Abstract lyme disease. Medical search. Frequent questions

December 20th, 2013 Public Library of Science Borrelia burgdorferi, the bacterium that causes Lyme disease, hitchhikes in ticks for dissemination to mammalian hosts-including humans. (canlyme.com)
In the case of Lyme disease, that usually includes a two-step process to test the blood for the presence of antibodies against the bacteria that causes Lyme disease, the first step being an enzyme immunoassay, which, if negative rules out Lyme disease. (scienceblogs.com)
White-footed mice are important reservoir hosts for the pathogen that causes Lyme disease in people. (usda.gov)
The blacklegged tick, Ixodes scapularis, is the vector of Borrelia burgdorferi, the etiological agent that causes Lyme disease in the United States. (usda.gov)
If transmitted to humans, B. burgdorferi causes Lyme disease, an infection which can impair different organs, such as the skin, joints, nervous system and heart. (dissertations.se)
What causes Lyme disease? (medlineplus.gov)

Lyme disease, known commonly outside the U.S. as Lyme borreliosis, is caused by infection with tick-borne spirochetes of the Borrelia burgdorferi sensu lato complex. (health.mil)
The presence or absence of chronic Lyme borreliosis may be objectively adjudicated by tissue examinations which demonstrate or which fail to show pathogenic microbes in patients who have received a full course of antibiotics. (canlyme.com)
Co-infections represent an emerging problem because they might exacerbate Lyme disease clinical features, they can also mimic Lyme borreliosis sharing common manifestations, and eventually they can change the course of the disease itself. (opendermatologyjournal.com)
Lyme disease, also called borreliosis , is the most common vector-borne disease in the Northern hemisphere. (neurosciencenews.com)
Role of VIsE/C6 antigen as a marker for early Lyme borreliosis diagnosis and monitoring the effectiveness of its treatment. (aaem.pl)
Comparison of test with antigen VlsE (C6) with tests with recombinant antigens in patients with Lyme borreliosis. (aaem.pl)
Cinco M, Murgia R. Evaluation of the C6 enzyme-linked immuno-adsorbent assay for the serodiagnosis of Lyme borreliosis in north-eastern Italy. (aaem.pl)
Lipid Profiles in Lyme Borreliosis: A Potential Role for Apheresis? (uzh.ch)
Due to its excellent sensitivity and specificity combined with ease of evaluation, this line immunoblot assay offers a useful improvement in serodiagnosis of Lyme borreliosis. (drcremers.com)
Improvement of Lyme borreliosis serodiagnosis by a newly developed recombinant immunoglobulin G (IgG) and IgM line immunoblot assay and addition of VlsE and DbpA homologues. (drcremers.com)
To verify sensitivity and specificity, both blots were evaluated for reactivity with Borrelia-specific immunoglobulin G (IgG) and IgM antibodies with 85 sera from patients with different manifestations of Lyme borreliosis and 110 controls. (drcremers.com)
Lyme disease or Lyme borreliosis is the most prevalent tick-borne disease in America. (suny.edu)

Inpatient diagnoses were identified according to primary and secondary Lyme disease diagnosis codes ( 4 ). (cdc.gov)
To adjust for this undercoding of medical records, we applied a correction factor by using data from 3 studies on the proportion of medical records that contain the ICD-9 code 088.81 and meet the confirmed, probable, and suspect Lyme disease surveillance case definitions (as a proxy for clinician diagnosis). (cdc.gov)
The working differential diagnosis for the patient included multiple sclerosis, vascular insult, diabetic neuropathy, intracranial mass, dural venous sinus thrombosis, and Lyme disease. (hindawi.com)
BACKGROUND Although rapid diagnosis of Lyme disease is essential for effective treatment, there is concern about inappropriate testing. (annfammed.org)
Early diagnosis and treatment are essential to prevent complications from disseminated disease. (health.mil)
1 Clinicians trained in the U.S. who practice internationally or who commonly treat international travelers should understand the universal commonalities and region-specific differences in the microbiology, presentation, and diagnosis of Lyme disease. (health.mil)
Patients may present with Lyme disease in either a primary care or hospital setting, with an unknown proportion receiving confirmatory laboratory diagnosis. (biomedcentral.com)
Diagnosis and treatment of tick-borne diseases recommendations of the Polish Society of Epidemiology and Infectious Diseases. (aaem.pl)
Given the variability of Lyme disease symptoms, any diagnosis prior to 1982 must be considered circumstantial at best. (wattsupwiththat.com)
Because the dates of onset or diagnosis for notifiable diseases are not always reported, these surveillance data are presented by the year and week they were reported to CDC by public health officials in state and territorial health departments. (cdc.gov)
Chronic lyme disease is another prototypical fake medical diagnosis . (scienceblogs.com)
This should be contrasted to Lyme disease, which is a real diagnosis and a real disease caused by the tick-borne bacterium Borrelia burgdorferi . (scienceblogs.com)
The diagnosis of Lyme disease is based o nits symptoms, physical findings (e.g., the characteristic skin rash, which looks like a bull's eye), and a history of being in an area where exposure to ticks is possible. (scienceblogs.com)
At least five five randomized, placebo-controlled studies have shown that prolonged courses of IV antibiotics do not improve long-term outcome for patients with a diagnosis of chronic Lyme disease (e.g., this one ). (scienceblogs.com)
These potential complications have been illustrated in a recent article in the CDC's Morbidity and Mortality Weekly Report (MMWR), Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease . (scienceblogs.com)
The term "chronic Lyme disease" is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2). (scienceblogs.com)
Patients with a diagnosis of chronic Lyme disease have been provided a wide range of medications as treatment, including long courses of intravenous (IV) antibiotics (3,4). (scienceblogs.com)
Collection of articles on Lyme disease diagnosis, symptoms and treatments. (lymeinfo.net)
In conclusion, B. miyamotoi infection should be considered in the differential diagnosis for flu-like syndromes during the summer after a deer tick bite and to prevent labeling a case with Lyme disease. (biomedcentral.com)
Pedi Lyme Net 2023, ' Racial Differences in the Diagnosis of Lyme Disease in Children ', Clinical Infectious Diseases , vol. 76, no. 6, pp. 1129-1131. (northwestern.edu)
Black children with Lyme disease were more likely to have arthritis rather than cutaneous findings at the time of diagnosis. (jucm.com)
While a less obvious EM rash may drive this pattern of diagnosis, it's worth noting that other social determinants of health associated with race other than skin tone may also lead to later presentations in cases of Lyme. (jucm.com)
Metabolites detectible in human biofluids are attractive biomarkers for the diagnosis of early Lyme disease (ELD), a vector-borne infectious disease. (cdc.gov)
Standard two-tiered testing (STTT) is the recommended algorithm for laboratory diagnosis of Lyme disease (LD). (cdc.gov)
Correct diagnosis with timely and appropriate therapy is key to reducing disease-associated morbidity. (medscape.com)

