• The case of a middle cerebral artery aneurysm is used to illustrate the application of this methodology to the assessment of the relationship between local wall shear stress and local wall properties including collagen fiber organization and wall geometry. (montclair.edu)
  • The cerebral capillary closing pressure was determined from transcranial Doppler measurements of the arterial blood flow of the middle cerebral artery and the arterial pressure curve. (biomedcentral.com)
  • Finally, patients with mild-to-moderate HF had reduced blood flow velocity of the middle cerebral artery, compared to healthy controls (47.3 versus 56.1 cm/s, respectively) [ 6 ] . (encyclopedia.pub)
  • OBJECTIVES: To examine associations between maternal pregnancy-specific stress and umbilical (UA PI) and middle cerebral artery pulsatility indices (MCA PI), cerebroplacental ratio, absent end diastolic flow (AEDF), birthweight, prematurity, neonatal intensive care unit admission and adverse obstetric outcomes in women with small for gestational age pregnancies. (ox.ac.uk)
  • A multiple logistic regression analysis indicated that short fetal NBL (odds ratio = 0.691, 95% confidence interval: 0.551 to 0.868) and the pulsatility index (PI) of the umbilical artery (odds ratio = 8.095, 95% confidence interval: 4.309 to 15.207) and of the middle cerebral artery (odds ratio = 0.254, 95% confidence interval: 0.120 to 0.538) are significantly associated with isolated VSDs. (biomedcentral.com)
  • Late-second-trimester fetal NBL, umbilical artery PI, and middle cerebral artery PI are useful parameters for detecting isolated VSDs, and can be used to estimate the a priori risk of VSDs in women at high risk and at low risk of isolated VSDs. (biomedcentral.com)
  • In contrast to other experimental and clinical data, we observed no pathological findings in the investigated parameters of cerebral perfusion and oxygenation. (biomedcentral.com)
  • We therefore tried to investigate simultaneously various parameters to obtain a more broad survey of cerebral perfusion and oxygenation in patients with sepsis syndrome showing abnormal EEG patterns. (biomedcentral.com)
  • CREST-H addresses the intriguing question of whether cognitive impairment can be reversed when it arises from abnormal cerebral hemodynamic perfusion in a hemodynamically impaired subset of the CREST-2 -randomized patients. (researcherprofiles.org)
  • Patients with abnormal TCD received treatment to increase cerebral perfusion pressure and/or decrease cerebral edema. (rimed.com)
  • Cerebral invasive monitoring was available at ~4 hours after admission and showed similar cerebral perfusion pressure and jugular venous oxygen saturation between the two groups despite increased intracranial pressure in patients with abnormal TCD. (rimed.com)
  • In summary, the current hypothesis for the pathogenesis of preeclampsia is that an immunologic disturbance causes abnormal placental implantation resulting in decreased placental perfusion. (health.am)
  • The abnormal perfusion stimulates the production of substances in the blood that activate or injure endothelial cells. (health.am)
  • We discussed NAS, which has been rebranded as NOWS, and its effect on cerebral perfusion on brain MRI. (the-incubator.org)
  • Cerebral perfusion and neurological examination characterise neonatal opioid withdrawal syndrome: a prospective cohort study. (the-incubator.org)
  • CDMS is strongly associated with CCSVI, a scenario that has not previously been described, characterised by abnormal venous haemodynamics determined by extracranial multiple venous strictures of unknown origin. (bmj.com)
  • Most hemodynamic and geometric features in a commonly used elastase-induced rabbit saccular aneurysm model are qualitatively and quantitatively similar to those seen in large numbers of human cerebral aneurysms. (ajnr.org)
  • Previous investigators have postulated that the manner in which the walls of IAs remodel under the abnormal intrasaccular hemodynamic stresses plays a major role in the stabilization or eventual rupture of the aneurysm. (ajnr.org)
  • 1 - 6 As a result, a large body of research has been directed at categorizing the hemodynamics inside human IAs and correlating aneurysm growth as well as rupture with specific hemodynamic markers such as abnormally high or low magnitudes of WSS and OSI. (ajnr.org)
  • Here, we report a case of hikikomori for which an exercise intervention using jogging therapy was effective, showing cerebral hemodynamic improvement. (clinical-practice-and-epidemiology-in-mental-health.com)
