• A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. (wikipedia.org)
  • Biofilms can attach to a surface such as a tooth or rock, and may include a single species or a diverse group of microorganisms. (wikipedia.org)
  • The formation of a biofilm begins with the attachment of free-floating microorganisms to a surface. (wikipedia.org)
  • Disinfection methods currently used in water systems have been shown to be ineffective against legionella over the long-term, allowing recolonization by the biofilm-protected microorganisms. (frontiersin.org)
  • Microorganisms have the extraordinary ability to live in almost all environments and to protect themselves from external agents through sophisticated survival mechanisms. (intechopen.com)
  • In this thesis, the interplay between the current produced at anodes and the growth of these microorganisms was studied, as well as their ability to store electrons. (sense.nl)
  • The ability of microorganisms to attach to diverse surfaces and form complex colonies known as biofilms vastly improves their survival and growth in environmental niches. (waterandhealth.org)
  • Biofilms form when bacteria adhere to surfaces by excreting a slimy, glue-like substance, and can include algae, protozoa, and other microorganisms. (waterandhealth.org)
  • The microorganisms in biofilms composed of 50-500 times increase their resistance to disinfectants, antimicrobials, bacteriophages, phagocytes and antibodies. (scholarsresearchlibrary.com)
  • Consequently, we can assume that the adhesive properties and increase the level of teichoic acids from clinical isolates of S. aureus is a sign of pathogenicity and virulence, which may affect the ability of microorganisms to biofilm formation. (scholarsresearchlibrary.com)
  • This biofilm, consisting of bacteria and other microorganisms, allows the Lyme spirochete to hide and resist harsh environmental conditions such as antibiotic treatments. (holtorfmed.com)
  • The development of hospital-acquired pneumonia (HAP) represents an imbalance between normal host defenses and the ability of microorganisms to colonize and then invade the lower respiratory tract. (medscape.com)
  • [8] [5] The first colonist bacteria of a biofilm may adhere to the surface initially by the weak van der Waals forces and hydrophobic effects. (wikipedia.org)
  • Jan. 31, 2022 Most bacteria have the ability to form communities, biofilms, that adhere to a wide variety of surfaces and are difficult to remove. (sciencedaily.com)
  • The ability of Streptococcus mutans to adhere to oral surfaces and form biofilm is a key step in the tooth decay process. (cranberryinstitute.org)
  • The ability of Elizabethkingia meningoseptica isolate CH2B from freshwater tilapia ( Oreochromis mossambicus ) and E. meningoseptica strain NCTC 10016 T to adhere to abiotic surfaces was investigated using microtiter plate adherence assays following exposure to varying physico-chemical challenges. (biomedcentral.com)
  • The ability of E. meningoseptica isolates to adhere to abiotic surfaces and form biofilm structures may result from the hydrophilic cell surface and multiple adhesins located around the cell. (biomedcentral.com)
  • The locus of the psl polysacchide genes encode the cells to adhere to a surface and thus maintaining the biofilm structure. (ukessays.com)
  • EAEC bacterial cells form biofilms that adhere to the intestinal mucosa and elaborate enterotoxins and cytotoxins causing diarrhoea and mucosal damage. (i-sis.org.uk)
  • The ability of P acnes to adhere to and form a biofilm, particularly on prosthetics, for example, is characteristic of the infections that it may cause. (medscape.com)
  • Historically, multicellular bacterial communities, known as biofilms, have been thought to be held together solely by a self-produced extracellular matrix. (nature.com)
  • A major virulence factor of Candida is its ability to adapt to a variety of different habitats and the consequent formation of surface-attached microbial communities known as biofilms [ 5 ]. (biomedcentral.com)
  • However, all Candida species produced a similar biofilm on acrylic resin, material used in dental prostheses. (biomedcentral.com)
  • We found that on silicone pads as well as in the Galleria model, biofilm formation and virulence depends on the Candida species. (biomedcentral.com)
