• Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.com)
  • The antibody has been negatively preadsorbed using a non-phosphopeptide corresponding to the site of phosphorylation to remove antibody that is reactive with non-phosphorylated Rb protein. (abcam.cn)
  • The survival prognosis of human papillomavirus (HPV)-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) is largely different, and little is known about the anti-tumor mechanism of tumor-infiltrated exhausted CD8 + T cells (Tex) in HNSCC. (elifesciences.org)
  • The goal of this study was to investigate the anti-cancer mechanism of EOPK in HCT116 colorectal cancer cells. (biomedcentral.com)
  • Together, our findings suggest a promising role for P-Tex cells in the prognosis of patients with HPV-positive HNSCC by providing modest but persistent anti-tumor effects. (elifesciences.org)
  • Further, a recent report on the effects of EOPK indicated that the oil has anti-obesity and hypolipidemic activity in vitro and in vivo , using 3 T3-L1 cells and high fat diet-fed rats [ 16 ]. (biomedcentral.com)
  • It has been reported that Alisma orientale has a protective effect on acute lung injury through an anti-inflammatory effect by repressing the NF-kappa B pathway [ 20 ]. (hindawi.com)
  • anti-hyperlipidemic effect through the up-regulation of the low-density lipoprotein receptor and the inhibition of acyl-coenzyme A [ 15 ]. (biomedcentral.com)
  • In the glioma cells, EIF5B promotes cell survival by enhancing the translation of several IRES-containing mRNAs including those encoding anti-apoptotic proteins such as XIAP and Bcl-xL [ 4 ]. (techscience.com)
  • Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. (abcam.com)
  • Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.co.jp)
  • HSP90 is a conserved molecular chaperone that regulates the stability, activation and maturation of more than 200 client proteins including receptor tyrosine kinases (HER2, EGFR, IGF-1R, MET), transcription factors (HIF1, TP53), signalling proteins (AKT, SRC) and cell cycle regulatory proteins (CDK4, CDK6). (biomedcentral.com)