AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentHealth Care
AcromegalyHuman Growth HormoneGrowth Hormone-Secreting Pituitary AdenomaPituitary NeoplasmsOctreotideSomatostatinInsulin-Like Growth Factor IGigantismGrowth HormoneAdenomaBromocriptineAdenoma, AcidophilGrowth Hormone-Releasing HormoneThyrotropin-Releasing HormoneReceptors, SomatotropinErgolinesPeptides, CyclicAdenoma, ChromophobeProlactinomaPituitary GlandHyperprolactinemiaMacroglossiaSphenoid BoneHormonesHypercementosisFibrous Dysplasia, PolyostoticGlucose Tolerance TestHormone AntagonistsTreatment OutcomeHypophysectomyEndocrine Surgical Procedures
SymptomsPeople with acromegalyManagement of acromegalyEffective treatment for acromegalyHormonalSuccess rate of acromegalyClinicalPatientsOverproduction of growth hormoneComplicationsIndividuals with acromegalyDiagnosis and treatmentCause of acromegalyGigantism in childrenWoman with acromegalyPrognosisAdultsGlobal acromegalyTreat acromegalyDevelop acromegalySurgeryProgressionTumorsHyperthyroidismGrowthCushing'sOften diagnosedDiseaseChildhood2022Tumor of the pituitarLife expectancyPfizerAffectsGeneticRadiationDiagnosingGlucoseTherapiesBonesPegvisomantCarneyRareTherapyPituitary tumorPrimarilyNIDDKOctreotideSignificantly
Symptoms14
  • Explore the symptoms, diagnosis, treatment options and injection information. (pfizer.com)
  • Many acromegaly symptoms improve, and you can eventually sleep better and discontinue taking medications for diabetes and high blood pressure. (uvahealth.com)
  • Acromegaly is most often diagnosed in middle-aged adults, but symptoms can appear at any age. (nih.gov)
  • Symptoms of acromegaly can vary from person to person. (nih.gov)
  • The symptoms of acromegaly are mainly related to the effects of abnormally high production of GH and another hormone, IGF-1 (insulin growth factor-1), which is "controlled" by GH. (gilmorehealth.com)
  • Parlodel is sometimes used with surgery or radiation to treat acromegaly , and it is also used to treat symptoms of Parkinson's disease , such as stiffness, tremors, muscle spasms, and poor muscle control. (rxlist.com)
  • Symptoms of acromegaly include enlarged hands and feet, facial changes, joint pain, and thickened skin. (theindependentpharmacy.su)
  • The treatments primarily include surgery, medications, and radiotherapy, which can effectively reduce the symptoms and complications associated with the disorder. (topmaxify.com)
  • For instance, somatostatin analogues, used as first-line medical therapy for acromegaly, are also employed in the management of neuroendocrine tumours and symptoms of carcinoid syndrome. (topmaxify.com)
  • By doing so, individuals who suffer from acromegaly can improve their symptoms and reduce potential risks of complications. (livhospital.com)
  • Acromegaly symptoms develop gradually and can change from one person to another. (livhospital.com)
  • The treatment of acromegaly aims to normalize GH production, relieve symptoms, and reduce the risk of complications. (livhospital.com)
  • Acromegaly cannot be fully reversed, but early diagnosis and treatment can help control symptoms and prevent further progression of the condition. (livhospital.com)
  • We describe a 24-year-old Uzbek man who presented with many clinical symptoms and signs of apparent acromegaly. (medscape.com)
People with acromegaly3
  • People with acromegaly also have an increased risk for colon polyps , which may develop into colon cancer if not removed. (nih.gov)
  • Some people with acromegaly may have a genetic condition that can lead tumors to develop in different parts of their bodies. (nih.gov)
  • Compared with controls, people with acromegaly showed a significantly higher prevalence of vertebral fractures -- with many experiencing multiple and severe fractures. (medpagetoday.com)
Management of acromegaly4
Effective treatment for acromegaly1
Hormonal6
Success rate of acromegaly2
  • Improved surgical techniques, such as minimally invasive surgery and the development of novel drug therapies, have increased the success rate of acromegaly treatment, which in turn fuels market growth. (topmaxify.com)
  • The demand for non-surgical options and the popularity of pharmacological therapies for acromegaly treatment is increasing on a regular basis due to the low success rate of acromegaly surgeries. (technavio.com)
Clinical14
  • Acromegaly: an Endocrine Society Clinical Practice Guideline. (medscape.org)
  • The goal of this activity is to improve clinician recognition, screening, and diagnosis of acromegaly in their clinical practice. (medscape.org)
  • Echocardiography and sleep apnea testing are used to determine the clinical impact of acromegaly. (orpha.net)
  • Parlodel treatment is indicated in patients with prolactin-secreting adenomas , which may be the basic underlying endocrinopathy contributing to the above clinical presentations. (rxlist.com)