  • Importantly, for C. albicans the pathogenicity of oral Candida isolates was similar to systemic Candida isolates, suggesting that Candida isolates have similar biofilm-forming ability and virulence regardless of the infection site from which it was isolated. (biomedcentral.com)
  • The virulence factors of Candida albicans are germ tube and biofilm formation, adherence to host tissues, and production of hydrolytic enzymes. (hindawi.com)
  • In vitro biofilm formation and relationship with antifungal resistance of Candida spp. (who.int)
  • The aims of this study were (i) to detect the biofilm production characteristics of Candida spp. (who.int)
  • Biofilm formation rate of vaginal C.albicans isolates was significantly lower than vaginal non-albicans Candida spp. (who.int)
  • Fluconazole resistance was significantly higher in biofilm-producing vaginal Candida spp. (who.int)
  • Resistance rates for both fluconazole and itraconazole were higher in biofilm-producers (39.5% and 52.6%, respectively), than those of non-producers (10.6% and 29.8%, respectively), representing a statistical significance (p= 0.002 and p= 0.03, respectively) for Candida spp. (who.int)
  • We have shown that the biofilm formation in C. albicans and other Candida species can be significantly reduced by the addition of glucono-δ-lactone (GDL). (lu.se)
  • But, when normal probiotic defenses break down and conditions are ripe for Candida to overgrow, it changes its form and goes into attack mode, wreaking havoc in your body and causing a whole host of symptoms and problems. (tasteforlife.com)
  • The changing face and form of Candida is what makes it such a challenge to effectively treat and reduce back to peaceable levels. (tasteforlife.com)
  • More than 20 strains of Candida have been identified in the human body, and this fungus takes on several different forms in order to protect itself from being eradicated. (tasteforlife.com)
  • This protective biofilm allows Candida to create an environment it thrives in, with just the right pH and plenty of food to keep doing its dastardly deeds and growing its population. (tasteforlife.com)
  • We compared oral and systemic isolates for the capacity to form biofilm in an in vitro biofilm model and pathogenicity in the Galleria mellonella infection model. (biomedcentral.com)
  • The biofilm formation and pathogenicity in Galleria was similar between oral and systemic isolates. (biomedcentral.com)
  • In addition, 10 clinical NTHi isolates from patients with CF formed biofilms on plastic surfaces. (nih.gov)
  • In the present study the ability of clinical isolates of Salmonella enterica serovars Typhi (n = 30) and Paratyphi A (n = 11) to form biofilm on abiotic surface was investigated. (banglajol.info)
  • All isolates were found capable of biofilm formation in a microtitre plate assay. (banglajol.info)
  • Upon optimization of biofilm formation by the test isolates, Adherence test medium (ATM) was found to be the best medium for biofilm formation by both S. enterica serovars Typhi and Paratyphi. (banglajol.info)
  • Of the 28 Salmonella Typhi isolates, 17 (61%) were very strong biofilm producers, 8 (29%) were strong biofilm producers and 3 (11%) were moderate biofilm producers. (banglajol.info)
  • The present study raises concern from a public health point of view because the ability of the clinical isolates to form biofilm would indicate their ability of being transmitted from abiotic surface to uninfected host giving rise to disease. (banglajol.info)
  • Biofilm formation was evaluated by crystal violet staining and XTT-reduction assays, and the isolates which yielded positive results in both of the methods were accepted as biofilm-producers. (who.int)
  • The total in vitro biofilm formation rate was 25% (21/83) for vaginal isolates and 44.7% (38/85) for IUD string isolates. (who.int)
  • E. meningoseptica isolates CH2B and NCTC 10016 T demonstrated stronger biofilm formation in nutrient-rich medium compared to nutrient-poor medium at both 21 and 37°C, respectively. (biomedcentral.com)
  • Additionally, the biofilm inhibitory concentration values of neofiscalin A against the MRSA and VRE isolates were 96 and 80 μg mL(-1), respectively. (nih.gov)
  • Isolates were tested for antibiotic susceptibility as well as their ability to tolerate chlorine at a concentration of 0.5 mg/L. (who.int)
