Aclarubicm is an anthracycline antibiotic with antineoplastic actions similar to those of the other anthracyclines (see Doxorubicin Hydrochloride), although it inhibits RNA synthesis more strongly than DNA synthesis. (pocketdrugguide.com)
It has been used as the hydrochloride in the treatment of malignant blood disorders, such as acute myeloid leukaemia. (pocketdrugguide.com)
2. Decitabine in combination with G-CSF, low-dose cytarabine and aclarubicin is as effective as standard dose chemotherapy in the induction treatment for patients aged from 55 to 69 years old with newly diagnosed acute myeloid leukemia. (nih.gov)
5. Clinical efficacy of decitabine in combination with standard-dose cytarabine, aclarubicin hydrochloride, and granulocyte colony-stimulating factor in the treatment of young patients with newly diagnosed acute myeloid leukemia. (nih.gov)