• In conclusion, the present study demonstrated that SA inhibits the apoptosis of H9c2 cardiomyocytes following H/R injury via reduced activation of the p38MAPK and JNK signaling pathways. (spandidos-publications.com)
  • The results demonstrated that SA inhibited apoptosis signaling in H9c2 cardiomyocytes via downregulation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) signaling pathways following hypoxia/reoxygenation (H/R) injury. (spandidos-publications.com)
  • To investigate the effect of gambogic acid (GA) on apoptosis in the HT-29 human colon cancer cell line. (wjgnet.com)
  • It was found that ω-3 PUFA supplementation inhibited TBI-induced microglial activation and expression of inflammatory factors (TNF-α, IL-1β, IL-6, and IFN-γ), reduced brain edema, decreased neuronal apoptosis, and improved neurological functions after TBI. (biomedcentral.com)
  • Studies reported that caffeic acid might promote apoptosis in MG-63 osteosarcoma cells, however, the effect of caffeic acid treatment in preventing tumour mass formation has not been well elucidated, especially in MG-63 cells-induced nude mice in vivo . (inabj.org)
  • Caffeic acid induced apoptosis in MG63 osteosarcoma cells through activation of caspases. (inabj.org)
  • Wang T, Gong X, Jiang R, Li H, Du W, Kuang G. Ferulic acid inhibits proliferation and promotes apoptosis via blockage of PI3K/Akt pathway in osteosarcoma cell. (inabj.org)
  • Caspase inhibitor diminishes caffeic acid-induced apoptosis in osteosarcoma cells. (inabj.org)
  • In conclusion, the supplementation of MCTs combined with DHA could improve energy metabolism in the brain of APP/PS1 mice , thus decreasing nerve cell apoptosis and inhibiting the expression of Aß. (bvsalud.org)
  • Reuptake of glutamate in astrocytes, a critical mechanism involved in the maintenance of physiological excitatory amino acid neurotransmission, is inhibited by both arachidonic acid (AA) and reactive oxygen species (ROS), via incompletely defined molecular mechanisms. (unimi.it)
  • By inhibiting the COX pathway, aspirin diverts arachidonic acid metabolites to the LO pathway. (medscape.com)
  • Epoxyeicosatrienoic acids (EETs) are the products of arachidonic acid catalyzed by cytochrome P450 epoxygenase. (molcells.org)
  • It is involved in the conversion of arachidonic acid to prostaglandin H2, an important precursor of prostacyclin, which is expressed in inflammation. (wikipedia.org)
  • PTGS2 (COX-2), converts arachidonic acid (AA) to prostaglandin endoperoxide H2. (wikipedia.org)
  • The PTGS (COX) enzymes catalyze the conversion of arachidonic acid to prostaglandins in two steps. (wikipedia.org)
  • First, hydrogen is abstracted from carbon 13 of arachidonic acid, and then two molecules of oxygen are added by the PTGS2 (COX-2), giving PGG2. (wikipedia.org)
  • Figure 2) While metabolizing arachidonic acid primarily to PGG2, COX-2 also converts this fatty acid to small amounts of a racemic mixture of 15-Hydroxyicosatetraenoic acids (i.e., 15-HETEs) composed of ~22% 15(R)-HETE and ~78% 15(S)-HETE stereoisomers as well as a small amount of 11(R)-HETE. (wikipedia.org)
  • Furthermore, aspirin-treated COX-2 metabolizes arachidonic acid almost exclusively to 15(R)-HETE which product can be further metabolized to epi-lipoxins. (wikipedia.org)
  • The conversion of arachidonic acid to PGG2 can be shown as a series of radical reactions analogous to polyunsaturated fatty acid autoxidation. (wikipedia.org)
  • This is not consistent with the results of the isotope experiments of arachidonic acid oxygenation. (wikipedia.org)
  • This study was conducted to investigate the effect of all- trans retinoic acid (ATRA) on GIST cell lines. (biomedcentral.com)
  • This study aims to investigate the effects and mechanisms of all-trans retinoic acid (t-RA) on interleukin(IL)-1-induced production of several inflammatory mediators in human chondrocytes. (tmu.edu.tw)
  • Because the activation of the retinoic acid receptor has an inhibitory action on Cushing's disease progression, we analyzed the putative interaction of these two pathways. (unisr.it)
  • Indeed, retinoic acid induces both BMP-4 transcription and expression and its antiproliferative action is blocked in Smad-4dn- and noggin-transfected Att-20 cells that do not respond to BMP-4. (unisr.it)
