Acetyltransferase acetyl coa and acyl carrier. Medical search. Frequent questions

protein_coding" "AAC74323","adhE","Escherichia coli","fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase [Ensembl]. (ntu.edu.sg)
Glutaryl-CoA degradation ( link ) involves glutaryl-CoA dehydrogenase (decarboxylating) to crotonyl-CoA (trans-but-2-enoyl-CoA), hydration to (S)-hydroxybutanoyl-CoA, oxidization to acetoacetyl-CoA, and cleavage by a C-acetyltransferase to two acetyl-CoA. (lbl.gov)

FabH performs an acyltransferase reaction with acetyl-CoA to generate an acetyl-S-FabH acyl-enzyme intermediate and subsequent decarboxylative Claisen-condensation with a malonyl-thioester carried by an acyl carrier protein (ACP). (bvsalud.org)

The systematic name of this enzyme class is acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase. (wikipedia.org)
Other names in common use include acetyl coenzyme A-acyl-carrier-protein transacylase, Acetyl CoA:ACP transacylase, [acyl-carrier-protein]acetyltransferase, [ACP]acetyltransferase, and ACAT. (wikipedia.org)
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. (childrensmercy.org)
Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA. (string-db.org)
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein. (string-db.org)
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. (smpdb.ca)
SYP7 group Qc-type SNARE protein","protein_coding" "MA_10436714g0010","No alias","Picea abies","acyl-CoA thioesterase","protein_coding" "MA_135972g0010","No alias","Picea abies","Acyl-CoA-binding domain-containing protein 3 OS=Oryza sativa subsp. (ntu.edu.sg)

3-ketoacyl-CoA synthase n=1 Tax=Physcomitrella patens subsp. (uma.es)

It can also catalyze acetyl transfer between arylamines without COENZYME A and has a wide specificity for aromatic amines, including SEROTONIN. (wakehealth.edu)
Acetyl coenzyme A (acetyl-CoA) is a reactive metabolite that nonproductively hydrolyzes in a number of enzyme active sites in the crystallization time frame. (bvsalud.org)

Cannot accept L- tyrosine as substrate and propionyl-CoA, succinyl-CoA or (S)- methylmalonyl-CoA as acyl donors. (string-db.org)
In order to elucidate the enzyme-acetyl-CoA interactions leading to catalysis, acetyl-CoA substrate analogs are needed. (bvsalud.org)

Alternatively, as part of pathway IV ( link ), glutarate can be activated to glutaryl-CoA by a CoA-transferase. (lbl.gov)
Comment: In MetaCyc pathway glutaryl-CoA degradation ( link ), glutaryl-CoA is oxidized to (E)-glutaconyl-CoA and oxidatively decarboxylated to crotonyl-CoA (both by the same enzyme), hydrated to 3-hydroxybutanoyl-CoA, oxidized to acetoacetyl-CoA, and cleaved to two acetyl-CoA. (lbl.gov)

Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. (thermofisher.com)
It catalyzes the transfer of long-chain fatty acids, preferentially unsaturated fatty acids, to lysophosphatides with the formation of 1,2-diacylglycero-3-phosphocholine and CoA. (wakehealth.edu)
Fatty acid and polyketide biosynthetic enzymes exploit the reactivity of acyl- and malonyl-thioesters for catalysis. (bvsalud.org)

Here, structures of chloramphenicol acetyltransferase III (CATIII) and Escherichia coli ketoacylsynthase III (FabH) from crystals grown in the presence of partially hydrolyzed AcOCoA and the respective nucleophile are presented. (bvsalud.org)

An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. (wakehealth.edu)
However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also referred to as SEROTONIN ACETYLTRANSFERASE. (wakehealth.edu)
One FabH structure contains a hydrolyzed AcOCoA product oxa(dethia)CoA (OCoA), while the other FabH structure contains an acyl-enzyme intermediate with OCoA. (bvsalud.org)

citramalyl-CoA lyase [Source:HGNC Symbo. (gsea-msigdb.org)

This process is governed by the ER acetylation machinery: the cytosol:ER-lumen acetyl-CoA transporter AT-1 (also known as SLC33A1), and the ER-resident lysine acetyltransferases ATase1 and ATase2 (also known as NAT8B and NAT8, respectively). (biologists.com)

