• 1. Sharief FS, Lee H, Leuderman MM, Lundwall A, Deaven LL, Lee CL, Li SS (1989) Human prostatic acid phosphatase: cDNA cloning, gene mapping and protein sequence homology with lysosomal acid phosphatase. (nordicmubio.com)
  • 2. Veeramani S, Yuan TC, Chen SJ, Lin FF, Petersen JE, Shaheduzzaman S, Srivastava S, MacDonald RG, Lin MF (2005) Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer. (nordicmubio.com)
  • 3. Graddis TJ, McMahan CJ, Tamman J, Page KJ, Trager JB (2011) Prostatic acid phosphatase expression in human tissues. (nordicmubio.com)
  • Tartrate-resistant acid phosphatase (TRAP or TRAPase), also called acid phosphatase 5, tartrate resistant (ACP5), is a glycosylated monomeric metalloprotein enzyme expressed in mammals. (wikipedia.org)
  • This gene provides instructions for making an enzyme called tartrate-resistant acid phosphatase type 5 (TRAP). (medlineplus.gov)
  • We prepared root-surrounding tissues with (R) or without (N) physiological root resorption scraped off at three regions (R1-R3 or N1-N3) from the cervical area to the apical area of the tooth and measured both TGF-β and the tartrate-resistant acid phosphatase (TRAP) activities. (preprints.org)
  • The purpose of this study was to investigate the activities of the total acid phosphatase (TAP), tartrate-resistant acid phosphatase (TRAP), low molecular weight protein tyrosine phosphatase (LMW-PTP) and alkaline phosphatase (ALP) enzymes, as well as the possible correlation in the serum and in unstimulated whole saliva of children. (bvsalud.org)
  • Lysosomal enzyme activities did not change in the liver tissue. (portlandpress.com)
  • The activity of hepatic drug-metabolizing enzymes in post-mitochondrial fraction and the cytochrome P 450 contents in microsomal fraction decreased significantly, while lysosomal enzymes such as acid phosphatase, acid ribonuclease and cathepsin B showed an increase in the liver homogenates of infected animals. (ias.ac.in)
  • Effect of induced oxidative stress and herbal extracts on acid phosphatase activity in lysosomal and microsomal fractions of midgut tissue of the silkworm, Bombyx mori. (lookformedical.com)
  • and (3) biochemical evidence of increased lysosomal fragility precedes anatomical evidence of enzyme translocation in the tissue. (elsevierpure.com)
  • Although alkaline phosphatases are present in different body tissues and have different physiochemical properties, they are true isoenzymes because they catalyze the same reaction. (statpearls.com)
  • Even though alkaline phosphatases are present in many tissues throughout the body, their precise physiological function remains largely unknown. (statpearls.com)
  • Alkaline phosphatases are classified as tissue-specific and tissue-nonspecific types. (statpearls.com)
  • Alkaline phosphatases found in the intestine, placenta, and germinal tissue are tissue-specific. (statpearls.com)
  • The human alkaline phosphatases (hALP) are found anchored on the cell membrane by glycosylphosphatidylinositol. (statpearls.com)
  • In the present study, glucose, acid and alkaline phosphatases (ACP and ALP), α-amylase and lipase were measured for the first time in tissue homogenates of Biomphalaria arabica snails, molluscan intermediate host for Schistosoma mansoni in Saudi Arabia. (scialert.net)
  • 2005). Carbohydrate metabolizing enzymes (e.g., α-amylase), lipid degrading enzymes (e.g., lipase) and phosphatases (acid and alkaline phosphatases) were recorded among target enzymes which should be disturbed and may provide more accurate information on the molluscicide-induced stress on molluscs. (scialert.net)
  • Transcribed from this gene is a 1.5kb mRNA with an open reading frame (ORF) of 969-975 bp encoding a 323-325 amino acid protein. (wikipedia.org)
  • In the rat, the ORF is 981 bp in length and encodes for a 327-amino acid protein. (wikipedia.org)
  • These genes comprise 289 Transcription Factors (TFs) representing Basic Helix-loop Helix (bHLH), Ethylene Response Factors (ERFs), myeloblastosis (MYB), No apical meristem (NAC), and WRKY amino acid motif (WRKY) type major families known to be involved in the mechanism of stress tolerance. (frontiersin.org)
  • 5. Liver catalase and d-amino acid oxidase activities showed a slight increase at 1 day post-ligation but a significant fall by 8 days. (portlandpress.com)
  • the addition altered the levels of marker differential metabolites in broiler breast muscle through amino acid metabolic pathways, lipid metabolic pathways, and energy metabolic pathways, thereby protecting breast muscle from AFB1-induced meat loss, oxidative stress, and inflammatory response. (poultrydvm.com)
  • It is differentiated from other mammalian acid phosphatases by its resistance to inhibition by tartrate and by its molecular weight. (wikipedia.org)
  • 6. Lactate dehydrogenase, a cytosol enzyme, showed a decrease in activity after 1 day but an increase in tissue activities 8 days after ligation. (portlandpress.com)
  • Biochemical studies were performed on alkaline phosphatase, acid phosphatase, lactate dehydrogenase, and glucose-6-phosphate dehydrogenase activity levels. (ac.ir)
  • Protein phosphatases reverse the covalent modifications of numerous cellular proteins imposed by the activation of protein kinases and, therefore, play key role in cell signaling metabolism, growth and differentiation. (bvsalud.org)