  • S. aureus produces large biofilm formations that support its pathogenicity and confer protection and subsequently drug resistance ( 5 ). (frontiersin.org)
  • E. meningoseptica isolate CH2B and strain NCTC 10016 T displayed a strong biofilm-forming phenotype which may play a role in its potential pathogenicity in both clinical and aquaculture environments. (biomedcentral.com)
  • In summary, the GAS surface adhesin Scl1 may have an important role in biofilm-associated pathogenicity. (cdc.gov)
  • The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)
  • The microbial community is also a natural source of metabolites and has the potential to be used to create antimicrobial and anti-biofilm agents. (frontiersin.org)
  • Bacteria growing in biofilms are less sensitive to antimicrobial resistance treatment and are more likely to secrete toxins and express disease-causing molecules. (foodnavigator.com)
  • The researchers' findings indicate that spider silk proteins functionalized with antimicrobial peptides can be used to create an effective coating for commercial silk sutures to reduce, prevent, or eliminate bacterial adhesion and biofilm formation, which lead to infection. (materialstoday.com)
  • The concentration of the chemicals tested as anti-biofilm agents was chosen based on cytotoxicity assays: the highest non-cytotoxic chemical concentration was used for biofilm inhibition assays, with dendrimer concentration 10-fold higher than polyamino-phenolic ligands. (frontiersin.org)
  • [2] [3] The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides , proteins , lipids and DNA . (wikipedia.org)
  • Using a soil bacterium called Bacillus subtilis , Dr Stanley-Wall has investigated the genes and proteins required for biofilms to develop. (sciencedaily.com)
  • Biofilm is a complex matrix consisting of extracellular polysaccharides, DNA, and proteins that protect bacteria from a variety of physical, chemical, and biological stresses allowing them to survive in hostile environments. (intechopen.com)
  • In this section, we will focus on proteins involved in biofilm formation as useful targets for the development of new drugs that can effectively and specifically impair biofilm formation with slight effects on cell survival, thus avoiding the generation of drug-resistant strains. (intechopen.com)
  • The biofilm matrix consists of polysaccharides, proteins, and DNA and constitutes a stubborn source that protects bacteria from a variety of physical, chemical, and biological stresses. (intechopen.com)
  • The differentially expressed genes and proteins linked to S. aureus biofilms have been identified using transcriptomic and proteomic investigations ( 14 - 17 ). (frontiersin.org)
  • When the intracellular concentration of autoinducers is low, autoinducer receptors act as kinases , transferring phosphate to LuxO (LuxO~P). LuxO~P promotes the expression of proteins used for building biofilms. (asm.org)
  • The key arguments for carbon-based life are the ubiquity of organic (carbon-containing) compounds in the universe and the ability of carbon to form stable compounds with many elements, thus creating the wide variety of structural, catalytic, and informational macromolecules (very large molecules, such as DNA and proteins) that make up Earth life. (nationalacademies.org)
  • Once the Borrelia burgdorferi bacterium is in the body, it starts to change its form by altering the proteins on its outer cell wall, effectively hiding itself from the immune system. (holtorfmed.com)
  • But with the ability to change its outer-cell-wall proteins, the Lyme bacteria becomes hidden from the immune system, almost like an invader who suddenly dons a disguise. (holtorfmed.com)
  • genetically modified RbmA to only form dimers, the proteins concentrated in the center of the matrix instead of building a stable mesh across it. (elifesciences.org)
  • These genomes reveal diverse mobile elements, including an integrative viral genome that bidirectionally replicates in a circular form and aloposons, transposons that encode the 5,000 amino acid-sized proteins Otus and Ephialtes. (darkenergybiosphere.org)
  • Moreover, neofiscalin A, when present at sub-MICs, hampered the ability of both MRSA and VRE strains to form a biofilm. (nih.gov)
