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Adherens JunctionsDesmosomesIntermediate FilamentsIntermediate Filament ProteinsActinsDesmoplakinsVimentinIntercellular JunctionsCadherinsDesmogleinsgamma CateninCytoskeletonKeratinsActin CytoskeletonDesminDesmocollinsalpha CateninTight JunctionsCytoskeletal ProteinsPlakophilinsCateninsGap JunctionsMicroscopy, ElectronActin Depolymerizing Factorsbeta CateninCell AdhesionFluorescent Antibody TechniqueZonula Occludens-1 ProteinArmadillo Domain ProteinsVinculinEpithelial CellsCell Adhesion MoleculesMicroscopy, FluorescenceDesmoglein 1EpitheliumPlakinsMolecular Sequence DataCells, CulturedMicrofilament ProteinsEpidermisDesmoglein 2Desmosomal CadherinsPlectinCell LineMembrane ProteinsProtein BindingAmino Acid SequenceMyosinsDesmoglein 3Keratin-8PeripherinsActin Capping ProteinsCell PolarityNestinCell CommunicationOccludinMicroscopy, ImmunoelectronNeurofilament ProteinsKeratinocytesGlial Fibrillary Acidic ProteinDogsPhosphoproteinsMicrotubulesMutationImmunohistochemistryModels, BiologicalNeuromuscular JunctionPhalloidineProtein Structure, TertiaryPhosphorylationLaminsCell MovementBase SequenceCytoplasmMicroscopy, ConfocalPemphigusSignal TransductionActininCell MembraneCattleDrosophila ProteinsConnexin 43RabbitsNerve Tissue ProteinsTropomyosinMuscle ProteinsChickensMolecular WeightTransfectionMicroscopy, Electron, TransmissionTrans-ActivatorsGelsolinElectrophoresis, Polyacrylamide GelCytochalasin DKeratin-18ActomyosinMorphogenesisDipodomysRecombinant Fusion ProteinsCalcium

Sites for actinCytoskeletonProteinsMacula adherensIntercellular junctionsDesmoplakinEpithelial cellsCadherinsAdjacentFocal AdhesionsInteractsAdhesionsJunctionalMyosinIntegrinsBundlesMembraneStructuralPolymerizationCadherinTightCells togetherRegulationConnectTypes of cellIncludeComplexPlasmaAttachAnimalBlueRegion

Sites for actin1

• Fascia adherens are anchoring sites for actin, and connect to the closest sarcomere. (wikipedia.org)

Cytoskeleton2

• An intracellular domain that interacts with actin filaments of the cytoskeleton (sometimes with intermediate filaments), an extracellular domain that binds collagen, fibronectins and laminins, and an intramembrane domain containing hydrophobic amino acid sequences inserted among the lipid fatty acid chains. (uvigo.es)
• They are patch like adhesions complexes that are intracellularly connected with the intermediate filaments of the cytoskeleton. (uvigo.es)

Proteins5

• These adhesion proteins(desmoglein and desmocollin), like those at an adherens junction, belong to thecadherin family. (ostatic.com)
• The transmembrane adhesion proteins in these cell-matrixjunctions are integrins a large family of proteins distinct from the cadherins.Focal adhesions enable cells to get a hold on the extracellular matrix through integrins that link intracellularly to actin filaments. (ostatic.com)
• The abstract states, "Glutathione-S-transferase (GST) pulldown assays were used to show that RPTPrho interacts with several adherens junctional proteins in brain, including E-cadherin, N-cadherin, VE-cadherin (cadherin-5), desmoglein, alpha, beta [Ctnnb1] and gamma [Jup] catenin, p120(ctn) and alpha-actinin. (geneontology.org)
• The contractile ring is made up of structural proteins, including actin filaments and myosin II filaments. (jove.com)
• The extracellular domain of cadherines, the adhesion proteins of desmosomes, are responsible for cell-cell recognition and adhesion. (uvigo.es)