  • Information, news, resources and insights from the world's leading experts on specific pituitary conditions and treatments, including research and clinical trials. (pituitaryworldnews.org)
  • A clinical practice guideline from the American College of Physicians on treatment to prevent fractures in men and women with low bone density or osteoporosis includes six recommendations: two strong recommendations, based on high- or moderate-quality evidence, and four weak ones, based on low-quality evidence. (medscape.com)
  • Therapy should be individualized based on each patient's clinical scenario, with the risks and benefits of treatment discussed between the clinician and patient. (medscape.com)
  • Dermatitis herpetiformis: pathophysiology, clinical presentation, diagnosis and treatment * * Work performed at West Paraná State University (UNIOESTE) - Cascavel (PR), Brazil. (scielo.br)
  • The FDA placed a clinical hold on Vertex's investigational diabetes cell therapy VX-880 , saying the company didn't have enough evidence to support a treatment dose increase. (medpagetoday.com)
  • The other is located at Kennedy Krieger Institute in Baltimore, MD. The funding for this grant will go to help support projects, including a biomarker study that will aid in preparing for pre-clinical trial design as they move forward towards finding possible treatments for patients with SYNGAP1 mutations. (hcplive.com)
  • Ocular Monkeypox This report describes five patients who developed ocular monkeypox, highlighting its varying clinical manifestations and the importance of prompt evaluation and treatment to prevent complications. (medscape.com)
  • Efficacy of Lanreotide 120 mg Primary Therapy in Acromegaly Learn more about the clinical benefits of lanreotide as a primary treatment for patients with acromegaly. (medscape.com)
  • Acromegaly usually is suspected on clinical grounds. (medscape.com)
  • OBJECTIVE: The aim was to formulate clinical practice guidelines for acromegaly. (bvsalud.org)
Patients48
  • Acromegaly is rare, with only three or four patients per million individuals diagnosed with the condition each year. (pfizer.com)
  • This activity is intended for primary care clinicians, diabetologists & endocrinologists, orthopedists & orthopedic surgeons, nurses, and other healthcare professionals that care for patients with acromegaly. (medscape.org)
  • In patients with acromegaly, GH levels either do not suppress or increase. (uvahealth.com)
  • The aim of this study was to investigate the effects of a 6-month octreotide treatment on cardiac mass and function by means of Doppler echocardiography in 11 normotensive patients affected with active acromegaly. (unina.it)
  • In a separate analysis of 248 patients with sporadic acromegaly, a mutation in the GPR101 gene was found in about 4% of cases. (medscape.com)
  • The presentation of patients with gigantism is usually dramatic, unlike the insidious onset of acromegaly in adults. (medscape.com)
  • Besides disease control, patient's need represents a major target of medical treatment in chronic diseases such as acromegaly, in order to improve compliance to therapy and patients' quality of life. (unige.it)
  • This new oral treatment could be a God send for many acromegaly patients. (patientworthy.com)
  • Since Crinetics Pharmaceuticals projects to have CRN00808 in the clinic by the end of this year, we are all looking forward to seeing quick (positive) changes in patients' acromegaly progression, as well as their overall quality of life. (patientworthy.com)
  • Radiotherapy and medical treatment are important because in long-term studies, surgery has been found to cure only approximately 60% of patients with acromegaly. (medscape.com)
  • [ 24 ] Slow-release formulations of somatostatin are now widely used (including as a primary treatment) and appear to be safe and effective in 50-60% of the patients. (medscape.com)
  • Octreotide suppresses the serum GH level to less than 2.5 mcg/L in 65% of patients with acromegaly and normalizes circulating IGF-I levels in 70% of patients. (medscape.com)
  • Long-acting formulations, including long-acting octreotide, lanreotide, and pasireotide, have been demonstrated to produce consistent GH and IGF-I suppression in patients with acromegaly with once-monthly or biweekly intramuscular depot injections. (medscape.com)
  • In an open-label, parallel-group, dose-response study, which included 29 patients with acromegaly and 3 with pituitary gigantism, 5 injections of lanreotide Autogel were administered over a 24-week period, in dosages of 60, 90, or 120 mg. (medscape.com)
  • Many patients with acromegaly can lead a normal life after surgery. (theindependentpharmacy.su)