  • Therefore, retinoic acid induces BMP-4, which participates in the antiproliferative effects of retinoic acid. (unisr.it)
  • Retinoic acid and transforming growth factor β (TGFβ) both inhibit Ito-cell [ 3 H]thymidine incorporation in serum-containing media. (wustl.edu)
  • Additionally, pre-treatment of Ito cells with retinoic acid and TGFβ blocked PDGF-induced cell proliferation. (wustl.edu)
  • TGFβ, but not retinoic acid, diminished PDGF-receptor and smooth-muscle α-actin abundance. (wustl.edu)
  • Davis, DH, Rapp, UR & Davidson, NO 1991, ' Retinoic acid and transforming growth factor β differentially inhibit platelet-derived-growth-factor-induced Ito-cell activation ', Biochemical Journal , vol. 278, no. 1, pp. 43-47. (wustl.edu)
  • Moreover, we uncovered a novel mechanism by which IL-37 suppressed tumor cell migration via its intracellular mature form (amino acids 46-218). (nature.com)
  • Structural comparison and biochemical analyses demonstrated that one single amino acid alteration between a corresponding valine and isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2. (proteopedia.org)
  • Single Amino Acid Alteration between Valine and Isoleucine Determines the Distinct Pyrabactin Selectivity by PYL1 and PYL2. (proteopedia.org)
  • Yuan X, Yin P, Hao Q, Yan C, Wang J, Yan N. Single Amino Acid Alteration between Valine and Isoleucine Determines the Distinct Pyrabactin Selectivity by PYL1 and PYL2. (proteopedia.org)
  • The amino acid composition is that of an acidic protein. (karger.com)
  • The enzyme confers a growth advantage to the bacterium, providing essential amino acid precursors by initiating the degradation of extracellular glutathione and glutamine. (unl.edu)
  • the membrane-binding domain consists of a series of amphipathic α helices with several hydrophobic amino acids exposed to a membrane monolayer. (wikipedia.org)
  • Nitric oxide is formed from the amino acid arginine by the enzyme nitric oxide synthase (NOS), simultaneously with citrulline. (medscape.com)
  • Arginine is a semi-essential amino acid, meaning that under healthy conditions, endogenous arginine production is adequate for metabolic needs, but under stress conditions, when arginine is excessively catabolized by the enzyme arginase, dietary intake of this amino acid is required. (medscape.com)
  • We further demonstrated that ω-3 PUFA supplementation inhibited HMGB1 nuclear translocation and secretion and decreased expression of HMGB1 in neurons and microglia in the lesioned areas. (biomedcentral.com)
  • Furthermore, ω-3 PUFA supplementation inhibited TBI-induced microglial activation and the subsequent inflammatory response by regulating HMGB1 nuclear translocation and secretion and also HMGB1-mediated activation of the TLR4/NF-κB signaling pathway, leading to neuroprotective effects. (biomedcentral.com)
  • Mechanistically, intracellular mature IL-37 directly bound to the CAAX motif in the C-terminal hypervariable region of Rac1, and then inhibited Rac1 membrane translocation and subsequent downstream signaling. (nature.com)
  • These data show that neither IkappaB degradation nor NF-kappaB nuclear translocation are inhibited by helenalin. (greenmedinfo.com)
  • IC injection of either human interleukin-1 beta, human interleukin-1 alpha, or rat interleukin-1 beta induced a dose-dependent inhibition of gastric acid output. (nih.gov)
  • These results show that IC interleukin-1 beta acts centrally to induce a long-lasting inhibition of gastric acid secretion, and this effect requires the integrity of prostaglandin pathways. (nih.gov)
  • PYL2_ARATH Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. (proteopedia.org)
  • Transplantation of cells releasing γ‐aminobutyric acid (GABA) could be used to counteract the imbalance between ex-citation and inhibition within epileptic neuronal networks. (lu.se)
  • LCA, GLCA, and TLCA sulfonation is catalyzed by human liver cytosol, and SULT2A1 followed the substrate inhibition model with comparable apparent K m values (≤1 µ M). Each of the SERMs inhibited LCA, GLCA, and TLCA sulfonation with varying potency and mode of enzyme inhibition. (aspetjournals.org)
  • Antagonistic effects of zinc and aluminum on lead inhibition of *-aminolevulinic acid dehydratase. (cdc.gov)
  • 1976. The in vitro effect of zinc on the inhibition of human *-aminolevulinic acid dehydratase by lead. (cdc.gov)