  • Using near infrared spectroscopy to evaluate hemodynamic alteration, bilateral temporal hemodynamics considerably increased after the three-month jogging therapy. (clinical-practice-and-epidemiology-in-mental-health.com)
  • We aim to determine whether cognitive impairment attributable to cerebral hemodynamic impairment in patients with high-grade asymptomatic carotid artery stenosis is reversible with restoration of flow. (researcherprofiles.org)
  • Cerebral vascular injury and hemodynamic compromise is a significant contributor to poor outcome in patients with TBI. (rimed.com)
  • Hemodynamics and Anatomy of Elastase-Induced Rabbit Aneurysm Models: Similarity to Human Cerebral Aneurysms? (ajnr.org)
  • Animal models provide a mechanism for fundamental studies of the coupling between hemodynamics and pathophysiology in diseases such as saccular aneurysms. (ajnr.org)
  • The evolution of intracranial aneurysms (IAs) is thought to be driven by progressive wall degradation in response to abnormal hemodynamics. (montclair.edu)
  • However, hemodynamics, wall structure and mechanical properties of cerebral aneurysms can be non-uniform across the aneurysm wall. (montclair.edu)
  • 02 11 2010 18 11 2011 21 12 2011 21 12 2011 blood vessels computational fluid dynamics haemodynamics medical computing pipe flow computational fluid dynamics blood flow numerical simulation. (asme.org)
  • This methodology combines image-based computational fluid dynamics, tissue resection, micro-CT imaging of resected specimens mounted on 3D-printed aneurysm models, alignment to 3D vascular models, multi-photon microscopy of the wall, and regional mapping of hemodynamics and wall properties. (montclair.edu)
  • 1 2 MR venography 3 - 6 and postmortem studies 7 have demonstrated a topographic correspondence between MS plaques and cerebral venous system. (bmj.com)
  • Magnetic resonance venography[4-7] and post mortem studies [8] demonstrated a topographic correspondence between multiple sclerosis plaques and the cerebral venous system. (ccsvi.nl)
  • After approval of the institutional ethics committee, 10 mechanically ventilated patients with sepsis syndrome and pathological electroencephalogram patterns underwent measurements of cerebral blood flow and jugular venous oxygen saturation before and after reduction of the arterial carbon dioxide partial pressure by 0.93 ± 0.7 kPa iu by ypervent ilation. (biomedcentral.com)
  • The primary outcomes will include interventions used to maintain cerebral saturation in target range, rates of cerebral hypoxia and systemic hypoxia, and a composite of death or severe brain injury detected on term-equivalent magnetic resonance imaging. (stanford.edu)
  • Whether alterations of systemic or cerebral circulation might play a role in sepsis-induced encephalopathy, however, has not yet been determined. (biomedcentral.com)
  • Treatment is improvement of systemic hemodynamics. (msdmanuals.com)
  • The Brain Oxygenation-II study (BOx-II) is a phase-II, multicenter, single-arm clinical trial evaluating interventions based on near-infrared spectroscopy (NIRS) monitoring of cerebral oxygen saturation in extremely premature infants. (stanford.edu)
  • Enrolled infants will follow a treatment guideline to maintain cerebral oxygen saturation in a target range within the first 72 hours of life. (stanford.edu)
  • Disturbances in cerebral hemodynamics with an early phase of cerebral hypoperfusion followed by hyperemia and secondary elevations in ICP may be one possible mechanism. (rimed.com)
  • PRIMARY AND SECONDARY OUTCOME MEASURES: Serial Doppler ultrasound examinations of the umbilical and middle cerebral arteries between 20 and 42 weeks gestation, Pregnancy Distress Questionnaire (PDQ) scores between 23 and 40 weeks gestation and neonatal outcomes. (ox.ac.uk)
  • All of these elements convinced the current authors to investigate Doppler cerebral venous hemodynamics. (ccsvi.nl)
  • The pathophysiological significance of changes in CSF volume is assessed from the respective viewpoints of hemodynamics (choroid plexus blood flow and pulsatility), hydrodynamics (choroidal hypo- and hypersecretion) and neuroendocrine factors (i.e., coordinated regulation by atrial natriuretic peptide, arginine vasopressin and basic fibroblast growth factor). (scienceopen.com)
  • The critically attained threshold of cerebral hypoperfusion ('CATCH') theory supports the fact that aging in conjunction with vascular risk factors leads to chronic cerebral hypoperfusion and increased risk of Alzheimer's disease (AD) [ 1 ] . (encyclopedia.pub)