  • The present study is planned as an expanded treatment protocol to provide acromegalic patients for whom medical therapy is appropriate access to pasireotide LAR while regulatory approval for pasireotide is sought. (clinicaltrialsgps.com)
  • Patients with confirmed diagnosis of active acromegaly with elevated IGF-1 (>ULN) and random GH (>1 μg/L) within 30 days of screening. (clinicaltrialsgps.com)
  • A 2009 study indicated that the use of a case manager for the treatment of patients with hip fractures can lead to more frequent use of appropriate osteoporosis treatment and may result in fewer fractures, increased life expectancy, and significant health-care cost savings. (medscape.com)
  • These efforts are paving the way for the discovery of novel treatment methods that can significantly enhance the quality of life for acromegaly patients, thereby providing a positive outlook for the global acromegaly treatment market. (topmaxify.com)
  • Treatment of acromegaly patients with risk-adapted single or fractionated stereotactic high-precision radiotherapy: High local control and low toxicity in a pooled series. (qxmd.com)
  • The purpose of this work was to evaluate a prospectively initiated two-center protocol of risk-adapted stereotactic radiosurgery (SRS) or stereotactic radiotherapy (SRT) in patients with acromegaly. (qxmd.com)
  • The objective of this study was to examine acromegaly treatment outcomes during long-term care at a specialized pituitary center in patients presenting with lack of biochemical control. (biomedcentral.com)
  • Acromegaly patients included in this study were those who presented biochemically-uncontrolled for care at the center. (biomedcentral.com)
  • Of the 40 patients without prior treatment, 82.5% achieved control by study end. (biomedcentral.com)
  • This observational study shows that treatment outcomes of biochemically-uncontrolled acromegaly patients improve with directed care, particularly for those that initially present untreated. (biomedcentral.com)
  • Patients often require multiple modalities of treatment, many of which are offered with the highest quality at specialized pituitary centers. (biomedcentral.com)
  • Despite specialized care, some patients were not able to achieve biochemical control with methods of treatment that were available at the time of their treatment, showing the need for additional treatment options. (biomedcentral.com)
  • The objective of this study was to report treatment patterns and outcomes of acromegaly patients that presented biochemically-uncontrolled for care at a single US pituitary center, based on data from a US acromegaly registry. (biomedcentral.com)
  • SOMAVERT is a medicine used to treat patients who have acromegaly. (indianpharmanetwork.co.in)
  • Treatment with novel diazoxide choline extended-release tablets significantly improved hyperphagia in patients with Prader-Willi syndrome, Soleno Therapeutics announced. (medpagetoday.com)
  • the long-term treatment of acromegalic patients who have had an inadequate response to or cannot be treated with surgery and/or radiotherapy. (guidelinecentral.com)
  • the treatment of adult patients with unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs) to improve progression-free survival. (guidelinecentral.com)
  • SOMATULINE DEPOT is indicated for the long-term treatment of acromegalic patients who have had an inadequate response to surgery and/or radiotherapy, or for whom surgery and/or radiotherapy is not an option. (guidelinecentral.com)
  • See full prescribing information for dosage adjustment in patients with acromegaly and renal or hepatic impairment. (guidelinecentral.com)
  • Treatment takes just one session, and patients can return to normal activities almost immediately. (wakehealth.edu)
  • Eight patients had refractory acromegaly despite maximal conventional treatments: all had undergone conventional radiotherapy (CRT), mean interval between CRT and GK 15.6 years. (endocrine-abstracts.org)
  • Wherever feasible, curative surgical excision is the treatment of choice.Materials and Methods: Twenty four consecutive patients with pancreatic NETs were referred for consideration of surgery over a six-year period (1999 2005). (endocrine-abstracts.org)
  • 84 patients were considered euthyroid before GH treatment and 159 patients had central hypothyroidism an. (endocrine-abstracts.org)
  • we enrolled 91 acromegaly patients during. (endocrine-abstracts.org)
  • Introduction: First-generation SRL (fg-SRL) represent the treatment of choice in acromegaly patients with post-neurosurgical adenomatous remnant and GH-hypersecretion. (endocrine-abstracts.org)
  • We're committed to doing everything we can to help to educate and raise awareness for this rare disease and ultimately help patients in need of treatment," a representative from Pfizer told Rare Disease Report ® . (hcplive.com)