Catalyzes the N-acetylation of L-phenylalanine and L- methionine using acetyl-CoA as acetyl donor in vitro. (string-db.org)

Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2). (smpdb.ca)

Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). (smpdb.ca)

This graph shows the total number of publications written about "Arylamine N-Acetyltransferase" by people in this website by year, and whether "Arylamine N-Acetyltransferase" was a major or minor topic of these publications. (wakehealth.edu)

A mitochondrial matrix enzyme that catalyzes the synthesis of L-GLUTAMATE to N-acetyl-L-glutamate in the presence of ACETYL-COA. (uchicago.edu)
Five proteins were included in more than two pathways: pyruvate dehydrogenase (PDH) E1 component subunit-α (PDHA), dihydrolipoamide S-acetyltransferase (DLAT), PDH E1 component subunit-β (PDHB), dihydrolipoamide dehydrogenase (DLD) and aldehyde dehydrogenase, mitochondrial precursor (ALDH2). (medscape.com)
Following the reaction, the newly synthesized acylcarnitine is transported into the mitochondrial matrix by a mitochondrial carnitine/acylcarnitine carrier protein found in the mitochondrial inner membrane. (smpdb.ca)
Once in the matrix, (10Z)-pentadec-10-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form (10Z)-pentadec-10-enoyl-CoA and L-carnitine. (smpdb.ca)
10Z)-Pentadec-10-enoyl-CoA then enters into the mitochondrial beta-oxidation pathway to form aceytl-CoA. (smpdb.ca)
Mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency (OMIM#203750, *607809) is a rare inherited disorder of isoleucine amino acid catabolism and ketone body metabolism. (biomedres.us)
2-methylacetoacetyl CoA thiolase deficiency (which is also known as Beta-ketothiolase deficiency, T2 deficiency, 3-oxothiolase deficiency, alpha-methyl acetoacetic aciduria, 2-methyl-3-hydroxybutyric acidemia, and mitochondrial acetoacetyl-CoA thiolase deficiency) is an autosomal recessive inborn error of metabolism and classified as a ketolysis disorder or organic aciduria disorder. (biomedres.us)

2-methylacetoacetyl CoA thiolase encodes by ACAT1 gene and acts at the end stage of isoleucine amino acid catabolism pathway. (biomedres.us)
2-methylacetoacetyl CoA thiolase enzyme acts at the end stage of isoleucine amino acid catabolism pathway and is involved in the ketone body metabolism [1] (Figure 1). (biomedres.us)
Funciton: Beta-ketoadipyl CoA thiolase (EC 2.3.1. (lbl.gov)

Beta-ketothiolase caused by defects in the acetyl-CoA acetyltransferase 1 (ACAT1) gene. (biomedres.us)

Other names in common use include acetyl coenzyme A-acyl-carrier-protein transacylase, Acetyl CoA:ACP transacylase, [acyl-carrier-protein]acetyltransferase, [ACP]acetyltransferase, and ACAT. (wikipedia.org)
Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase. (nih.gov)

The systematic name of this enzyme class is acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase. (wikipedia.org)

acetyl-CoA carboxylase alpha [Source:HG. (gsea-msigdb.org)

This enzyme is also referred to as serotonin acetylase despite the fact that serotonin acetylation can also occur through the action of broad specificity acetyltransferases such as ARYLAMINE N-ACETYLTRANSFERASE. (wakehealth.edu)

Amino-Acid N-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)

601 1-acyl-sn-glycerol-3-phosphate acyltransferase plsC BBZA01000001 CDS ARMA_0002 604. (go.jp)
a) Kennedy pathway dependent on acyl-CoA and (b) the phospholipid diacylglycerol acyltransferase (PDAT) mediated alternative pathway, which uses fatty acids from lipids turnover. (biomedcentral.com)

Many acyl-CoA groups will then further react with other zwitterionic compounds such as carnitine (to form acylcarnitines) and amino acids (to form acyl amides). (smpdb.ca)
In forming an acylcarnitine derivative, (10Z)-pentadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-pentadec-10-enoylcarnitine. (smpdb.ca)
Acetyl-CoA can go on to enter the TCA cycle, or it can react with L-carnitine to form L-acetylcarnitine in a reaction catalyzed by Carnitine O-acetyltransferase. (smpdb.ca)
This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. (smpdb.ca)
Finally, acetyl-CoA in the cytosol can be catalyzed by acetyl-CoA carboxylase 1 to form malonyl-CoA, which inhibits the action of carnitine O-palmitoyltransferase 1, thereby preventing (10Z)-pentadec-10-enoylcarnitine from forming and thereby preventing it from being transported into the mitochondria. (smpdb.ca)
The diagnosis of this disorder is straightforward and includes an elevated level of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid and tiglylglycine in urine organic acids analysis and elevated levels of acylcarnitines C5:1 and C5OH in blood acyl carnitine profile analysis [5]. (biomedres.us)

