Isoeugenol (2-methoxy-4-(prop-1-en-1-yl)phenol), a component of from clove (Eugenia caryophylata) oil, is a starting material for both the biotechnological and synthetic production of vanillin and vanillic acid. (researchgate.net)
Methyl1
Data in the dossier show that molnupiravir, [(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hyroxyamino)-2- oxopyrimidin-1-yl]oxolan-2-yl]methyl-2-methylpropanoate, is a white to an off-white crystalline powder that is freely soluble in methanol. (who.int)
Hydroxymethyl1
A dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. (mcw.edu)
Amino1
1,5-Dihydroxy-4-((1-methylethyl)amino)-8-nitroanthraquinone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. (sielc.com)
3alpha2
The systematic name of this enzyme class is (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate:CoA ligase (AMP-forming). (wikipedia.org)
Other names in common use include 3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase, DHCA-CoA ligase, and 3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming). (wikipedia.org)
TCDD for every step of the mechanism described for 2,3,7,8-TCDD carcinogenesis in humans including receptor binding, gene expression, protein activity changes, cellular replication, oxidative stress, promotion in initiation-promotion studies and complete carcinogenesis in laboratory animals. (who.int)
Synthetic1
There total 3 articles about Ethanone, 1-(2,5-dihydroxy-3,4,6-trimethylphenyl)- which guide to synthetic route it. (lookchem.com)
Content1
Moreover, we revealed the ability of proadifen to increase the intracellular hypericin content in HT-29 cells most likely via the inhibition of BCRP and MRP1 transporters ( 8 ). (spandidos-publications.com)
Compounds1
Pharmacological researches and clinical studies have indicated that Polygonum cuspidatum extraction and its major compounds possess antitumor [ 3 ], anti-inflammatory, antivirus, antimicrobial, neuroprotective, and cardioprotective activities [ 4 ]. (hindawi.com)
4. The notifier shall transfer the physical possession or control of the substance only to a person who will use it in accordance with section 3. (gc.ca)
Date1
Assessments published before this date expire after 3 years. (pharosproject.net)
Potential1
It was previously reported that proadifen (SKF-525A), a well-known cytochrome P450 monooxygenase inhibitor, not only has anti-proliferative potential in some cancer cell lines, but it is also able to inhibit BCRP and MRP1 transporter proteins ( 8 ). (spandidos-publications.com)
Years1
however, in children younger than 3 years, physicians misdiagnose as many as 20% of fractures caused by abuse. (medscape.com)
Pyrene1
BP- DNA adducts measured by (+/-)r7, t8-dihydroxy-c9,t10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene- DNA chemiluminescence immunoassay, also showed inter-individual variation of 3-58 BP- DNA adducts/10(8) nucleotides in NHMECs exposed only to BP. (cdc.gov)
Compounds1
These results suggest both pre- and postsynaptic actions of 7-OH-DPAT along with a lack of specificity of the various pharmacological compounds for the D(3) receptor. (nih.gov)
Inhibitors2
These agents are competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the early rate-limiting step in cholesterol biosynthesis, conversion of HMG-CoA to mevalonate. (nih.gov)
Column chromatography of an active fraction gave C_1 and C_2 inhibitors, so called (±)-p-menthane-3,8-cis-diol and (±)-p-menthane-3,8-trans-diol, respectively. (go.jp)
Vitamin5
Vitamin D(3), which exerts its effect through vitamin D receptor (VDR), is known for its potent immunomodulatory activities. (nih.gov)
Associations between low serum vitamin D(3) levels and increased risk of tuberculosis have been reported. (nih.gov)
Plasma 1,25 dihydroxy vitamin D(3) levels (1,25(OH)(2) D(3)) and ex vivo levels of VDR protein from peripheral blood mononuclear cells were studied in 65 pulmonary tuberculosis (PTB) patients and 60 normal healthy subjects (NHS) using enzyme-linked immunosorbent assay-based methods. (nih.gov)
Using real-time polymerase chain reaction (PCR), induction of VDR, cathelicidin, and CYP27B1 mRNA were studied in live Mycobacterium tuberculosis-stimulated macrophage cultures treated with or without 1,25 dihydroxy vitamin D(3). (nih.gov)
8. Combined antitumor effects of 1,25‑dihydroxy vitamin D3 and Notch inhibitor in liver cancer . (nih.gov)
Oxidative stress1
The diverse mechanisms are involved in the ethanol-induced hepatotoxicity while accumulating evidence shows the importance of oxidative stress mediated by reactive nitrogen species (RNS) or reactive oxygen species (ROS) [ 3 ]. (hindawi.com)
Protein5
1,25(OH)(2) D(3) were significantly increased (p = 0.0004), while ex vivo levels of VDR protein were significantly decreased in PTB patients (p = 0.017) as compared to NHS. (nih.gov)
3. Romidepsin hepatocellular carcinoma suppression in mice is associated with deregulated gene expression of bone morphogenetic protein and Notch signaling pathway components. (nih.gov)
A type 3 copper protein that catalyses exclusively the oxidation of catechol (i.e., o -diphenol) to the corresponding o -quinone. (enzyme-database.org)
To date, SPP1 (osteopontin) 8 and LTBP4 (latent TGF-β binding protein 4) 9 have been identified as genetic modifiers in both human DMD and murine models of disease. (nature.com)
Enzymes1
These three reactions are catalyzed by very large, multi-subunit enzymes prolyl 4-hydroxylase , prolyl 3-hydroxylase and lysyl 5-hydroxylase , respectively. (wikipedia.org)
Occurs1
[8] Hydroxylation occurs at the γ-C atom, forming hydroxyproline (Hyp), which stabilizes the secondary structure of collagen due to the strong electronegative effects of oxygen. (wikipedia.org)
Receptors1
The five types of dopamine (DA) receptor subtypes have been grouped into two families, the D(1)-like (D(1) and D(5) receptors) and D(2)-like (D(2), D(3), and D(4) receptors). (nih.gov)
Vivo1
Differences in the relative amounts of hydrolysis products and DNA adducts derived from anti- and syn-dihydrodiolepoxides following application of BP-7,8-diol to mouse skin in vivo indicate peroxyl radicals play a significant role in metabolism of BP-7,8-diol in uninduced animals. (nih.gov)
Research1
We supply 5,7-Dihydroxy-3,4',8-trimethoxyflavone(CAS#1570-09-8) with high quality for research purpose. (albtechnology.com)
Type1
Gerdemann, C., Eicken, C. and Krebs, B. The crystal structure of catechol oxidase: new insight into the function of type-3 copper proteins. (enzyme-database.org)