  • Bravo and colleagues [ 1 ] investigated the ability of Acinetobacter pittii strains to form biofilms after long-term desiccation if they were fed with nutrient media. (medscape.com)
  • C. albicans cells bearing germ tubes are more adherent to buccal epithelial cells (BEC) than yeast forms of C. albicans [ 5 ] due to the antigens found on germ tubes [ 6 ]. (hindawi.com)
  • These biofilms exhibited decreased susceptibility to antibiotics and were adherent to epithelial surfaces. (nih.gov)
  • NTHi formed adherent biofilms on the apical surface airway epithelia with decreased susceptibility to antibiotics, and respiratory cells exhibited inflammatory and host defense responses-evidence of a dynamic host-pathogen interaction. (nih.gov)
  • The present authors hypothesised that bronchoscopy with protected specimen brush may sample biofilm-forming bacteria adherent to the airway wall, whereas traditional sputum collection may not. (ersjournals.com)
  • Recent evidence suggests that P. aeruginosa may actually grow as dense communities of exopolysaccharide-encapsulated biofilms adherent to CF patients' airways 2 - 4 . (ersjournals.com)
  • A biofilm usually begins to form when a free-swimming bacterium attaches to a surface. (wikipedia.org)
  • Legionnaires' disease is a potentially fatal pneumonia caused by Legionella pneumophila , an aquatic bacterium often found within the biofilm niche. (frontiersin.org)
  • The bacterium spreads rapidly through contaminated water sources and intestinal infections - a cycle that is promoted by the formation of biofilms. (elifesciences.org)
  • The viscoelastic properties of this biofilm contributes to its ability to evade phagocytic activities, to reduce the effectiveness of antibiotics, to develop antibiotic resistant strains, and to persist or reoccur in CF patients. (aiche.org)
  • Retrieved bacteria were genotyped, and grown in planktonic cultures and as biofilms, and susceptibilities to individual antibiotics and to antibiotic combinations were determined. (ersjournals.com)
  • Susceptibility to single antibiotics and to antibiotic combinations were not different between planktonically or biofilm-grown bacteria derived from sputum, as compared to those obtained by bronchoalveolar lavage and protected brush. (ersjournals.com)
  • Here, we used untargeted metabolomics to investigate the potential impacts of planktonic bacteria (LAB-pk-CFS) and biofilm colonies (LAB-bf-CFS) on the metabolism of S. aureus biofilms. (frontiersin.org)
  • V. cholerae builds biofilms to help transport nutrients between colonies while simultaneously protecting them. (asm.org)
  • Biofilms may form on living (biotic) or non-living (abiotic) surfaces and can be prevalent in natural, industrial, and hospital settings. (wikipedia.org)
  • Bacteria can be found in planktonic form or in specific conditions, as sessile aggregates on both biotic and abiotic surfaces originating complex structures known as biofilm. (intechopen.com)
  • Microbes form a biofilm in response to a number of different factors, [9] which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . (wikipedia.org)
  • The planktonic cells grow very rapidly whereas the bacterial adhering takes some time to form biofilm in other case. (ukessays.com)
  • Our hypothesis is that certain polyhydroxylated carboxylic acids, that may serve as an alternative carbohydrate source and at the same time lower the pH, function as an indicator of a nutrient-rich environment for C. albicans, which favors planktonic cells over hyphae, and thus diminish the formation of biofilm. (lu.se)
  • [13] The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
  • These unique abilities of the Lyme bacteria to hide from the body's immune system create a need for a multisystem, integrated treatment approach. (holtorfmed.com)
  • On silicone pads, C. albicans and C. dubliniensis produced more biofilm (1.12 to 6.61 mg) than the other species (0.25 to 3.66 mg). (biomedcentral.com)
  • angustifolia extract on the germ tube and biofilm formation of C. albicans . (hindawi.com)
  • DVA extract has ability to reduce virulence of C. albicans by inhibiting germ tube and biofilm formation through damage to the cell wall. (hindawi.com)
  • The ability to switch between yeast and hyphal morphologies can play a role in the virulence of C. albicans [ 4 ]. (hindawi.com)