In eastern North America, the vector of the Lyme disease causing bacterium B. burgdorferi sensu stricto ( B. burgdorferi s.s. hereafter) is the blacklegged tick, Ixodes scapularis , which has three parasitic stages in its life cycle: larva, nymph, and adult. (nature.com)
The bacterium which causes Lyme wasn't identified until 1982, when it was described by Willy Burgdorfer . (wattsupwiththat.com)
Scientific literature that covers Lyme disease symptoms, seronegativity (negative blood tests), persistent infection despite treatment, and the cystic form of the Lyme disease bacterium. (lymeinfo.net)
Human monocytic ehrlichiosis (HME) is a sometimes fatal, emerging tick-borne disease caused by the bacterium Ehrlichia chaffeensis. (google.com)
Lyme disease (LD) is caused by Borrelia burgdorferi , a bacterium transmitted through the bite of infected Ixodes species ticks. (cdc.gov)

Lyme disease is caused by Borrelia burgdorferi spirochetes, which are transmitted to humans by certain Ixodes spp. (cdc.gov)
This study used an established spatial analysis method to determine likely high-risk areas for contracting Lyme disease from ticks ( Ixodes scapularis ) near West Point, NY. (health.mil)
https://doi.org/10.1016/j.ttbdis.2019.06.001 Abstract Fifty nymphal Ixodes ricinus ticks collected in Alsace, France, identified by morphological criteria and using MALDI-TOF MS, were tested by PCR to detect tick-associated bacteria and protozoan parasites. (canlyme.com)
White-tailed deer ( Odocoileus virginianus Zimmerman), serve as the primary host for the adult blacklegged tick (Ixodes scapularis Say), the vector for Lyme disease, human babesiosis, and human granulocytic anaplasmosis. (bioone.org)
In recent years co-infections represent an emerging issue in Lyme disease spectrum because in addition to Borrelia burgdorferi sl many other potential pathogens may be transmitted by hard ticks Ixodes species. (opendermatologyjournal.com)
In parts of eastern and central North America, blacklegged ticks, Ixodes scapularis , are the primary vector for the spirochete Borrelia burgdorferi sensu stricto (hereafter referred to as B. burgdorferi ), which is the causative agent of Lyme disease (LD) ( 3 ). (frontiersin.org)
Ixodes scapularis ticks transmit the Lyme disease agent in the United States. (uri.edu)
OBJECTIVE: To evaluate dogs as a sentinel species for emergence of Lyme disease in a region undergoing invasion by Ixodes scapularis. (tamu.edu)
however, it is transmitted by Ixodes scapularis , the same tick that transmits Borrelia burgdorferi (Lyme disease), Anaplasma phagocytophilum and Babesia microti [ 3 ]. (biomedcentral.com)
Lyme disease is caused by Borrelia burgdorferi infection which is transmitted by Ixodes ricinus . (bvsalud.org)
Predicting the speed of tick invasion: an empirical model of range expansion for the Lyme disease vector Ixodes scapularis in Canada. (britishecologicalsociety.org)
Over the past two decades, Ixodes scapularis , the primary tick vector of the Lyme disease pathogen Borrelia burgdorferi in North America has expanded its range northward from the USA to colonize new regions in southern Canada. (britishecologicalsociety.org)

