4 glucan transferase. Medical search. Frequent questions

McArdle disease is caused by a deficiency of myophosphorylase (alpha-1,4-glucan orthophosphate glycosyl transferase). (medscape.com)
Lichenase, also known as 1,3-1,4-beta-glucanase, is a member of glycosyl hydrolase family 16, that specifically cleaves 1,4-beta-D-glucosidic bonds in mixed-linked beta glucans that also contain 1,3-beta-D-glucosidic linkages. (unl.edu)
McArdle disease is caused by a deficiency of myophosphorylase (alpha-1,4-glucan orthophosphate glycosyl transferase), which normally initiates glycogen breakdown by removing 1,4-glucosyl groups from glycogen with the release of glucose-1-phosphate. (medscape.com)

The specificity of α-amylase (EC 3.2.1.1), which hydrolyses the α-1,4-glucosidic linkages in starch and related α-glucans, is the best known representative of a large group of starch hydrolases and related amylolytic enzymes. (or.jp)
The α-amylase family was originally created early in 1990s based on several crucial scientific observations, pioneering discoveries and efforts, such as sharing sequence similarities among different α-glucan-active enzymes within the same predicted fold of their catalytic domain, identifying the functionally versatile enzyme named neopullulanase and creating the classification of glycoside hydrolases (GHs) into sequence-based families. (or.jp)
In addition to enzymes from hydrolases, transferases and isomerases, it contains also some non-enzymatic proteins involved in amino acid transport. (or.jp)
At present the α-amylase enzyme family covers 27 different enzyme specificities from hydrolases (EC 3), transferases (EC 2) and isomerases (EC 5). (go.jp)

This subfamily also includes bacterial alpha amylases and 1,4-alpha-glucan branching enzymes which are highly similar to MTHase. (unl.edu)
Glycogen debranching enzymes have both 4-alpha-glucanotransferase and amylo-1,6-glucosidase activities. (unl.edu)
Isoamylase is one of the starch-debranching enzymes that catalyze the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen. (unl.edu)
Finally, it is probable that the specificity of α-amylase is present also in the family GH126, although biochemical evidence is still unclear with regard to the endo- vs. exo-mode of action of the only characterized "amylase" from Clostridium perfringens, which, moreover, exhibits a structural homology with β-glucan-active enzymes employing inverting reaction mechanism. (or.jp)
Thus the debranching enzymes, transferase and α-1,6- glucosidase converts the branched glycogen structure into a linear one, paving the way for further cleavage by phosphorylase. (wikidoc.org)

As a glucosidase, it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. (unl.edu)
Phosphorylase can only cleave α-1,4- glycosidic bond between adjacent glucose molecules in glycogen but branches exist as α-1,6 linkages. (wikidoc.org)

[ 1 , 2 ] In healthy individuals, myophosphorylase initiates glycogen breakdown by removing 1,4-glucosyl groups from glycogen with the release of glucose-1-phosphate (see image below). (medscape.com)

α-1, 4-Glucan lyase (EC 4.2.2.13) produces 1, 5-anhydro D-fructose from α-1, 4-linked glucose oligomers and polymers, such as maltose, maltosaccharides, starch and glycogen. (go.jp)
4-α-D-glucanotransferase ( EC 2.4.1.25 ), or glucosyltransferase , transfers three glucose residues from the four-residue glycogen branch to a nearby branch. (wikidoc.org)

Crystal structures are available for archaeal and bacterial NAS-like proteins that carry out simpler aminobutanoyl transferase reactions. (bvsalud.org)

Xyloglucan is a soluble hemicellulose with a backbone of beta-1,4-linked glucose units, partially substituted with alpha-1,6-linked xylopyranose branches. (unl.edu)

Cys-enriched domain related to a novel plant carbohydrate-binding module is essential for the glucan-transferase activity of a PHR/GEL/GAS protein subfamily glucan-transferase activity of a PHR/GEL/GAS protein subfamily. (unimi.it)

In E. coli glgX selectively catalyzes the cleavage of 4-subunit branches, without the action of glucanotransferase. (wikidoc.org)

As a transferase, it transfers a segment of the 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. (unl.edu)

GPI biosynthesis is a conserved process, required for anchoring proteins to the plasma membrane of fungi and thus essential for the integrity of the fungal cell wall in yeasts and molds 4 . (nature.com)

In enzymology, a polysaccharide O-methyltransferase (EC 2.1.1.18) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + 1,4-alpha-D-glucooligosaccharide ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units Thus, the two substrates of this enzyme are S-adenosyl methionine and 1,4-alpha-D-glucooligosaccharide, whereas its two products are S-adenosylhomocysteine and oligosaccharide containing 6-methyl-D-glucose units. (wikipedia.org)

