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  • endothelial
  • For this, sucrose intake test, immunohistochemistry for 5-bromo-2'-deoxyuridine, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling staining, and Western blot analysis for brain-derived neurotrophic factor, cyclic adenosine monophosphate response element binding protein, and endothelial nitric oxide synthase were conducted. (nih.gov)
  • Animals
  • The animals in the CMS groups were exposed to the CMS conditions for 8 weeks and those in the control group were exposed to the control conditions for 8 weeks.Treadmill exercise restored sucrose consumption, increased cell proliferation, and decreased apoptotic cell death.The present results suggest the possibility that exercise may improve symptoms of depression. (nih.gov)
  • The animals in the CMS groups were exposed to the CMS conditions for 8 weeks and those in the control group were exposed to the control conditions for 8 weeks. (nih.gov)
  • levels
  • injury-induced increases in cyclic AMP and glutamate levels were also significantly reduced by a group II agonist. (aspetjournals.org)
  • Removal of the endothelium abolished adenosine triphosphate-, thrombin-, and trypsin-induced relaxation and the associated increased levels of cyclic nucleotides. (ahajournals.org)
  • mechanisms
  • 1 2 Furthermore, NO and NO donors have been shown to elicit a wide range of effects on myocardial contractility, 3 4 5 6 7 8 9 but the specific nature of the subcellular mechanisms underlying the diverse effects in heart is largely unknown. (ahajournals.org)
  • Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta. (ahajournals.org)
  • The mechanisms by which adenosine triphosphate, thrombin, and trypsin cause relaxation of vascular smooth muscle were investigated. (ahajournals.org)
  • significantly
  • 22 23 24 25 Recent reports show that under certain conditions, NO donors are able to enhance myocardial contractility, 8 9 and that the basal intracardiac production and release of NO significantly augments the Frank-Starling response in the isolated heart. (ahajournals.org)
  • increase
  • Human chorionic gonadotropin and 8-bromo cyclic adenosine monophosphate promote an acute increase in cytochrome P450scc and adrenodoxin messenger RNAs in cultured human. (naver.com)
  • 8 An increase in excitation in the superficial dorsal horn induces the activation of PKA and PKC, eventually leading to the activation of ERK signaling. (asahq.org)
  • addition
  • Addition of 8-bromo-cGMP (10(-3) mol/1) stimulated the current to 290 +/- 57% (n = 4) of the original level, charybdotoxin led to a reduction of this current to 156 +/- 28% of the initial value. (arvojournals.org)