  • Tafamidis, our investigational oral therapy for this condition, remains the only potential treatment that has been evaluated in a Phase 3 trial designed to assess the safety and efficacy, specifically in patients with ATTR-CM. (hcplive.com)
  • NEWTON, Mass., Jan. 08, 2016 (GLOBE NEWSWIRE) -- Chiasma, Inc. (NASDAQ:CHMA), a late-stage biopharmaceutical company developing Mycapssa™ (octreotide) capsules, an investigational oral drug for the maintenance therapy of adult patients with the orphan disease acromegaly, today reviewed its key accomplishments for 2015 and provided an update on its core objectives and expected milestones for 2016. (biospace.com)
  • Advanced Lead Product Candidate Toward Potential Approval - In June 2015, Chiasma submitted an NDA with the FDA seeking approval for the marketing and sale of Mycapssa™ for the potential maintenance therapy of adult patients with acromegaly. (biospace.com)
  • Treatment of Metastatic Uveal Melanoma in 2022 Recent developments in our understanding of metastatic uveal melanoma and treatment advancements have improved the prognosis of these patients. (medscape.com)
  • During February 2012, the Referral Abroad Department (RAD) of the Palestinian Ministry of Health (MoH) referred 1,190 patients to health facilities for specialized treatment not available in MoH facilities in Gaza (15% fewer than during January). (who.int)
  • All the 10 denied patients had been referred for orthopedic treatment. (who.int)
  • acromegaly) patients. (bvsalud.org)
Overproduction of growth hormone1
  • In the vast majority of cases (over 95%), overproduction of growth hormone, which causes acromegaly, is associated with the development of a benign pituitary tumor (pituitary adenoma), a small gland (about the size of a pea) located at the bottom of the brain, just above the nose. (gilmorehealth.com)
Complications9
  • Early recognition and appropriate treatment are crucial for reducing the potentially debilitating complications of the disease. (bmj.com)
  • What are the complications of acromegaly? (nih.gov)
  • The problem is, if acromegaly isn't treated quickly and effectively, it can cause serious complications that are even life-threatening. (patientworthy.com)
  • It's important to get an accurate diagnosis as early as possible because untreated acromegaly can lead to severe health complications. (theindependentpharmacy.su)
  • Post-surgery care also includes managing any complications or side effects, and providing support for any emotional or psychological issues that may arise from the condition or its treatment. (theindependentpharmacy.su)
  • Furthermore, the growing awareness of the disease and its complications, enhanced by health education programs, has led to an increase in early diagnosis and treatment. (topmaxify.com)
  • Unless being treated properly for a long time, acromegaly can lead to serious health problems and complications. (livhospital.com)
  • Early diagnosis and appropriate treatment can help prevent or minimize these complications. (livhospital.com)
  • As mentioned above, without proper management and treatments, acromegaly can lead to severe complications and an increased risk of mortality. (livhospital.com)
Individuals with acromegaly2
  • They are targeted at individuals with acromegaly who are inadequately treated with the combination therapy of lanreotide autogel and pegvisomant by Ipsen and somatostatin analogs. (technavio.com)
  • However, with timely intervention and appropriate treatment, the prognosis for individuals with acromegaly can be significantly improved, reducing the risk of fatality. (livhospital.com)
Diagnosis and treatment4
  • Zahr R, Fleseriu M. Updates in diagnosis and treatment of acromegaly. (medscape.org)
  • Guidelines for the diagnosis and treatment of dermatitis herpetiformis. (scielo.br)
  • Please consult your physician for diagnosis and treatment. (livhospital.com)
  • OBJECTIVE: The aim of this guideline was to formulate practice guidelines for the diagnosis and treatment of Paget's disease of the bone. (bvsalud.org)
Cause of acromegaly2
Gigantism in children2
Woman with acromegaly2
  • A 66-year-old woman with acromegaly and diabetes mellitus as well as primary hyperthyroidism is described. (nel.edu)
  • A woman with acromegaly can produce breast milk even if she is not breastfeeding. (msdmanuals.com)
Prognosis2
  • What is the prognosis for acromegaly? (barrowneuro.org)
  • The prognosis for acromegaly depends on whether surgery can completely remove the tumor and whether medications can induce remission if surgery is not completely successful in removing all the tumor. (barrowneuro.org)
Adults9