[ 4 ] In 1959, myophosphorylase was discovered, and its activity was found to be absent in individuals with McArdle disease. (medscape.com)
The lyase is highly specific toward α-1, 4-glucosidic bonds and shows negligible activity toward α-1, 6-glucosidic bonds. (go.jp)

Chitin is an hexosamine polymer composed of beta-(1,4)-linked linear chains of more than 5,000 N-acetylglucosamine residues that are highly cross-linked with hydrogen bonds. (biomedcentral.com)

Combined biochemical, bioinformatic, and morphological data conclusively established for the first time that XXT3, together with XXT4 and XXT5, adds xylosyl residue specifically at the third glucose in the glucan chain to synthesize XXXG-type XyGs. (bvsalud.org)

NOV1 cleaves a wide range of stilbene-like compounds with a 4′-OH group, offering potential in processing some solubilized fragments of lignin into monomer aromatic compounds. (jbei.org)

The members of the α-amylase family GH13 employ a retaining reaction mechanism, share 4-7 conserved sequence regions (CSRs) and adopt a TIM-barrel domain with the GH13 catalytic machinery. (or.jp)

The systematic name of this enzyme class is S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase. (wikipedia.org)
MTSase is responsible for converting the alpha-1,4-glucosidic linkage to an alpha,alpha-1,1-glucosidic linkage at the reducing end of the maltooligosaccharide through an intramolecular transglucosylation reaction, while MTHase hydrolyzes the penultimate alpha-1,4 linkage of the reducing end, resulting in the release of trehalose. (unl.edu)
In E. coli , Glucose transfer is performed by 4-alpha-glucanotransferase, a 78.5 kDa protein coded for by the gene malQ. (wikidoc.org)

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. (wikipedia.org)

Natural substrates of beta-glucanase are beta-glucans from grain endosperm cell walls or lichenan from the Islandic moss, Cetraria islandica. (unl.edu)

Cluster Dextrin TM is a trademarked form of Highly Branched Cyclic Dextrin that is a new type of dextrin that is produced from amylopectin via cyclization reaction of a branching enzyme (BE,1,4-α-D-glucan: 1,4-α-D-glucan 6-α-D-(1,4-α-D-glucano)-transferase,EC 2.4.1.18). (musclefeast.com)

stimulation of plant resistance mechanisms and development [4, 5]. (123dok.org)
The BNS and modulation of plant defense in response to BNS is not well understood 4 . (nature.com)

The phytohormone precursor OPDA is isomerized in the insect gut by a single, specific glutathione transferase. (mpg.de)
15. Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress. (nih.gov)
Genotype analysis indicates that farmers with certain "unfavorable" versions of polymorphic metabolizing genes (cytochrome P4502E1, the glutathione S-transferases mu and theta, and the paraoxonase genes) had significantly more biological effects, as determined by all three cytogenetic assays, than both the farmers with the "favorable" alleles and the matched controls. (nih.gov)
Levels of xenobiotic metabolizing enzymes such as cytochrome (Cyt) P450 and Cyt b5, activities of reduced glutathione (GSH), glutathione-S-transferase (GST), aspartate aminotransaminase (AST), alanine aminotransaminase (ALT) and alkaline phosphatase (ALP), and total protein and cholesterol content in the liver tissues were measured to determine the hepatotoxicity caused by DENA. (jcimjournal.com)
We also observed a significant increase in lactate dehydrogenase (LDH), Lipid peroxidation (LPO), glutathione peroxidase (GPx) activity, glutathione reductase (GR) activity, catalase (CAT) activity, Na(+)K(+)ATPase activity, and glutathione S transferase (GST) activity along with significant decreased levels of glutathione (GSH) content in diabetic rats. (mushroomreferences.com)
Glutathione S-transferase (GST) is a major enzyme system that captures electrophiles (reactive carcinogenic compounds), and metabolizes xenobiotics (toxic elements from drugs, pesticides, etc. (peak-health-now.com)

Immunity or digestion: glucanase activity in a glucan-binding protein family from lepidoptera. (mpg.de)

oligo-1,4-->1,4-glucantransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33). (unl.edu)
Glycogen debranching enzymes have both 4-alpha-glucanotransferase and amylo-1,6-glucosidase activities. (unl.edu)
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. (nih.gov)
This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. (nih.gov)