Posted in Diseases/Syndromes , Ticks Bookmark the permalink . (osu.edu)
Risk for Lyme disease is dependent upon the number of ticks infected with B. burgdorferi, the density of ticks in the environment, and the extent of contact between a person and ticks. (pitt.edu)
This suggests that most Lyme disease cases in the past decade have been due to the tick population stabilizing in areas of suitability, or increased human-tick interaction in areas already suitable, rather than progression of ticks into new geographic areas due to climate change. (queensu.ca)
Tick eggs hatch sooner and ticks spend more time questing for blood, and so are increasingly likely to feast on a human and pass on a disease-causing pathogen. (wattsupwiththat.com)
Because more ticks survive and mature more quickly, diseases can be transmitted faster. (wattsupwiththat.com)
Studies of host-targeted tick control and disease ecology, including interactions among mice, ticks and tick-borne pathogens in nature require proper methods for marking of wild white-footed mice. (usda.gov)
The study provides useful information regarding mouse-marking methodology that can be used by wildlife biologists, researchers who study ticks and tick-borne disease epidemiology, as well as vector control professionals. (usda.gov)
In areas of low tick density, use of dogs as a source of ticks is preferable to serosurvey for surveillance of emerging Lyme disease. (tamu.edu)
IMPACT FOR HUMAN MEDICINE: By retaining ticks from dogs for identification and pathogen testing, veterinarians can play an important role in early detection in areas with increasing risk of Lyme disease. (tamu.edu)
Borrelia miyamotoi is an emerging pathogen that causes a febrile illness and is transmitted by the same hard-bodied (ixodid) ticks that transmit several other pathogens, including Borrelia species that cause Lyme disease. (lymediseaseincanada.com)

In North America, the vast majority of Lyme disease is caused by B. burgdorferi sensu stricto, 1 although other presumably pathogenic genospecies have been isolated. (health.mil)
Transmission of Lyme disease in North America is through the deer tick, which take blood meals from infected white tailed deer. (suny.edu)
Lyme disease is a tick-borne bacterial illness that occurs in areas of North America, Europe, and Asia. (cdc.gov)

Left untreated, B. burgdorferi can disseminate over days to weeks, and develop into multiple EM rashes, acute neuroborreliosis (e.g., meningitis, facial palsy, or radiculopathy), or Lyme carditis. (cdc.gov)

Lyme disease is a tick-transmitted multisystem inflammatory disease caused by the spirochete Borrelia burgdorferi . (hindawi.com)
Lyme disease, a multisystem illness caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States. (mssm.edu)
The etiological agent of Lyme disease is the Borrelia spirochete. (suny.edu)
Advancing understanding of the survival mechanisms of the Lyme disease spirochete carry noteworthy implications for ongoing research and clinical practice. (lymeresourcecentre.com)
If the Lyme spirochete can adapt to the human brain and circumvent the immune system, it is less likely to be inhibited by our natural immune defenses. (medicpdf.com)

3, 4, 8- 10 A test was defined as appropriate if the patient had any objective findings consistent with disseminated Lyme disease, including joint, neurologic, or cardiac symptoms, such as arthritis, lymphocytic meningitis, cranial neuritis, or atrioventricular conduction defects. (annfammed.org)
The symptoms resulting from Lyme disease and possible PTLDS may render service members non-deployable and may result in medical separations from service. (health.mil)
Males and females with early Lyme disease had a similar likelihood of having multiple erythema migrans skin lesions and had a similar number of additional subjective symptoms, such as fatigue, at study entry. (nih.gov)
Three patients, each of whom had required intensive open-ended antimicrobial therapy for control of the symptoms of chronic relapsing neurological Lyme disease and relapsing babesiosis, were able to discontinue treatment and remain clinically well for periods of observation of 6-23 months following the completion of a finite course of treatment solely with disulfiram. (canlyme.com)
This population entering secondary care through A&E suggest a poor understanding of the recommended care pathways for symptoms related to Lyme disease by the general population. (biomedcentral.com)
Lyme disease is associated with a range of clinical presentations which may vary as infection progresses, though it commonly presents as erythema migrans with associated flu-like symptoms [ 5 ]. (biomedcentral.com)
The standard of care for Lyme disease, a course of antibiotics over 2-4 weeks, is not always effective: at least 10-20% of treated patients continue to experience symptoms after treatment. (neurosciencenews.com)
Many thousands of Lyme patients today, especially those with later-stage symptoms who have not been effectively treated, are in great need of efficacious, accessible treatment options," says Dr Sunjya K. Schweig, CEO and co-Director of the California Center for Functional Medicine and Scientific Advisory Board Member of the Bay Area Lyme Foundation. (neurosciencenews.com)
At 3-4 months post-treatment, 50% of patients reported recurrence of the disease symptoms. (aaem.pl)
Lyme disease symptoms include fever, headache, and fatigue, and it's characterized by a skin rash known as erythema migrans. (scienceblogs.com)
Alternative medicine practitioners claim that Lyme infection can become chronic and attribute a vague constellation of symptoms not unlike the vague constellation of symptoms attributed to adrenal fatigue to chronic Lyme infection, a condition they commonly refer to as chronic Lyme disease . (scienceblogs.com)
Now, there is a condition known as posttreatment Lyme disease syndrome, which is the proper term for patients with a verified previous B. burgdorferi infection who experience fatigue, arthralgias, or other symptoms six months or more after antibiotic treatment when all other conditions have been ruled out. (scienceblogs.com)
However, there is no evidence that this syndrome is caused by chronic B. burgdorferi infection, nor is there any good evidence that prolonged treatment with antibiotics benefits patients with persistent symptoms after treatment for Lyme disease-quite the contrary, actually. (scienceblogs.com)
Yet these "Lyme literate" physicians and a coterie of naturopaths treat patients with symptoms after Lyme disease for weeks, months, or even years of antibiotics, and there are many known complications to long term antibiotic treatment. (scienceblogs.com)
Chronic Lyme disease symptoms, treatment and other resources. (lymeinfo.net)
Lists fun websites to entertain those with Lyme disease symptoms. (lymeinfo.net)
Details Lyme disease autonomic dysfunction symptoms and treatment. (lymeinfo.net)
Since rheumatic symptoms have sometimes been reported following cat scratch disease, the researchers wanted to see if these patients tested positive for B. henselae . (ncsu.edu)
In a nutshell it comes down to the inescapable fact that victims of Lyme disease all too often have lingering symptoms that remain or return even after aggressive and multiple antibiotic treatments. (medicpdf.com)
We know for example that if you rank all the known Borrelia pathogens in a phylogenetic tree based on related genetics, you will find many disease causing pathogens that cause similar symptoms will often end up close together in related groups on the phylogenetic family-tree. (medicpdf.com)
Could pathogen-host interactions based on patient genetic markers explain why some Lyme patients have persisting symptoms? (medicpdf.com)
Fever will report a Bull's-Eye rash identical to Lyme disease, and experience symptoms similar to Lyme without a recurring febrile states (Recurring fevers). (medicpdf.com)
At first, Lyme disease usually causes symptoms such as a rash , fever , headache , and fatigue . (medlineplus.gov)
What are the symptoms of Lyme disease? (medlineplus.gov)
Early symptoms of Lyme disease start between 3 to 30 days after an infected tick bites you. (medlineplus.gov)
If you have been treated for Lyme disease and still feel unwell, contact your health care provider about how to manage your symptoms. (medlineplus.gov)
For the majority (70%-80%) of cases, the disease begins with a characteristic erythema migrans (EM) rash and accompanying flu-like symptoms [3]. (cdc.gov)
Elderly individuals, especially those with underlying comorbidities (eg, diabetes, renal and liver disease), may present with lethargy and an absence of meningeal symptoms. (medscape.com)

