Abnormalities type metabolic syndrome is central obesity. Medical search. Frequent questions

Metabolic Syndrome (MetS) is a complex disorder that involves a cluster of metabolic abnormalities, including central obesity, insulin resistance, dyslipidemia, and hypertension. (hilarispublisher.com)
At this point, high insulin levels are often associated with central obesity, cholesterol abnormalities, and/or high blood pressure (hypertension). (diabeteshealthmatters.com)
Obesity has definitely become a growing problem, but a lot of anti-obesity educations, with fen-peen as the best example, have proven to have very damaging side-effects like lung hypertension and heart valve condition (Fen Peen, 2010). (directcurrentmusic.com)
In sub-Saharan Africa, hypertension followed by obesity was the commonly known cardiometabolic risk factors associated with the general adult population [ 8 ]. (hindawi.com)
Cardiovascular disease (CVD) risk factors such as obesity, hypertension, and dyslipidaemia are common in patients with DM, placing them at increased risk for cardiac events [ 10 , 11 ]. (hindawi.com)
We do agree that anybody with an A1c of 5.5% to 6.4% has glucose abnormalities, but we also know that many of them may already have diabetes based on glucose criteria," said Dr. Handelsman, adding that the organizations view metabolic syndrome, the cluster of such cardiovascular risk factors as hypertension and central obesity, as equivalent to prediabetes in terms of its associated risk of developing diabetes and cardiovascular disease. (acpinternist.org)
Metabolic syndrome (MetS) is characterized by a cluster of several metabolic and cardiovascular risk factors such as abdominal obesity, insulin resistance, atherogenic dyslipidemia, and hypertension [ 1 - 3 ]. (itmedicalteam.pl)
Assess patients with primary hypertriglyceridemia for other cardiovascular risk factors such as central obesity, hypertension, abnormalities of glucose metabolism, and liver dysfunction. (guidelinecentral.com)
Besides effective control of blood pressure in patients with hypertension, third-generation beta-blockers such as nebivolol offer additional benefits for central hemodynamics and neutral or beneficial effects on metabolism. (nih.gov)
The present article will provide a systematic analysis of the pathophysiological links among hypertension, insulin resistance, and metabolic syndrome. (nih.gov)
Ce syndrome se caractérise par l'association d'anomalies incluant une résistance à l'insuline, un hyper-insulinisme, une intolérance au glucose ou un diabète de type 2, une hypertension artérielle et des troubles du métabolisme lipidique et de la coagulation. (erudit.org)
It is characterized by a cluster of risk factors of atherosclerosis including insulin resistance, hyperinsulinemia, impaired glucose tolerance or type 2 diabetes, hypertension, dyslipidemia, and coagulation abnormalities. (erudit.org)
Primary care providers should be alert to the importance of screening patients with hypertension for metabolic syndrome to prevent and manage these combined conditions. (who.int)
Patients were oriented to the objec- sity lipoprotein (HDL) cholesterol], This clinic provides primary care to a tives of the study and their consent was hypertension, central obesity and ele- socially diversified group of patients secured. (who.int)
Metabolic Syndrome" (MetS), refers to the clustering of abdominal obesity, impaired glucose tolerance, hypertriglyceridemia, diminished high density lipoprotein (HDL) cholesterol, and/or hypertension in an individual. (kauveryhospital.com)
The risk of serious health consequences such as type 2 diabetes, coronary heart disease, hypertension, dyslipidaemia, albuminuria and a wide range of other conditions increases with BMI. (slideplayer.com)
Methods: Metabolic syndrome is ≥3 of the following: hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol, hypertension, abdominal obesity, and high serum glucose. (natap.org)
The present study was designed to estimate the prevalence of dyslipidemia and hypertension based on the National Cholesterol Educational Programme Adult Treatment Panel III definition of metabolic syndrome (MetS). (ophrp.org)
Dyslipidemia and hypertension were determined in type 2 diabetic patients with MetS as per National Cholesterol Educational Programme Adult Treatment Panel III criteria. (ophrp.org)
Notable increase in the dyslipidemia (64.1%) and hypertension (49%) in type 2 diabetic patients were seen. (ophrp.org)
These meta-analyses consistently show that depression increases the risk of overall mortality (RR = 1.81) and the development of cardiovascular-related outcomes, such as heart disease (RR = 1.81), diabetes (RR = 1.60), hypertension (RR = 1.42), stroke (RR = 1.34) and obesity (RR = 1.58). (biomedcentral.com)
Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess abdominal fat), hypertension, abnormal fasting plasma glucose or insulin resistance, and dyslipidemia. (merckmanuals.com)
It is known that excess body fat is associated with heart disease, diabetes, hypertension, and certain types of cancer 1-3 . (bvsalud.org)
Une recherche documentaire a été effectuée dans PubMed de 1980 à 2021 en utilisant diverses combinaisons de termes MeSH comme tabac, diabète, hypertension, dyslipidémie, trouble dépressif majeur, trouble bipolaire, schizophrénie. (bvsalud.org)

Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). (wikipedia.org)
Metabolic syndrome is defined by central obesity, increased systolic and diastolic blood pressure (BP), decreased high-density lipoprotein cholesterol (HDL-C), increased serum triglycerides (TG), and elevated fasting blood glucose (FBG). (biomedcentral.com)
Diabetes mellitus was the most frequent component of metabolic syndrome in males, while low serum high-density lipoprotein cholesterol and high waist circumference ranked first and second in females. (who.int)
A low plasma HDL cholesterol level (HDL, high-density lipoprotein) is a common lipid abnormality in patients affected by premature CHD and also a component of the metabolic syndrome, a cluster of risk factors for atherosclerosis associated with central obesity. (oulu.fi)
Participants were designated as having metabolic syndrome if they met criteria for 3 of 5 variables: 1) high blood pressure, 2) low high-density lipoprotein cholesterol level, 3) high fasting blood glucose level, 4) high waist circumference, and 5) high triglyceride level. (cdc.gov)
Clinical diagnosis is made on the basis of the presence of 3 of 5 conditions: 1) high triglyceride level, 2) low high-density lipoprotein (HDL) cholesterol level, 3) high fasting blood glucose level, 4) presence of central obesity (ie, high waist circumference), and 5) high blood pressure ( 1 ). (cdc.gov)

Insulin resistance, metabolic syndrome, and prediabetes are closely related to one another and have overlapping aspects. (wikipedia.org)
Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes. (wikipedia.org)
There is debate regarding whether obesity or insulin resistance is the cause of the metabolic syndrome or if they are consequences of a more far-reaching metabolic derangement. (wikipedia.org)
Rather than total adiposity, the core clinical component of the syndrome is visceral and/or ectopic fat (i.e., fat in organs not designed for fat storage) whereas the principal metabolic abnormality is insulin resistance. (wikipedia.org)
Central obesity is a key feature of the syndrome, as both a sign and a cause, in that the increasing adiposity often reflected in high waist circumference may both result from and contribute to insulin resistance. (wikipedia.org)
However, despite the importance of obesity, affected people who are of normal weight may also be insulin-resistant and have the syndrome. (wikipedia.org)
Insulin resistance precedes the development of type 2 diabetes, sometimes by years. (diabeteshealthmatters.com)
In individuals who will ultimately develop type 2 diabetes, it has been shown that blood glucose and insulin levels are normal for many years, until at some point in time, insulin resistance develops. (diabeteshealthmatters.com)
Insulin resistance can be noted long before type 2 diabetes develops. (diabeteshealthmatters.com)
Individuals reluctant or unable to see a health care practitioner regularly often seek medical attention when they have already developed type 2 diabetes and insulin resistance. (diabeteshealthmatters.com)
Few studies have reported the adherence to and efficacy of continuous glucose monitoring (CGM) for improving diabetes management in insulin-treated older adults with type 2 diabetes mellitus (T2DM). (biomedcentral.com)
Metabolic Syndrome (MetS) and Type 2 diabetes (T2D) are clinical conditions involving the impaired uptake and utilization of glucose, altered lipid metabolism, and the disruption of the metabolic signaling pathways that regulate insulin secretion from pancreas ( 1 ). (frontiersin.org)
In Type 1 diabetes , the cells that should produce insulin have been destroyed. (diabetesinfo.org.nz)
At the moment, people with Type 1 diabetes face daily insulin injections for the remainder of their lifetime. (diabetesinfo.org.nz)
In Type 2 diabetes , which is far more common, the body doesn't respond properly to insulin, and often not enough insulin is produced. (diabetesinfo.org.nz)
Many people with Type 2 diabetes eventually go on to need insulin injections. (diabetesinfo.org.nz)
Type 1 diabetes is often referred to as insulin-dependent (IDDM) or juvenile-onset diabetes. (diabetesinfo.org.nz)
Type 2 diabetes is often referred to as non-insulin dependent (NIDDM) or maturity-onset diabetes. (diabetesinfo.org.nz)
these hormones may reduce insulin action in the mother's body, causing insulin resistance (similar to Type 2 diabetes). (diabetesinfo.org.nz)
GW-501516 SARM studies were famously pioneered by world-class biologist Ronald Evans at the Salk Institute in La Jolla, CA. He regarded GW-501516 as the long sought-after molecule to confer metabolic protection, calling it "a multifaceted therapeutic for metabolic syndrome with the potential to control weight gain, enhance physical endurance, improve insulin sensitivity, and ameliorate atherosclerosis" [1]. (umbrellalabs.is)
Aniamls fed GW-501516 along with a calorie-dense diet showed reducded obesity and improved insulin resistance, effects that were accompanied by enhanced metabolic rate and fatty acid β-oxidation, proliferation of mitochondria (the powerhouses of cells), and a significant reduction of lipid fat droplets in skeletal muscles. (umbrellalabs.is)
Its pathophysiology is likely to involve insulin resistance at the level of both skeletal muscle and visceral adipose tissue and altered fluxes of metabolic substrates between these tissues that in turn impair liver metabolism. (erudit.org)
It is now known that Central/Visceral Obesity with its Insulin Resistance and or Hyperinsulinemia is central in the pathogenesis of MetS. (kauveryhospital.com)
The metabolic counterpart is excess lipolysis driving fatty acid levels, cathecholamine-induced peripheral, hepatic insulin resistance and fatty liver disease. (kauveryhospital.com)
This preferential lipid fuel usage and associated hyperglycemia with insulin resistance lead to a combined Gluco-lipotoxicity and higher free radical generation mediated cardiac injury leading to heart failure as a final sequel in obesity. (kauveryhospital.com)
Nonalcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are multidisciplinary liver diseases that often accompany type 2 diabetes or metabolic syndrome, which are characterized by insulin resistance. (hindawi.com)
Accordingly, insulin sensitizers, antioxidative agents, Niemann-Pick C1-like 1 (NPC1L1) inhibitors, RAS blockers, and drugs that target the central nervous system may represent candidate pharmacotherapies for NAFLD and possibly NASH. (hindawi.com)
The metabolic abnormalities of type 2 diabetes, including hyperglycemia, dyslipidemia, and insulin resistance, activate the Janus kinases/signal transducer and activator of transcription (JAK/STAT) signaling pathway, a major intracellular inflammatory cascade that transmits the intracellular signaling to the nucleus ( 2 ), promoting inflammatory response, inducing insulin resistance ( 3 ), and accelerating the development of cardiovascular complications ( 4 ). (diabetesjournals.org)
That's when he told me that he was an insulin-dependent type 2 diabetic. (thenutritiondebate.com)
Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. (biomedcentral.com)
Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance (IR), is an increasing problem in affluent societies. (biomedcentral.com)
To test the role of the liver, specific and exclusive deletion of hepatic CB 1 receptor resulted in a rescue of the dyslipidemic effects of glucocorticoid exposure, while not affecting the obesity phenotype or the elevations in insulin and leptin. (iasvn.org)
Primary risk factor of metabolic syndrome is insulin resistance which can either be genetic or environmental (nutrient deficiency, excess caloric intake or lack of physical activity). (blogspot.com)
Clinical studies suggest that type 2 diabetes mellitus (T2DM) is a risk factor for cognitive decline and dementia, and have found evidence that insulin resistance (IR) occurs in the brain of patients with T2DM and Alzheimer disease (AD). (nature.com)
Clinical studies suggest a link between type 2 diabetes mellitus (T2DM) and insulin resistance (IR) and cognitive dysfunction, but there are significant gaps in our knowledge of the mechanisms underlying this relationship. (nature.com)
Replacement of GH in adults with GHD markedly reduces central obesity and substantially reduces total cholesterol levels but has produced little change in other risk factors, particularly insulin resistance and dyslipidemia. (medscape.com)
Insulin resistance and obesity are often present. (merckmanuals.com)

Metabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. (molvis.org)
The alarming increase in the prevalence of obesity or MetS is likely to further exacerbate the risk for ophthalmic abnormalities associated with obesity. (molvis.org)
The relationship between tea and coffee consumption and mortality among patients with metabolic syndrome (MetS) remains barely explored. (biomedcentral.com)
The aim of this study was to evaluate acylated ghrelin and obestatin levels and their ratio in obese and normal-weight children and adolescents, and their association with metabolic syndrome (MetS) parameters. (mdpi.com)
Explain the relationship between metabolic syndrome (MetS) and periodontal disease, and a potential assessment tool for MetS risk. (dimensionsofdentalhygiene.com)
Background: Warning signs of metabolic syndrome (MetS) can appear during childhood. (itmedicalteam.pl)
Early detection and treatment of MetS is likely to reduce morbidity and mortality in adulthood and help to keep to minimum the global burden of cardiovascular diseases and type II diabetes. (itmedicalteam.pl)
Conclusions: The prevalence of MetS among overweight and obese Palestinian schoolchildren is high with dyslipidemia being the most common MetS abnormality. (itmedicalteam.pl)
MetS is consistently associated with high Cardio-Vascular event risk and high incidence of Type 2 Diabetes mellitus. (kauveryhospital.com)
It is the pathophysiologic aspects of obesity coupled with MetS that leads to changes in hemodynamics, atherosclerosis and calcification, myocardial metabolism, microvascular dysfunction that culminates in myocardial infarction and heart failure. (kauveryhospital.com)
Over the past two decades, the prevalence of metabolic abnormalities such as type 2 diabetes and metabolic syndrome (MetS) has been increasing worldwide together with the escalating obesity pandemic [ 1 - 3 ]. (hindawi.com)
Since NAFLD is closely associated with obesity, diabetes, and MetS, it is unknown whether the relationship between NAFLD and all-cause mortality and cardiovascular death, if any, is independent of cardiometabolic risk factors (Figure 1 ) such as MetS and type 2 diabetes. (hindawi.com)
The severity of the metabolic syndrome (MetS) is significantly associated with future coronary heart disease (CHD) among individuals without baseline Type 2 diabetes. (biomedcentral.com)
To assess for differences in MetS severity by timing of Type 2 diabetes diagnosis and to assess for associations between MetS severity and future CHD among individuals with diabetes. (biomedcentral.com)
MetS severity appears to provide an estimate of metabolic disarray in the setting of diabetes and is predictive of future CHD events beyond HbA1c. (biomedcentral.com)
As such, it is unclear among individuals with diabetes whether assessing MetS severity would be an accurate means of tracking metabolic abnormalities over time and predicting future CHD. (biomedcentral.com)
For the no-glucose score, it is possible that any CHD risk related to abnormalities in the other four MetS components would be inconsequential relative to the risk conferred by the degree of diabetes control. (biomedcentral.com)
Effective treatment of MetS components is required to reduce cardiovascular risk in diabetes mellitus hence accurate and early diagnosis to induce effective treatment of MetS in Indian population will be pivotal in the prevention of cardiovascular disease and type 2 diabetes. (ophrp.org)
Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. (biomedcentral.com)