  • After puberty, bones lose their ability to grow and therefore, adults don't grow tall when they develop acromegaly. (uvahealth.com)
  • In young adults, acromegaly has been linked to defects in certain genes. (nih.gov)
  • Acromegaly is most commonly caused by a noncancerous tumor of the pituitary gland in adults. (barrowneuro.org)
  • Acromegaly occurs in adults after the bones have finished growing during puberty. (barrowneuro.org)
  • Adults with acromegaly have thicker than normal bones and enlarged hands, feet, and facial features. (medlineplus.gov)
  • In adults, it is called acromegaly. (msdmanuals.com)
  • Increased growth hormone in adults thus cannot increase the length of bones, but it does cause acromegaly, in which the bones become deformed rather than elongated. (msdmanuals.com)
  • Obtain U.S. Approval and Successfully Launch Mycapssa ™ - Chiasma is focused on obtaining FDA approval of Mycapssa™ for the potential maintenance treatment of adults with acromegaly, with a PDUFA date of April 15, 2016. (biospace.com)
  • It aims to improve the quality of life for adults with multiple sclerosis by promoting symptom management, comprehensive reviews and effective relapse treatment. (bvsalud.org)
Global acromegaly3
  • According to the report by Expert Market Research (EMR), the global Acromegaly Treatment Market Share reached a value of USD 1.61 billion in 2022. (topmaxify.com)
  • The EMR report looks into the market shares, plant turnarounds, capacities, investments, and acquisitions and mergers, among other major developments, of the global acromegaly treatment companies. (topmaxify.com)
  • The Americas has always been a key market in the context of global acromegaly and gigantism drugs demand and this is mainly due to the high prevalence of the disease in the region. (technavio.com)
Treat acromegaly2
Develop acromegaly1
Surgery13
  • In most cases, removing the tumor through surgery is the preferred treatment. (uvahealth.com)
  • Treatment options include surgery to remove the tumor, medications, and radiation therapy. (wikipedia.org)
  • Surgery is the only curative treatment, while medical therapies are administered life-long. (unige.it)
  • For pituitary adenomas, transsphenoidal surgery is usually considered the first line of treatment, followed by medical therapy for residual disease. (medscape.com)
  • Somatostatin and dopamine analogues and GH receptor antagonists are the mainstays of medical treatment for GH excess and are generally used when primary surgery fails to induce complete remission. (medscape.com)
  • Yes, acromegaly can often be cured with surgery as it is most commonly caused by a noncancerous tumor of the pituitary gland. (barrowneuro.org)
  • Surgery is the best form of treatment and the only way to achieve a cure. (barrowneuro.org)
  • When medication isn't enough to control acromegaly, surgery is often the next step. (theindependentpharmacy.su)
  • The most common surgical procedure for acromegaly is transsphenoidal surgery, which involves removing the tumor through the nose and sinuses. (theindependentpharmacy.su)
  • It is primarily used if the pituitary gland tumor causing the acromegaly cannot be controlled with surgery or radiation, and the use of somatostatin analogues is unsuccessful, but is also effective as a monotherapy. (indianpharmanetwork.co.in)
  • Treatment for the tumor may include radiation therapy , surgery, and/or medicine. (medlineplus.gov)
  • A three-week treatment with octreotide prior to surgery led to slight visual improvement and CT scan showed some new necrotic areas within the tumor mass. (nih.gov)
  • Lateral view of a skull radiograph is routinely used during the orthodontic treatment and maxillofacial surgery. (bvsalud.org)
Progression1
  • Due to its insidious onset and slow progression, acromegaly is often diagnosed from four to more than ten years after its onset, and is most often diagnosed in middle age (average age 40-50 years). (orpha.net)
Tumors4
  • Gamma Knife is a type of radiation treatment used commonly to treat brain tumors and other abnormal conditions of the head. (wakehealth.edu)
  • These tumors stimulate the pituitary gland to produce an excess of GH, leading to the development of acromegaly. (livhospital.com)
  • Eventhough it is not hereditary, certain gene mutations may increase the risk of developing pituitary tumors, which can lead to acromegaly. (livhospital.com)
  • Pituitary tumors may either be clinically silent or secrete hormones, including prolactin, growth hormone (acromegaly), adrenocorticotrophic hormone (Cushing's disease) or, rarely, thyroid-stimulating hormone or gonadotropins. (bvsalud.org)
Hyperthyroidism2
  • Acromegaly and diabetes mellitus associated with hyperthyroidism. (nel.edu)
  • A 41-year-old male presented with progressive visual defects, acromegaly and hyperthyroidism. (nih.gov)