  • The present study investigated the effect of subinhibitory concentration of crude extract of DVA on the germ tube and biofilm formation by C. albicans . (hindawi.com)
  • Biofilm formation rate of C.albicans strains isolated from vaginal and IUD string samples were found as 14.8% (8/54) and 45.5% (30/66), with a statistically significant importance (p 0.05]. (who.int)
  • The main virulence factor of C. albicans is the ability to transform from planktonic yeast-form cells into a filamentous form (hyphae or pseudohyphae), with the subsequent formation of biofilm. (lu.se)
  • Biofilms were grown on coverslips in the presence of plant extracts and processed for scanning electron microscopy (SEM). (hindawi.com)
  • RESULTS: Biofilm formation by M1-, M3-, M28-, and M41-type GAS strains, representing an intraspecies breadth, were analyzed spectrophotometrically following crystal violet staining, and characterized using confocal and field emission scanning electron microscopy. (cdc.gov)
  • Additionally, it inhibits the physiological traits of the S. aureus biofilm, including hydrophobicity, motility, eDNA, and PIA associated to the biofilm. (frontiersin.org)
  • Pathogenic characteristics such as germ tube and biofilm formation and production of tissue damaging enzymes are possible targets of new drugs. (hindawi.com)
  • However, there have not been many investigations on how pathogenic bacteria are affected by the metabolic properties of planktonic and biofilm probiotics. (frontiersin.org)
  • These pathogenic changes include greater formation of biofilms and increased adhesion and invasion of bacteria into human gut cells. (foodnavigator.com)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • The concentration levels of the nutrients are also compared for both biofilm and planktonic fermentation. (ukessays.com)
  • However, in spite of its toughness, the matrix must remain permeable to nutrients and flexible so that the biofilm can continue to grow. (elifesciences.org)
  • Despite the reduction in culturability over time, all strains that recovered from starvation on solid-surface experiments retained their capacity to form biofilms after rehydration, an addition of nutrients, and changing temperature. (medscape.com)
  • However, when the epithelial barrier is breached due to trauma, immunosuppression, or hormonal alterations, the budding form is converted into a hyphal form which causes invasion of submucosal tissues [ 3 ]. (hindawi.com)
  • The hyphal form, constituted by filamentous cells, has the ability to invade tissue and induce inflammation. (lu.se)
  • On the other hand, out of 13 S . Paratyphi, 9 (69%) were very strong biofilm producers, 3 (23%) were strong biofilm formers and 1 (8%) was a moderate biofilm producer. (banglajol.info)
  • Other virulence properties are adherence to host tissues and prostheses and ability to produce hydrolytic enzymes. (hindawi.com)
  • Effect of a berry polyphenolic fraction on biofilm formation, adherence properties and gene expression of Streptococcus mutans and its biocompatibility with oral epithelial cells. (cranberryinstitute.org)
  • The receptors then dephosphorylate LuxO, leading to shut down of biofilm-specific gene expression. (asm.org)
  • The results from the planktonic and biofilm gene expression results are compared. (ukessays.com)
  • Biofilm formation requires three different stages: cell attachment to a solid substrate, adhesion, and growth. (intechopen.com)
  • The aim of this study was to investigate a berry (wild blueberry, cranberry, and strawberry) polyphenolic fraction, commercialized as OrophenolR, for its antibacterial, anti-biofilm, and anti-adhesion properties on S. mutans. (cranberryinstitute.org)
  • The study found concentrations of all three artificial sweeteners equivalent to two cans of diet soft drink, could increase the adhesion of E. coli and E. faecalis to intestinal Caco-2 cells, and increase biofilm formation. (foodnavigator.com)
  • In man-made water systems microbial biofilms increase the resistance of legionella to disinfection, posing a significant threat to public health. (frontiersin.org)
  • These data suggest that the studied compounds, especially dendrimers, could be considered as novel molecules in the design of research projects aimed at the development of efficacious anti-biofilm disinfection treatments of water systems in order to minimize legionellosis outbreaks. (frontiersin.org)
