Acridone. Medical search. Frequent questions

Rutaceae) used traditionally by Akamba tribe in Kenya yielded three acridone alkaloids, a furoquinoline alkaloid and two triterpenoids. (academicjournals.org)
Acridone alkaloids as potent inhibitors of cathepsin V. (nih.gov)
Chemical studies on this genus have led to the isolation of an extensive array of coumarins and alkaloids (including acridones, carbazoles, furoquinolines, and indoles) [16] . (jse.ac.cn)

This experimental data suggests that hybrid systems of acridone with substituted pyrimidines can be taken as a lead for the design of efficient inhibitors and active compounds which can be taken up for further studies. (researcher-app.com)

Techasakul, S. Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies of 2,N10-Substituted Acridones as DNA-Intercalating Agents. (cri.or.th)

Acridone constitutes the scaffold of some synthetic compounds with diverse pharmacological activities. (wikipedia.org)
Compounds based on acridone, which have three linear rings, with the center ring containing a ring nitrogen and a keto oxygen opposite to each other. (bvsalud.org)

Introduction of a fluorine atom into the acridone cycle results in an increase of the fluorescence quantum yield and decay time whereas immobilization in a rigid polymer matrix (polystyrene) further extends the lifetime up to 18 ns. (advion.com)
His study looks at the intersection of Biophysics and topics like Förster resonance energy transfer with Acridone, Carbon chemistry, Dual fluorescence and Drug resistance. (research.com)

3-Chloro-6-(2-diethylamino-ethoxy)-10-(2-diethylamino-ethyl)-acridone has shown promise as an antimalarial drug. (wikipedia.org)
What they did with that is engineered the Acridone ring system to have its own antimalarial activity. (chemistryworld.com)

Acridone is an organic compound based on the acridine skeleton, with a carbonyl group at the 9 position. (wikipedia.org)
Acridine containing functionalities can degrade to acridone by means of a hydrolysis reaction. (rug.nl)

Multi spectroscopic and molecular simulation studies of propyl acridone binding to calf thymus DNA in the presence of electromagnetic force [med. (emf-portal.org)

Hybrid systems of acridones with substituted pyrimidines were designed with an objective of discovering next generation anticancer agents targeting multiple mechanisms in the cancer cell. (researcher-app.com)

Thermal dimerization of the acridone alkaloid noracronycine ( 2 ) leads to Diels-Alder adducts ( 3 ) and ( 4 ), possessing a rearranged structure. (heterocycles.jp)

A prominent example is the xanthone family of dyes (xanthone, thioxanthone, acridone) where the ICS rate constants and triplet quantum yields are strongly solvent dependent. (hhu.de)

We compared AOX activity in rhesus monkeys, guinea pigs, and humans using phthalazine and N -[2-(dimethylamino)ethyl]acridone-4-carboxamide (DACA) as substrates and raloxifene as an inhibitor. (aspetjournals.org)
A simple and sensitive method for the determination of free fatty acids (FFAs) using acridone ́ 9 ́ ethyl ́ p ́ toluenesulfonate (AETS) as a fluorescence derivatization reagent by high performance liquid chromatography (HPLC) has been developed. (virginia.edu)

15. A new acridone with antifungal properties against Candida spp. (nih.gov)

ISC rate constamts of acridone in vacuum (left) and acetonitrile solution (right). (hhu.de)

Pyranoquinoline with n-alkyl substitution at the 3-position leads to the formation of pyrrolo-acridones via [3 + 2] annulations/ring opening and successive intramolecular cross-aldol condensation. (unboundmedicine.com)