We found that both the abundance of small mammal hosts and the relative abundance of the tick's natural host, the white-footed mouse ( Peromyscus leucopus ), influenced measures of disease risk in tick vectors ( Borrelia burgdorferi infection abundance and prevalence in tick vectors). (nature.com)
Spread through the bite of an infected blacklegged tick, infection with the bacterial cause of Lyme disease can have lasting effects that may lead to medical discharge from the military. (health.mil)
Lyme disease is the most common vector-borne infection in the United States with 300,000 estimated cases per year. (nih.gov)
A group of physicians who like to refer to themselves as "Lyme literate" physicians describe patients whom they believe have persistent B. burgdorferi infection, claiming that the condition requires long-term antibiotic treatment. (scienceblogs.com)
Neuroborreliosis, infection of the nervous system by B. burgdorferi, may occur during early disseminated or late persistent disease. (mssm.edu)
Rheumatic heart disease is characterized by the priming of the immune system by a group A streptococcal infection leading to host autoimmunity. (acponline.org)
B. miyamotoi infection can clinically present during warm months as a flu-like syndrome similar to Lyme disease, Anaplasmosis, or Babesiosis. (biomedcentral.com)
Antibiotics are effective in clearing infection and are the same as those used for Lyme disease, including doxycycline, tetracycline, erythromycin, penicillin, and ceftriaxone. (lymediseaseincanada.com)
Is chronic illness in patients with Lyme disease caused by persistent infection? (lymeresourcecentre.com)
Lyme disease is a bacterial infection you get from the bite of an infected tick . (medlineplus.gov)
Most Lyme disease tests check for antibodies made by the body in response to infection. (medlineplus.gov)

ABSTRACT Objective: Here we describe a rare case of systemic sarcoidosis in a healthy young man with neuroborreliosis as a putative trigger. (canlyme.com)
In patients with early disseminated neuroborreliosis, treatment with antibiotics often leads to rapid recovery and may prevent further complications of Lyme disease. (mssm.edu)
Dissemination of the pathogen Borrelia burgdorferi can result in multiple EM skin lesions or in extracutaneous manifestations such as Lyme neuroborreliosis. (cdc.gov)

Ethnobotanical plant extracts, including Ghanaian quinine and Japanese knotweed, show strong activity against B.burgdorferi, outperforming current antibiotics for the treatment of Lyme disease. (neurosciencenews.com)

The conventional 2-tiered serologic testing protocol for Lyme disease (LD), an enzyme immunoassay (EIA) followed by immunoglobulin M and immunoglobulin G Western blots, performs well in late-stage LD but is insensitive in patients with erythema migrans (EM), the most common manifestation of the illness. (nih.gov)
1, 2 Erythema migrans, the characteristic expanding rash of early localized Lyme disease, is present in at least 80% of cases, and joint, neurologic, cardiac and other manifestations may develop. (annfammed.org)
3 In the absence of erythema migrans, antibodies to B burgdorferi are generally required to diagnose Lyme disease. (annfammed.org)
8 For patients who live in areas where Lyme disease is endemic, and who have erythema migrans, serologic testing is not routinely recommended. (annfammed.org)
Erythema migrans (EM) is commonly felt to represent the first clinical finding in patients with Lyme disease. (jucm.com)
Erythema migrans, a rash spreading from the site of a tick bite , is the earliest and most common manifestation of the disease . (bvsalud.org)