  • Three recent articles [ 1 , 2 , 3 ] highlight how our understanding of bacterial persistence and recent advances in disinfection modalities may provide a means for control of biofilms and nosocomial infections. (medscape.com)
  • Biofilms are an ensemble of microbial cells irreversibly associated with a surface and enclosed in an essentially self-produced matrix. (intechopen.com)
  • Bacteria biofilms are increasingly recognized as contributing to bacterial persistence and disease pathogenesis in CF. (nih.gov)
  • Alfa and colleagues [ 2 ] looked at the impact of improper positioning of the elevator lever of a duodenoscope on bacterial persistence, biofilm formation, and endoscope contamination. (medscape.com)
  • Biofilms are multicellular communities that were so far thought to be held together solely by a self-produced organic extracellular matrix. (nature.com)
  • As single-celled organisms bacteria are exposed to a variety of stresses, but their ability to form multicellular structures called biofilms helps them to grow and survive in challenging environments. (elifesciences.org)
  • Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
  • A leading expert explains it is important to understand how biofilms form as they are often the basis of chronic infections and also of bioremediation processes. (sciencedaily.com)
  • In the 2009 Fleming lecture, given at the Society for General Microbiology's meeting in Harrogate March 30, Dr Nicola Stanley-Wall from the University of Dundee explained that it is important to understand how biofilms form as they are often the basis of chronic infections and also of bioremediation processes. (sciencedaily.com)
  • More detailed information on how bacteria develop into biofilms will allow scientists to work on alternative strategies to treat biofilm related infections and may improve technologies for waste water treatment plants or microbial fuel cells. (sciencedaily.com)
  • The capacity of S. aureus to build biofilms is correlated with the severity of infections ( 4 ). (frontiersin.org)
  • To further investigate the pathogenesis of NTHi in respiratory infections, we developed a novel in vitro coculture model of NTHi biofilm formation on polarized human airway epithelial cells grown at the air-liquid interface. (nih.gov)
  • May lead to vaginal infections by inducing biofilm formation in IUD strings and these biofilms may be related to resistance to antifungal agents. (who.int)
  • However, sutures can harbor bacteria, leading to the formation of biofilms and related infections, which can be problematic to treat. (materialstoday.com)
  • Their ability to exist as biofilm structures has been alluded to but not extensively investigated. (biomedcentral.com)
  • demonstrated that far from being inert, the matrix components are dynamic structures that interact with each other to maintain the biofilm architecture. (elifesciences.org)
  • The aim of this project is to study of species composition of biofilm communities by cultivation and molecular methods and assessment of the differences in poly-microbial communities in relation to therapy failure, length of insertion of catheter, its type and other factors including predominating microbial species. (muni.cz)
  • In this study, the anti-biofilm activity of previously fabricated polyamino-phenolic ligands and polyamidoamine dendrimers was investigated against legionella mono-species and multi-species biofilms formed by L. pneumophila in association with other bacteria that can be found in tap water ( Aeromonas hydrophila , Pseudomonas aeruginosa , Escherichia coli , Klebsiella pneumoniae ). (frontiersin.org)
  • While Macrophen and Double Macrophen were the most active substances among polyamino-phenolic ligands, dendrimers were overall twofold more effective than all other compounds with a reduction up to 85 and 73% of legionella and multi-species biofilms, respectively. (frontiersin.org)
  • The quantity of biofilm formed and the virulence in G. mellonella were different for each of the species studied. (biomedcentral.com)
  • These findings are consistent with a tendency of other Acinetobacter species to survive on dry surfaces, form biofilms, and contribute to nosocomial outbreaks. (medscape.com)