HPA-axis dysfunction may explain the reported risk indication of abdominal obesity to cardiovascular disease (CVD), type 2 diabetes and stroke. (wikipedia.org)
Through this article, we will better define abdominal obesity is and discuss treatment solutions to combat it. (gurze.com)
Abdominal obesity results in an enlarged belly. (gurze.com)
To identify abdominal obesity, BMI monitoring must be followed by waist circumference measurement. (gurze.com)
Marked obesity in the abdominal area can have several causes. (gurze.com)
Abdominal obesity can make life very disabling for those who suffer from it. (gurze.com)
This has led to an increasing evidence for abdominal obesity indices such as waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) as predictors of CVD [ 16 , 17 ]. (hindawi.com)
Waist circumference was anddiabetesthatincludeshyperten- familypracticeclinicattheUniversity measuredusingasteelmeasuringtape, sion,glucoseintolerance,dyslipidaemia ofJordanHospitalwerescreenedfor atthepointhalfwaybetweenthelower and abdominal obesity. (who.int)
31 The presence of abdominal obesity is more highly correlated with the metabolic risk factors than is an elevated BMI. (slideplayer.com)
Evidence linking depression to metabolic syndrome abnormalities indicates that depression is especially associated with its obesity-related components (for example, abdominal obesity and dyslipidemia). (biomedcentral.com)
Central or abdominal obesity happens when someone consumes more than their recommended caloric intake and doesn't incorporate enough physical activity into their daily life. (naturalwellbeing.com)
Individuals who suspect they're at risk for abdominal obesity should consult their doctor first. (naturalwellbeing.com)

The prevalence of metabolic syndrome and central obesity increased with age, with the highest rates seen among middle-aged and older adults [ 5 ]. (biomedcentral.com)
ABSTRACT Objective: to evaluate the prevalence of metabolic syndrome and associated factors in nursing professionals working in oncology. (bvsalud.org)
The baseline prevalence of metabolic syndrome in the NFHL study (n = 477) was compared to that in the NHANES (n = 1876), adjusted for age, race, gender, poverty, exercise, and diet. (natap.org)
The prevalence of metabolic syndrome was significantly lower in HAART and non-HAART users compared with NHANES participants unadjusted for body mass index (BMI). (natap.org)
To our knowledge, this is one of the first large studies of the incidence and prevalence of metabolic syndrome in HIV. (natap.org)
The most current data show that a 9.2% prevalence of metabolic syndrome from 1988 through 1994 increased to 12.7% from 1999 through 2000 ( 6 ). (cdc.gov)

More and more doctors prefer to use waist circumference measurements to determine the forms of obesity. (gurze.com)
The differentiation ratio between android obesity and gynoid obesity can also be made by measuring the ratio of waist to hip circumference. (gurze.com)
The western dietary pattern, obesity, high body fat, high waist or hip circumference, and high waist-to-hip ratio were significantly associated with increased odds ratios of high CRP and NLR in both genders. (biomedcentral.com)
Obesity defined by body mass index (BMI) and waist circumference was associated with inflammation [ 12 ]. (biomedcentral.com)
The new IDF consensus definition of the metabolic syndrome stipulates the following as a pre-requisite for a diagnosis of metabolic syndrome: ≥ 80 cm for European women ≥ 94 cm for European men Waist circumference is calculated by comfortably measuring the waist halfway between the bottom of the rib cage and the top of the pelvis. (slideplayer.com)
We examined the utility of body mass index (BMI) and waist circumference to identify metabolic syndrome in adolescent girls. (cdc.gov)
We predicted the likelihood of the presence of metabolic syndrome by using previously established cutpoints of BMI and waist circumference. (cdc.gov)
001). Girls with a waist circumference above the cutpoint were more likely than girls with a waist circumference below the cutpoint to have metabolic syndrome ( P = .002). (cdc.gov)
Stepwise regression showed that only waist circumference significantly predicted metabolic syndrome. (cdc.gov)
Waist circumference was a better predictor of metabolic syndrome than was BMI in our study sample of predominantly African American female adolescents living in an urban area. (cdc.gov)

Raised fasting blood glucose (at least 100 mg/dL) or previously diagnosed type 2 diabetes. (medscape.com)
Hypoglycemia is a barrier to optimal glucose control in the treatment of both type 1 (T1DM) and type 2 diabetes mellitus (T2DM). (biomedcentral.com)
Patients with higher-than-normal blood glucose levels are at increased risk for developing type 2 diabetes, cardiovascular disease, and stroke, according to the CDC. (acpinternist.org)
As of 2015, the U.S. Preventive Services Task Force (USPSTF) recommends screening for glucose abnormalities in adults ages 40 to 70 with overweight or obesity as part of cardiovascular risk assessment, a B-grade recommendation. (acpinternist.org)
The myocardium is capable of sustained function using fuels not limited to acetate, glucose or long-chain fatty acids - it is indeed a metabolic omnivore. (kauveryhospital.com)
Specific antiretroviral therapies are known to affect individual components of the metabolic syndrome adversely, such as increasing triglycerides (lopinavir/ritonavir,32 nevirapine,33 and nelfinavir33) and increasing fasting glucose (indinavir34 and lopinavir/ritonavir35). (natap.org)
One potential benefit of fenugreek is improving elevated blood glucose and lipid levels associated with chronic conditions such as diabetes and obesity. (lww.com)

However, warning signs of metabolic syndrome can appear during childhood [ 3 ]. (itmedicalteam.pl)
Paying attention to the signs of metabolic syndrome can help you turn your health around to protect your body later in life. (naturalwellbeing.com)

Research shows that Western diet habits are a factor in development of metabolic syndrome, with high consumption of food that is not biochemically suited to humans. (wikipedia.org)
First, high viral load did not predict development of metabolic syndrome. (natap.org)

Such a risk was mainly caused by the excess presence of hypertriglyceridemia and central obesity. (afpm.org.my)
Most with metabolic syndrome (77%) had low HDL and hypertriglyceridemia plus ≥1 additional abnormality. (natap.org)

Our family medicine clinic is a hos- study period, the number of selected pital-affiliated clinic located in Jordan patients totalled 730 (281 males and The metabolic syndrome is a cluster- University Hospital (the main teaching 449 females). (who.int)