No useful method to genetically manipulate Borrelia burgdorferi, the causative agent of Lyme disease, has been developed previously. (umt.edu)

A Decrease in the Immuno-globulin G Antibody Response against the VlsE Protein of Borrelia burgdorferi Sensu Lato Correlates with the Resolution of Clinical Signs in Antibiotic-Treated Patients with Early Lyme Disease. (aaem.pl)
Metabolic biosignatures of patients with early Lyme disease can potentially provide diagnostic targets as well as highlight metabolic pathways that contribute to pathogenesis. (cdc.gov)

Lyme disease, if not diagnosed early, can result in post-treatment Lyme disease syndrome (PTLDS). (health.mil)

2-5 Pathogen diversity is greater in Europe, where B. burgdorferi sensu stricto, B. afzelii , B. garinii , B. bavariensis , and B. spielmanii are established contributors to the burden of human disease. (health.mil)
Predicting spatio-temporal population patterns of Borrelia burgdorferi , the Lyme disease pathogen. (britishecologicalsociety.org)

The patients had previously been diagnosed with conditions ranging from Lyme disease to arthritis to chronic fatigue. (ncsu.edu)
An Editorial by Tom Grier, Lyme Writer In 1975 the term "Lyme Arthritis" first entered the vocabulary of the physicians in America. (medicpdf.com)
But in the 28 years since "Lyme Arthritis" was first described: What do we actually know? (medicpdf.com)

SPECT brain imaging in chronic Lyme disease. (canlyme.com)
Helpful resources for those newly diagnosed with acute or chronic Lyme disease. (lymeinfo.net)
Covers alternative treatments and therapies for chronic Lyme disease. (lymeinfo.net)
Health resources of particular interest to patients with chronic Lyme disease. (lymeinfo.net)
Covers chronic Lyme disease pain and headaches. (lymeinfo.net)

Looking at Lyme is an educational podcast created by the Canadian Lyme Disease Foundation, designed to increase awareness and empower listeners with expert knowledge. (canlyme.com)

This was a prospective cohort study at eight EDs participating in the Pedi Lyme Net clinical research network in the eastern U.S. The study enrolled children undergoing clinical evaluation for Lyme disease. (jucm.com)

Lyme disease (LD) is the most frequently reported vector-borne disease in the U.S., with over 36,429 confirmed and probable cases in 2016. (health.mil)

Our results suggest that the increase in Lyme disease risk is modulated by regional processes involving the abundance and composition of small mammal assemblages. (nature.com)
It is unknown whether the increase in Lyme disease cases is due to climate change, changes in host abundance, host and vector migration, or a combination of these factors. (queensu.ca)

The majority of Lyme disease cases occur in the Northeast, mid-Atlantic, and upper Midwest regions. (osu.edu)

There are 3 clinical stages of Lyme disease: early localized, early disseminated, and late persistent disease. (mssm.edu)
Spinal cord involvement in early disseminated disease is extremely rare. (mssm.edu)
The authors present the clinical and radiographic findings, both before and after treatment, in a patient with meningoradiculomyelitis due to early disseminated Lyme disease. (mssm.edu)
Sera from well-characterized patients diagnosed with either early localized Lyme disease (ELL) or early disseminated Lyme disease (EDL), plus healthy controls (HC), from the United States were analyzed by liquid chromatography-mass spectrometry (LC-MS). Comparative analyses were performed between ELL, or EDL, or ELL combined with EDL, and the HC to develop biosignatures present in early Lyme disease. (cdc.gov)

The geographic distribution of Lyme disease in the United States and the demographic characteristics of persons affected have been well documented through nearly 3 decades of public health surveillance ( 2 ). (cdc.gov)
These statistics are collected and compiled from reports sent by state health departments to the National Notifiable Diseases Surveillance System (NNDSS), which is operated by CDC in collaboration with the Council of State and Territorial Epidemiologists (CSTE). (cdc.gov)
The Highlights section presents information on selected nationally notifiable diseases to provide a context in which to interpret surveillance and disease-trend data and to provide further information on the epidemiology and prevention of selected diseases. (cdc.gov)
These references provide additional information on surveillance and epidemiologic issues, diagnostic issues, or disease control activities. (cdc.gov)
Excerpts of papers by the Centers for Disease Control and Prevention (USA) regarding the Lyme disease surveillance criteria and under-reporting. (lymeinfo.net)
These projections suggest that prompt action is necessary to prepare the Canadian public for a likely epidemic of Lyme disease, with emphasis on focusing surveillance activities to confirm the locations of emerging Lyme disease risk. (britishecologicalsociety.org)
4,8 These global concerns are reflected in New Zealand with an increase in active surveillance for otential disease threats being advocated for the benefit of native wildlife, domestic stock and public health. (who.int)