  • Therefore, the detrimental effect of ADMA might be inhibited by increasing the concentration of arginine or the concentration of its precursors, citrulline and glutamine, which would increase the arginine/ADMA ratio and thereby might reverse the competitive inhibition of NOS by ADMA. (medscape.com)
  • Intracellular mature form of IL-37, but not its extracellular form, markedly inhibited migration of multiple kinds of tumor cells through inhibiting Rac1 activation. (nature.com)
  • In the early reprogramming process, fatty acid oxidation upregulated oxidative phosphorylation and downregulated protein kinase C activity. (biomedcentral.com)
  • We demonstrated that fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C activity in the early stage of the reprogramming process. (biomedcentral.com)
  • It is a dietary plant phenol that has been shown to inhibit oxidative stress and chemical carcinogenesis. (cdc.gov)
  • A downregulation of FASN effectively inhibits the activity of "HER2-PI3K/Akt axis" and alters the malignant phenotype in colorectal cancer cells. (biomedcentral.com)
  • Moreover, ω-3 PUFA supplementation inhibited microglial activation and the subsequent inflammatory response by regulating HMGB1 and the TLR4/NF-κB signaling pathway. (biomedcentral.com)
  • Sandra F, Rizal MI, Wahid AHA, Andajana M, Celinna M. Caffeic acid induces intrinsic apoptotic pathway in mg-63 osteosarcoma cells through bid truncation and cytochrome c release. (inabj.org)
  • Inhibiting PARP-1 is lethal in a wide range of cancer cells that lack the homologous recombination repair (HR) pathway. (techscience.com)
  • These drugs must target a central step in NF-kappaB pathway, since they inhibit NF-kappaB induction by four different stimuli. (greenmedinfo.com)
  • However, the activated long-chain fatty acids, such as palmitoyl-CoA, cannot diffuse through the mitochondrial inner membrane. (biomedcentral.com)
  • Exposure of U937 cells to low concentrations of l-ascorbic acid (AA) is associated with a prompt cellular uptake and a further mitochondrial accumulation of the vitamin. (uniurb.it)
  • Under the same conditions, dehydroascorbic acid (DHA) uptake was followed by rapid reduction and accumulation of identical intracellular levels of AA, however, in the absence of significant mitochondrial uptake. (uniurb.it)
  • A shuttle system, composed of carnitine palmitoyltransferase (Cpt)1, translocase, and Cpt2, is required to transfer activated long-chain fatty acids into mitochondria. (biomedcentral.com)
  • The influence of recombinant human interleukins-1 beta and -1 alpha and rat interleukin-1 beta on gastric acid secretion was investigated in awake rats with pylorus ligation. (nih.gov)
  • IC injection of interleukin-1 beta inhibited vagally stimulated gastric acid secretion induced by IC injection of the stable thyrotropin-releasing hormone analogue RX 77368. (nih.gov)
  • Human interleukin-1 beta injected IV also inhibited gastric acid secretion, but the peripheral dose required to induce a significant effect was 10(3)-fold higher than when given centrally. (nih.gov)
  • OA significantly inhibited the expression of CD163, one of the phenotype markers of M2 macrophages, as well as suppressed the secretion of IL-10, one of the anti-inflammatory cytokines preferentially produced by M2 macrophages, thus suggesting that OA suppresses the M2 polarization of macrophages. (spandidos-publications.com)
  • Disruption in homeostasis of bile acids occurs when there is dysregulation in the synthesis/secretion, transport, or biotransformation of these endogenous substances ( Li and Apte, 2015 ). (aspetjournals.org)
  • It reflects the relative molecular mass or aromatic condensation degree of humic acid. (researchgate.net)
  • The E4/E6 data of humic acid/fulvic acid extracted by mechanochemical activation of peat are shown in Table 3. (researchgate.net)
  • The mechanochemical methods can increase the molecular condensation degree and molecular relative mass of humic acid, but reduce the molecular condensation degree and molecular relative mass of fulvic acid. (researchgate.net)
  • It is activated by mechanochemical method, and then humic acid and fulvic acid are extracted by alkali-soluble acid purification technology. (researchgate.net)