Clustering of metabolic abnormalities had significantly increased by increasing body mass index and waist circumferences, and with decreased HDL and elevated triglyceride. (itmedicalteam.pl)
After adjustment for covariates including age, cigarette smoking, and physical activity, the -866A/A genotype was associated with higher waist-to-hip ratio as compared with the wild-type genotype in Chinese and Indian men (p = 0.018 and p = 0.046, respectively). (afpm.org.my)

Abnormalities in intracellular Ca 2+ handling due to sub-cellular/receptor level dysfunction are implicated. (kauveryhospital.com)
This syndrome involves anovulation or ovulatory dysfunction and androgen excess of unclear etiology. (merckmanuals.com)
expertise to identify causal links between obesity and metabolic dysfunction in nutrition, metabolic factors, and cancer. (who.int)

Metabolic syndrome can lead to several serious and chronic complications, including type-2 diabetes, cardiovascular diseases, stroke, kidney disease and nonalcoholic fatty liver disease. (wikipedia.org)
To evaluate the association of CGM parameters and HbA1c with diabetes complications in patients with Type 1 Diabetes (T1D). (biomedcentral.com)
Childhood obesity is a significant health problem and associated with several metabolic and cardiovascular complications [ 6 - 8 ]. (itmedicalteam.pl)
Polycystic ovary syndrome has several significant potential complications. (merckmanuals.com)
In the United States, obesity and its complications cause as many as 300,000 premature deaths each year, making it second only to cigarette smoking as a preventable cause of death. (msdmanuals.com)
screening for comorbidities of obesity should be applied in a hierarchal, logical manner for early identification before more serious complications result. (medscape.com)
Notre objectif était de décrire le profil clinico-biologique chez une population de diabé tique type 2 et d'étudier la relation entre l'équilibre glycémique et les anomalies lipidiques avec les complications micro et macroangiopathiques. (bvsalud.org)

Raised triglycerides (at least 150 mg/dL) or specific treatment for this lipid abnormality. (medscape.com)

38 In a multicentered, randomized controlled trial that studied the effects of periodontal treatment on secondary prevention of cardiovascular disease, Offenbacher et al 39 demonstrated that obesity may exert such a dominant influence that when obese individuals undergo periodontal therapy, its presence may nullify the effects of periodontal treatment on high-sensitivity C-reactive protein (hs-CRP), a sensitive marker of systemic inflammation. (dimensionsofdentalhygiene.com)

001). Although improved and persistent metabolic syndrome were both significantly associated with total WOMAC score, neither was significantly associated with knee pain after adjustment for age, sex, and BMI. (medscape.com)
however, this may vary significantly by age, dietary habits, gender, and even among participants with morbid obesity [ 9 ]. (hindawi.com)
Also, the microvascular tone and microvascular density are significantly impacted by obesity. (kauveryhospital.com)
We used stepwise regression analysis to determine whether anthropometric measurements significantly predicted metabolic syndrome. (cdc.gov)

The impaired cholesterol efflux to HDL2 fraction was primarily in conjunction with the metabolic syndrome. (oulu.fi)
Other therapies have been associated with improvements in metabolic profiles, such as increases in HDL cholesterol (nevirapine and nelfinavir).33 In our cohort, lopinavir/ritonavir users had a higher risk of developing metabolic syndrome. (natap.org)
Assessment of metabolic syndrome was done by International Diabetic Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. (biomedcentral.com)
Patients are diagnosed with metabolic syndrome when they exhibit multiple factors, including abnormally high blood pressure, high blood sugar, high cholesterol and obesity, among others. (naturalwellbeing.com)
Metabolic syndrome often results in men with less than 40 milligrams of cholesterol per deciliter and less than 50 milligrams for women. (naturalwellbeing.com)
It is also used for obesity, altitude sickness, aging skin, high levels of cholesterol or other fats in the blood, and many other purposes, but there is no good scientific evidence to support many of these other uses. (medlineplus.gov)

ABSTRACT Metabolic syndrome is being reported more frequently in the Eastern Mediterranean region. (who.int)
ABSTRACT This study assessed the prevalence of the metabolic syndrome, and its components, as defined by Adult Treatment Panel III criteria in Jordanian patients attending a family practice clinic for management of cardiovascular risk factors. (who.int)

The molecular mechanisms underlying this obesity-induced cardiac phenotype disorder are not well understood. (kauveryhospital.com)
Similarly, a neutral, peripherally restricted CB 1 receptor antagonist (AM6545) was able to attenuate the metabolic phenotype caused by chronic corticosterone, suggesting a peripheral mechanism for these effects. (iasvn.org)

citation needed] Recent research indicates prolonged chronic stress can contribute to metabolic syndrome by disrupting the hormonal balance of the hypothalamic-pituitary-adrenal axis (HPA-axis). (wikipedia.org)
We excluded participants with diabetes, metabolic syndrome, chronic diseases, and those who had changed food habits in the previous 3 months. (frontiersin.org)
There is a strong rationale for implementing a risk assessment model that considers patients' cumulative inflammatory burden, which may be amplified by obesity and chronic infection from periodontal disease. (dimensionsofdentalhygiene.com)
Chronic low-grade inflammation is an important pathogenic factor in the development of type 2 diabetes and cardiovascular diseases ( 1 ). (diabetesjournals.org)
In contrast, the relation between increasing viral load and metabolic syndrome does not seem to be mediated by general inflammation caused by chronic infection for 2 reasons. (natap.org)
Brand new research published in the last few weeks reveals important information for people with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Fibromyalgia (FM). (wellnessresources.com)
Obesity is a chronic, multifactorial, relapsing disorder characterized by excess body weight and defined as a body mass index (BMI) of ≥ 30 kg/m2. (msdmanuals.com)
The ABOM stresses obesity be considered a chronic disorder that requires lifelong treatment and follow-up. (msdmanuals.com)