In other words Borrelia burgdorferi, Borrelia afzellii and Borrelia garinii that cause Lyme disease in America and Europe are all genetically similar to each other and have similar tick vectors. (medicpdf.com)

Lepto: long-term therapy with sufficiently large doses may be required from an early stage of the disease until the appearance of antibodies. (science-bbs.com)

Military bases in endemic areas need to increase awareness of the local Lyme disease threat and facilitate the implementation of superior tick bite prevention measures. (health.mil)
The presence of one or more co-infecting agent during the course of Lyme disease may represent an issue especially in endemic areas for tick-borne diseases and in people occupationally exposed. (opendermatologyjournal.com)
The geographic expansion of B. miyamotoi in the US also extends to other Lyme endemic areas such as the Midwestern US. (biomedcentral.com)

In the present work, the capacity of Lyme disease (LD) Spirochetes to spontaneously adhere to rat lymphocytes has been evaluated. (fujita-hu.ac.jp)
Accumulating evidence indicates that Lyme disease spirochetes are adapted to persist in immune competent hosts, and that they are able to remain infective despite aggressive antibiotic challenge. (lymeresourcecentre.com)

We surveyed clinicians who submitted specimens for Lyme disease serologic testing (enzyme immunoassay or immunofluorescence assay) to 2 large clinical reference laboratories in Wisconsin. (annfammed.org)

This study provides the first convincing evidence that some of the herbs used by patients such as Cryptolepis, black walnut, sweet wormwood, cat's claw, and Japanese knotweed have potent activity against Lyme disease bacteria, especially the dormant persister forms, which are not killed by the current Lyme antibiotics," says Dr Ying Zhang from the Johns Hopkins Bloomberg School of Public Health. (neurosciencenews.com)
The Lyme bacteria Borrelia burgdorferi likes to preferentially express certain genes and suppress others. (medicpdf.com)
Lyme disease is caused by bacteria. (medlineplus.gov)

Covers the cognitive and psychiatric problems that can be caused by neurological Lyme disease. (lymeinfo.net)
If untreated, late manifestations of disseminated disease , mainly neurological and musculoskeletal, may occur. (bvsalud.org)

But some tick bites can transmit serious diseases, such as Lyme disease or Rocky Mountain spotted fever , to humans. (healthline.com)
Ehrlichiosis is a name used to describe several bacterial diseases that affect both animals and humans. (google.com)

Bilateral facial palsy is frequently linked with lyme disease. (uni-luebeck.de)

Lyme disease is an important emerging tick-borne disease caused by members of the spirochaetal complex Borrelia burgdorferi sensu lato. (biomedcentral.com)
In a new study published in Frontiers in Medicine , researchers from the Johns Hopkins Bloomberg School of Public Health, with colleagues at the California Center for Functional Medicine and Focus Health, surveyed the power of 14 plant-based extracts to kill Borrelia burgdorferi, compared to the currently used Lyme antibiotics doxycycline and cefuroxime. (neurosciencenews.com)
Genetic Transformation of the Lyme Disease Agent Borrelia Burgdorferi " by D. Scott Samuels, Kathleen E. Mach et al. (umt.edu)
Genetic Transformation of the Lyme Disease Agent Borrelia Burgdorferi with Coumarin-Resistant gyrB. (umt.edu)

A rash caused by Lyme does not always look like this and approximately 25% of those infected with Lyme disease may have no rash. (wattsupwiththat.com)
Most people with Lyme disease get this rash. (medlineplus.gov)

These findings are exciting as they offer opportunities for improved treatment of persistent Lyme disease, which is not helped by the current standard treatment. (neurosciencenews.com)
A worldwide ban on agricultural use was formalized under the Stockholm Convention on Persistent Organic Pollutants, but its limited and still-controversial use in disease vector control continues, because of its effectiveness in reducing malarial infections, balanced by environmental and other health concerns. (wattsupwiththat.com)

The purpose of this study was to compare the presenting clinical features and long-term outcome of males versus females with culture-confirmed early Lyme disease. (nih.gov)
Males and females with culture-confirmed early Lyme disease had similar clinical features, rates of seropositivity, and long-term outcomes. (nih.gov)
Furthermore, the discovery of new species of Borrelia has complicated the clinical picture of these diseases. (mdpi.com)
Lyme Disease Frontiers: Reconciling Borrelia Biology and Clinical Conundrums. (aaem.pl)
In this analysis we assessed the clinical and lipid profiles of 519 patients (319 women, 200 men) with a proven history of Lyme disease, before and after an extracorporeal double membrane filtration. (uzh.ch)
Clinical Infectious Diseases , 76 (6), 1129-1131. (northwestern.edu)

The Best Test to date for Lyme Disease: Recombinant VlsE of Borrelia garinii strain PBi displayed the highest sensitivity of all antigens tested for IgG detection and is also one of the most useful antigens for IgM. (drcremers.com)
Serum samples from the CDC Lyme Serum Repository were tested using three MTTTs: VlsE/C6, whole cell sonicate (WCS)/C6 and WCS/VlsE, and three STTTs (immunoblots preceded by three different first-tier assays: VlsE, C6 and WCS). (cdc.gov)