  • However, the reasons of brain hypoperfusion in HF include not only the low cardiac output, due to HF, but also the compromised cerebral autoregulation [ 1 ] . (encyclopedia.pub)
  • These findings show that early TCD monitoring can help prevent cerebral hypoperfusion, which may help reduce the extent of secondary ischemic injuries in TBI patients with elevated ICP. (rimed.com)
  • We hypothesized that cerebral haemodynamics and carbon dioxide reactivity would be impaired in patients with sepsis syndrome and pathological electroencephalogram patterns. (biomedcentral.com)
  • Additionally, cerebrovascular reactivity, measured by the response of cerebral vasculature to high levels of carbon dioxide, becomes abnormal. (encyclopedia.pub)
  • Increasing attention focuses on CSF flow: how it impacts cerebral metabolism and hemodynamics, neural stem cell progression in the subventricular zone, and catabolite/peptide clearance from the CNS. (scienceopen.com)
  • We present the results of a study that evaluated the abnormalities of the cerebral venous outflow in patients with MS using ECD-TCCS and selective venography. (bmj.com)
  • To investigate the feasibility and usefulness of 2-deoxy-2-( 18 F)-fluoro-D-glucose positron emission tomography/computed tomography [( 18 F)-FDG PET/CT] as a novel examination in the surveillance of abnormal myocardial energy metabolism and cardiac dysfunction after cardiopulmonary resuscitation (CPR). (dirjournal.org)
  • Pregnancy-specific stress, fetoplacental haemodynamics, and neonatal outcomes in women with small for gestational age pregnancies: a secondary analysis of the multicentre Prospective Observational Trial to Optimise Paediatric Health in Intrauterine Growth Restriction. (ox.ac.uk)
  • It was hypothesised that maternal pregnancy-specific stress would be associated with fetoplacental haemodynamics and neonatal outcomes. (ox.ac.uk)
  • CONCLUSIONS: These findings suggest that fetoplacental haemodynamics may be a mechanistic link between maternal prenatal stress and fetal and neonatal well-being, but additional research is required. (ox.ac.uk)
  • Atherosclerosis, a vascular disease characterized by abnormal deposits upon vessel walls or thickening thereof, is an example of an abnormal wall condition. (justia.com)
  • Previous studies have found that vascular inflammation promotes plaque formation, and inflamed fat tissue has abnormal secretion of cell signaling molecules, which predispose people to cognitive decline. (news-medical.net)
  • haemodynamics prosthetics shear flow Cardiac valve prosthesis Transvalvular flow Strains Blood damaging potential Heart valves that fail to perform their physiological function correctly can be replaced either by mechanical or biological prosthetic valves. (asme.org)
  • Prediction of Communication Impairment in Children With Bilateral Cerebral Palsy Using Multivariate Lesion- and Connectome-Based Approaches: Protocol for a Multicenter Prospective Cohort Study. (cdc.gov)
  • Sodium nitroprusside should be reserved for extreme emergencies and used for the shortest amount of time possible because of concerns about cyanide and thiocyanate toxicity in the mother and fetus or newborn, and increased intracranial pressure with potential worsening of cerebral edema in the mother. (medscape.com)
  • Many abnormal medical conditions in humans and other mammals have been associated with disease and other aberrations along the lining or walls which define several different body spaces. (justia.com)
  • Furthermore, alterations in cardiac hemodynamics, irrespective of cardiovascular risk factors and co-morbidities, are linked to reduced brain function. (encyclopedia.pub)
  • To decide whether an induced blood flow alteration is sufficient for aneurysm occlusion is an essential task that the treating doctor currently fulfills by visually comparing cerebral angiography sequences taken before and after flow diverter placement. (tum.de)
  • Cerebral blood flow (CBF) reduction is further compounded by the negative action of other co-morbidities, such as hypertension, diabetes, sleep apnea and depression [ 2 ] . (encyclopedia.pub)
  • Mechanism is thought to be change in cerebral blood flow and pH. (msdmanuals.com)
  • This review aims to provide updated information on the role of abnormal sleep in the development of stroke, to discuss the implications of recent research findings, and to help both stroke clinicians and researchers understand the importance of identification and management of sleep pathology for stroke prevention and care. (j-stroke.org)