Fat distribution can be influenced by the sex and age of the person with metabolic disorders. (gurze.com)
25% body fat in men) may foretell the presence of metabolic disorders, or downstream precipitation of incident diabetes, cardiovascular disease, and other inflammatory-driven conditions. (dimensionsofdentalhygiene.com)
Acquired or inherited defects associated to environmental factors in any part of this system can lead to metabolic disorders such as the syndrome X which is presently a frequent syndrome in industrialized countries. (erudit.org)
In addition, if necessary, specific treatment of the metabolic disorders is required. (erudit.org)
Therefore, effective treatment of type 2 diabetes and metabolic syndrome should target not only the cardiometabolic abnormalities, but also the associated liver disorders. (hindawi.com)
Notably, NAFLD appears to be an early predictor of metabolic disorders, particularly among normal-weight individuals [ 7 ]. (hindawi.com)
Obesity and associated metabolic disorders (e.g., cardiovascular disease and type 2 diabetes) are major public health concerns. (iasvn.org)

Because data on Brazilian women with polycystic ovary syndrome (PCOS) are still scarce, a nation-wide collaborative study was designed to determine the prevalence of metabolic and reproductive abnormalities and the presence of anxiety and depression in Brazilian women with PCOS. (bmj.com)

About 4790 deaths recorded in the same year aside the many undiagnosed cases in Africa, type II diabetes mellitus (T2DM) accounted for 90-95% of all diagnosed cases [ 3 , 4 ]. (hindawi.com)
Irisin plays a key role in metabolic diseases, including type 2 diabetes mellitus (T2DM). (biomedcentral.com)
The Ala allele of the common Pro12Ala polymorphism in the isoform PPAR-γ2 is at the center of many controversies because in some populations, it has been observed to be associated with T2DM or obesity but, not in others. (biomedcentral.com)
The aim of this study was to investigate the association of Pro12Ala polymorphism in the PPAR-γ2 gene with susceptibility to obesity or T2DM in a Cameroonian population. (biomedcentral.com)
PPAR-γ2 Pro12Ala gene polymorphism may not be associated with obesity and T2DM. (biomedcentral.com)
These results suggest that, PPAR-γ2 is unlikely a major gene for obesity or T2DM in the study population. (biomedcentral.com)
The prevalence of obesity and T2DM is increasing dramatically and WHO reports that more than 500 million people are obese [ 1 ] and 387 million have diabetes [ 2 ]. (biomedcentral.com)
Obesity and T2DM are called "multifactorial" or "complex" diseases because, they depend on multiple genetic factors as well as environment. (biomedcentral.com)
Some genes are thought to be involved in the development of T2DM and obesity amongst which, the peroxisome proliferator activated receptor gamma (PPAR-γ) gene. (biomedcentral.com)
Knowledge of genetic polymorphisms that allow accurate quantification of T2DM and obesity risk will allow the development of complex models with diagnostic and prognostic. (biomedcentral.com)
This preliminary study aimed to investigate the association of Pro12Ala with T2DM and obesity in a Cameroonian population. (biomedcentral.com)

The pathogenic role played in the syndrome by the excessive expansion of adipose tissue occurring under sustained overeating, and its resulting lipotoxicity was reviewed by Vidal-Puig. (wikipedia.org)
A polymorphism in the promoter region of uncoupling protein 2 gene -866G/A has been associated with its expression levels in adipose tissue, the risk of obesity, and metabolic abnormalities. (afpm.org.my)

These data further our understanding of the role of endocannabinoid signaling to promote not only diet-induced, but also, hormonal-mediated obesity and support the argument that peripheral blockade of endocannabinoid signaling could be a potential treatment for obese conditions. (iasvn.org)
Causes of obesity are multifactorial and include genetic predisposition and behavioral, metabolic, and hormonal influences. (msdmanuals.com)

Together, these data indicate that glucocorticoids recruit peripheral endocannabinoid signaling to promote metabolic dysregulation, with hepatic endocannabinoid signaling being especially important for changes in lipid metabolism. (iasvn.org)

The IDF consensus worldwide definition of the metabolic syndrome. (gurze.com)

There is usually a clear pattern of dominant inheritance in MODY patients and investigation of this genetically defined subgroup of Type 2 diabetes has so far revealed more than six different genetic causes. (diabetesinfo.org.nz)
Unfortunately, some adults are predisposed to metabolic syndrome due to their genetic makeup. (naturalwellbeing.com)
Pediatric obesity has its basis in genetic susceptibilities influenced by a permissive environment starting in utero and extending through childhood and adolescence. (medscape.com)
Genetic screening for rare syndromes is indicated only in the presence of specific historical or physical features. (medscape.com)
Despite a significant increase in research on pediatric obesity since the initial publication of these guidelines 8 years ago, further study is needed of the genetic and biological factors that increase the risk of weight gain and influence the response to therapeutic interventions. (medscape.com)
Clinical and genetic characterization of familial central precocious puberty. (cdc.gov)
Understanding the phenotypic spectrum and family experiences of XYY syndrome: Important considerations for genetic counseling. (cdc.gov)

