Torsades de PointesPhosphoric Diester HydrolasesLong QT SyndromeMutationCells, CulturedDNA Breaks, Single-StrandedRNA, MessengerMolecular Sequence DataDNA Topoisomerases, Type ICell LineGlycolatesTime FactorsKineticsPhenethylaminesBiological TransportAmino Acid SequenceCell NucleusDisease Models, AnimalMice, Inbred C57BLDose-Response Relationship, DrugMice, KnockoutGene Expression Regulation, PlantAnti-Arrhythmia AgentsBase SequenceLiverLipid MetabolismSignal TransductionDNA BreaksDNA DamagePlant LeavesRabbitsDNA RepairDogsPlant ProteinsSotalolModels, BiologicalDNA-Binding ProteinsThiamine MonophosphateElectrocardiographyTranscription, GeneticCell Line, TumorBlotting, WesternPlants, Genetically ModifiedArabidopsisSulfonamidesNuclear ProteinsFibroblastsCyclic AMPTissue DistributionGene Expression RegulationLysosomesPhenotypeApoptosisMice, TransgenicPhosphorylationHeart BlockProtein TransportTopoisomerase I InhibitorsBenzamidinesGene ExpressionMacrophagesImmunohistochemistryTobaccoAtrioventricular BlockPhosphoamino AcidsEnzyme InhibitorsCytoplasmTranscription FactorsCarrier ProteinsGlucoseSaccharomyces cerevisiaeBrainPlant RootsDiminazeneMitochondriaProtein BindingArabidopsis ProteinsPhosphodiesterase InhibitorsRats, Sprague-DawleySpinocerebellar AtaxiasCell MembraneTransfectionTumor Cells, CulturedMembrane ProteinsMicroscopy, FluorescenceHydrogen-Ion ConcentrationCalciumCamptothecinReverse Transcriptase Polymerase Chain ReactionDNAMicroscopy, ElectronCholesterolAcetanilidesOxidative StressPlant DiseasesCell DivisionCell SurvivalOxidation-ReductionCell Cycle3-Mercaptopropionic Acid