  • In contrast, MR and selective injection venography are of course limited in evaluating cerebral venous haemodynamics under different postural and respiratory conditions. (bmj.com)
  • Diagnosis of suspicious abnormal extraeranial cerebral venous outfiow must fulfil at least two of the five criteria listed in Table 1 and is taken as an indication approved by the Ethical Committee of the current authors' hospital to continue the study using selective venography in all suspccted subjects. (ccsvi.nl)
  • 02 05 2011 17 11 2011 23 12 2011 23 12 2011 biomechanics cardiology diseases elongation haemodynamics numerical analysis physiological models vortices An abdominal aortic aneurysm (AAA) is a dilation of at least 1.5 times the diameter of the largest. (asme.org)
  • In order to treat such abnormal wall conditions of the body spaces, medical device technologies adapted for delivering specific forms of ablative energy to specific regions of targeted wall tissue from within the associated body space have been developed and disclosed. (justia.com)
  • In the periphery, degenerating tissue and the deposition of highly insoluble abnormal materials are classical stimulants of inflammation. (scienceopen.com)
  • It is commonly accepted that hemodynamics play a role in the initiation and further development of arterial pathologies such as IAs. (ajnr.org)
  • Most patients with sepsis develop potentially irreversible cerebral dysfunctions. (biomedcentral.com)
  • It is yet not clear whether cerebral haemodynamics are altered in these sepsis patients at all, and to what extent. (biomedcentral.com)
  • Compte tenu du nombre croissant d'infections et de décès par le virus de la grippe pandémique (H1N1) 2009 confirmés en laboratoire dans la Région OMS de la Méditerranée orientale, le Bureau régional a convoqué une réunion consultative d'experts impliqués dans la prise en charge clinique de patients infectés par ce virus. (who.int)
  • This local change in hemodynamics supposedly leads to flow stasis and thrombus formation inside the aneursym, eventually cutting it off from the normal circulation of blood. (tum.de)
  • In most of the former studies concerning cerebral haemodynamics during sepsis syndrome, only a few aspects of cerebral circulation had been investigated. (biomedcentral.com)
  • RESULTS: Concerns about physical symptoms and body image at 35-40 weeks were associated with lower odds of abnormal UAPI (OR 0.826, 95% CI 0.696 to 0.979, p=0.028). (ox.ac.uk)
  • PDQ score (OR 1.073, 95% CI 1.012 to 1.137, p=0.017), concerns about birth and the baby (OR 1.143, 95% CI 1.037 to 1.260, p=0.007) and concerns about physical symptoms and body image (OR 1.283, 95% CI 1.070 to 1.538, p=0.007) at 29-34 weeks were associated with higher odds of abnormal MCA PI. (ox.ac.uk)
  • Altered hemodynamics in neonates, especially in relation to prematurity, congenital heart disease, and central nervous system injury. (stanford.edu)
  • fMRI is used to measure the changes in hemodynamics caused by neuronal activity which can show the location and extent of brain activation and can detect dynamic changes in the brain over a period of time. (hindawi.com)
  • 18 F)-fluoro-D-glucose positron emission tomography/computed tomography can be used to evaluate myocardial damage after CPR by monitoring abnormal glucose metabolism. (dirjournal.org)
  • Does this patient have abnormal central venous pressure? (mcmaster.ca)
  • Therefore, the aim of this work is to introduce a methodology for mapping local hemodynamics to local wall structure in resected aneurysm specimens. (montclair.edu)
  • Research has consistently shown significant prefrontal activation during tasks in typically developed children, but this activation may be abnormal in children with developmental disorders. (frontiersin.org)
  • A cerebral aneurysm is an abnormal dilation of a blood vessel in the brain that harbours the risk of rupturing. (tum.de)
  • Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRß, a marker of blood brain barrier breakdown, in older adults Res Sq. 2023 Mar 07. (usc.edu)
  • Post-resuscitation myocardial injury is evidently due to oxidative stress, calcium overload, neutrophil accumulation, microvascular damage, and abnormal energy metabolism, among other causes. (dirjournal.org)
  • Abnormal and uncontrolled activation of these enzymes leads to cellular damage after CPB. (medscape.com)
  • Management of CHD emphasizes early complete repair before the heart and the patient deleteriously adapt to the abnormal physiology. (medscape.com)