  • It can be difficult to detect the presence of V. cholerae in water sources, due to the bacterium's ability to aggregate into of conditionally viable environmental cells (CVECs) (3). (kenyon.edu)
  • V. cholerae also forms biofilms upon colonization on their copepod symbionts. (kenyon.edu)
  • The quorum sensing system V. cholerae uses to regulate biofilm formation. (asm.org)
  • V. cholerae 's insidious but abrupt biofilm formation starts immediately after it enters a person's small intestine. (asm.org)
  • Biofilm production comes to a simultaneous halt across all V. cholerae bacteria, and a new sequence of quorum sensing moves V. cholerae through its infectious process. (asm.org)
  • For instance, one exciting study demonstrated that overloading V. cholerae with its autoinducer can halt the process of biofilm formation completely, and potentially delay the infectious process enough for our immune systems to catch up. (asm.org)
  • A structural switch controls the architecture of Vibrio cholerae biofilms by mediating the interactions between two matrix components. (elifesciences.org)
  • Because the lifecycle of V. cholerae depends on switching between planktonic and biofilm states, the components of the matrix must remain dynamic. (elifesciences.org)
  • How do single celled bacteria living as part of a complex community called a biofilm "decide" between different physiological processes, such as movement or producing the "glue" that forms the biofilm? (sciencedaily.com)
  • So how do individual bacterial cells living as part of a complex community called a biofilm "decide" between different physiological processes (such as movement or producing the "glue" that forms the biofilm)? (sciencedaily.com)
  • Two issues are being addressed by the astrobiology community: our incomplete understanding of the physiological diversity of Earth life, and the near absence of data on possible alternative forms of carbon-based biochemistries. (nationalacademies.org)
  • Biofilms are thought to have arisen during primitive Earth as a defense mechanism for prokaryotes, as the conditions at that time were too harsh for their survival. (wikipedia.org)
  • Biofilm formation and bacterial viability during the survival analysis were assessed. (medscape.com)
  • Cite this: Survival of the Slimiest: The Persistent Nature of Biofilms - Medscape - Mar 22, 2018. (medscape.com)
  • The exopolysaccharide matrix is the important component of the biofilm. (ukessays.com)
  • The exopolysaccharide genes such as pilB, pslA, lecA, ureB and alginate genes are responsible for the formation of pseudomonas biofilms. (ukessays.com)
  • The disruption of biofilm formation would have a beneficial impact on the treatment of diseased CF patient as it will make the infection more susceptible to antibiotics and host phagocytosis. (aiche.org)
  • [10] [11] A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated . (wikipedia.org)
  • The berry polyphenolic preparation dose-dependently inhibited S. mutans biofilm formation while not reducing bacterial growth. (cranberryinstitute.org)
  • For each of the acquired strains, biofilm formation was evaluated on standardized samples of silicone pads and acrylic resin. (biomedcentral.com)
  • The self-produced matrix of extracellular polymeric substances , which is also referred to as slime, is a polymeric conglomeration generally composed of extracellular biopolymers in various structural forms. (wikipedia.org)
  • Hyperthermophilic archaeon Pyrobaculum calidifontis produce bundling pili which are homologous to the bacterial TasA filaments, a major component of the extracellular matrix in bacterial biofilms, which contribute to biofilm stability. (wikipedia.org)
  • Besides, electron storage was found in the form of biopolymers, both extracellular and intracellular, which opens new niches for BESs. (sense.nl)
  • Differences in architecture and cell-surface morphology were observed in biofilms formed by the M1- and M41-wild-type strains, accompanied by varying amounts of deposited extracellular matrix and differences in cell-to-cell junctions within each biofilm. (cdc.gov)
  • Biofilms are sessile microbial communities growing on surfaces, frequently embedded in a matrix of extracellular polymeric substances (also known as slime). (medscape.com)
  • Importantly, all Scl1-negative mutants examined showed significantly decreased ability to form biofilm in vitro. (cdc.gov)