In enzymology, a polysaccharide O-methyltransferase (EC 2.1.1.18) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + 1,4-alpha-D-glucooligosaccharide ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units Thus, the two substrates of this enzyme are S-adenosyl methionine and 1,4-alpha-D-glucooligosaccharide, whereas its two products are S-adenosylhomocysteine and oligosaccharide containing 6-methyl-D-glucose units. (wikipedia.org)
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. (wikipedia.org)
The systematic name of this enzyme class is S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase. (wikipedia.org)
In glycogen or amylopectin synthesis, the enzyme that catalyzes the transfer of a segment of a 1,4-alpha-glucan chain to a primary hydroxy group in a similar glucan chain. (nih.gov)
Cluster Dextrin® (Highly Branched Cyclic Dextrin) is a new type of dextrin that is produced from amylopectin via a cyclization reaction of a branching enzyme (BE, 1,4-α-D-glucan: 1,4-α-D-glucan 6-α-D-(1,4-α-D-glucano)-transferase, EC 2.4.1.18). (moxilife.com)
An enzyme that catalyzes the transfer of D-glucose from UDPglucose into 1,4-alpha-D-glucosyl chains. (bvsalud.org)

Site directed mutagenesis studies in S. cerevisiae indicate that the transferase and glucosidase activities are independent and located in different regions of the polypeptide chain. (unl.edu)
Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family [Carbohydrate transport and metabolism]. (unl.edu)
As a glucosidase, it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. (unl.edu)

12. Candida albicans β-Glucan-Containing Particles Increase HO-1 Expression in Oral Keratinocytes via a Reactive Oxygen Species/p38 Mitogen-Activated Protein Kinase/Nrf2 Pathway. (nih.gov)
adenylate kinase 4 [Source:HGNC Sym. (gsea-msigdb.org)

Periplasmic glucan biosynthesis protein [Interproscan]. (ntu.edu.sg)
protein_coding" "Cz05g23010.t1","No alias","Chromochloris zofingiensis","4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Interproscan]. (ntu.edu.sg)
CoA-transferase family III [Interproscan]. (ntu.edu.sg)

C-X-C motif chemokine receptor 4 [S. (gsea-msigdb.org)

Isoamylase is one of the starch-debranching enzymes that catalyze the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen. (unl.edu)

As a transferase, it transfers a segment of the 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. (unl.edu)

Akramiene D, Kondrotas A, Didziapetriene J, Kevelaitis E. Effects of beta-glucans on the immune system. (gmushrooms.com)

In higher plants, lignin is derived from the carbon skeleton of phenylalanine by sequential conversion and complex polymerization, and is an aromatic heteropolymer primarily consisting of guaiacyl (G), syringyl (S), and p -hydroxyphenyl (H) unit [ 4 ]. (biomedcentral.com)

2018 Oct;21(4):365-368. (nih.gov)

DLG associated protein 4 [Source:HG. (gsea-msigdb.org)
dipeptidyl peptidase 4 [Source:HGNC. (gsea-msigdb.org)

4. Some strings, including lengthy descriptions of things such as procedures, health activities or medical devices, are so complicated that it is again unlikely to find them in normal text. (nih.gov)

4. 7,8-Dihydroxyflavone protects human keratinocytes against oxidative stress-induced cell damage via the ERK and PI3K/Akt-mediated Nrf2/HO-1 signaling pathways. (nih.gov)

Overexpression of PtoMYB115 altered lignin biosynthetic gene expression, resulting in reduced lignin deposition, raised S/G and beta- O -4 linkage, resulting in a significant reduction in cellulase adsorption with lignin and an increment in cellulose accessibility. (biomedcentral.com)

Frequent feeds (every 3-4 hours) are needed to maintain euglycemia in infancy. (nih.gov)
for first 3 to 4 hours of exercise. (moxilife.com)

Anatomy14

Organisms28

Diseases4

Chemicals and Drugs134

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Phenomena and Processes47

Technology, Industry, Agriculture2

Information Science5

Health Care1

Glycosyl3

Hydrolases4

Enzymes5

Linkages2

Glucose-1-phospha1

Glycogen2

Reactions1

Backbone1

Carbohydrate1

Subunit1

Transfers1

Proteins1

Catalyzes1

Activity2

Bonds1

Chain1

Compounds1

Conserved sequence1

Alpha3

Family1

Beta1

Type1

Plant2

Glutathione6

Binding protein1

Amylo-1,6-glucosidase4

Enzyme6

Glucosidase3

Kinase2

Interproscan3

Motif1

Enzymes1

Segment1

Immune1

Complex1

20181

Source2

Activities1

Cell1

Significant1

Hours2