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  • cellular
  • The classic cadherin subfamily includes N-, P-, R-, B-, and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells. (cellsignal.com)
  • Here, we report on recent neutron measurements performed directly in living cells by using isotope labelling to explore the dynamics of specific cellular components. (royalsocietypublishing.org)
  • Cellular microbiology is a discipline that bridges microbiology and cell biology. (wikipedia.org)
  • Cellular microbiology attempts to use pathogenic microbes as tools for cell-biology research, and to employ cell-biology methods to understand the pathogenicity of microbes. (wikipedia.org)
  • Recently, the field of Cellular Microbiology has been expanded to incorporate investigation of the cell biology of microbes themselves. (wikipedia.org)
  • An asymmetric cell division produces two daughter cells with different cellular fates. (wikipedia.org)
  • Antibody
  • This Cell Signaling Technology┬« antibody is conjugated to the carbohydrate groups of horseradish peroxidase (HRP) via its amine groups. (cellsignal.com)
  • When a B cell is activated by its first encounter with an antigen that binds to its receptor (its "cognate antigen"), the cell proliferates and differentiates to generate a population of antibody-secreting plasma B cells and memory B cells. (wikipedia.org)
  • BCR functions are required for normal antibody production, and defects in BCR signal transduction may lead to immunodeficency, and B-cell malignancy. (wikipedia.org)
  • Observations in common include: cytoplasmic displacement at leading edge (front) laminar removal of dorsally-accumulated debris toward trailing edge (back) The latter feature is most easily observed when aggregates of a surface molecule are cross-linked with a fluorescent antibody or when small beads become artificially bound to the front of the cell. (wikipedia.org)
  • adhesion
  • It has also been proposed that microdomain interaction marks the formation of new focal adhesion sites at the cell periphery. (wikipedia.org)
  • Finally, continuous application of stress on the old focal adhesion sites could result in the calcium-induced activation of calpain, and consequently the detachment of focal adhesions which completes the cycle. (wikipedia.org)
  • elongation
  • Play media Initiation Consists of a number of different possible mechanisms that ultimately determine where and when actin filament elongation is to occur. (wikipedia.org)
  • The elongation phase begins when the concentration of short, F-actin polymers is significantly larger than at equilibrium. (wikipedia.org)
  • biases
  • By decreasing the relative proportion of dividing Lm, actin polymerization biases the population toward cells with the highest propensity to form actin tails. (umass.edu)
  • Numb is a suppressor of Notch, therefore the asymmetric segregation of Numb to the basal cortex biases the response of the daughter cells to Notch signaling, resulting in two distinct cell fates. (wikipedia.org)
  • cytoplasm
  • These pseudopodia are subsequently shed as cytoplasm-containing vesicles, resulting in the formation of a groove in medulla cells that is filled with tonofilament bundles originating from cortex cells ( Morioka, 2005 ). (biologists.org)
  • Movement occurs when the cytoplasm slides and forms a pseudopodium in front to pull the cell forward. (wikipedia.org)
  • bound
  • The separate nuclei are bound by a nuclear bridge and in binucleated cells the centrioles are doubled. (wikipedia.org)
  • occurs
  • At cytokinesis, the last phase of the cell cycle, rapid dephosphorylation of stathmin occurs to block the cell from entering back into the cell cycle until it is ready. (wikipedia.org)
  • The single cell is now set up to undergo an asymmetric cell division, however the orientation in which the division occurs is also an important factor. (wikipedia.org)
  • progression
  • What remains unclear is whether or how epithelial cells link spindle position to cell cycle progression. (rupress.org)
  • Furthermore, elevated growth factor signaling may suppress the ubiquitinating action of RICTOR-FBXW7, resulting in accumulation of cyclin E and c-Myc and subsequent progression through the cell cycle. (wikipedia.org)
  • epithelial cells
  • Investigators have also demonstrated that expression of P-cadherin, which is normally present in epithelial cells, is also altered in ovarian and other human cancers (7,8). (cellsignal.com)
  • Larson and Bement, 2017 ), suggesting that epithelial cells can delay anaphase until the spindle has achieved the correct position and orientation. (rupress.org)
  • contractile
  • The alpha actins, found in muscle tissues, are a major constituent of the contractile apparatus. (wikipedia.org)
  • Another group found that CB inhibits the ability of HeLa cells to undergo cytokinesis by decomposition of the contractile ring. (wikipedia.org)