Cardiac Lyme includes orthostatic and neurally mediated hypotention and postural tachycardia syndrome. (lymeinfo.net)
[ 1-3 ] The most critical question in evaluating a patient with intraocular inflammation is whether the disease can be classified into a specific, defined syndrome. (medscape.com)
If the specific syndrome is elusive, one must take the appropriate steps to try to define the underlying pathophysiology, whether it be autoimmune, infectious, neoplastic or other masquerade syndromes, as the appropriate treatment for these types of diseases vary widely. (medscape.com)

As the most frequently reported vector-borne disease among active component U.S. service members, with an incidence rate of 16 cases per 100,000 person-years in 2011, Lyme disease poses both a challenge to health care providers in the Military Health System and a threat to military readiness. (health.mil)
In order to reduce the Lyme disease incidence rate in PA, it is recommended that the Pennsylvania Department of Health (PA DOH) implement a Lyme Disease Prevention Program (Program). (pitt.edu)
Part 1 contains tables showing incidence data for each of the diseases considered nationally notifiable during 2001. (cdc.gov)
95% confidence interval, 2.13-6.36) after adjustment for age and local Lyme incidence. (northwestern.edu)

In 2017, there were 523 cases of Lyme disease, 55 cases of Ehrlichiosis, 31 cases of Anaplasmosis, and 138 cases of Babesiosis [ 1 ]. (biomedcentral.com)

Lyme disease diagnostic workups conducted on active and retired U.S. service members and their dependents at U.S. Air Force military treatment facilities (MTFs) in Germany between 2013 and 2017 were assessed to determine the appropriateness of laboratory testing and antibiotic prescriptions. (health.mil)
Understanding the use and limitations of 2-tier diagnostic criteria, as well as the common pitfalls in diagnosing Lyme disease, may help prevent overdiagnosis, reduce unnecessary testing, and promote antibiotic stewardship. (health.mil)
Basically, fake diseases are diseases that do not exist in conventional medicine as diagnostic entities because there does not exist sufficient sufficient evidence to support them as one or there exists compelling evidence that they are not. (scienceblogs.com)
Appreciating these differences can help clinicians approach Lyme as a diagnostic consideration more equitably across ethnicities. (jucm.com)
Lyme was confirmed in 88 (9.2%) based on a diagnostic EM lesion alone, while 781 (81.6%) had a positive two-tier serology alone, and 88 (9.2%) had both. (jucm.com)
Diagnostic testing to identify major systemic diseases associated with uveitis. (medscape.com)

Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses. (qxmd.com)
Accounting for approximately 10% of blindness in the USA, uveitis refers to a group of heterogeneous diseases that share the features of intraocular inflammation but whose etiologies include idiopathic autoimmune disease, infections, rheumatologic diseases and masquerade syndromes. (medscape.com)

With more than 25,000 CDC reported cases annually, it has become the most common vector-borne disease in the United States. (hindawi.com)
With more than 25,000 cases reported annually to the CDC, Lyme disease has become the most common vector-borne disease in the United States [ 1 - 3 ]. (hindawi.com)
Lyme disease is the most commonly diagnosed vector-borne illness in the U.S. military. (health.mil)
Lyme disease is now the most common disease transmitted by a vector - a mosquito, tick, or other bug - in United States. (wattsupwiththat.com)

We conducted a prospective, cross-sectional survey of clinicians to assess the use and appropriateness of Lyme disease serologic tests (LDSTs). (annfammed.org)
3, 4 Approximately 2.8 million Lyme disease serologic tests (LDSTs) are performed each year in the United States according to a 1995 estimate. (annfammed.org)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
By Photo Credit: James GathanyContent Providers(s): CDC/ James Gathany - This media comes from the Centers for Disease Control and Prevention 's Public Health Image Library (PHIL), with identification number #9875 . (wattsupwiththat.com)
More than 30,000 cases are reported each year, and the Centers for Disease Control and Prevention estimates that 10 times as many Americans develop the disease. (wattsupwiththat.com)
A notifiable disease is one for which regular, frequent, and timely information regarding individual cases is considered necessary for the prevention and control of the disease. (cdc.gov)
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)
Nearly 30,000 confirmed cases were reported to the Centers for Disease Control and Prevention (CDC) in 2008 [1], ranking LD among the ten most commonly reported nationally notifiable diseases in the United States (U.S.). LD is a geographically focal illness, occurring predominantly in the Northeastern and North Central states. (cdc.gov)

The patient underwent outpatient lumbar puncture over a week after initiation of antibiotics, which was EIA negative for Lyme with negative Lyme PCR and was otherwise unremarkable. (hindawi.com)
Of the 83 positive Lyme disease IgM immunoblots conducted at U.S. Air Force MTF laboratories in Germany between 2013 and 2017, 40 (48.2%) were deemed false positives after standardized chart review, and 32 of these patients were prescribed antibiotics. (health.mil)
The usual treatment for Lyme disease is 2-4 weeks of antibiotics , which is highly effective. (scienceblogs.com)
Lyme disease is treated with antibiotics . (medlineplus.gov)