  • The results show that mechanochemical the method can improve the extraction rate of humic acid and fulvic acid in peat. (researchgate.net)
  • In a synthetic water, both oxidant decay and BrO3(-) formation were enhanced by CCPs, whereas the presence of humic acid (HA) significantly inhibited BrO3(-) formation due to its competition for HOBr to form Br-DBPs. (who.int)
  • By comparing the gene expression profiles of somatic cells, intermediate-phase cells, and iPSCs, we found that carnitine palmitoyltransferase (Cpt)1b, a rate-limiting enzyme in fatty acid oxidation, was significantly upregulated in the early stage of the reprogramming process. (biomedcentral.com)
  • The results suggested that water holding capacity, swelling kinetics and moisture uptake of humic acids were not influenced significantly by the amount of polar groups, but also by their spatial arrangement and distribution. (researchgate.net)
  • Warfarin prevents (inhibits) the action of the VKORC1 enzyme and slows the activation of clotting proteins and clot formation. (medlineplus.gov)
  • Individuals develop warfarin sensitivity because a lower warfarin dose is needed to inhibit the VKORC1 enzyme, as there is less functional enzyme that needs to be suppressed. (medlineplus.gov)
  • Dziedzic A, Kubina R, Kabała-Dzik A, Tanasiewicz M. Induction of cell cycle arrest and apoptotic response of head and neck squamous carcinoma cells (detroit 562) by caffeic acid and caffeic acid phenethyl ester derivative. (inabj.org)
  • Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA. (proteopedia.org)
  • PYL1 inhibits protein phosphatase type 2C upon binding of pyrabactin. (proteopedia.org)
  • Fatty acid synthase (FASN) is a homodimeric multienzymatic protein which can be divided into seven functional domains that are assembled into two homodimers [ 1 ]. (biomedcentral.com)
  • Supplementation of Medium-Chain Triglycerides Combined with Docosahexaenoic Acid Inhibits Amyloid Beta Protein Deposition by Improving Brain Glucose Metabolism in APP/PS1 Mice. (bvsalud.org)
  • Furthermore, OA inhibited the proliferation of U373 human glioblastoma cells, and the activation of signal transducer and activator of transcription-3 (STAT3) in both human macrophages and glioblastoma cells. (spandidos-publications.com)
  • These results indicate that OA suppresses the M2 polarization of macrophages and tumor cell proliferation by inhibiting STAT3 activation. (spandidos-publications.com)
  • Fujiwara Y, Komohara Y, Kudo R, Tsurushima K, Ohnishi K, Ikeda T and Takeya M: Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3. (spandidos-publications.com)
  • The proliferation activity, mortality of SH-SY5Y cells, adenosine triphosphate and pyruvic acid were measured. (ijpsonline.com)
  • abstract = "Sinusoidal Ito cells (stellate or fat-storing cells) undergo excessive cellular proliferation before the establishment and progression of hepatic fibrosis and cirrhosis. (wustl.edu)
  • Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3? (biomedcentral.com)
  • Early randomized controlled trials (RCTs) demonstrated the health benefits of omega-3 fatty acids (n-3), whereas recent RCTs were negative. (biomedcentral.com)
  • Finally, statins favor the metabolism of omega-6 fatty acids (n-6), which in turn inhibits n-3 and, contrary to n-3, they increase insulin resistance and the risk of diabetes. (biomedcentral.com)
  • Classic fatty acid metabolism involves the breakdown of fatty acids by beta-oxidation within the mitochondria. (biomedcentral.com)
  • Peroxidase activity was measured with 4 different hydrogen donors (ferulic acid, caffeic acid, pyrocatechol and pyrogallol). (tubitak.gov.tr)
  • Caffeic acid has been known to provide effective treatment but has less side effect for some cancer therapy. (inabj.org)
  • MG-63 cells were pre-treated with 0, 1, or 10 µg/mL caffeic acid, and 6 hours after pre-treatment, MG-63 cells were injected into subcutaneous space of mice to induce osteosarcoma. (inabj.org)
  • Another model was also created by subcutaneously injecting MG-63 cells to the back of mice, and after 48 days, the visible tumour mass was injected intra-tumour with 0 or 10 µg/mL caffeic acid every 7 days for 6 times. (inabj.org)
  • In pre-treated MG-63 cells-induced mice, volumes of the mass decreased in reverse with the dose of caffeic acid given. (inabj.org)