The general role of acylcarnitines is to transport acyl-groups, organic acids and fatty acids, from the cytoplasm into the mitochondria so that they can be broken down to produce energy. (smpdb.ca)
Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives. (lookformedical.com)

Regulation also occurs via end product inhibition (by acetyl CoA and NADH). (ferienwohnung-gluecksburg.net)

Here, structures of chloramphenicol acetyltransferase III (CATIII) and Escherichia coli ketoacylsynthase III (FabH) from crystals grown in the presence of partially hydrolyzed AcOCoA and the respective nucleophile are presented. (nih.gov)

acyl-CoA thioesterase 9 [Source:HGNC. (gsea-msigdb.org)

Predicted structure of this domain disclosed a region similar to malonyl-CoA:acyl-carrier protein (ACP) transacylases (MATs). (nih.gov)

12558 2-aminobenzoate-CoA ligase abmG BBZA01000002 CDS ARMA_0024 12542. (go.jp)
This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups. (smpdb.ca)
Ghosh B, Barbosa E, Singh I: Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression. (smpdb.ca)

14478 3-oxoacyl-[acyl-carrier protein] reductase fabG BBZA01000001 CDS ARMA_0014 complement(14430. (go.jp)
In all cases, Ter from Treponema denticola was the preferred trans-enoyl-CoA reductase. (biomedcentral.com)

The PTEN download Windows for HSF1( HSE, aspartate symbol uridine) covers transfer of new transcripts acid in well-being SUMOylation, with at least three Laminins representing annealed for the transcriptional phosphate acetyl. (evakoch.com)

MATs play a key role transferring precursor CoA thioesters from solution onto FASs and PKSs for chain elongation. (nih.gov)

We also co-expressed a butyryl-CoA pathway variant to increase the butyryl-CoA pool and support the chain extension. (biomedcentral.com)

Mao J, Chirala SS, Wakil SJ: Human acetyl-CoA carboxylase 1 gene: presence of three promoters and heterogeneity at the 5'-untranslated mRNA region. (smpdb.ca)

The observed correlation depends mainly on the acyl chain length. (bvsalud.org)

CoA-transferase family III [Interproscan]. (ntu.edu.sg)

dephospho-CoA kinase domain containi. (gsea-msigdb.org)

Once inside the cell it undergoes a reaction to form an acyl-CoA derivative called (10Z)-pentadec-10-enoyl-CoA. (smpdb.ca)

people proceed into 7-mediated short carriers with less H+ sister cells. (evakoch.com)

This graph shows the total number of publications written about "Arylalkylamine N-Acetyltransferase" by people in this website by year, and whether "Arylalkylamine N-Acetyltransferase" was a major or minor topic of these publications. (wakehealth.edu)
Below are the most recent publications written about "Arylalkylamine N-Acetyltransferase" by people in Profiles. (wakehealth.edu)

Anatomy15

Organisms16

Chemicals and Drugs128

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes56

Technology, Industry, Agriculture4

Information Science4

Health Care1

Dehydrogenase2

Acyltransferase1

Protein7

Synthase1

Coenzyme2

Substrate2

Glutaryl-CoA2

Fatty3

Chloramphenicol acetyltransferase1

Enzyme3

Lyase1

Lysine1

Acetylation1

Converts1

Catalyzes1

Major1

Mitochondrial7

Thiolase3

Acat11

Transacylase2

Protein S-Acetyltransferase1

Carboxylase alpha1

ARYLAMINE N-ACETYLTRANSFERA1

Amino-Acid N-Acetyltran1

Acyltransferase2

Carnitine6

Fatty acids2

NADH1

Escherichia1

Thioesterase1

Transacylases1

Ligase3

Reductase2

Phosphate1

Precursor1

Pathway1

Gene1

Chain1

Family1

Domain1

Form1

Short1

People2