Obesity in Adolescents Obesity is now twice as common among adolescents than it was 30 years ago and is one of the most common reasons for visits to adolescent clinics. (msdmanuals.com)
to evaluate the prevalence of obesity and the body fat topography in children and adolescents from both sexes aged 6 to 19 years old with Down syndrome, residents in the city of Campinas, São Paulo. (bvsalud.org)
the assessment of the prevalence of obesity and subcutaneous fat topography are important resources to support researchers, and practitioners who work directly on improving the quality of life of children and adolescents with Down syndrome. (bvsalud.org)
In children and adolescents with Down syndrome (DS), high obesity levels were also recorded from the 80's to the present days 5,6 . (bvsalud.org)
Thus, care with the obesity control in children and adolescents with DS should be redoubled, because excess body fat is one of the characteristics of the syndrome, which can seriously contribute to the increased incidence of several diseases. (bvsalud.org)
Therefore, the study of the body fat behavior through the assessment of the body composition, occupies an important space in the identification of the levels of obesity in various populations, especially in children and adolescents with Down syndrome. (bvsalud.org)
Pediatric obesity remains an ongoing serious international health concern affecting ~17% of US children and adolescents, threatening their adult health and longevity. (medscape.com)
Adolescents undergoing lifestyle therapy, medication regimens, or bariatric surgery for obesity will need cohesive planning to help them effectively transition to adult care, with continued necessary monitoring, support, and intervention. (medscape.com)
Metabolic syndrome is increasing among adolescents. (cdc.gov)

Of total participants, 18% met the criteria for metabolic syndrome. (cdc.gov)

To supplement existing evidence on the association between metabolic syndrome and joint pain in older adults, the researchers investigated the association in middle-aged adults over a 10- to 13-year period. (medscape.com)
The objective of the study was to determine the association of dietary patterns, anthropometric measurements, and metabolic parameters with inflammatory markers in middle-aged and older adults with metabolic syndrome in Taiwan. (biomedcentral.com)
It is becoming evident that a proportion of adults may have a slowly evolving kind of Type 1 diabetes, which is characterised by the presence of autoantibodies. (diabetesinfo.org.nz)
Objective: To determine the incidence and risk factors for metabolic syndrome in HIV-infected adults in the Nutrition for Healthy Living (NFHL) study (2000-2003) and prevalence relative to the findings of the National Health and Nutrition Examination Survey (NHANES) (1999-2002). (natap.org)
Among our cohort of HIV-infected adults, the risk of developing metabolic syndrome was higher in those with a clinically relevant increase in viral load (≥0.5 log) in the previous 6 months. (natap.org)
GHD in adults is recognized as a distinct clinical syndrome that encompasses reduced psychological well-being and specific metabolic abnormalities. (medscape.com)
Adults who incorporate a healthy diet and workout regimen right from the start are more likely to experience long, fulfilling lives free from metabolic syndrome. (naturalwellbeing.com)
Prevalence of obesity and severe obesity among adults: United States, 2017-2018. (msdmanuals.com)
The metabolic syndrome classification is of interest in epidemiologic studies because of its ability to predict the development of cardiovascular disease (CVD) and type 2 diabetes in adults ( 2 ). (cdc.gov)

The western dietary pattern, obese-related anthropometric parameters, and most components of metabolic syndrome are positively associated with CRP levels and NLR in men and women with metabolic syndrome. (biomedcentral.com)

There was no association between metabolic syndrome and indinavir, nelfinavir, or nevirapine in our study. (natap.org)

Obesity (Silver Spring) , 2020 11;28(11):2035. (afpm.org.my)

Polycystic ovary syndrome is a clinical syndrome typically characterized by anovulation or oligo-ovulation, signs of androgen excess (eg, hirsutism, acne), and multiple ovarian cysts in the ovaries. (merckmanuals.com)
Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. (merckmanuals.com)

The earliest morphologic abnormality in diabetic nephropathy is the thickening of the GBM and expansion of the mesangium due to accumulation of extracellular matrix. (medscape.com)
Type 2 diabetic patients ( n = 700) were selected from a cross-sectional study that is regularly being conducted in the School of Studies in Biochemistry, Jiwaji University Gwalior, India. (ophrp.org)

0.91) had a higher incidence of metabolic syndrome/diabetes than those in the low quotient group (25 vs. 8% p = 0.04). (frontiersin.org)
The incidence of metabolic syndrome in the NFHL study was higher with increasing viral load, higher BMI, higher trunk-to-limb fat ratio, and Kaletra (lopinavir/ritonavir) or didanosine (ddI) use and lower among college-educated persons. (natap.org)
Hence, this study aims to recognize various risk factors including metabolic components and blood parameters to predict the possible incidence of the disease. (biomedcentral.com)
As a result of rapid economic, social, and cultural changes, the prevalence of obesity in Afghanistan is increasing and dietary habits are shifting from the traditional pattern to a pattern more typical of industrialized countries, with concomitant increases in the incidence of noncommunicable diseases (NCDs). (who.int)

Unhealthy diets leading to an excessive calorie intake coupled with sedentary lifestyles are the most common causes of obesity and excess weight. (kauveryhospital.com)
Obesity Obesity is excess body weight, defined as a body mass index (BMI) of ≥ 30 kg/m 2 . (merckmanuals.com)
Metabolic syndrome occurs when the body can't properly metabolize the excess amounts of sugar and fat present in unbalanced diets. (naturalwellbeing.com)

Obesity is a multifactorial, highly complex medical condition involving abnormal or excessive body fat accumulation that can cause health impairment. (molvis.org)

Ultimately, BMI results are no longer sufficient to make an accurate diagnosis of obesity. (gurze.com)
Metabolic syndrome was evaluated according to the I Brazilian Guideline for the Diagnosis and Treatment of Metabolic Syndrome. (bvsalud.org)
The tricky part about metabolic syndrome is that patients can't conduct a self-diagnosis. (naturalwellbeing.com)