Growth30
Cushing's2
  • The RVC team was the first in the UK to treat cats with acromegaly (hypersomatotropism) and is now also routinely performing hypophysectomy in dogs (and the occasional cat) with pituitary-dependent Cushing's syndrome (hyperadrenocorticism). (rvc.ac.uk)
  • Hypophysectomy is an excellent treatment option for pituitary dependent Cushing's syndrome. (rvc.ac.uk)
Often diagnosed1
  • In acromegaly, a severe disease that is often diagnosed late, morbidity and mortality rates are high, particularly as a result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. (medscape.com)
Disease6
  • Acromegaly is a chronic, progressive, multisystemic disease associated with significant morbidity and increased mortality. (bmj.com)
  • Treatment is aimed at correcting (or preventing) tumor compression by excising the disease-causing lesion, and at reducing GH and IGF-I levels to normal values. (orpha.net)
  • The results of this study show an improvement in cardiac structural and functional abnormalities during chronic treatment with octreotide, thus supporting the hypothesis of a specific heart disease secondary to high circulating GH levels. (unina.it)
  • Criteria for disease control in acromegaly under SSA treatment: mean GH profile or GH random? (endocrine-abstracts.org)
  • The disease control is, in turn, associated with lower mortality and therefore to verify the optimal control of the disease activity is of critical importance to adapt the dose and the choice of alternative treatment. (endocrine-abstracts.org)
  • ATTR-CM is a rare, progressive and universally fatal disease associated with progressive heart failure, and for which there are no approved pharmacologic treatments. (hcplive.com)
Childhood1
  • The gene aryl hydrocarbon receptor interacting protein, AIP (11q13.3), has been identified as a major susceptibility factor, particularly when acromegaly begins in childhood or adolescence. (orpha.net)
20221
  • EMAILWIRE.COM, April 14, 2022 ) Cushings Syndrome And Acromegaly Treatment Market 2022 Cushings Syndrome And Acromegaly Treatment Industry is bound at a CAGR of 9.3% between 2018-2026. (emailwire.com)
Tumor of the pituitar1
Life expectancy2
  • 1 Failure to receive adequate medical treatment for this condition can reduce life expectancy by 10 years. (pfizer.com)
  • with treatment, life expectancy is not reduced. (wikipedia.org)
Pfizer1
Affects1
Genetic3
Radiation2
  • [ 5 ] Radiation treatment usually is reserved for recalcitrant cases. (medscape.com)
  • The frame helps surgeons pinpoint the exact treatment location and holds the patient's head still as radiation is delivered. (wakehealth.edu)
Diagnosing2
Glucose1
Therapies1
  • Advances in Drug Therapy and Delivery for Cataract Treatment Recent advancements have led to potential new cataract therapies and improved delivery methods. (medscape.com)
Bones1
  • By definition, acromegaly can only occur after your bones and other organs have stopped growing, usually around 18 years for women and slightly older for men. (barrowneuro.org)
Pegvisomant1
  • Brand Name "SOMAVERT (pegvisomant) for injection" can be imported and made available on "Patient Name basis" treatment in India. (indianpharmanetwork.co.in)
Carney1
  • Differential diagnosis includes other causes of acromegaly (FIPA, MEN1, Carney complex and XLAG) as well as pachydermoperiostosis and acromegaloid features of severe insulin resistance. (orpha.net)
Rare3
Therapy3
  • Expert opinion: The constant progresses in the medical treatment of acromegaly could lead to an individualized therapy based on tumor, as well as patient's characteristics. (unige.it)
  • Current acromegaly treatments often involve painful deep intramuscular injections of therapy that must be administered monthly. (patientworthy.com)
  • Our findings suggest that, cabergoline can be used as a first-line therapy in giant prolactinomas because tumoral shrinkage without a surgical procedure and rapid improvement in visual field defect is achieved with this medical treatment. (nel.edu)
Pituitary tumor1
  • The surgical removal of the pituitary tumor causing excess GH production is often the first-line treatment. (livhospital.com)
Primarily1
NIDDK1
  • That's why the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which is part of the National Institutes of Health (NIH) gave this jackpot of money for new treatment. (patientworthy.com)
Octreotide3
Significantly2
  • The expanding applications of various acromegaly treatments in the pharmaceutical industry are significantly accelerating the acromegaly treatment market development globally. (topmaxify.com)
  • Oestrogen treatment significantly enhanced expression of Nppa, Nppc, Npr1, and Npr2 in GH3 somatolactotropes, but inhibited CNP-stimulated cGMP accumulation. (bvsalud.org)