Macula adherens1

• macula adherens) it is type of cell-cell junction. (uvigo.es)

Intercellular junctions1

• In polarized epithelium, adhesion between adjacent cells is mediated by intercellular junctions, namely, tight junctions, adherens junctions, and desmosomes [14] . (plos.org)

Desmoplakin2

• In airway epithelial cells, altered AQP5 abundance is associated with changes in actin organization and in desmoplakin localization, which could contribute to the changes in paracellular permeability. (plos.org)
• The particular type of intermediate filaments attached tothe desmosomes depends on the cell type: they are keratin filaments in mostepithelial cells, for example, and desmin filaments in heart muscle cells.The junction hasa dense cytoplasmic plaque composed of a complex of intracellular anchorproteins (plakoglobin and desmoplakin) that are responsible for connecting thecytoskeleton to the transmembrane adhesion proteins. (ostatic.com)

Epithelial cells4

• The assembly of tight junctions between epithelial cells seems to require theprior formation of adherens junctions. (ostatic.com)
• These antibodies bindto and disrupt the desmosomes that hold their skin epithelial cells(keratinocytes) together. (ostatic.com)
• Adherens junctions are a ubiquitous type of intercellular junction and are present in both epithelial and non-epithelial cells [ 3 , 6 ], whereas desmosomes are adhesive junctions that confer tensile strength and resilience on cells and are present not only in epithelial cells but also in non-epithelial cells that endure mechanical stress, such as cardiac muscle and meninges [ 7 . (oncotarget.com)
• The caption states, "In the larval eye disc, Arm is present at the apical junctions of all epithelial cells but concentrated at points of photoreceptor contact. (geneontology.org)

Cadherins1

• It is created by the linkage of cadherins and intermediate filaments. (conceptsmedias.com)

Adjacent5

• Through desmosomes, the intermediatefilaments of adjacent cells are linked into a net that extends throughout themany cells of a tissue. (ostatic.com)
• Intercalated discs conduct electrochemical potentials directly between the cytoplasms of adjacent cells via gap junctions . (wikidoc.org)
• Desmosomes *act as rivets to hold adjacent cells together when epithelial tissue moves Gap junctions *allow movement of cytosol, ions, and small molecules between animal cells Plasmodesmata *openings through the cell walls of plant cells that allow adjacent cells to share materials. (conceptsmedias.com)
• the green-colored pigment chlorophyll that converts the energy of sunlight into gap junctions adhering junctions tight junctions free surface of epithelial tissue plasmodesma ER cytoplasm plasma membrane cell wall B Plasmodesmata are channels that connect the cytoplasm and ER of adjacent plant … cell to function properly. (conceptsmedias.com)
• Here, myosin filaments move toward the plus end of adjacent antiparallel actin filaments. (jove.com)

Focal Adhesions2

• This results in a severe blistering of the skin, withleakage of body fluids into the loosened epithelium.Anchoring Junctions Formed by Integrins Bind Cells to theExtracellular Matrix: Focal Adhesions andHemidesmosomesSome anchoring junctions bind cells to the extracellular matrix rather than toother cells. (ostatic.com)
• These are structures known as focal adhesions and adhesion junctions. (uvigo.es)

Interacts1

• At the adherens junction in epithelia, the C-terminal domain of E-cadherin interacts, in a mutually exclusive manner, with β-catenin or γ-catenin (plakoglobin), which then interacts with α-catenin, an actin-binding protein. (oncotarget.com)

Adhesions1

• At the lamellipodium-lamellum interface, unstable adhesions disappear and stable ones start to elongate in a centripetal fashion along the direction of actin retrograde flow. (mechanobio.info)