  • Meanwhile, the intra-tumour treatment of 10 µg/mL caffeic acid, even though not significant, was able to inhibit tumour mass formation. (inabj.org)
  • Results of caffeic acid pre-treatment and caffeic acid treatment in tumour mass of mice show that caffeic acid is able to inhibit the MG-63 cells formation. (inabj.org)
  • This suggests that caffeic acid can be a potential anti-cancer agent. (inabj.org)
  • By examining the effect of a c-jun N-terminal kinase (JNK) specific inhibitor, we showed that the suppression of JNK-AP-1 signaling was enough to inhibit IL-1-induced production of chemokines and activation of iNOS and COX-2 pathways. (tmu.edu.tw)
  • We have previously shown that helenalin and other sesquiterpene lactones selectively inhibit activation of the transcription factor NF-kappaB, a central mediator of the human immune response. (greenmedinfo.com)
  • Subchronic exposure to ellagic acid impairs cytotoxic T-cell function and suppresses humoral immunity in mice. (cdc.gov)
  • n-Butanol or isobutanol as a value-added fuel additive to inhibit microbial degradation of stored gasoline. (ornl.gov)
  • It has previously been reported that sesquiterpene lactones exert their effect by inhibiting degradation of IkappaB, the inhibitory subunit of NF-kappaB. (greenmedinfo.com)
  • Higher moisture uptake and water holding capacity were observed in humic acids, which were pre-wetted prior to crosslinking for at least 24 h. (researchgate.net)
  • We further provided evidence that IL-37 inhibited effectively tumor metastasis in vitro and in vivo . (nature.com)
  • Therefore, in the present comprehensive study, several antioxidative substances were assessed for their capacity to inhibit NET formation of primary human neutrophils in vitro. (uni-luebeck.de)
  • Erowid.org: Erowid Reference 1546 : Experimental analysis of the inhibitory action of lysergic acid diethylamide on cortical dendritic activity. (erowid.org)
  • Lysergic acid and mescaline had no effect. (erowid.org)
  • abstract = "Neutrophil extracellular traps (NETs) have been suggested to play a pathophysiological role in several autoimmune diseases. (uni-luebeck.de)
  • Girsang E, Lister INE, Ginting CN, Bethasari M, Amalia A, Widowati W. Comparison of antiaging and antioxidant activities of protocatechuic and ferulic acids. (inabj.org)
  • Ascorbic acid is an excellent antioxidant and may reduce organ damage by inhibiting the production of ROS. (mdpi.com)
  • This prospective observational study aimed to measure pre- and postoperative plasma ascorbic acid levels and examine their association with delirium. (mdpi.com)
  • As a consequence, TCR-induced LAT, PLC-γ, and AKT microcluster formation from aggregation of smaller nanocluster units, PI3K-AKT signaling axis, and calcium influx were potently inhibited by GML treatment. (nature.com)
  • Compared to the silyl ethers, silyl acetates are faster to hydrolyze, with the advantage that the released acetic acid is less aggressive. (wikipedia.org)
  • It contains acetic acid and nutrients such as B vitamins and vitamin C. (medlineplus.gov)
  • The addition of zoledronic acid to adjuvant letrozole therapy may protect against bone loss. (elsevierpure.com)
  • Patients and Methods: Patients receiving adjuvant letrozole were randomly assigned to receive either upfront or delayed-start zoledronic acid (4 mg intravenously every 6 months). (elsevierpure.com)
  • The delayed group received zoledronic acid when lumbar spine (LS) or total hip (TH) T score decreased to less than -2.0 or when a nontraumatic fracture occurred. (elsevierpure.com)
  • Conclusion: With 1 year of follow-up, results of the primary end point of the Zometa-Femara Adjuvant Synergy Trial (Z-FAST) indicate that upfront zoledronic acid therapy prevents bone loss in the LS in postmenopausal women receiving adjuvant letrozole for early-stage breast cancer. (elsevierpure.com)
  • zoledronic acid was the most commonly used medication. (bvsalud.org)
  • Neuraminidase inhibitors are a new class of antiviral drugs that inhibit influenza A and B viruses. (cdc.gov)
  • Protocatechuic acid (PCA), present in many fruits and vegetables, exhibited various biological activities. (nih.gov)
  • This inhibits cleavage of the sialyl-acid bond to the host receptor, thus the virus is unable to be released from infected host cells and spread to new cells. (who.int)
