• A panel of rare and functionally defective genetic variants in the sialic acid acetylesterase (SIAE) gene has recently been implicated in several common autoimmune conditions. (nih.gov)
  • Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. (cdc.gov)
  • Scientists have discovered that rare variants of a gene that encodes the enzyme sialic acid acetylesterase (SIAE) are associated with several autoimmune diseases, especially rheumatoid arthritis and Type 1 diabetes. (nih.gov)
  • The enzyme pectin acetylesterase (EC 3.1.1.6) can specifically hydolyze such acetyl esters in homogalacturonan regions of pectin, thus it may play a critical role in cell wall modification during root development and during pest/pathogen interactions. (usda.gov)
  • This study describes how one pectin-modifying enzyme, PECTIN ACETYLESTERASE 9 (PAE9), affects the Arabidopsis (Arabidopsis thaliana) transcriptome, secondary metabolome, and aphid performance. (scilifelab.se)