Published by Oxford University Press on behalf of Infectious Diseases Society of America. (northwestern.edu)

doi: 10.1097/RLU.0b013e318262ad9b Abstract OBJECTIVES: Lyme disease is an infectious disease that frequently involves the central nervous system, leading to cognitive and/or mood dysfunction. (canlyme.com)
B. henselae bacteremia was significantly associated with prior referral to a neurologist, most often for blurred vision, subcortical neurologic deficits, or numbness in the extremities, whereas B. koehlerae bacteremia was associated with examination by an infectious disease physician. (ncsu.edu)
6 Given the significant burden that EIDs place on global economies and public health, 1,7 the monitoring and mitigation of, and early response to, potential infectious disease threats are of the highest priority. (who.int)

Ninety-six percent of Lyme disease cases in the United States have been reported in high endemic New England and mid-Atlantic states, as well as Minnesota and Wisconsin [ 1 ]. (hindawi.com)
Our objective was to evaluate the degree of association between deer density, tick abundance, and human cases of Lyme disease in one Connecticut community over a 13-yr period. (bioone.org)
After hunts were initiated, number and frequency of deer observations in the community were greatly reduced as were resident-reported cases of Lyme disease. (bioone.org)
Number of resident-reported cases of Lyme disease per 100 households was strongly correlated to deer density in the community. (bioone.org)
Reducing deer density to 5.1 deer per square kilometer resulted in a 76% reduction in tick abundance, 70% reduction in the entomological risk index, and 80% reduction in resident-reported cases of Lyme disease in the community from before to after a hunt was initiated. (bioone.org)
Howard J. Kilpatrick , Andrew M. Labonte , and Kirby C. Stafford "The Relationship Between Deer Density, Tick Abundance, and Human Cases of Lyme Disease in a Residential Community," Journal of Medical Entomology 51(4), 777-784, (1 July 2014). (bioone.org)
As of 2013, Pennsylvania (PA) has the highest Lyme disease case count (number of cases) in the United States (US). (pitt.edu)
The number of Lyme disease cases in Ontario has increased in the last decade and is projected to continue to increase due to climate change. (queensu.ca)
The northern limit of Lyme disease cases in Ontario has also been progressing northward from the United States. (queensu.ca)
Zoonotic disease researcher Katharine Walter has claimed that climate is causing a massive rise in human cases of potentially debilitating Lyme Disease . (wattsupwiththat.com)
Cases of Lyme disease first appeared in 1976 in the woodsy suburb of Lyme, Connecticut. (wattsupwiththat.com)
Each year, approximately 30,000 cases of Lyme disease are reported to CDC by state health departments and the District of Columbia. (wattsupwiththat.com)
This publication also documents which diseases are considered national priorities for notification and the annual number of reported cases of such diseases. (cdc.gov)
The tables provide the number of cases of notifiable diseases reported to CDC for 2001, as well as the distribution of cases by month and geographic location and by patient's age, sex, race, and Hispanic ethnicity. (cdc.gov)
Because no cases of paralytic poliomyelitis, western equine encephalitis, or yellow fever were reported in the United States during 2001, these diseases do not appear in the tables in Part 1. (cdc.gov)
A series of cases in the Northeast of the US during 2013-2015 described a new Borrelia species, Borrelia miyamotoi , which is transmitted by the same tick species that transmits Lyme disease and causes a relapsing fever-like illness. (biomedcentral.com)
Four cases of Lyme disease in children are reported to illustrate the different presentations of this disease and its management in children . (bvsalud.org)

The strong effect of P. leucopus abundance on disease risk we report here is of significant concern, as this competent host is predicted to increase in abundance and occurrence in the region, with the northern shift in the range of North American species under climate warming. (nature.com)
The main co-infections found in Lyme disease described in this review are represented by Anaplasma phagocytophilum, Babesia species, Bartonella species, Rickettsiae species and tick-borne encephalitis virus . (opendermatologyjournal.com)
The most commonly known Bartonella -related illness is cat scratch disease, caused by B. henselae , a species of Bartonella that can be carried in a cat's blood for months to years. (ncsu.edu)
Use of tick surveys and serosurveys to evaluate pet dogs as a sentinel species for emerging Lyme disease. (tamu.edu)

Organisms16

Diseases18

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes4

Information Science3

Health Care3

Geographicals5

Causes Lyme disease6

Borreliosis12

Diagnosis25

Bacterium5

Ixodes12

Ticks10

North America3

Carditis1

Spirochete5

Symptoms28

Infection11

Neuroborreliosis3

Treatment of Lyme Disease1

Erythema6

Causative agent of Lyme disease1

Patients with Early Lyme Disease2

Post-treatment Lyme disease syndrome1

Pathogen2

Arthritis3

Chronic Lyme di5

Canadian Lyme Disease Foundation1

Pedi Lyme Net1

20161

Increase in Lyme disease2

Majority of Lyme disease1

Early disseminated4

Surveillance7

Cause Lyme disease1

Antibodies1

Endemic areas3

Spirochetes2

Enzyme immunoassay1

Bacteria3

Neurological2

Humans2

Facial palsy1

Borrelia Burgdorferi4

Rash2

Persistent2

Clinical6

VlsE2

Syndrome3

Incidence4

Ehrlichiosis1

Diagnostic6

Syndromes2

Vector4

Serologic Tests2

Prevention7

Antibiotics4

America1

Infectious disease3

Cases17

Species4