  • SEM results showed concentration dependent reduction in biofilm and hyphae formation. (hindawi.com)
  • This study correlates the activity of the quorum sensing inhibitors with viscoelastic changes in the P. aeruginosa biofilm on the air-medium interface. (aiche.org)
  • The functioning of the EPS matrix in holding cells of Pseudomonas aeruginosa together and forming the mature biofilms. (ukessays.com)
  • The microcarriers made up of dextrons in the range of 60-90µm in size are used as a surface for Pseudomonas aeruginosa to form biofilms. (ukessays.com)
  • One problem with relying on sputum samples to guide therapy is that biofilm bacteria may not be adequately sampled via sputum, since sputum expectoration only samples P. aeruginosa that have detached and dispersed from the airway biofilm 5 , 6 . (ersjournals.com)
  • In vitro studies have shown thatbiofilm-forming P. aeruginosa are significantly less susceptible to antibiotics compared to nonadherent forms 3 , 7 . (ersjournals.com)
  • Thus, it is possible that PSB may directly recover P. aeruginosa bacteria that have aggregated as biofilms and adhered to the surface of the airway. (ersjournals.com)
  • The purpose of the present study was to determine whether the PSB can sample directly from the airway biofilm and, thus, more accurately represent the state of P. aeruginosa in CF patients' lungs. (ersjournals.com)
  • This study investigated ability of NTHi to form biofilms and its impact on airway epithelia using in vivo and in vitro analyses. (nih.gov)
  • NTHi formed biofilms on the apical surface of cultured airway epithelia. (nih.gov)
  • However, studies have not previously been done to determine whether bacteria retrieved from sputum are more susceptible to antibiotics compared to bacteria retrieved directly from the airway biofilm. (ersjournals.com)
  • The genes responsible for the biofilm formation are quantified by comparing the planktonic and biofilm samples. (ukessays.com)
  • One of its main virulence factors is its ability to form viscous, alginate-encased biofilms within the pulmonary mucus. (aiche.org)
  • The ability to form biofilms within its host ensures the success of the bacteria's reproduction cycle and eventual secretion of cholera toxin, 1 of 2 virulence factors that contribute to 21,000 to 143,000 cholera deaths worldwide each year. (asm.org)
  • The unique ability of the organism is forming biofilm. (ukessays.com)
  • The biofilms are formed by the organism with the association with a surface. (ukessays.com)
  • Furthermore, the Scl1 protein expressed on the surface of a heterologous host, Lactococcus lactis, was sufficient to induce biofilm formation by this organism. (cdc.gov)
  • Subpopulations of cells within the biofilm differentiate to perform various activities for motility, matrix production, and sporulation, supporting the overall success of the biofilm. (wikipedia.org)
  • The microbial diversity of biofilm communities of central venous catheters was not satisfactory examined. (muni.cz)
  • Bacteria that build up on biomedical devices (e.g. catheters) and industrial and agricultural pipes and drains in the form of biofilms are difficult to remove and can be resistant to biocides and antibiotics. (sciencedaily.com)
  • The ability of bacteria to aggregate and form biofilms impairs phagocytosis by polymorphonuclear leukocytes (PMNs). (ku.dk)
  • We studied, for the first time, the effects of mutants defective in biomineralization and calcite formation on biofilm development, resilience and morphology. (nature.com)
  • Gammarus minus has both cave and surface forms that differ considerably in their morphology. (auckland.ac.nz)
  • The aim of this study was to examine if the size of aggregates is critical for successful phagocytosis and how bacterial biofilms evade phagocytosis. (ku.dk)
  • None of the antibacterials exerted a significant effect on the in vitro susceptibility of the yeasts to the antifungal agents or on their ability to form biofilms. (bvsalud.org)
  • Bacterial ability to form biofilms was verified using a crystal violet colorimetric assay and testing cell viability by real-time quantitative PCR and Plate Count assay. (frontiersin.org)
  • isolated from vaginal and IUD string samples of women with IUDs, and (ii) to investigate the relationship between biofilm production and antifungal resistance. (who.int)