  • Some blood group A-active substances (secretor A saliva and hog gastric mucin A + H) have low potency to inhibit the agglutination. (karger.com)
  • Biofouling of gasoline can occur during fuel storage caused by bacteria and fungi that form a biofilm at a fuel/water interface and that produce organic acids and sulfides. (ornl.gov)
  • The work presented in this abstract focuses on the étude of the inhibitory activité of a naturel organic comprend (ascorbique acide ) for steel X60 (pipeline) in a marine envirement by gravemitric and electrochemical methodes. (easychair.org)
  • Various fatty acid oxidation-related metabolites were added during the reprogramming process. (biomedcentral.com)
  • Fatty acid oxidation-related metabolites were measured by liquid chromatography-mass spectrometry. (biomedcentral.com)
  • Maria Nowakowska , Mirosław Grebosz , Mirosława Smoluch , and Wiktor Tatara "Inhibiting Effect of β-Cyclodextrin on Thymine Dimerization Photosensitized by para -Aminobenzoic Acid," Photochemistry and Photobiology 75(2), 92-96, (1 February 2002). (bioone.org)
  • LSD inhibited or abolished the oxytocic effect of serotonin but not that of oxytocin on the isolated rat uterus. (erowid.org)
  • Fatty acid synthase (FASN) is frequently activated and overexpressed in human cancers, and plays a crucial role in the carcinogenesis of various cancers. (biomedcentral.com)
  • Syringic acid (SA), a naturally occur-ring O‑methy-lated trihydroxybenzoic acid monomer extracted from Dendrobium nobile Lindl. (spandidos-publications.com)
  • Glycerol Monolaurate (GML) is a naturally occurring fatty acid widely utilized in food, cosmetics, and homeopathic supplements. (nature.com)
  • COX-2 is naturally inhibited by calcitriol (the active form of Vitamin D). Both the peroxidase and PTGS activities are inactivated during catalysis by mechanism-based, first-order processes, which means that PGHS-2 peroxidase or PTGS activities fall to zero within 1-2 minutes, even in the presence of sufficient substrates. (wikipedia.org)
  • The 13-pro(S) -hydrogen is abstracted and dioxygen traps the pentadienyl radical at carbon 11. (wikipedia.org)
  • It is formed by intestinal bacterial 7 α -dehydroxylation of chenodeoxycholic acid and ursodeoxycholic acid ( Hofmann, 2004 ). (aspetjournals.org)
  • abstract = "Purpose: Treatment with aromatase inhibitors decreases bone mineral density (BMD) and may increase the risk of fractures in postmenopausal women with early-stage breast cancer. (elsevierpure.com)
  • The drug reduces bone resorption and inhibits the recruitment of osteoclasts. (bvsalud.org)
  • Asymmetric dimethylarginine (ADMA) can inhibit NO production by competing with arginine for NOS binding. (medscape.com)
  • The absence of endoperoxide-containing products derived from 10,10-difluoroarachidonic acid has been thought to indicate the importance of a C-10 carbocation in PGG2 synthesis. (wikipedia.org)
  • 1998. Interaction of blood lead and *-aminolevulinic acid dehydratase genotype on markers of heme synthesis and sperm production in lead smelter workers. (cdc.gov)
  • Medium-chain triglycerides (MCTs) and docosahexaenoic acid (DHA) positively improve brain glucose metabolism and decrease the expression of AD-related proteins . (bvsalud.org)
  • In this work, we tested the procedures to crosslink functional groups in polar domains of humic acids by using carbodiimide coupling and analyzed to which extent influenced the modification their hydration properties and stability. (researchgate.net)
  • Abstract Glioblastoma (GBM) is the most malignant form of glioma and is difficult to diagnose, leading to high mortality rates. (techscience.com)
  • Each entry includes the title of the article, author(s), Journal title, year (date of publication), volume number, issue number, number of pages, number of references, subject descriptors, geographic descriptors and abstract has been added and is searchable on the database on the Internet. (who.int)
  • We previously revealed that corosolic acid, a triterpenoid compound, inhibits the M2 polarization of human monocyte-derived macrophages (HMDM). (spandidos-publications.com)
  • We generated GABAergic interneuron precursors from human embryonic stem cells (hESCs) and grafted them in the hippocampi of rats developing chronic SRSs after kainic acid‐induced status epilepticus. (lu.se)