RÉSUMÉ La présente étude a évalué la prévalence du syndrome métabolique et ses composantes selon les critères de l' Adult Treatment Panel III chez des patients jordaniens consultant dans un établissement de soins en médecine familiale pour la prise en charge des facteurs de risque cardio-vasculaires. (who.int)

In this study we assessed the preva- having a first degree relative (parent, prevalence in various populations was lence of the metabolic syndrome and sibling or child) that has history of myo- hindered by lack of a uniform definition its individual components as defined cardial infarction or ischaemic stroke of the syndrome [1]. (who.int)
Since the 80s, studies have shown a higher prevalence of obesity among the various populations in developed and developing countries 4 . (bvsalud.org)

ing of metabolic abnormalities which hospital in the capital city of Jordan, Am- Data collection includes hyperlipidaemia [elevated tri- man), and is the primary teaching clinic glycerides (TG), low serum high-den- for the family medicine programme. (who.int)

Metabolic syndrome is mostly diagnosed through low HDL and high triglycerides in HIV. (natap.org)

Studies showed that 65% of the world's population live in countries where overweight and obesity kills more people than underweight (World Health Organization, 2012). (directcurrentmusic.com)

O verall trend data clearly indicate that obesity prevalence in U.S. children and youth has risen to distressing proportions, but many questions remain about the nature, extent, and consequences of this problem. (nationalacademies.org)
Johnathan D. Tune et al Cardiovascular Consequences of Metabolic Syndrome Transl Res. (kauveryhospital.com)
These somatic consequences could partly be due to metabolic, immuno-inflammatory, autonomic and hypothalamic-pituitary-adrenal (HPA)-axis dysregulations which have been suggested to be more often present among depressed patients. (biomedcentral.com)

The risk of having metabolic syndrome increases with age, affecting less than 10% of people in their 20's and 40% of people in their 60's. (itmedicalteam.pl)
Background: Metabolic syndrome increases the risk of cardiovascular outcomes and type II diabetes. (natap.org)

Although some behavioral and pharmacotherapy studies report modest success, additional research into accessible and effective methods for preventing and treating pediatric obesity is needed. (medscape.com)
Furthermore, continued investigation into the most effective methods of preventing and treating obesity and into methods for changing environmental and economic factors that will lead to worldwide cultural changes in diet and activity should be priorities. (medscape.com)

Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. (wikipedia.org)

Metabolic syndrome is commonly associated with inflammation. (biomedcentral.com)
The underlying factors of inflammation in metabolic syndrome are not fully understood. (biomedcentral.com)
However, the underlying factors of inflammation in metabolic syndrome are not fully understood. (biomedcentral.com)
The heterogeneity of the depression concept seems to play a differentiating role: metabolic syndrome and inflammation up-regulations appear more specific to the atypical depression subtype, whereas hypercortisolemia appears more specific for melancholic depression. (biomedcentral.com)

The mechanisms of the complex pathways of metabolic syndrome are under investigation. (wikipedia.org)
The specific mechanisms by which GCs modulate these processes remain largely unknown, but GCs increase production of endocannabinoids-potent central and peripheral regulators of appetite, energy balance, and metabolism. (iasvn.org)

Recent evidence shows that glucocorticoids possess the ability to increase endocannabinoid signaling, which is known to regulate appetite, energy balance, and metabolic processes through both central and peripheral pathways. (iasvn.org)

In obesity, the myocardium abnormally utilises fatty acids and shows an impaired ability to shift away from this increased fatty acid utilization. (kauveryhospital.com)

Multivariate logistic regression was performed to evaluate the association of dietary patterns, anthropometric measurements, and metabolic parameters with C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) in men and women with metabolic syndrome. (biomedcentral.com)
The application of WHtR provides an alternative anthropometric index of central obesity that avoids the limitations of WC because the inclusion of height into the index enhances the avoidance of any potential confounding of cardiometabolic risk by height [ 19 ]. (hindawi.com)
In the short-term anthropometric measurements and their variation overtime were not correlated with metabolic syndrome/diabetes. (frontiersin.org)
Both anthropometric measures were useful screening tools to identify metabolic syndrome. (cdc.gov)

Depression has been shown to subsequently increase the risk of, for example, cardiovascular, stroke, diabetes and obesity morbidity. (biomedcentral.com)

Anatomy12

Organisms6

Diseases84

Chemicals and Drugs36

Analytical, Diagnostic and Therapeutic Techniques and Equipment58

Psychiatry and Psychology10

Phenomena and Processes53

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture6

Information Science4

Named Groups6

Health Care41

Geographicals12

Hypertension24

High-density lip6

Insulin37

MetS19

Abdominal12

Prevalence of metabolic syndrome6

Circumference10

Glucose7

Signs of metabolic syndrome2

Development of metabolic syndrome2

Hypertriglyceridemia2

Cluster1

Waist2

Dysfunction3

Complications7

Lipid abnormality1

Systemic1

Significantly4

Cholesterol6

Abstract2

Phenotype2

Chronic8

Disorders7

Reproductive abnormalities1

T2DM11

Adipose tissue2

Hormonal2

Hepatic1

Definition of the metabolic syndrome1

Genetic7

Adolescents9

Criteria for metabolic syndrome1

Adults9

Components of metabolic syndrome1

Association between metabolic syndrome1

20201

Polycystic2

Diabetic2

Incidence4

Excess3

Multifactorial1

Diagnosis3

Adult Treatment Panel III1

Various populations2

Serum1

Triglycerides1

Overweight and obesity1

Consequences3

Increases2

Methods2

Risk of developing cardiovascu1

Inflammation4

Mechanisms2

Pathways1

Fatty1

Anthropometric4

Diabetes and obesity1