatment of bacterial enteritis (scours) caused by E.coli and bacterial pneumonia associated with Actinobacillus pleuropneumoniae, Pasteurella spp. (valleyvet.com)
  • Tilmicosin is also indicated for the control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae and Pasteurella multocida. (affygility.com)
  • About 18 species have been described within genus Actinobacillus , but the relationship between members within the closely related genera Actinobacillus , Haemophilus , Mannheimia and Pasteurella is very uncertain since none of these genera forms monophyletic clusters. (vetbact.org)
  • The causal organism is Actinobacillus pleuropneumoniae (APP). (biostoneah.com)
  • A derivative of erythromycin, it is active against Actinobacillus pleuropneumoniae (APP), P asteurella multocida , Bordetella bronchiseptica , Haemophilus parasuis and Mycoplasma hyopneumoniae ( M. hyo ) - all pathogens that can cause or contribute to SRD. (thepigsite.com)
  • Kylt ® Actinobacillus pleuropneumoniae (APP) Real-Time PCR Detection products are intended for the detection of Actinobacillus pleuropneumoniae (APP), the cause of Pleuropneumonia. (kylt.eu)
  • The complexity of the pathogenic mechanism underlying the host immune response to Actinobacillus pleuropneumonia ( App ) makes the use of preventive measures difficult, and a more global view of the host-pathogen interactions and new insights into this process are urgently needed to reveal the pathogenic and immune mechanisms underlying App infection. (biomedcentral.com)
  • Actinobacillus pleuropneumonia ( App ) can cause serious porcine respiratory diseases with high incidence and mortality rates. (biomedcentral.com)
  • This invention discloses the DNA sequences coding for the Actinobacillus pleuropneumonia hemolysin(s). (tamu.edu)
  • Of these diseases, epididymitis and orchitis in rams (caused by A. seminis ), sleepy foal disease (caused by A. equuli ), porcine pleuropneumonia (caused by A. pleuropneumoniae ) and pyogranulomatous lesions of the soft tissues of the head - in particular the oral cavity or the forestomachs of cattle, sheep and goats - (caused by A. lignieresii) occur most commonly. (anipedia.org)
  • Differences in virulence potential, immunogenicity, and worldwide geographical distribution contribute to the diversity of the A. pleuropneumoniae serotypes. (wikipedia.org)
  • Actinobacillus pleuropneumoniae is a nonmotile, Gram-negative, encapsulated coccobacillus bacterium found in the family Pasteurellaceae. (wikipedia.org)
  • Here, using A. pleuropneumoniae strain MIDG2331 ( serovar 8), 14 sRNAs were identified by co-immunoprecipitation with Hfq and the expression of eight, identified as trans-acting sRNAs, were confirmed by Northern blotting . (bvsalud.org)
  • Objective】 Through genome sequencing and bioinformatics analysis of GD2107 strain of multi-drug resistant Actinobacillus pleuropneumoniae (APP),the genome database information of APP was enriched,the phylogenetic tree based on Apx Ⅳ gene was constructed,and the evolutionary relationship of the strain was analyzed,so as to provide reference for exploring the pathogenic mechanism of APP and clinical prevention and control of porcine infectious porcine contagious pleuropneumia (PCP). (chvm.net)
  • Whole Genome Sequencing and Biological Characteristics Analysis of Multidrug-resistant Actinobacillus pleuropneumoniae GD2107 Strain[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(10): 4019-4031. (chvm.net)
  • Most strains of A. pleuropneumoniae , biotype I require V-factor (NAD or NADPH) for growth, while strains of biotype II does not require this factor. (vetbact.org)
  • Actinobacillus equuli, A. lignieresii, A. rossii and A. suis grow readily on ordinary bacterial growth media. (anipedia.org)
  • 3] SHIN M,KANG M L,CHA S B,et al.An immunosorbent assay based on the recombinant ApxⅠa,ApxⅡa,and ApxⅢa toxins of Actinobacillus pleuropneumoniae and its application to field sera[J]. Journal of Veterinary Diagnostic Investigation ,2011,23(4):736-742. (chvm.net)
  • The Real-Time PCR Detection Kit contains all reagents and controls for the secure and precise detection of Actinobacillus pleuropneumoniae. (kylt.eu)
  • The AsurDx TM Actinobacillus pleuropneumoniae (APP) Antibody Test Kit is designed for the detection of pig antibodies specific to Actinobacillus pleuropneumoniae (APP). (biostoneah.com)
  • 5] STRINGER O W,LI Y,BOSS J T,et al.Rapid detection of Actinobacillus pleuropneumoniae from clinical samples using recombinase polymerase amplification[J]. Frontiers in Veterinary Science ,2022,9:805382. (chvm.net)
  • The methods were developed and applied using purified LPS of Escherichia coli and Salmonella enterica, as well as more complex LPS of Actnobacillus pleuropneumoniae. (nih.gov)
  • 1] ZHANG L,WU X,HUANG Z,et al.Pharmacokinetic/pharmacodynamic assessment of cefquinome against Actinobacillus pleuropneumoniae in a piglet tissue cage infection model[J]. Veterinary Microbiology ,2018,219(6):100-106. (chvm.net)
  • 14 However, A. pleuropneumoniae requires a Staphylococcus feeder culture, or a nicotinamide adenine dinucleotide (NAD) supplement in media intended for its growth. (anipedia.org)
  • Several virulence factors account for the remarkable pathogenicity of A. pleuropneumoniae. (wikipedia.org)
  • This work increases our understanding of the multilayered and complex nature of the influence of Hfq-dependent sRNAs on the physiology and virulence of A. pleuropneumoniae. (bvsalud.org)
  • It further discloses a method of producing the A. pleuropneumoniae hemolysin(s) from recombinant cells. (tamu.edu)
  • 18. Ito H, Takahashi S, Asai T, Tamura Y, Yamamoto K. Isolation and molecular characterization of a urease-negative Actinobacillus pleuropneumoniae mutant. (gifu-u.ac.jp)
  • Actinobacillus colonies are small, greyish and may be 'sticky' on primary isolation. (anipedia.org)
  • The forms of pleurisy located in the dorso-caudal region are primarily caused by Actinobacillus pleuropneumoniae ( A.p. ) and to a lesser extent by other pathogens. (ceva.vn)
  • In addition, the SHIC Rapid Response Team's investigations of an Actinobacillus pleuropneumoniae (App) outbreak in the Midwest exposed deficiencies of wean-to-harvest biosecurity in the area that contributed to the disease spread. (pigprogress.net)
  • A. pleuropneumoniae wild-type extracts did not inhibit S. aureus growth, but did inhibit S. aureus intercellular adhesion and binding of S. aureus cells to stainless steel surfaces. (vt.edu)
  • A. pleuropneumoniae was detected in the tonsils of one pig as early as 11 days after birth, showing that A. pleuropneumoniae can be transmitted from sow to offspring during a 3-week nursing period. (dtu.dk)