Junctional2

• The structural integrity of these tissues requires extensive cell-cell adhesion and interactions mediated by the adhesive junctional complexes consisting of the adherens junctions and desmosomes [ 2 - 5 ]. (oncotarget.com)
• Please check the GO:0045177 "apical part of cell" annotation from MGI:3037622/PMID 15037549, which states, "beta-catenin, f-actin, and myosin II-B localize predominantly to the apical-junctional complex in normal neuroepithelium (Fig. 6E-G)." Is there additional supporting evidence for the 45177 annotation? (geneontology.org)

Myosin1

• RhoA activity results in the assembly of myosin II and anti-parallel actin filaments into the structure of the contractile ring. (jove.com)

Integrins1

• In hemidesmosomes, the cytosolic domains of integrins are connected to intermediate filaments, instead of actin filaments. (uvigo.es)

Bundles2

• Adherens Junctions Connect Bundles of Actin Filaments from Cell to Cell. (ostatic.com)
• Likewise,when cultured fibroblasts migrate on an artificial substratum coated withextracellular matrix molecules, they also grip the substratum at focaladhesions, where bundles of actin filaments terminate. (ostatic.com)

Membrane2

• Desmosomes prevent separation during contraction by binding intermediate filaments, anchoring the cell membrane to the intermediate filament network, joining the cells together. (wikipedia.org)
• cell-cell communication The tight junctions and desmosomes are absent between cells, though Animal cells are eukaryotic cells with a membrane-bound Plas… There are different types of animals per se, depending on the type of environment they live in and the kind of lifestyle they have. (conceptsmedias.com)

Structural1

• Inside the cell, they serve as anchoring sites forropelike intermediate filaments, which form a structural framework of greattensile strength. (ostatic.com)

Polymerization1

• RhoA promotes localized actin filament polymerization which is necessary for the contractile ring formation. (jove.com)

Cadherin2

• Anti-cadherin antibodies that block theformation of adherens junctions, for example, also block the formation of tightjunctions.Desmosomes Connect Intermediate Filaments from Cell toCellDesmosomes are buttonlike points of intercellular contact that rivet cellsTogether. (ostatic.com)
• 8 ]. Both adherens junctions and desmosomes are cadherin based. (oncotarget.com)

Tight3

• On the contrary, in animal cells, tight junctions and desmosomes are present between cells. (conceptsmedias.com)
• Among the different types of cell junctions, the Tight Junction directs the movement … turgidity of the cell. (conceptsmedias.com)
• Plant and animal cells have tight junctions, adherent junctions, and gap junctions. (conceptsmedias.com)

Cells together1

• The epidermis is composed of multiple layers of flattened cells that overlie … Desmosomes connect two cells together. (conceptsmedias.com)

Regulation1

• Plakoglobin is a component of both the adherens junctions and desmosomes, and therefore plays a vital role in the regulation of cell-cell adhesion. (oncotarget.com)

Connect1

• Gap junctions connect the cytoplasms of neighboring cells electrically allowing cardiac action potentials to spread between cardiac cells by permitting the passage of ions between cells, producing depolarization of the heart muscle. (wikipedia.org)

Types of cell1

• The three types of cell junction recognised as making up an intercalated disc are desmosomes, fascia adherens junctions, and gap junctions. (wikipedia.org)

Include1

• Does the desmosome include the associated intermediate filaments? (geneontology.org)

Complex1

• Note that GO:0043296 "apical junction complex" is not part of 45177. (geneontology.org)

Plasma1

• They interact through their extracellular domains to hold theadjacent plasma membranes together.The importance of desmosome junctions is demonstrated by some forms of thepotentially fatal skin disease pemphigus. (ostatic.com)

Attach1

• In this way, muscle cells,for example, attach to their tendons at the myotendinous junction. (ostatic.com)

Animal1

• Neighboring animal cells are bridged via these junctions and desmosomes. (conceptsmedias.com)

Blue1

• the actin filaments represent the retrograde flow and the blue arrows indicate its characteristic centripetal flow. (mechanobio.info)

Region1

• Does the figure really show that armadillo is found in the apical region of the cell, or at apical junctions, which are not part of the apical region. (geneontology.org)