  • Protein kinase C (PKC) is routinely assayed, after it is partially purified over DEAE-cellulose chromatography to eliminate any interfering protein kinases and phosphatases, by measuring the transfer of γ-phosphate of [γ- 32 P]ATP to Hl histone. (uky.edu)
  • We report here that once MBP 4-14 is phosphorylated, it is not dephosphorylated by okadaic acid-sensitive phosphatases (protein phosphatases 1, 2A and 3) or other protein phosphatases such as calcineurin and/or PP 2C present in hippocampal homogenates. (uky.edu)
  • Farrar, YJK, Vanaman, TC & Slevin, JT 1991, ' A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extracts ', Biochemical and Biophysical Research Communications , vol. 180, no. 2, pp. 694-701. (uky.edu)
  • YF viral antigens were found by immunohistochemistry (IHC) and YF virus-specific nucleic acids by polymerase chain reaction. (cdc.gov)
  • Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca(2+)-permeable Cationic Channel in lung carcinoma cells. (nih.gov)
  • Pathology of the tissue biopsy demonstrated proliferation of macrophages or dendritic cells, and positive staining with CD1a confirmed a diagnosis of Langerhans' cell histiocytosis (See Figure 2) . (reviewofophthalmology.com)
  • Microscopic review of the tissue specimen revealed proliferation of histiocytes (left) with positive CD1a staining, a marker for Langerhans' cells (right). (reviewofophthalmology.com)
  • Levels of lipid peroxides in rat caecum, blood, liver and kidney and the capacity of tissue homogenates to form lipid peroxides in vitro was enhanced after caecal amoebiasis in rats produced by Entamoeba histolytica (IB-1). (ias.ac.in)
  • In the liver and in other tissues, seladelpar also drives lipid metabolism resulting in reductions in LDL-cholesterol and fatty acids. (outsourcing-pharma.com)
  • 2. The microsomal enzymes in liver tissue showed complex changes. (portlandpress.com)
  • Total activities of cathepsin D, N-acetyl-β,D-glucosaminidase, and acid phoshphatase in ischemic tissue were not altered over the ensuing 2-hour period, but significant changes developed in the distribution of the enzymes between sedimentable (particle-bound) and nonsedimentable (soluble) fractions of the tissue homogenate. (elsevierpure.com)
  • Lung tissue macrophages showed dose-dependent increases in acid phosphatase staining density and carbon particles. (cdc.gov)
  • UCDA is a naturally-occurring bile acid that increases bile acid flow and promotes secretion of bile acids. (outsourcing-pharma.com)
  • Unlike cathepsin D and glucosaminidase, changes in acid phosphatase were maximal by 45 minutes, after which further increases in nonsedimentable activity were not apparent. (elsevierpure.com)
  • Ancient Amazon soils are characterised by low concentrations of soil phosphorus (P). Therefore, it is hypothesised that plants may invest a substantial proportion of their resources belowground to adjust their P-uptake strategies, including root morphological, physiological (phosphatase enzyme activities) and biotic (arbuscular mycorrhizal (AM) associations) adaptations. (springer.com)
  • Specifically, we expected that plants which invest in finer roots, and therefore have greater ability to explore large soil volumes, would have a high investment in physiological adaptations such as enhanced phosphatase production. (springer.com)
  • [3] This means they are found only in the tissues where they are expressed in physiological conditions. (statpearls.com)
  • The present study was performed to examine that transforming growth factor beta (TGF-β) in root-surrounding tissues on deciduous teeth during the physiological root resorption regulates the differentiation induction into odontoclast. (preprints.org)
  • Our findings suggest that TGF-β is closely related to the regulation of OPG induction and RANKL-mediated odontoclast differentiation depending on the timing of RANKL and OPG mRNA expression in the root-surrounding tissues of deciduous teeth during physiological root resorption. (preprints.org)
  • Glucose 6-phosphatase activity and ribonucleic acid, which are localized predominantly in the rough endoplasmic reticulum, were increased. (portlandpress.com)
  • Therefore, MBP 4-14 can be used for PKC assay in crude extracts of neural tissue. (uky.edu)
  • Nonsedimentable cathepsin D activity was significantly elevated in ischemic tissue by 15 minutes after occlusion and increased over the next 105 minutes. (elsevierpure.com)
  • Immunohistochemical staining of cathepsin D in ischemic tissue sections revealed apparent diffusion of the enzyme from discrete organelles into the surrounding cytosol by 30 minutes after occlusion, but not at 15 minutes. (elsevierpure.com)
  • We measured fine root diameter, specific root length (SRL), specific root area (SRA), root tissue density (RTD), root phosphatase activity (APase) and arbuscular mycorrhizal (AM) fungi colonisation. (springer.com)
  • Protected the bone tissue and prevented bone density from decreasing in the legs of hens on low-calcium diets. (poultrydvm.com)
  • Additionally, it provides attenuation maps which can be related to mineral density variations within calcified tissues [11]. (chestervetclinic.com)
  • Organomegaly, connective-tissue and ocular pathology, and central nervous system dysfunction may result. (medscape.com)
  • Beneath this layer lies connective tissue, which is made up of a dense network of elastic fibers and blood vessels. (icloudhospital.com)
  • We measured the concentrations of 18 analytes in thyroid cyst fluid specimens from benign (n = 17) and malignant (n = 3) lesions and in homogenates of normal thyroid tissue (n = 5). (avmi.net)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Although PDL and bone are two dissimilar tissues in physical and chemical properties, the continuity formed by blood vessels enables a flow of nutrients and maintains cellular activity responsible for PDL turnover and bone remodeling. (chestervetclinic.com)
  • Osteoclasts are specialized cells that break down and remove (resorb) bone tissue that is no longer needed. (medlineplus.gov)
  • These cells are involved in bone remodeling, which is a normal process that replaces old bone tissue with new bone. (medlineplus.gov)
  • Both types may grow and compress healthy bone tissue and absorb or replace it with abnormal tissue. (ucsfbenioffchildrens.org)
  • Improved microstructure of bone tissue. (poultrydvm.com)
  • Based on the root enzyme activity analyses, overexpression of any of the two genes could lead to increase in acid phosphatase activities. (isaaa.org)
  • Ongoing biomineralization could be analyzed using fluorochrome labeling on tissue sections from block specimens and attenuation profiles on virtual sections from tomography images. (chestervetclinic.com)
  • This protocol is amenable not only for detection and quantification purposes but also to study the expression of markers of numerous biological processes or tissue-specificity. (oncotarget.com)
  • Other biochemical markers, however, indicated colloidlike features and/or an admixture of thyroid tissue components to the cyst fluid. (avmi.net)
  • Many affected individuals have malfunctioning immune systems that attack the body's own tissues and organs, which is known as an autoimmune reaction. (medlineplus.gov)
  • Micro X-ray imaging is one such popular method as it provides a three- dimensional (3D) representation of organs and tissues. (chestervetclinic.com)
  • Tissue sections were prepared for histological studies using Haematoxylin and Eosin stains. (ac.ir)
  • Numerous studies in the field of mineralized tissues related to dental research have used the rat periodontium as a model to investigate adaptation of bone, PDL and root by applying many perturbations, predominantly disease [9] and extraneous loads [10]. (chestervetclinic.com)
  • The total phosphate concentration of leaf tissues of the high-expressing transgenic lines was also significantly higher than the control plants. (isaaa.org)
  • The earlier definition of advanced disease (bone metastasis and soft-tissue involvement) has also been improved. (medscape.com)
  • Radiographical evaluation showed an epiphyseal, osteolytic, and well-defined lesion with cortical break over the medial femoral condyle and soft-tissue extension into the medial patellar recess abutting the medial patellar retinaculum. (jbstjournal.com)
  • Imaging with both CT and MRI allows for enhanced characterization of both the bony changes and soft tissue extension into the orbit and cranial fossae. (reviewofophthalmology.com)
  • CymaBay announced recently the initiation of its 52-week, placebo-controlled, randomized, phase 3 study - 'Intended to Determine the Effects of seladelpar on normalization of Alkaline phosphatase (ALP) Levels in subjects with Primary Biliary Cholangitis (PBC)' known as IDEAL. (outsourcing-pharma.com)
  • A new technique has been presented that results in an acceleration of delayed primary healing with full thickness skin and subcutaneous tissue coverage. (who.int)
  • In this study, GLI1 expression in the synovial tissue of RA patients was positively correlated with RA-related scores and was highly expressed in collagen-induced arthritis (CIA) mouse articular macrophage-like cells. (elifesciences.org)
  • Acid phosphatase is a hydrolytic enzyme secreted by various cells, and it has five isoenzymes. (5minuteconsult.com)
  • 6 ] Osteoclasts are large multinucleated cells (MNCs) that remove the old/weakened bones by acid decalcification and proteolytic degradation. (e-jbm.org)
  • Tissues and Cells. (lu.se)
  • Except for the CK group, the rats in other groups were given 70 mg/kg retinoic acid to build the OP rat model, and the rats in the CK group were given the same amount of normal saline. (alljournal.net.cn)
  • Additional skeletal problems occur because of abnormalities of the tough, flexible tissue called cartilage that makes up much of the skeleton during early development. (medlineplus.gov)
  • Once the diagnosis is established by tissue biopsy, systemic evaluation is necessary for proper staging of the disease. (reviewofophthalmology.com)
  • In this study we present an overview of commonly used imaging methods to investigate calcified tissues and the PDL while addressing the plausible artifacts during specimen preparation, imaging and post processing of experimental data. (chestervetclinic.com)
  • 1993. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. (cdc.gov)
  • Relating in vitro to in vivo exposures with physiologically-based tissue dosimetry and tissue response models. (cdc.gov)
  • Histopathology, IHC studies, nucleic acid testing, and serology all demonstrated that the traveler died of YF complicated by angioinvasive aspergillosis. (cdc.gov)